| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0490841 |
| TXNRD1 | thioredoxin reductase 1 | 0.0479802 |
| HDAC9 | histone deacetylase 9 | 0.0462543 |
| DST | dystonin | 0.0442229 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0392487 |
| USP34 | ubiquitin specific peptidase 34 | 0.0371753 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0353352 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337548 |
| RND3 | Rho family GTPase 3 | 0.0306528 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0302455 |
| ERBIN | erbb2 interacting protein | 0.0297597 |
| SMAD3 | SMAD family member 3 | 0.0287604 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0284294 |
| RUNX1 | runt-related transcription factor 1 | 0.0281245 |
| CD109 | CD109 molecule | 0.0267128 |
| EMP1 | epithelial membrane protein 1 | 0.0264036 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0254827 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245886 |
| CD44 | CD44 molecule (Indian blood group) | 0.0243401 |
| JMJD1C | jumonji domain containing 1C | 0.0229902 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0217482 |
| FRMD6 | FERM domain containing 6 | 0.0215818 |
| STC1 | stanniocalcin 1 | 0.0213714 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0205203 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0204047 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.020296 |
| YBX3 | Y box binding protein 3 | 0.0196835 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0195988 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.019321 |
| EXOC6B | exocyst complex component 6B | 0.0192743 |
| ATP13A3 | ATPase type 13A3 | 0.0191389 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0190023 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.018866 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0184461 |
| BPTF | bromodomain PHD finger transcription factor | 0.0183738 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183054 |
| TXNIP | thioredoxin interacting protein | 0.0182339 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0174638 |
| NF1 | neurofibromin 1 | 0.0170839 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0170682 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0170305 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.016977 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0168449 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0168339 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0165549 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0163826 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0162582 |
| CENPF | centromere protein F, 350/400kDa | 0.0162354 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0162171 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0162053 |
| KLF12 | Kruppel-like factor 12 | 0.016054 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.015803 |
| PAPOLA | poly(A) polymerase alpha | 0.0157422 |
| ZNF638 | zinc finger protein 638 | 0.0156638 |
| RASAL2 | RAS protein activator like 2 | 0.0156513 |
| GPHN | gephyrin | 0.0154747 |
| FNIP1 | folliculin interacting protein 1 | 0.0154693 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0152962 |
| ATM | ATM serine/threonine kinase | 0.0152062 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0151515 |
| NRP2 | neuropilin 2 | 0.0148329 |
| MCL1 | myeloid cell leukemia 1 | 0.0148312 |
| BRD2 | bromodomain containing 2 | 0.0147979 |
| ANXA1 | annexin A1 | 0.0147934 |
| JUN | jun proto-oncogene | 0.0147435 |
| NCKAP1 | NCK-associated protein 1 | 0.0146407 |
| ECT2 | epithelial cell transforming 2 | 0.0146205 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0146155 |
| ANO6 | anoctamin 6 | 0.0145559 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0145119 |
| NUP58 | nucleoporin 58 | 0.0144674 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0144395 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0144371 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0144338 |
| DTNA | dystrobrevin, alpha | 0.0143997 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0143932 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0143843 |
| NBEA | neurobeachin | 0.0143495 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0143117 |
| PEG10 | paternally expressed 10 | 0.0142044 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0142004 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.014079 |
| TMF1 | TATA element modulatory factor 1 | 0.0139788 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0139087 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0136154 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0136048 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0135761 |
| TNPO1 | transportin 1 | 0.0135198 |
| NAV3 | neuron navigator 3 | 0.0134701 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0134026 |
| ARRDC3 | arrestin domain containing 3 | 0.0133714 |
| PAX3 | paired box 3 | 0.0131241 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0130902 |
| CDK19 | cyclin-dependent kinase 19 | 0.0129884 |
| QSER1 | glutamine and serine rich 1 | 0.0129351 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0129333 |
