| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.114798 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.110921 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.109852 |
| FAM13A | family with sequence similarity 13, member A | 0.102538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0833497 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0811891 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0693697 |
| CD109 | CD109 molecule | 0.0663102 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0656622 |
| GOLGA4 | golgin A4 | 0.0630246 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0606513 |
| NGLY1 | N-glycanase 1 | 0.055754 |
| FLNB | filamin B, beta | 0.054219 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0496191 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0484116 |
| LOX | lysyl oxidase | 0.0472151 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0464095 |
| PDE10A | phosphodiesterase 10A | 0.0455556 |
| ZNF148 | zinc finger protein 148 | 0.0453348 |
| SETD5 | SET domain containing 5 | 0.0438917 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.042385 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0419397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.04187 |
| ZNF292 | zinc finger protein 292 | 0.0418332 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0416964 |
| RUNX1 | runt-related transcription factor 1 | 0.04131 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0408762 |
| SPAG9 | sperm associated antigen 9 | 0.0408085 |
| MYOF | myoferlin | 0.0394303 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0393393 |
| PCBP3 | poly(rC) binding protein 3 | 0.0393306 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.037568 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0371762 |
| HELZ | helicase with zinc finger | 0.0358624 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0357868 |
| DST | dystonin | 0.0354923 |
| OGA | O-GlcNAcase | 0.0348135 |
| VEGFA | vascular endothelial growth factor A | 0.0347784 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.034496 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0343284 |
| SBF2 | SET binding factor 2 | 0.0342288 |
| ADM | adrenomedullin | 0.0338589 |
| INSIG2 | insulin induced gene 2 | 0.0336468 |
| ARRDC3 | arrestin domain containing 3 | 0.0320842 |
| TMF1 | TATA element modulatory factor 1 | 0.0319922 |
| YEATS2 | YEATS domain containing 2 | 0.0319302 |
| PCBP2 | poly(rC) binding protein 2 | 0.0318642 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0308518 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0308506 |
| SEPTIN9 | septin 9 | 0.0308014 |
| RBM39 | RNA binding motif protein 39 | 0.0307998 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0307337 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0303785 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0300886 |
| PTK2 | protein tyrosine kinase 2 | 0.0299704 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0295469 |
| TNS1 | tensin 1 | 0.0293276 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0291648 |
| RNF145 | ring finger protein 145 | 0.0291003 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0289194 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0284746 |
| FNIP1 | folliculin interacting protein 1 | 0.0280942 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0280031 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0276082 |
| COPA | coatomer protein complex, subunit alpha | 0.0272919 |
| SRP54 | signal recognition particle 54kDa | 0.0272061 |
| SMAD3 | SMAD family member 3 | 0.0271414 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0271351 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0265878 |
| NKTR | natural killer cell triggering receptor | 0.0265056 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.025854 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0255892 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0254917 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0253799 |
| ANXA2 | annexin A2 | 0.0253152 |
| LDHA | lactate dehydrogenase A | 0.0252741 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0251376 |
| COL5A1 | collagen, type V, alpha 1 | 0.0251278 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0245527 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0244293 |
| PRELID2 | PRELI domain containing 2 | 0.024142 |
| ZNF451 | zinc finger protein 451 | 0.0236921 |
| IRS2 | insulin receptor substrate 2 | 0.02365 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0234496 |
| TXNIP | thioredoxin interacting protein | 0.0234487 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0228214 |
| NAV2 | neuron navigator 2 | 0.0227577 |
| CD47 | CD47 molecule | 0.0225743 |
| MEF2A | myocyte enhancer factor 2A | 0.022329 |
| IGF2 | insulin-like growth factor 2 | 0.0222948 |
| BBX | bobby sox homolog (Drosophila) | 0.0221677 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0221361 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.021922 |
| RNF24 | ring finger protein 24 | 0.0218998 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0218622 |
| MYO1B | myosin IB | 0.0215682 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.021568 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0215145 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0212966 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0211453 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.210508 |
| HMGA2 | high mobility group AT-hook 2 | -0.164465 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.119648 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.115721 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109902 |
| TMSB10 | thymosin beta 10 | -0.106491 |
| VIM | vimentin | -0.102169 |
| EGR1 | early growth response 1 | -0.100743 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0913088 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0910269 |
| GLIS3 | GLIS family zinc finger 3 | -0.0882465 |
| VCL | vinculin | -0.0814019 |
| ACTG1 | actin gamma 1 | -0.0747258 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0729324 |
| AHNAK | AHNAK nucleoprotein | -0.0714023 |
| STC1 | stanniocalcin 1 | -0.0687493 |
| MT2A | metallothionein 2A | -0.0668376 |
| NAV1 | neuron navigator 1 | -0.0557808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0541327 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0532397 |
| CDH13 | cadherin 13 | -0.0510374 |
| CCND1 | cyclin D1 | -0.0508807 |
| CLMP | CXADR-like membrane protein | -0.0507752 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0507726 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0504893 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0481438 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0459008 |
| LAMB3 | laminin, beta 3 | -0.0451425 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.044334 |
| DUSP6 | dual specificity phosphatase 6 | -0.042653 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.04257 |
| ACTN1 | actinin, alpha 1 | -0.0414478 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0410043 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0408551 |
| ACTN4 | actinin, alpha 4 | -0.0407741 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0405297 |
| IER3 | immediate early response 3 | -0.0402355 |
| PLEC | plectin | -0.0390037 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0375456 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0364941 |
| RRBP1 | ribosome binding protein 1 | -0.0358513 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0347018 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331611 |
| CDCP1 | CUB domain containing protein 1 | -0.0328707 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0328567 |
| TUBB6 | tubulin, beta 6 class V | -0.0328072 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0307816 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0304569 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0300133 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0299505 |
| INHBA | inhibin, beta A | -0.0292157 |
| RPL35A | ribosomal protein L35a | -0.0288627 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.028537 |
| IL11 | interleukin 11 | -0.0284244 |
| IL1B | interleukin 1, beta | -0.0281724 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0276306 |
| OSMR | oncostatin M receptor | -0.0266932 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0265787 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0260311 |
| CLIC4 | chloride intracellular channel 4 | -0.0260006 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.025495 |
| CAVIN1 | caveolae associated protein 1 | -0.0251933 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0251283 |
| CD82 | CD82 molecule | -0.0251228 |
| FLNA | filamin A, alpha | -0.024799 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0246287 |
| TNNC1 | troponin C type 1 (slow) | -0.0246234 |
| PGK1 | phosphoglycerate kinase 1 | -0.0244122 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.024399 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0242322 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0241689 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0241415 |
| S100A10 | S100 calcium binding protein A10 | -0.0239163 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0237664 |
| RRM2 | ribonucleotide reductase M2 | -0.0233647 |
| SH2B3 | SH2B adaptor protein 3 | -0.023231 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0230633 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0230589 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0228781 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.022672 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0223881 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0218334 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0216624 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0214721 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0214369 |
| TPM4 | tropomyosin 4 | -0.0208763 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0208518 |
| RPS24 | ribosomal protein S24 | -0.0205819 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0195704 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0191307 |
| LAMA4 | laminin, alpha 4 | -0.0190044 |
| CAPRIN2 | caprin family member 2 | -0.0190013 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0189699 |
| NABP1 | nucleic acid binding protein 1 | -0.0189029 |
| NLK | nemo-like kinase | -0.0186311 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0182723 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0182186 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0182007 |
| PRSS23 | protease, serine, 23 | -0.0181793 |
| TOP1 | topoisomerase (DNA) I | -0.0181517 |
