| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCAM2 | neural cell adhesion molecule 2 | 0.082481 |
| BPTF | bromodomain PHD finger transcription factor | 0.0691874 |
| FMN1 | formin 1 | 0.0656464 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.061259 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0576884 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0568527 |
| DST | dystonin | 0.0524692 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.04988 |
| GPC5 | glypican 5 | 0.0458027 |
| VMP1 | vacuole membrane protein 1 | 0.0433714 |
| MYO6 | myosin VI | 0.040142 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0399518 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0395521 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0394685 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0379241 |
| PTEN | phosphatase and tensin homolog | 0.0378643 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0373034 |
| FN1 | fibronectin 1 | 0.0363288 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0349558 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0343786 |
| PCBP2 | poly(rC) binding protein 2 | 0.034116 |
| PLAT | plasminogen activator, tissue | 0.0339558 |
| KLHL13 | kelch-like family member 13 | 0.0339548 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.033367 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0328088 |
| CTBP2 | C-terminal binding protein 2 | 0.0322645 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0311855 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0307437 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0296971 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0293256 |
| USP34 | ubiquitin specific peptidase 34 | 0.0292541 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0288588 |
| EXT1 | exostosin glycosyltransferase 1 | 0.028574 |
| DPH6 | diphthamine biosynthesis 6 | 0.0285304 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0284072 |
| MED13L | mediator complex subunit 13-like | 0.0283383 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.028085 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0280604 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0279878 |
| CLTC | clathrin, heavy chain (Hc) | 0.0279513 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0275902 |
| STC1 | stanniocalcin 1 | 0.0275682 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0275436 |
| POTEF | POTE ankyrin domain family, member F | 0.0272841 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.027254 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0271438 |
| AHR | aryl hydrocarbon receptor | 0.0270113 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0269823 |
| BBX | bobby sox homolog (Drosophila) | 0.026722 |
| PRRX1 | paired related homeobox 1 | 0.0267195 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0265143 |
| SMAD3 | SMAD family member 3 | 0.0265082 |
| VCL | vinculin | 0.0264727 |
| FMNL2 | formin-like 2 | 0.0262707 |
| TBC1D5 | TBC1 domain family, member 5 | 0.026081 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0257154 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0256214 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0252966 |
| MCL1 | myeloid cell leukemia 1 | 0.0251572 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0250745 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0250161 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0250062 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0249893 |
| AEBP2 | AE binding protein 2 | 0.0249222 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0249042 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246656 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.024411 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0243381 |
| ACTN1 | actinin, alpha 1 | 0.024213 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0241521 |
| IL6ST | interleukin 6 signal transducer | 0.0236864 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0236336 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0234626 |
| SIK3 | SIK family kinase 3 | 0.0232748 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0232308 |
| HDAC4 | histone deacetylase 4 | 0.0232181 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0232068 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0228417 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0227981 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0226791 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0226319 |
| ZYX | zyxin | 0.0225602 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0225109 |
| GLI3 | GLI family zinc finger 3 | 0.0223808 |
| PRKCA | protein kinase C, alpha | 0.0222225 |
| WDR43 | WD repeat domain 43 | 0.022208 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0221155 |
| FGF14 | fibroblast growth factor 14 | 0.022025 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0219728 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216708 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0216437 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0214844 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0214843 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0214565 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0213616 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0212563 |
| EXOC4 | exocyst complex component 4 | 0.0212024 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0208319 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0207545 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.020729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.0947158 |
| NRG1 | neuregulin 1 | -0.0792595 |
| MEF2A | myocyte enhancer factor 2A | -0.0786887 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0771945 |
| FAM13A | family with sequence similarity 13, member A | -0.0761494 |
| HELZ | helicase with zinc finger | -0.0743147 |
| RPS6 | ribosomal protein S6 | -0.0666576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0636979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0635112 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.054757 |
| WDR45B | WD repeat domain 45B | -0.0538194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0501896 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0492107 |
| RPLP1 | ribosomal protein, large, P1 | -0.0489369 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0478214 |
| TRIB2 | tribbles pseudokinase 2 | -0.0476847 |
| PTMA | prothymosin, alpha | -0.0460618 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0410599 |
| FNBP1 | formin binding protein 1 | -0.0407377 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0398264 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0388989 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0387169 |
| RPL38 | ribosomal protein L38 | -0.0386559 |
| RPL34 | ribosomal protein L34 | -0.0378684 |
| RPL23 | ribosomal protein L23 | -0.0365688 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0364432 |
| LMNA | lamin A/C | -0.0357853 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0356332 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0344198 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0342391 |
| HIP1 | huntingtin interacting protein 1 | -0.0341094 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336504 |
| GNAS | GNAS complex locus | -0.0334399 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0331329 |
| ACTG1 | actin gamma 1 | -0.0316355 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0303201 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0302387 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0298815 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0293566 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0291688 |
| RPS2 | ribosomal protein S2 | -0.0288402 |
| LPIN1 | lipin 1 | -0.028713 |
| AHNAK | AHNAK nucleoprotein | -0.0281551 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0280098 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0277521 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276916 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0274873 |
| RPL36 | ribosomal protein L36 | -0.0271339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267688 |
| CENPF | centromere protein F, 350/400kDa | -0.0266386 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0265382 |
| RPL19 | ribosomal protein L19 | -0.0260858 |
| S100A6 | S100 calcium binding protein A6 | -0.0260348 |
| HMGB2 | high mobility group box 2 | -0.0259908 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0259089 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0258638 |
| COL1A1 | collagen, type I, alpha 1 | -0.0258535 |
| CADM1 | cell adhesion molecule 1 | -0.0252313 |
| CCDC47 | coiled-coil domain containing 47 | -0.0250791 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.024957 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0248131 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0242858 |
| RPL35A | ribosomal protein L35a | -0.0242218 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0238765 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0238583 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0237242 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0236747 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.023576 |
| IER3 | immediate early response 3 | -0.0233291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0230531 |
| RBM25 | RNA binding motif protein 25 | -0.0230155 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0224931 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224732 |
| SP100 | SP100 nuclear antigen | -0.0224546 |
| RPL27 | ribosomal protein L27 | -0.0224493 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0223862 |
| MYO9B | myosin IXB | -0.0223145 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0222493 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0220855 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0220602 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0220212 |
| RPS27 | ribosomal protein S27 | -0.0216058 |
| CALD1 | caldesmon 1 | -0.0215297 |
| EVL | Enah/Vasp-like | -0.0213631 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0210552 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0209301 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0209289 |
| MRTFA | myocardin related transcription factor A | -0.0208702 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0205892 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0204281 |
| FLNB | filamin B, beta | -0.0203462 |
| CFDP1 | craniofacial development protein 1 | -0.0200506 |
| RFX7 | regulatory factor X, 7 | -0.0199938 |
| QKI | QKI, KH domain containing, RNA binding | -0.0197307 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0195827 |
| ATXN2L | ataxin 2-like | -0.0190081 |
| DIAPH1 | diaphanous-related formin 1 | -0.0189525 |
| RPS24 | ribosomal protein S24 | -0.0189075 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0188649 |
| NES | nestin | -0.0187768 |
