| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.134118 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.10791 |
| B2M | beta-2-microglobulin | 0.0791209 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0737095 |
| PLAU | plasminogen activator, urokinase | 0.0696531 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0667995 |
| MACC1 | metastasis associated in colon cancer 1 | 0.064252 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0631905 |
| HLA-A | major histocompatibility complex, class I, A | 0.0612557 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0598325 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0588525 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0575705 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0567992 |
| POTEF | POTE ankyrin domain family, member F | 0.0564866 |
| PTMA | prothymosin, alpha | 0.0559065 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0554533 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0551468 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0549717 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0528001 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0526967 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0523614 |
| MUC4 | mucin 4, cell surface associated | 0.0521818 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0511269 |
| OPTN | optineurin | 0.047078 |
| HLA-B | major histocompatibility complex, class I, B | 0.0465831 |
| CD2AP | CD2-associated protein | 0.0463558 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0463286 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0458167 |
| LDHA | lactate dehydrogenase A | 0.0448876 |
| GOLGB1 | golgin B1 | 0.0432786 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0432718 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0431639 |
| MYOF | myoferlin | 0.0421623 |
| JMJD1C | jumonji domain containing 1C | 0.0411705 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0411638 |
| CCNL1 | cyclin L1 | 0.0411112 |
| CD47 | CD47 molecule | 0.041083 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0409802 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0393304 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0381035 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0378118 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0378046 |
| BICC1 | BicC family RNA binding protein 1 | 0.0376582 |
| FNIP1 | folliculin interacting protein 1 | 0.0376377 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0374837 |
| TXNRD1 | thioredoxin reductase 1 | 0.0374397 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0368477 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0366528 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0361155 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0361091 |
| ANXA2 | annexin A2 | 0.0355735 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0352137 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0345154 |
| EZR | ezrin | 0.0345023 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0337813 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0336964 |
| CLTC | clathrin, heavy chain (Hc) | 0.0335248 |
| TGM2 | transglutaminase 2 | 0.0331495 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0330955 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0327336 |
| DSTN | destrin (actin depolymerizing factor) | 0.0326782 |
| F11R | F11 receptor | 0.0322386 |
| APP | amyloid beta (A4) precursor protein | 0.0318652 |
| ANXA4 | annexin A4 | 0.0318233 |
| UBC | ubiquitin C | 0.0316175 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0314609 |
| MCU | mitochondrial calcium uniporter | 0.031366 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.030995 |
| DENND4A | DENN/MADD domain containing 4A | 0.0308218 |
| EHBP1 | EH domain binding protein 1 | 0.0307337 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0300588 |
| TMEM165 | transmembrane protein 165 | 0.0300077 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0299492 |
| BPTF | bromodomain PHD finger transcription factor | 0.0297532 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0297104 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0296234 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0296013 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0296007 |
| APOL1 | apolipoprotein L, 1 | 0.0292341 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0286171 |
| WWC1 | WW and C2 domain containing 1 | 0.0286154 |
| DSPP | dentin sialophosphoprotein | 0.0285441 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284956 |
| SHROOM3 | shroom family member 3 | 0.0284728 |
| PAPOLA | poly(A) polymerase alpha | 0.0281826 |
| FOSL1 | FOS-like antigen 1 | 0.0281265 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280268 |
| FNBP4 | formin binding protein 4 | 0.0277358 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0273812 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0273478 |
| BRD2 | bromodomain containing 2 | 0.027317 |
| YTHDC1 | YTH domain containing 1 | 0.0272944 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.027135 |
| PTEN | phosphatase and tensin homolog | 0.0269132 |
| ITGB8 | integrin, beta 8 | 0.0266777 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0265171 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265145 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0264775 |
| RBM39 | RNA binding motif protein 39 | 0.0264094 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0263213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.175918 |
| MT2A | metallothionein 2A | -0.138936 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127957 |
| MT1X | metallothionein 1X | -0.0834381 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0499641 |
| TMSB10 | thymosin beta 10 | -0.0473946 |
| AHNAK | AHNAK nucleoprotein | -0.0456797 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0452424 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0450008 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0395507 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385629 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0382677 |
| DTNA | dystrobrevin, alpha | -0.0358403 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0352194 |
| MMP7 | matrix metallopeptidase 7 | -0.0348373 |
| FTL | ferritin, light polypeptide | -0.0344497 |
| H1-0 | H1.0 linker histone | -0.0329156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0326316 |
| PCDH7 | protocadherin 7 | -0.0315647 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299934 |
| STK17A | serine/threonine kinase 17a | -0.0292187 |
| USP3 | ubiquitin specific peptidase 3 | -0.0282091 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0280297 |
| STC1 | stanniocalcin 1 | -0.0274757 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0268127 |
| RRBP1 | ribosome binding protein 1 | -0.0263328 |
| NCKAP5 | NCK-associated protein 5 | -0.0256417 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0246968 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0244793 |
| ACTN1 | actinin, alpha 1 | -0.0231312 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0230155 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0229725 |
| HPCAL1 | hippocalcin-like 1 | -0.0228213 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0227425 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0225516 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0221135 |
| LAMC2 | laminin, gamma 2 | -0.021943 |
| ATXN1 | ataxin 1 | -0.0216017 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0214676 |
| RAD51B | RAD51 paralog B | -0.0200794 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0200091 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0199689 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0194087 |
| ANXA1 | annexin A1 | -0.0189992 |
| HLA-C | major histocompatibility complex, class I, C | -0.0182277 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0180077 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0178374 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0174885 |
| SDC4 | syndecan 4 | -0.0169716 |
| FAM107B | family with sequence similarity 107, member B | -0.0169164 |
| TGFB1 | transforming growth factor, beta 1 | -0.016749 |
| FRMD6 | FERM domain containing 6 | -0.0166149 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0161867 |
| LASP1 | LIM and SH3 protein 1 | -0.0159274 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0157015 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0156186 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0155833 |
| CMIP | c-Maf inducing protein | -0.0155306 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0153631 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0153274 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0152529 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0152337 |
| ACTN4 | actinin, alpha 4 | -0.0152266 |
| FAM110C | family with sequence similarity 110, member C | -0.0149727 |
| RNF213 | ring finger protein 213 | -0.014826 |
| AFDN | afadin, adherens junction formation factor | -0.0147746 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0146988 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0144207 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0143429 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0141425 |
| ASPH | aspartate beta-hydroxylase | -0.0140883 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0140776 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0140202 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0139662 |
| ITGA1 | integrin, alpha 1 | -0.0139201 |
| IRS2 | insulin receptor substrate 2 | -0.0138489 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0138044 |
| RASA3 | RAS p21 protein activator 3 | -0.0137806 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0133711 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0133428 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0131437 |
| RPS19 | ribosomal protein S19 | -0.0130361 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0128563 |
| CAPRIN2 | caprin family member 2 | -0.0128419 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0128084 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0127697 |
| CAVIN1 | caveolae associated protein 1 | -0.012764 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0127629 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0127395 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0121555 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0121506 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0121018 |
| PLEC | plectin | -0.0119428 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0118996 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0117881 |
| S100A10 | S100 calcium binding protein A10 | -0.0117218 |
| FRMD4A | FERM domain containing 4A | -0.0115888 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0115556 |
| NAV1 | neuron navigator 1 | -0.0115138 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0115053 |
