| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.144639 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0784162 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.076829 |
| ATP13A3 | ATPase type 13A3 | 0.0556441 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0502918 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0451439 |
| SMAD3 | SMAD family member 3 | 0.0338609 |
| VEGFA | vascular endothelial growth factor A | 0.0335511 |
| SPAG9 | sperm associated antigen 9 | 0.0332976 |
| GOLGA4 | golgin A4 | 0.0327494 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0325265 |
| DST | dystonin | 0.0321564 |
| POSTN | periostin, osteoblast specific factor | 0.0317809 |
| PTK2 | protein tyrosine kinase 2 | 0.031175 |
| RBM39 | RNA binding motif protein 39 | 0.027839 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0273167 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0273013 |
| ARRDC3 | arrestin domain containing 3 | 0.0262342 |
| RASA2 | RAS p21 protein activator 2 | 0.0255497 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0243635 |
| SBF2 | SET binding factor 2 | 0.0239163 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0237324 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0229571 |
| COPA | coatomer protein complex, subunit alpha | 0.022671 |
| RNF145 | ring finger protein 145 | 0.0216884 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0214245 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0208929 |
| MLF1 | myeloid leukemia factor 1 | 0.0208311 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0207941 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0206863 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0204985 |
| FAT1 | FAT atypical cadherin 1 | 0.0202702 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0202002 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0200792 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0199013 |
| KIF1B | kinesin family member 1B | 0.0194956 |
| CCNL1 | cyclin L1 | 0.0192849 |
| AFAP1 | actin filament associated protein 1 | 0.0192216 |
| ZNF148 | zinc finger protein 148 | 0.0192128 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0189632 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0189529 |
| FOXJ3 | forkhead box J3 | 0.018862 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0187147 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0187039 |
| SRPK2 | SRSF protein kinase 2 | 0.0186625 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0185502 |
| CADM1 | cell adhesion molecule 1 | 0.0185437 |
| NBAS | neuroblastoma amplified sequence | 0.0182259 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0181556 |
| TFG | TRK-fused gene | 0.018145 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0179987 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0179852 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0178912 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0178258 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.017778 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0177283 |
| CLINT1 | clathrin interactor 1 | 0.0175356 |
| TMF1 | TATA element modulatory factor 1 | 0.0173678 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0172918 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0171439 |
| USP3 | ubiquitin specific peptidase 3 | 0.0170698 |
| PCBP2 | poly(rC) binding protein 2 | 0.0170173 |
| TMEM39A | transmembrane protein 39A | 0.0169054 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0167758 |
| QKI | QKI, KH domain containing, RNA binding | 0.0167735 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0167702 |
| MED13L | mediator complex subunit 13-like | 0.016449 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0164377 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0163941 |
| PCM1 | pericentriolar material 1 | 0.0163928 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0162671 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0162633 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0161806 |
| RLF | rearranged L-myc fusion | 0.0161799 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0159121 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0158687 |
| SUCO | SUN domain containing ossification factor | 0.0156486 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0155909 |
| SLMAP | sarcolemma associated protein | 0.0155293 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0154205 |
| HMGA2 | high mobility group AT-hook 2 | 0.015274 |
| EVI5 | ecotropic viral integration site 5 | 0.0151426 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0151242 |
| ARF4 | ADP-ribosylation factor 4 | 0.015017 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0149549 |
| USP24 | ubiquitin specific peptidase 24 | 0.0148612 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0147536 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0147379 |
| NOTCH2 | notch 2 | 0.0146751 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0143357 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0142358 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0141029 |
| NKTR | natural killer cell triggering receptor | 0.0140722 |
| MSN | moesin | 0.0140709 |
| PHIP | pleckstrin homology domain interacting protein | 0.0139897 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0139486 |
| TXNRD1 | thioredoxin reductase 1 | 0.013948 |
