| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.101625 |
| FTL | ferritin, light polypeptide | 0.0911058 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0906289 |
| PTMA | prothymosin, alpha | 0.0815613 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0800255 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0774238 |
| B2M | beta-2-microglobulin | 0.0719071 |
| TXNRD1 | thioredoxin reductase 1 | 0.0713905 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0650022 |
| TMC5 | transmembrane channel-like 5 | 0.063363 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0611064 |
| PTK2 | protein tyrosine kinase 2 | 0.0601788 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0589855 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.057664 |
| EZR | ezrin | 0.0574131 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0566416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0564736 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0552552 |
| LYZ | lysozyme | 0.054745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0544915 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0519635 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0511486 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0499445 |
| STK24 | serine/threonine kinase 24 | 0.0488692 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0455334 |
| RPS6 | ribosomal protein S6 | 0.0454219 |
| CD2AP | CD2-associated protein | 0.0429596 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0425512 |
| DGKH | diacylglycerol kinase, eta | 0.0408684 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0404804 |
| KRT18 | keratin 18, type I | 0.0402292 |
| LDHA | lactate dehydrogenase A | 0.0400072 |
| RPS3 | ribosomal protein S3 | 0.0399412 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0378797 |
| PDZD8 | PDZ domain containing 8 | 0.0378596 |
| FOXP1 | forkhead box P1 | 0.0378581 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0367648 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0365017 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0361504 |
| DNM2 | dynamin 2 | 0.0359617 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0359554 |
| TMEM45B | transmembrane protein 45B | 0.0356556 |
| FNBP4 | formin binding protein 4 | 0.0351931 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0350538 |
| MUC13 | mucin 13, cell surface associated | 0.0350194 |
| KRT20 | keratin 20, type I | 0.0349623 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0349062 |
| ERBIN | erbb2 interacting protein | 0.0347308 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.034467 |
| JMJD1C | jumonji domain containing 1C | 0.0340648 |
| BPTF | bromodomain PHD finger transcription factor | 0.033914 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0336891 |
| MKI67 | marker of proliferation Ki-67 | 0.0322959 |
| ETV6 | ets variant 6 | 0.0317082 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0315659 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0315579 |
| SEPTIN9 | septin 9 | 0.0315471 |
| S100A6 | S100 calcium binding protein A6 | 0.0313971 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0308269 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0302484 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0301476 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0293721 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0288544 |
| RPS13 | ribosomal protein S13 | 0.0287281 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0286487 |
| FRY | furry homolog (Drosophila) | 0.0286486 |
| NDRG1 | N-myc downstream regulated 1 | 0.02849 |
| KRT19 | keratin 19, type I | 0.027912 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0278505 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0276794 |
| TJP1 | tight junction protein 1 | 0.0275199 |
| PGK1 | phosphoglycerate kinase 1 | 0.0275164 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0275001 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0271826 |
| KIAA0232 | KIAA0232 | 0.0270529 |
| CLDN4 | claudin 4 | 0.026859 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0268115 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0267814 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0267288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0264942 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0263919 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0263335 |
| EPCAM | epithelial cell adhesion molecule | 0.0262434 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0262394 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.025963 |
| WWC1 | WW and C2 domain containing 1 | 0.0258977 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.025749 |
| NF1 | neurofibromin 1 | 0.0254459 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0253774 |
| MYO6 | myosin VI | 0.0252723 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.025026 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0248171 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0248051 |
| ANXA4 | annexin A4 | 0.0246656 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0245438 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0243642 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.024304 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0242356 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0239435 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0236189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0999775 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0935688 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0884611 |
| INTS6 | integrator complex subunit 6 | -0.0749012 |
| SMAD3 | SMAD family member 3 | -0.0587773 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0546306 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0462318 |
| LAMA4 | laminin, alpha 4 | -0.0461429 |
| AHNAK | AHNAK nucleoprotein | -0.0430321 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0405011 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0404502 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0394899 |
| VCL | vinculin | -0.0368762 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0356535 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0345688 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0340068 |
| MCL1 | myeloid cell leukemia 1 | -0.0328004 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0322726 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.031894 |
| AGR2 | anterior gradient 2 | -0.0318649 |
| TUFT1 | tuftelin 1 | -0.0280422 |
| PRELID2 | PRELI domain containing 2 | -0.0260388 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0257708 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0250265 |
| PRR5L | proline rich 5 like | -0.0246632 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0239293 |
| SDCBP | syndecan binding protein (syntenin) | -0.0233929 |
| SERTAD2 | SERTA domain containing 2 | -0.0231584 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0225843 |
| CTBP2 | C-terminal binding protein 2 | -0.0224385 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0210213 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0206304 |
| NABP1 | nucleic acid binding protein 1 | -0.0205525 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0203091 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0200557 |
| CAPN8 | calpain 8 | -0.019943 |
| MORF4L2 | mortality factor 4 like 2 | -0.0198284 |
| RTN3 | reticulon 3 | -0.0196329 |
| FBXO32 | F-box protein 32 | -0.0195705 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0194236 |
| RPL23 | ribosomal protein L23 | -0.0192326 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0187203 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0186126 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0185617 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0185306 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0184958 |
| PRKCA | protein kinase C, alpha | -0.0184641 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.018352 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0175959 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0175492 |
| RYBP | RING1 and YY1 binding protein | -0.0172026 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0161029 |
| CCNYL1 | cyclin Y-like 1 | -0.0159472 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0156461 |
| HMGB1 | high mobility group box 1 | -0.015594 |
| POF1B | premature ovarian failure, 1B | -0.0154221 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.015192 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0151421 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0149227 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0148797 |
| HOMER1 | homer scaffolding protein 1 | -0.0148209 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0147209 |
| PLEC | plectin | -0.0146668 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0146223 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0145986 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0143497 |
| LNX2 | ligand of numb-protein X 2 | -0.0143296 |
| RASEF | RAS and EF-hand domain containing | -0.0142337 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0141969 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0140931 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0140793 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0138399 |
| HBP1 | HMG-box transcription factor 1 | -0.0137139 |
| SKI | SKI proto-oncogene | -0.0136369 |
| CANX | calnexin | -0.0133965 |
| HM13 | histocompatibility (minor) 13 | -0.0133217 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0132581 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0132279 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0130575 |
| SEC24D | SEC24 family member D | -0.01304 |
| FLNA | filamin A, alpha | -0.0129857 |
| IRS2 | insulin receptor substrate 2 | -0.0127406 |
| RPL4 | ribosomal protein L4 | -0.0127245 |
| STK17A | serine/threonine kinase 17a | -0.0126474 |
| TMEM65 | transmembrane protein 65 | -0.0126132 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0125764 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0123174 |
| ADD1 | adducin 1 (alpha) | -0.0122493 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0121071 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.012012 |
| TFRC | transferrin receptor | -0.0120052 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0117919 |
| TLE4 | transducin-like enhancer of split 4 | -0.0116906 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0114869 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0114183 |
| KRT8 | keratin 8, type II | -0.0114183 |
| RCOR1 | REST corepressor 1 | -0.0112878 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0112668 |
| HYOU1 | hypoxia up-regulated 1 | -0.0111018 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0110915 |
