| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0756437 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.050881 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0491963 |
| LDHA | lactate dehydrogenase A | 0.044143 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0407672 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0402558 |
| FNIP1 | folliculin interacting protein 1 | 0.0392853 |
| HDAC9 | histone deacetylase 9 | 0.0371843 |
| ENO1 | enolase 1, (alpha) | 0.0351389 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0328163 |
| PTMA | prothymosin, alpha | 0.0327569 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0322325 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300111 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0299935 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0290596 |
| YEATS2 | YEATS domain containing 2 | 0.0281772 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281184 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0276892 |
| MYOF | myoferlin | 0.0273652 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0266413 |
| EREG | epiregulin | 0.0264363 |
| PLK2 | polo-like kinase 2 | 0.0260906 |
| PCBP2 | poly(rC) binding protein 2 | 0.0257448 |
| ZNF292 | zinc finger protein 292 | 0.0256991 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0252941 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0249654 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247774 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.024449 |
| CENPF | centromere protein F, 350/400kDa | 0.0241377 |
| SLK | STE20-like kinase | 0.0241182 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0239503 |
| EXOC4 | exocyst complex component 4 | 0.0239056 |
| TP63 | tumor protein p63 | 0.0237108 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0236486 |
| ANXA1 | annexin A1 | 0.023343 |
| XPO1 | exportin 1 | 0.0229882 |
| MAP4 | microtubule-associated protein 4 | 0.0229562 |
| PTK2 | protein tyrosine kinase 2 | 0.0228406 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0225367 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0224502 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0221414 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.022068 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0219021 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218255 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0217292 |
| FMNL2 | formin-like 2 | 0.021628 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0215624 |
| SBF2 | SET binding factor 2 | 0.0214647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0214306 |
| SPAG9 | sperm associated antigen 9 | 0.0206532 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0205539 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.019908 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0198896 |
| GOLGA4 | golgin A4 | 0.0198077 |
| EGFR | epidermal growth factor receptor | 0.0198006 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0197009 |
| TNS3 | tensin 3 | 0.0196166 |
| SFPQ | splicing factor proline/glutamine-rich | 0.019428 |
| SET | SET nuclear proto-oncogene | 0.0191821 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0191714 |
| CADM2 | cell adhesion molecule 2 | 0.0191556 |
| CDK19 | cyclin-dependent kinase 19 | 0.01898 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0188974 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0187738 |
| PAPOLA | poly(A) polymerase alpha | 0.0186603 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0185426 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0182104 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0181613 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0181076 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0179749 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0179135 |
| LYST | lysosomal trafficking regulator | 0.0179068 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0174982 |
| PODXL | podocalyxin-like | 0.0172598 |
| ANKRD36 | ankyrin repeat domain 36 | 0.016992 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0169296 |
| PRELID2 | PRELI domain containing 2 | 0.0168174 |
| RBM39 | RNA binding motif protein 39 | 0.016669 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166292 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0164283 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0162137 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0161875 |
| ANLN | anillin, actin binding protein | 0.0160241 |
| STAG2 | stromal antigen 2 | 0.0159375 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0158842 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.015798 |
| TPM3 | tropomyosin 3 | 0.0157845 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0157103 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0154252 |
| RAD51B | RAD51 paralog B | 0.0153434 |
| RPS4X | ribosomal protein S4, X-linked | 0.0152202 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0151643 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0151452 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0148803 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0148559 |
| ZNF148 | zinc finger protein 148 | 0.0147817 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0146794 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0145645 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0144752 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0579628 |
| MT2A | metallothionein 2A | -0.0460784 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0454154 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0415414 |
| TXNRD1 | thioredoxin reductase 1 | -0.039991 |
| EGR1 | early growth response 1 | -0.0385522 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0358564 |
| ACTG1 | actin gamma 1 | -0.0299707 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0299422 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0286645 |
| MT1X | metallothionein 1X | -0.0257512 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0252247 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0219398 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0213801 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0196801 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0195632 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0191242 |
| TMSB4X | thymosin beta 4, X-linked | -0.0190014 |
| RPL35A | ribosomal protein L35a | -0.0187871 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0164708 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0147162 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.014529 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0145104 |
| RPLP1 | ribosomal protein, large, P1 | -0.0144203 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0140343 |
| CMIP | c-Maf inducing protein | -0.0139348 |
| HLA-B | major histocompatibility complex, class I, B | -0.0136413 |
| HMGA1 | high mobility group AT-hook 1 | -0.0133815 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0133202 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.013046 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0127356 |
| PDE10A | phosphodiesterase 10A | -0.0123873 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0121938 |
| TMEM41B | transmembrane protein 41B | -0.0116135 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.011599 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0115569 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0115489 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0115411 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0114051 |
| RGS4 | regulator of G-protein signaling 4 | -0.0112783 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0112477 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0111494 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0110436 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0108178 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0107808 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0107556 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.010637 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0106221 |
| ACTN1 | actinin, alpha 1 | -0.0103975 |
| RPL38 | ribosomal protein L38 | -0.0103739 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0102443 |
| CD44 | CD44 molecule (Indian blood group) | -0.010178 |
| SGMS2 | sphingomyelin synthase 2 | -0.0100524 |
| NEK10 | NIMA-related kinase 10 | -0.00969035 |
| RPL23 | ribosomal protein L23 | -0.0096566 |
| UPP1 | uridine phosphorylase 1 | -0.00962102 |
| BMERB1 | bMERB domain containing 1 | -0.00955387 |
| ARF1 | ADP-ribosylation factor 1 | -0.00950923 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00916401 |
| RPL4 | ribosomal protein L4 | -0.00906555 |
| RPL34 | ribosomal protein L34 | -0.0090579 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00904984 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.00903781 |
| ZNF267 | zinc finger protein 267 | -0.00893368 |
| RPL28 | ribosomal protein L28 | -0.00889926 |
| HOMER1 | homer scaffolding protein 1 | -0.00887761 |
| PLSCR1 | phospholipid scramblase 1 | -0.00883208 |
| CDCP1 | CUB domain containing protein 1 | -0.00881577 |
| OSMR | oncostatin M receptor | -0.00881459 |
| ARMC9 | armadillo repeat containing 9 | -0.0087478 |
| PYGB | phosphorylase, glycogen; brain | -0.00873348 |
| RPS24 | ribosomal protein S24 | -0.0087053 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00859392 |
| JUN | jun proto-oncogene | -0.00852572 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00844236 |
| PYGL | phosphorylase, glycogen, liver | -0.00843946 |
| FERMT1 | fermitin family member 1 | -0.00832946 |
| CCDC190 | coiled-coil domain containing 190 | -0.0082198 |
| FHL2 | four and a half LIM domains 2 | -0.00819651 |
| SP100 | SP100 nuclear antigen | -0.00801898 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.00797174 |
| RPS20 | ribosomal protein S20 | -0.00791457 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00776362 |
| PRNP | prion protein | -0.00775315 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.00773875 |
| HPCAL1 | hippocalcin-like 1 | -0.00772956 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00771414 |
| RPS28 | ribosomal protein S28 | -0.00748231 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00742703 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00741688 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00739409 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.007373 |
| RPL36A | ribosomal protein L36a | -0.00735374 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00733742 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.00730802 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.00728759 |
| PMP22 | peripheral myelin protein 22 | -0.00722327 |
| STK17A | serine/threonine kinase 17a | -0.00677515 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.00676276 |
| RASA2 | RAS p21 protein activator 2 | -0.00676044 |