| LAMB1 | laminin, beta 1 | 0.0139312 |
| JMJD1C | jumonji domain containing 1C | 0.0138759 |
| FNBP1L | formin binding protein 1-like | 0.0137562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167924 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152365 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134163 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.124455 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11457 |
| MT2A | metallothionein 2A | -0.100837 |
| TMSB10 | thymosin beta 10 | -0.0977798 |
| NDRG1 | N-myc downstream regulated 1 | -0.0939852 |
| IER3 | immediate early response 3 | -0.0797078 |
| ENO1 | enolase 1, (alpha) | -0.0749521 |
| CDH13 | cadherin 13 | -0.074794 |
| VIM | vimentin | -0.0729893 |
| COL1A1 | collagen, type I, alpha 1 | -0.0718779 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0537777 |
| RPL35A | ribosomal protein L35a | -0.0525203 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0507606 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0507073 |
| HLA-B | major histocompatibility complex, class I, B | -0.0495128 |
| RPS8 | ribosomal protein S8 | -0.0494775 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0475605 |
| CALR | calreticulin | -0.046447 |
| FTL | ferritin, light polypeptide | -0.0448848 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0444788 |
| STC1 | stanniocalcin 1 | -0.0443143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.043365 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0430137 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0413369 |
| COL1A2 | collagen, type I, alpha 2 | -0.0405386 |
| S100A9 | S100 calcium binding protein A9 | -0.0384355 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0378332 |
| FBN1 | fibrillin 1 | -0.0378286 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0370141 |
| AHNAK | AHNAK nucleoprotein | -0.0355904 |
| RPS6 | ribosomal protein S6 | -0.0352604 |
| INHBA | inhibin, beta A | -0.0341298 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0327683 |
| RPL30 | ribosomal protein L30 | -0.0327013 |
| ACTG1 | actin gamma 1 | -0.0318273 |
| OSMR | oncostatin M receptor | -0.0315474 |
| VCL | vinculin | -0.0315141 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0312053 |
| RPL23 | ribosomal protein L23 | -0.0310609 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0308104 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0306256 |
| RPL26 | ribosomal protein L26 | -0.030094 |
| CANX | calnexin | -0.0294123 |
| TPM4 | tropomyosin 4 | -0.0292706 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0292343 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0290982 |
| S100A6 | S100 calcium binding protein A6 | -0.028868 |
| RPL34 | ribosomal protein L34 | -0.0278581 |
| PDLIM5 | PDZ and LIM domain 5 | -0.027748 |
| ASPH | aspartate beta-hydroxylase | -0.0269485 |
| COL5A1 | collagen, type V, alpha 1 | -0.0268785 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0266693 |
| S100A10 | S100 calcium binding protein A10 | -0.0266109 |
| RPS12 | ribosomal protein S12 | -0.0265622 |
| RPLP1 | ribosomal protein, large, P1 | -0.0264754 |
| RPL19 | ribosomal protein L19 | -0.0259805 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0257975 |
| SQSTM1 | sequestosome 1 | -0.0256632 |
| RPL28 | ribosomal protein L28 | -0.0255212 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0254936 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0251007 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0249309 |
| RPL37A | ribosomal protein L37a | -0.0249001 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0248495 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0247786 |
| IL6 | interleukin 6 | -0.0243345 |
| RACK1 | receptor for activated C kinase 1 | -0.024296 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0241976 |
| RPS20 | ribosomal protein S20 | -0.024004 |
| PTMA | prothymosin, alpha | -0.0240002 |
| RPL12 | ribosomal protein L12 | -0.0232579 |
| UBC | ubiquitin C | -0.0231338 |
| TMSB4X | thymosin beta 4, X-linked | -0.0230279 |
| CD44 | CD44 molecule (Indian blood group) | -0.0229235 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0226543 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225465 |
| HLA-A | major histocompatibility complex, class I, A | -0.0220218 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0219228 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0219214 |
| RPS19 | ribosomal protein S19 | -0.0217197 |
| B2M | beta-2-microglobulin | -0.0216598 |
| RPS3 | ribosomal protein S3 | -0.0214272 |
| RPS25 | ribosomal protein S25 | -0.0213581 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0212223 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0211737 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0209562 |
| RPS11 | ribosomal protein S11 | -0.0208656 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0207397 |
| LOXL2 | lysyl oxidase-like 2 | -0.0206134 |
| CLMP | CXADR-like membrane protein | -0.0204286 |
| RPL8 | ribosomal protein L8 | -0.0203601 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0200178 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0199691 |
| RPL36 | ribosomal protein L36 | -0.0198375 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0197949 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0197195 |
| MTDH | metadherin | -0.0196921 |