| SPAG9 | sperm associated antigen 9 | 0.0128752 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0127198 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0126409 |
| SMYD3 | SET and MYND domain containing 3 | 0.0125241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.203083 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.181527 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168589 |
| RPS6 | ribosomal protein S6 | -0.120995 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117994 |
| TMSB10 | thymosin beta 10 | -0.100018 |
| RPL23 | ribosomal protein L23 | -0.0801439 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.078577 |
| PTMA | prothymosin, alpha | -0.0701011 |
| ACTG1 | actin gamma 1 | -0.0695662 |
| RPLP1 | ribosomal protein, large, P1 | -0.058341 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.055642 |
| RPS8 | ribosomal protein S8 | -0.0531355 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0526431 |
| CDH13 | cadherin 13 | -0.0500728 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0480475 |
| RPS12 | ribosomal protein S12 | -0.0468541 |
| RPL12 | ribosomal protein L12 | -0.0466247 |
| LSAMP | limbic system-associated membrane protein | -0.0464601 |
| NAV1 | neuron navigator 1 | -0.0450486 |
| RPL37A | ribosomal protein L37a | -0.0439779 |
| EFNA5 | ephrin-A5 | -0.0435523 |
| RPL35A | ribosomal protein L35a | -0.0423969 |
| RPS19 | ribosomal protein S19 | -0.042233 |
| FTL | ferritin, light polypeptide | -0.0399506 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.039436 |
| KIAA1549L | KIAA1549-like | -0.0392168 |
| TPM4 | tropomyosin 4 | -0.0385369 |
| RPS3 | ribosomal protein S3 | -0.0384634 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0370276 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0369159 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0357193 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0354968 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0353728 |
| RPS2 | ribosomal protein S2 | -0.0353482 |
| RPLP2 | ribosomal protein, large, P2 | -0.0347743 |
| RPS20 | ribosomal protein S20 | -0.0343786 |
| AHNAK | AHNAK nucleoprotein | -0.0340426 |
| RPL26 | ribosomal protein L26 | -0.0335496 |
| RPL34 | ribosomal protein L34 | -0.032563 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0315373 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302242 |
| RPL8 | ribosomal protein L8 | -0.0300276 |
| RPL13A | ribosomal protein L13a | -0.0294204 |
| RPL19 | ribosomal protein L19 | -0.0290959 |
| RPS25 | ribosomal protein S25 | -0.0287241 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0282105 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.027587 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0273615 |
| KIAA1217 | KIAA1217 | -0.0269604 |
| GPC6 | glypican 6 | -0.0264888 |
| RPS24 | ribosomal protein S24 | -0.0264707 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0259326 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0254814 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0252715 |
| ZNF804A | zinc finger protein 804A | -0.024881 |
| RPL30 | ribosomal protein L30 | -0.0244829 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0244267 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0243733 |
| RPS23 | ribosomal protein S23 | -0.0243406 |
| RPL11 | ribosomal protein L11 | -0.0242866 |
| RPS17 | ribosomal protein S17 | -0.0242827 |
| RPL5 | ribosomal protein L5 | -0.0241449 |
| RPS27A | ribosomal protein S27a | -0.0239882 |
| RPS29 | ribosomal protein S29 | -0.0235518 |
| RPS21 | ribosomal protein S21 | -0.0234904 |
| RPL27 | ribosomal protein L27 | -0.0234443 |
| PTK2 | protein tyrosine kinase 2 | -0.0231415 |
| TPI1 | triosephosphate isomerase 1 | -0.0230387 |
| RPS14 | ribosomal protein S14 | -0.0230065 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0229086 |
| RPS13 | ribosomal protein S13 | -0.022782 |
| CALD1 | caldesmon 1 | -0.022446 |
| RPL36 | ribosomal protein L36 | -0.0223128 |
| RPL37 | ribosomal protein L37 | -0.0222302 |
| RPS4X | ribosomal protein S4, X-linked | -0.0217996 |
| RPL31 | ribosomal protein L31 | -0.021741 |
| GNAS | GNAS complex locus | -0.0215873 |
| RPL9 | ribosomal protein L9 | -0.0215678 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0215532 |
| RACK1 | receptor for activated C kinase 1 | -0.0213765 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0207169 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0205992 |
| YBX1 | Y box binding protein 1 | -0.0203689 |
| ZNF292 | zinc finger protein 292 | -0.0202779 |
| RPL38 | ribosomal protein L38 | -0.0202765 |
| RPL35 | ribosomal protein L35 | -0.0201796 |
| MYO10 | myosin X | -0.0200496 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.019901 |
| RPL7 | ribosomal protein L7 | -0.0195967 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0195902 |
| VCL | vinculin | -0.019376 |
| LDHA | lactate dehydrogenase A | -0.0192654 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0191702 |
| RPL28 | ribosomal protein L28 | -0.018971 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0184858 |
| RPL32 | ribosomal protein L32 | -0.0184632 |
| RPS16 | ribosomal protein S16 | -0.0183253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0177976 |
| PGK1 | phosphoglycerate kinase 1 | -0.0177582 |
