| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.229256 |
| ASPH | aspartate beta-hydroxylase | 0.147239 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.113701 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.112047 |
| FNDC3B | fibronectin type III domain containing 3B | 0.092493 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0907312 |
| LDHA | lactate dehydrogenase A | 0.0674743 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0603242 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0559078 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0533146 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0530442 |
| MYOF | myoferlin | 0.052844 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0505455 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.050071 |
| CAV2 | caveolin 2 | 0.049627 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0482821 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0471281 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.041817 |
| SCEL | sciellin | 0.0417882 |
| INTS6 | integrator complex subunit 6 | 0.0416267 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0415995 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0415799 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0400044 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0399083 |
| DSPP | dentin sialophosphoprotein | 0.0398684 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0393033 |
| KRT7 | keratin 7, type II | 0.039145 |
| ENO1 | enolase 1, (alpha) | 0.0383101 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0365926 |
| FAM13A | family with sequence similarity 13, member A | 0.0358726 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0340268 |
| PKM | pyruvate kinase, muscle | 0.0337862 |
| MSN | moesin | 0.0335601 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0330526 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0326705 |
| PDE8A | phosphodiesterase 8A | 0.0326179 |
| RNF213 | ring finger protein 213 | 0.0320954 |
| PCBP2 | poly(rC) binding protein 2 | 0.0320907 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0319746 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0314769 |
| GRAMD1B | GRAM domain containing 1B | 0.0308728 |
| CPE | carboxypeptidase E | 0.0304909 |
| CUX1 | cut-like homeobox 1 | 0.0296193 |
| PTK2 | protein tyrosine kinase 2 | 0.0295278 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0290525 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0288092 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0285814 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0280527 |
| MYO1E | myosin IE | 0.0278542 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0278305 |
| SLK | STE20-like kinase | 0.0277116 |
| MCU | mitochondrial calcium uniporter | 0.0274379 |
| RPS3 | ribosomal protein S3 | 0.0272774 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0268968 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0265909 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0262969 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0259762 |
| TMSB10 | thymosin beta 10 | 0.0259295 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0258927 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0257635 |
| B2M | beta-2-microglobulin | 0.0254102 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025397 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0253625 |
| NTN4 | netrin 4 | 0.0253602 |
| CST3 | cystatin C | 0.025166 |
| FLNB | filamin B, beta | 0.0246861 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0243936 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0243392 |
| POTEF | POTE ankyrin domain family, member F | 0.0241901 |
| AHR | aryl hydrocarbon receptor | 0.0240369 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0239862 |
| PTEN | phosphatase and tensin homolog | 0.0239714 |
| CMIP | c-Maf inducing protein | 0.023794 |
| TNS3 | tensin 3 | 0.0237371 |
| CTBP2 | C-terminal binding protein 2 | 0.023535 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0231734 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0231485 |
| USP53 | ubiquitin specific peptidase 53 | 0.023118 |
| GPC6 | glypican 6 | 0.0231177 |
| VEGFA | vascular endothelial growth factor A | 0.0228741 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0225434 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0220596 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0218032 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0216978 |
| RAD51B | RAD51 paralog B | 0.0213939 |
| PRKCA | protein kinase C, alpha | 0.0212829 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0212075 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0211862 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0209776 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0208494 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0207977 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0207554 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0206472 |
| MED13L | mediator complex subunit 13-like | 0.0205986 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0205683 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0205439 |
| STC2 | stanniocalcin 2 | 0.0205181 |
| TPM3 | tropomyosin 3 | 0.020093 |
| VCL | vinculin | 0.0199759 |
| EFNA5 | ephrin-A5 | 0.0199046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.148974 |
| TXNRD1 | thioredoxin reductase 1 | -0.0811683 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0770755 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0676552 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0651017 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0636388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0630737 |
| LOC112694756 | uncharaterized LOC112694756 | -0.062884 |
| OSMR | oncostatin M receptor | -0.0625396 |
| LAMA4 | laminin, alpha 4 | -0.0588688 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0547504 |
| LAMC2 | laminin, gamma 2 | -0.0541331 |
| NDRG1 | N-myc downstream regulated 1 | -0.0533399 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0529086 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.046889 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0464699 |
| GM2A | GM2 ganglioside activator | -0.0450478 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0434658 |
| MT2A | metallothionein 2A | -0.0421307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0414849 |
| LAMB3 | laminin, beta 3 | -0.0375422 |
| CANX | calnexin | -0.037513 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0370671 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0353265 |
| NABP1 | nucleic acid binding protein 1 | -0.0352353 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0350464 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0346074 |
| TOP1 | topoisomerase (DNA) I | -0.0343786 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0338081 |
| CES1 | carboxylesterase 1 | -0.0336386 |
| H1-0 | H1.0 linker histone | -0.0335004 |
| HDLBP | high density lipoprotein binding protein | -0.032688 |
| ABLIM1 | actin binding LIM protein 1 | -0.031543 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312332 |
| AHNAK | AHNAK nucleoprotein | -0.0300389 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0298029 |
| RUNX1 | runt-related transcription factor 1 | -0.0285825 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0277862 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0277074 |
| NGLY1 | N-glycanase 1 | -0.0275159 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0270486 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0269496 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0265421 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0263738 |
| STC1 | stanniocalcin 1 | -0.0261553 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0259862 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0258236 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0255209 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0254151 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.025372 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0250516 |
| WDR45B | WD repeat domain 45B | -0.0248985 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0245815 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0242045 |
| IER3 | immediate early response 3 | -0.0237093 |
| SLTM | SAFB-like, transcription modulator | -0.0235047 |
| RPL4 | ribosomal protein L4 | -0.0222137 |
| MT1X | metallothionein 1X | -0.0217129 |
| RPLP0 | ribosomal protein, large, P0 | -0.0215823 |
| ANKRD10 | ankyrin repeat domain 10 | -0.020919 |
| RPS24 | ribosomal protein S24 | -0.0207257 |
| CDCP1 | CUB domain containing protein 1 | -0.020515 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0204426 |
| SEPTIN10 | septin 10 | -0.0202521 |
| HBP1 | HMG-box transcription factor 1 | -0.0201767 |
| RNF169 | ring finger protein 169 | -0.0201334 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0201083 |
| HLA-B | major histocompatibility complex, class I, B | -0.0198751 |
| METTL9 | methyltransferase like 9 | -0.01943 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.01935 |
| ARF1 | ADP-ribosylation factor 1 | -0.0193103 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0191071 |
| FAM110C | family with sequence similarity 110, member C | -0.0190395 |
| GPATCH2L | G patch domain containing 2-like | -0.0189605 |
| TMEM165 | transmembrane protein 165 | -0.0187691 |
| UBC | ubiquitin C | -0.0187571 |
| ATG7 | autophagy related 7 | -0.0185947 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0185527 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0185136 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0184758 |
| CCNI | cyclin I | -0.0184595 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0184097 |
| USP34 | ubiquitin specific peptidase 34 | -0.0183344 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0180967 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0178851 |
| FRY | furry homolog (Drosophila) | -0.0177399 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0176652 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0175275 |
| OGA | O-GlcNAcase | -0.0174453 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0173682 |
| RASA2 | RAS p21 protein activator 2 | -0.0173229 |
| CSNK1E | casein kinase 1, epsilon | -0.0172113 |
| PLEC | plectin | -0.0170014 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0169766 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0167314 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0166498 |
| SDC4 | syndecan 4 | -0.0166032 |
| EMP2 | epithelial membrane protein 2 | -0.0165339 |
| TRIM56 | tripartite motif containing 56 | -0.0162213 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.0161866 |
