| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.120246 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.119745 |
| DPYD | dihydropyrimidine dehydrogenase | 0.103311 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0728436 |
| MTSS1 | metastasis suppressor 1 | 0.0683559 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0675715 |
| MSN | moesin | 0.0659796 |
| LMO7 | LIM domain 7 | 0.0643547 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0630767 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0602 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0573938 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0561353 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0557463 |
| SULF1 | sulfatase 1 | 0.0552964 |
| RASAL2 | RAS protein activator like 2 | 0.0541069 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0511978 |
| PODXL | podocalyxin-like | 0.0498189 |
| FOXO1 | forkhead box O1 | 0.0497573 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0493801 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.047535 |
| ITGA6 | integrin, alpha 6 | 0.0441634 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0434796 |
| RAI14 | retinoic acid induced 14 | 0.0426992 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0423892 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0423127 |
| EGFR | epidermal growth factor receptor | 0.0409635 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0409566 |
| EFNA5 | ephrin-A5 | 0.0400416 |
| UTRN | utrophin | 0.0368903 |
| RAD51B | RAD51 paralog B | 0.0367065 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0366655 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0359974 |
| AMOTL1 | angiomotin like 1 | 0.0358616 |
| MECOM | MDS1 and EVI1 complex locus | 0.0345887 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.034494 |
| LAMC2 | laminin, gamma 2 | 0.0339328 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0336927 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0336868 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0328868 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0327795 |
| EXOC4 | exocyst complex component 4 | 0.0326978 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0322623 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0320069 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0315919 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.031147 |
| DGKH | diacylglycerol kinase, eta | 0.0305732 |
| CDK6 | cyclin-dependent kinase 6 | 0.0303097 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0298805 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0297176 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0294651 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0293495 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0293426 |
| SMYD3 | SET and MYND domain containing 3 | 0.028692 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0281549 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0276549 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0274248 |
| RIN2 | Ras and Rab interactor 2 | 0.0272918 |
| HDAC9 | histone deacetylase 9 | 0.0271471 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0267677 |
| RCOR1 | REST corepressor 1 | 0.0265617 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.026299 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0259798 |
| RNF217 | ring finger protein 217 | 0.0259019 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0258182 |
| NRG1 | neuregulin 1 | 0.025623 |
| BLCAP | bladder cancer associated protein | 0.0252527 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0250725 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0248221 |
| TNS3 | tensin 3 | 0.0247732 |
| PTK2 | protein tyrosine kinase 2 | 0.0247116 |
| CAPRIN2 | caprin family member 2 | 0.024322 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0242601 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0241925 |
| MYO10 | myosin X | 0.0241758 |
| HMGA2 | high mobility group AT-hook 2 | 0.0241615 |
| SETX | senataxin | 0.0240395 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0239801 |
| OSMR | oncostatin M receptor | 0.0238254 |
| PCDH1 | protocadherin 1 | 0.0234167 |
| PTHLH | parathyroid hormone-like hormone | 0.0233894 |
| DST | dystonin | 0.0233552 |
| MCL1 | myeloid cell leukemia 1 | 0.0232968 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0231064 |
| BCL2L1 | BCL2-like 1 | 0.0223993 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0223649 |
| TGM2 | transglutaminase 2 | 0.0223209 |
| ATXN1 | ataxin 1 | 0.0221297 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0221036 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.02187 |
| DOK5 | docking protein 5 | 0.0218515 |
| JMJD1C | jumonji domain containing 1C | 0.0218031 |
| PLS3 | plastin 3 | 0.0214794 |
| TPM3 | tropomyosin 3 | 0.0213398 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0211591 |
| PALLD | palladin, cytoskeletal associated protein | 0.0211484 |
| LUZP1 | leucine zipper protein 1 | 0.021028 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0209526 |
| EXOC6B | exocyst complex component 6B | 0.0209109 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209097 |
