| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0821372 |
| PCBP2 | poly(rC) binding protein 2 | 0.0629018 |
| PRELID2 | PRELI domain containing 2 | 0.0601466 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0590026 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0586889 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.055961 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.055092 |
| RNF145 | ring finger protein 145 | 0.0525916 |
| MUC13 | mucin 13, cell surface associated | 0.0500378 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0468401 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044194 |
| RAD51B | RAD51 paralog B | 0.0440417 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0433247 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0430222 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0421223 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420516 |
| GOLGA4 | golgin A4 | 0.0411202 |
| PTEN | phosphatase and tensin homolog | 0.041083 |
| SLK | STE20-like kinase | 0.0387132 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0377042 |
| CDK19 | cyclin-dependent kinase 19 | 0.0353108 |
| RPL21 | ribosomal protein L21 | 0.0352942 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0350568 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0348149 |
| KIF16B | kinesin family member 16B | 0.0343479 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0340931 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0329359 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0320563 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0320542 |
| RPL3 | ribosomal protein L3 | 0.0312553 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0310277 |
| ZNF292 | zinc finger protein 292 | 0.0309944 |
| PNN | pinin, desmosome associated protein | 0.0308137 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0302314 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0300268 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0297123 |
| PDE8A | phosphodiesterase 8A | 0.0295072 |
| CENPF | centromere protein F, 350/400kDa | 0.0293843 |
| LIMA1 | LIM domain and actin binding 1 | 0.0293228 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0289057 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0287953 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0287492 |
| FOXO1 | forkhead box O1 | 0.0282697 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0282308 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0278549 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0275627 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0268598 |
| ANXA11 | annexin A11 | 0.0265715 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0264188 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264102 |
| LDHA | lactate dehydrogenase A | 0.0262666 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0258393 |
| ITGA6 | integrin, alpha 6 | 0.0258047 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0254212 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0253668 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0252507 |
| ABHD17C | abhydrolase domain containing 17C | 0.0250406 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.024978 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0241966 |
| PTK2 | protein tyrosine kinase 2 | 0.0241441 |
| ATP10B | ATPase, class V, type 10B | 0.0241093 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0238172 |
| PKP2 | plakophilin 2 | 0.0238097 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0232876 |
| TPM3 | tropomyosin 3 | 0.0231257 |
| NRDC | nardilysin convertase | 0.0231051 |
| OPTN | optineurin | 0.0231018 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0230928 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0228987 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0228503 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0227753 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0222486 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0220144 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0218548 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0218331 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0216774 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0216488 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0216401 |
| EP400 | E1A binding protein p400 | 0.0216344 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0215886 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.021485 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214791 |
| CCNL1 | cyclin L1 | 0.0213776 |
| NCKAP1 | NCK-associated protein 1 | 0.0213746 |
| CALB1 | calbindin 1, 28kDa | 0.021252 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0212473 |
| SET | SET nuclear proto-oncogene | 0.0208966 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0208065 |
| ZNF148 | zinc finger protein 148 | 0.0205853 |
| UBE3A | ubiquitin protein ligase E3A | 0.0205561 |
| NKTR | natural killer cell triggering receptor | 0.020556 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0204294 |
| NUP58 | nucleoporin 58 | 0.0203605 |
| UBN2 | ubinuclein 2 | 0.0203328 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0202357 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0202263 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0202044 |
