| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.218162 |
| MACC1 | metastasis associated in colon cancer 1 | 0.162594 |
| B2M | beta-2-microglobulin | 0.162123 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.155993 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.13318 |
| SPATA13 | spermatogenesis associated 13 | 0.12658 |
| MYO1E | myosin IE | 0.0997697 |
| ITGA6 | integrin, alpha 6 | 0.0957487 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0935471 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0918827 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.083901 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0818591 |
| LYZ | lysozyme | 0.0813345 |
| TMC5 | transmembrane channel-like 5 | 0.0735117 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0667064 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0663099 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0655585 |
| LCN2 | lipocalin 2 | 0.0621717 |
| EGR1 | early growth response 1 | 0.0607407 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0576028 |
| PTMA | prothymosin, alpha | 0.0562316 |
| SERINC5 | serine incorporator 5 | 0.0552391 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0551371 |
| ANXA2 | annexin A2 | 0.054923 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.053844 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0535778 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0534868 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0534645 |
| TRIM2 | tripartite motif containing 2 | 0.0518453 |
| EPHB2 | EPH receptor B2 | 0.0516838 |
| KLF6 | Kruppel-like factor 6 | 0.0500025 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0499938 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0487386 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0482755 |
| JUN | jun proto-oncogene | 0.0482019 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0479867 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0477274 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0476536 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0475232 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0474701 |
| MCU | mitochondrial calcium uniporter | 0.0470369 |
| HLA-E | major histocompatibility complex, class I, E | 0.0463423 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0458955 |
| RBM47 | RNA binding motif protein 47 | 0.0449796 |
| HLA-B | major histocompatibility complex, class I, B | 0.044498 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0443813 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0441651 |
| ERBIN | erbb2 interacting protein | 0.0427822 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0420534 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0418762 |
| HLA-A | major histocompatibility complex, class I, A | 0.041356 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0412996 |
| MX2 | MX dynamin-like GTPase 2 | 0.0411678 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0406541 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0403675 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0394598 |
| FNIP1 | folliculin interacting protein 1 | 0.0386733 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.037676 |
| EZR | ezrin | 0.0374082 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0370458 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0366488 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0358438 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0356228 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0350399 |
| LDHA | lactate dehydrogenase A | 0.0348409 |
| SP100 | SP100 nuclear antigen | 0.034612 |
| ENO1 | enolase 1, (alpha) | 0.0345476 |
| USP54 | ubiquitin specific peptidase 54 | 0.0343624 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0341506 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0332263 |
| ANXA4 | annexin A4 | 0.0327248 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0325374 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.032534 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0320563 |
| CLDN4 | claudin 4 | 0.0317612 |
| NCKAP5 | NCK-associated protein 5 | 0.0315265 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0304876 |
| TMEM62 | transmembrane protein 62 | 0.0304872 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0304806 |
| ABHD2 | abhydrolase domain containing 2 | 0.0304441 |
| CDHR2 | cadherin-related family member 2 | 0.0303353 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0302584 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0295573 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0293766 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0290577 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0290467 |
| SLK | STE20-like kinase | 0.029003 |
| SYT1 | synaptotagmin I | 0.0289266 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0288215 |
| ETV6 | ets variant 6 | 0.0286745 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0285003 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0282522 |
| MUC13 | mucin 13, cell surface associated | 0.0278328 |
| CD164 | CD164 molecule, sialomucin | 0.0277346 |
| MKI67 | marker of proliferation Ki-67 | 0.0275867 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0274149 |
| FTL | ferritin, light polypeptide | 0.0270095 |
| SPAG9 | sperm associated antigen 9 | 0.0270035 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.027001 |
| IRF1 | interferon regulatory factor 1 | 0.0268808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108975 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104624 |
| INTS6 | integrator complex subunit 6 | -0.0666215 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.055779 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0557641 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0550189 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0526241 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0497392 |
| IFNGR1 | interferon gamma receptor 1 | -0.0484332 |
| EFNB2 | ephrin-B2 | -0.0440265 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0429112 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0412666 |
| PLSCR2 | phospholipid scramblase 2 | -0.040385 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0401352 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0369897 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.036977 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0368858 |
| RNF43 | ring finger protein 43 | -0.0356532 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0353455 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0351484 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0341599 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0336728 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0335812 |
| SMAD3 | SMAD family member 3 | -0.0332894 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.032013 |
| AHNAK | AHNAK nucleoprotein | -0.0317413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0308658 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0304136 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0286771 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0282689 |
| VCL | vinculin | -0.0279315 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0276172 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0275903 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0270078 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0270075 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0269047 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0257448 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0251704 |
| RRBP1 | ribosome binding protein 1 | -0.0248342 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0243762 |
| TXNIP | thioredoxin interacting protein | -0.0243663 |
| SEC24D | SEC24 family member D | -0.0242025 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0241002 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0240864 |
| PRELID2 | PRELI domain containing 2 | -0.0238198 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.023646 |
| MATR3 | matrin 3 | -0.0232565 |
| ASPH | aspartate beta-hydroxylase | -0.0230541 |
| WDR26 | WD repeat domain 26 | -0.0226025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0222659 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.021935 |
| XPO1 | exportin 1 | -0.0217607 |
| HELZ | helicase with zinc finger | -0.0215826 |
| NF1 | neurofibromin 1 | -0.0214685 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0214549 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0211484 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0208823 |
| TUFT1 | tuftelin 1 | -0.0207597 |
| OGA | O-GlcNAcase | -0.0206091 |
| USP3 | ubiquitin specific peptidase 3 | -0.0205108 |
| SBF2 | SET binding factor 2 | -0.020248 |
| RBM25 | RNA binding motif protein 25 | -0.0199079 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0198629 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0196749 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0193555 |
| CDK8 | cyclin-dependent kinase 8 | -0.0193113 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0192074 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0191657 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0190724 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0185617 |
| NKTR | natural killer cell triggering receptor | -0.0185394 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0184785 |
| SKI | SKI proto-oncogene | -0.0184485 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0183661 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0183302 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0181001 |
| YEATS2 | YEATS domain containing 2 | -0.0180522 |
| MAP7 | microtubule-associated protein 7 | -0.0179712 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0179274 |
| FNDC3B | fibronectin type III domain containing 3B | -0.017831 |
| ZNF638 | zinc finger protein 638 | -0.0176367 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0176253 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0175692 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0175582 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0173944 |
| USP34 | ubiquitin specific peptidase 34 | -0.0172184 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0170151 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0170096 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0168547 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0168422 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0167285 |
| RPS2 | ribosomal protein S2 | -0.0164408 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0164389 |
| HYOU1 | hypoxia up-regulated 1 | -0.0162753 |
| SUCO | SUN domain containing ossification factor | -0.0162716 |
| METTL15 | methyltransferase like 15 | -0.0162372 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0162153 |
| MED13L | mediator complex subunit 13-like | -0.0160292 |
| TNPO1 | transportin 1 | -0.016026 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0158336 |