| PRELID2 | PRELI domain containing 2 | 0.0208634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207244 |
| TMSB10 | thymosin beta 10 | -0.118725 |
| PTMA | prothymosin, alpha | -0.111726 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102007 |
| S100A10 | S100 calcium binding protein A10 | -0.095715 |
| RPS21 | ribosomal protein S21 | -0.0931168 |
| MT2A | metallothionein 2A | -0.0900812 |
| RPLP1 | ribosomal protein, large, P1 | -0.0810484 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0809087 |
| RPS6 | ribosomal protein S6 | -0.0804297 |
| RPS8 | ribosomal protein S8 | -0.079497 |
| TMSB4X | thymosin beta 4, X-linked | -0.07642 |
| GNAS | GNAS complex locus | -0.076128 |
| LMNA | lamin A/C | -0.0753614 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0704836 |
| RPL11 | ribosomal protein L11 | -0.0674241 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0668967 |
| KRT17 | keratin 17, type I | -0.0665743 |
| RPLP2 | ribosomal protein, large, P2 | -0.066407 |
| PGK1 | phosphoglycerate kinase 1 | -0.0615654 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0591394 |
| RPS19 | ribosomal protein S19 | -0.0571074 |
| H1-0 | H1.0 linker histone | -0.0568733 |
| B2M | beta-2-microglobulin | -0.0546181 |
| RPS24 | ribosomal protein S24 | -0.0533408 |
| RPL8 | ribosomal protein L8 | -0.0521861 |
| RPS13 | ribosomal protein S13 | -0.0512829 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0495571 |
| RPL23 | ribosomal protein L23 | -0.04881 |
| RPL12 | ribosomal protein L12 | -0.0480068 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0477387 |
| RPL34 | ribosomal protein L34 | -0.047267 |
| RPL35A | ribosomal protein L35a | -0.0449538 |
| RPL37 | ribosomal protein L37 | -0.0445989 |
| S100A6 | S100 calcium binding protein A6 | -0.0438772 |
| S100A2 | S100 calcium binding protein A2 | -0.0438174 |
| STC1 | stanniocalcin 1 | -0.0424099 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0422941 |
| RPL19 | ribosomal protein L19 | -0.0422511 |
| RPS3 | ribosomal protein S3 | -0.0420516 |
| RPL27A | ribosomal protein L27a | -0.0418882 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0416029 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0413634 |
| RPS25 | ribosomal protein S25 | -0.0411365 |
| S100A9 | S100 calcium binding protein A9 | -0.0408116 |
| FTL | ferritin, light polypeptide | -0.0407017 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0390313 |
| MT1X | metallothionein 1X | -0.0390037 |
| RPLP0 | ribosomal protein, large, P0 | -0.0387248 |
| RACK1 | receptor for activated C kinase 1 | -0.0386554 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0386529 |
| HLA-B | major histocompatibility complex, class I, B | -0.0385714 |
| ENO1 | enolase 1, (alpha) | -0.0385491 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0384613 |
| OGA | O-GlcNAcase | -0.0383036 |
| RLF | rearranged L-myc fusion | -0.0379287 |
| RPS27A | ribosomal protein S27a | -0.0378355 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0372423 |
| RPL26 | ribosomal protein L26 | -0.0369626 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0364708 |
| RPS20 | ribosomal protein S20 | -0.0352937 |
| RPL30 | ribosomal protein L30 | -0.0352176 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0349864 |
| RPL5 | ribosomal protein L5 | -0.0345359 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0337514 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0334218 |
| RPS12 | ribosomal protein S12 | -0.0333786 |
| RPL31 | ribosomal protein L31 | -0.0330626 |
| GOLGA4 | golgin A4 | -0.0329517 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0327481 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0327119 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0325953 |
| CANX | calnexin | -0.0324925 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0321427 |
| YBX1 | Y box binding protein 1 | -0.032141 |
| IER3 | immediate early response 3 | -0.0320962 |
| MORF4L2 | mortality factor 4 like 2 | -0.0320318 |
| RPS14 | ribosomal protein S14 | -0.0317587 |
| RPL32 | ribosomal protein L32 | -0.0316904 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0313736 |
| ARF1 | ADP-ribosylation factor 1 | -0.0312139 |
| MATR3 | matrin 3 | -0.0311782 |
| AHNAK | AHNAK nucleoprotein | -0.031047 |
| CAVIN1 | caveolae associated protein 1 | -0.0309786 |
| RPL28 | ribosomal protein L28 | -0.0305721 |
| RPL35 | ribosomal protein L35 | -0.0304237 |
| RPL7A | ribosomal protein L7a | -0.0302899 |
| ANXA2 | annexin A2 | -0.0301173 |
| RPL36 | ribosomal protein L36 | -0.030109 |
| RPS11 | ribosomal protein S11 | -0.0300505 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0299704 |
| SQSTM1 | sequestosome 1 | -0.0299102 |
| RPS27 | ribosomal protein S27 | -0.0298178 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0297841 |
| ANXA1 | annexin A1 | -0.0297079 |
| RPS29 | ribosomal protein S29 | -0.0296555 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02914 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0291263 |
| RPS16 | ribosomal protein S16 | -0.0291258 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0290807 |