| BBX | bobby sox homolog (Drosophila) | 0.020164 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.020162 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0201471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.166726 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165608 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.16164 |
| RPLP1 | ribosomal protein, large, P1 | -0.135939 |
| LMO7 | LIM domain 7 | -0.126151 |
| ACTG1 | actin gamma 1 | -0.108286 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104968 |
| TMSB10 | thymosin beta 10 | -0.0926217 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0892335 |
| RPL4 | ribosomal protein L4 | -0.0777587 |
| RPLP0 | ribosomal protein, large, P0 | -0.0722642 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0665146 |
| RPS24 | ribosomal protein S24 | -0.0645642 |
| CANX | calnexin | -0.0599934 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0589942 |
| HDLBP | high density lipoprotein binding protein | -0.0550643 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0518033 |
| AHNAK | AHNAK nucleoprotein | -0.0510814 |
| RPL34 | ribosomal protein L34 | -0.0507363 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0503537 |
| LAMB3 | laminin, beta 3 | -0.0499734 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0497076 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0495366 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0490869 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0484447 |
| RPL35A | ribosomal protein L35a | -0.0481632 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0480504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.046634 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0459471 |
| MSI2 | musashi RNA-binding protein 2 | -0.0453234 |
| LAMA4 | laminin, alpha 4 | -0.0449011 |
| SQSTM1 | sequestosome 1 | -0.0444827 |
| IER3 | immediate early response 3 | -0.0436812 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0428872 |
| MYOF | myoferlin | -0.0427421 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0421972 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0421821 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0409321 |
| SERINC5 | serine incorporator 5 | -0.0407873 |
| RRBP1 | ribosome binding protein 1 | -0.0406454 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0406191 |
| RPS27A | ribosomal protein S27a | -0.0404799 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0396671 |
| VCL | vinculin | -0.0387889 |
| RPL19 | ribosomal protein L19 | -0.0387269 |
| S100A10 | S100 calcium binding protein A10 | -0.0384935 |
| RPL27A | ribosomal protein L27a | -0.038289 |
| KRT18 | keratin 18, type I | -0.0381182 |
| RPL12 | ribosomal protein L12 | -0.037596 |
| ANXA2 | annexin A2 | -0.0370989 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0368357 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0362628 |
| GDF15 | growth differentiation factor 15 | -0.036255 |
| SP100 | SP100 nuclear antigen | -0.0357528 |
| AGR2 | anterior gradient 2 | -0.0353854 |
| RPS25 | ribosomal protein S25 | -0.0350144 |
| RPLP2 | ribosomal protein, large, P2 | -0.0345787 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0341199 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0336117 |
| RPS16 | ribosomal protein S16 | -0.0334928 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0334895 |
| RPL26 | ribosomal protein L26 | -0.033384 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0332123 |
| RPS5 | ribosomal protein S5 | -0.0331018 |
| TJP1 | tight junction protein 1 | -0.0328017 |
| RNF213 | ring finger protein 213 | -0.0326778 |
| RPL30 | ribosomal protein L30 | -0.0324968 |
| ARF1 | ADP-ribosylation factor 1 | -0.0322545 |
| RPL32 | ribosomal protein L32 | -0.0316707 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0316663 |
| FLNB | filamin B, beta | -0.0314247 |
| NRN1 | neuritin 1 | -0.0313988 |
| RPS23 | ribosomal protein S23 | -0.0309063 |
| ACTN4 | actinin, alpha 4 | -0.0308594 |
| RPS20 | ribosomal protein S20 | -0.030836 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0307658 |
| CCNI | cyclin I | -0.0306413 |
| RIGI | RNA sensor RIG-I | -0.0304761 |
| MYO1E | myosin IE | -0.0304631 |
| NPR2 | natriuretic peptide receptor 2 | -0.0301691 |
| CCND2 | cyclin D2 | -0.02975 |
| PTMA | prothymosin, alpha | -0.0294325 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0292702 |
| IRF1 | interferon regulatory factor 1 | -0.0288204 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.028726 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0287255 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0283234 |
| RPS19 | ribosomal protein S19 | -0.0278538 |
| OXSR1 | oxidative stress responsive 1 | -0.0275617 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0271551 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0269815 |
| XAF1 | XIAP associated factor 1 | -0.0267577 |
| RPL38 | ribosomal protein L38 | -0.0267536 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0267008 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0266409 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0263328 |
| RPS8 | ribosomal protein S8 | -0.0261712 |
| RACK1 | receptor for activated C kinase 1 | -0.0260925 |
| STK17A | serine/threonine kinase 17a | -0.0260266 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0260045 |
