| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.317427 |
| GRAMD1B | GRAM domain containing 1B | 0.193123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.146121 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.116158 |
| PM20D1 | peptidase M20 domain containing 1 | 0.114662 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0961019 |
| FGB | fibrinogen beta chain | 0.0861059 |
| WDR43 | WD repeat domain 43 | 0.0690314 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656675 |
| HDAC9 | histone deacetylase 9 | 0.0606179 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0590281 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0539598 |
| FTL | ferritin, light polypeptide | 0.0536851 |
| RTN4 | reticulon 4 | 0.0534905 |
| PTK2 | protein tyrosine kinase 2 | 0.0528111 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0516976 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0505631 |
| FAM168A | family with sequence similarity 168, member A | 0.0460997 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0448133 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0446579 |
| USP3 | ubiquitin specific peptidase 3 | 0.0428177 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0426376 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0412776 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0411881 |
| CCNL1 | cyclin L1 | 0.040712 |
| WWOX | WW domain containing oxidoreductase | 0.0402406 |
| YBX3 | Y box binding protein 3 | 0.0388873 |
| KLF6 | Kruppel-like factor 6 | 0.0384771 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0381913 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.038156 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0372479 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367505 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.036019 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0355125 |
| AHR | aryl hydrocarbon receptor | 0.0354195 |
| RASAL2 | RAS protein activator like 2 | 0.0352014 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0345691 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0341734 |
| ASPH | aspartate beta-hydroxylase | 0.0341274 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0338374 |
| TPM3 | tropomyosin 3 | 0.0337921 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0335375 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0326782 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0322119 |
| PTMA | prothymosin, alpha | 0.0320281 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0317625 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0314429 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0312364 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0307882 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0307361 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0306273 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0305383 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0301345 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300573 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0296586 |
| FGG | fibrinogen gamma chain | 0.0294796 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0292327 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0290376 |
| ILF2 | interleukin enhancer binding factor 2 | 0.0286829 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286219 |
| TPD52 | tumor protein D52 | 0.0284554 |
| RNF145 | ring finger protein 145 | 0.0283474 |
| NUP58 | nucleoporin 58 | 0.0283139 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0281503 |
| MATR3 | matrin 3 | 0.028093 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0279746 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0277538 |
| JMJD1C | jumonji domain containing 1C | 0.027734 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0274576 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.027173 |
| NTN4 | netrin 4 | 0.0271423 |
| DENND4A | DENN/MADD domain containing 4A | 0.0264526 |
| CRY1 | cryptochrome circadian clock 1 | 0.0263784 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.026374 |
| NUP153 | nucleoporin 153kDa | 0.0262706 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0260461 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0259722 |
| NRG1 | neuregulin 1 | 0.0257219 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0257165 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0256805 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0255262 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.025359 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0251773 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0249218 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0248999 |
| ZNF292 | zinc finger protein 292 | 0.024867 |
| TNPO1 | transportin 1 | 0.0248302 |
| RAD21 | RAD21 homolog (S. pombe) | 0.024809 |
| ERBIN | erbb2 interacting protein | 0.0248055 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.024797 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0244228 |
| RHEB | Ras homolog enriched in brain | 0.0243634 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0243365 |
| WBP11 | WW domain binding protein 11 | 0.0241467 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0240466 |
| VMP1 | vacuole membrane protein 1 | 0.0240205 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0239952 |
| SPAG9 | sperm associated antigen 9 | 0.023552 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0234169 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0234062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.170616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14484 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.107052 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.102439 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0951422 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0905895 |
| TMSB10 | thymosin beta 10 | -0.0884529 |
| PYGL | phosphorylase, glycogen, liver | -0.0690482 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0602765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0489262 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.048615 |
| CMIP | c-Maf inducing protein | -0.0484199 |
| VIM | vimentin | -0.0482637 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0466059 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0460116 |
| AHNAK | AHNAK nucleoprotein | -0.0426357 |
| HLA-B | major histocompatibility complex, class I, B | -0.0422972 |
| EGFR | epidermal growth factor receptor | -0.0410595 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0387561 |
| FLNB | filamin B, beta | -0.0383435 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0374691 |
| ACTG1 | actin gamma 1 | -0.03714 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0364401 |
| NDRG1 | N-myc downstream regulated 1 | -0.0358793 |
| S100A10 | S100 calcium binding protein A10 | -0.0349275 |
| FMNL2 | formin-like 2 | -0.0342747 |
| STC1 | stanniocalcin 1 | -0.0342087 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0339384 |
| IER3 | immediate early response 3 | -0.0326214 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0319467 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0318658 |
| RPL23 | ribosomal protein L23 | -0.0318263 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0315412 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0309545 |
| MYO1E | myosin IE | -0.0308952 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0305926 |
| S100A6 | S100 calcium binding protein A6 | -0.0298199 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0297601 |
| RPLP1 | ribosomal protein, large, P1 | -0.0296712 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0293539 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283151 |
| CAVIN1 | caveolae associated protein 1 | -0.0276732 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0274436 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.02744 |
| ACTN1 | actinin, alpha 1 | -0.026491 |
| VCL | vinculin | -0.0264789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0264091 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0254241 |
| ANGPTL4 | angiopoietin-like 4 | -0.0251552 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0250111 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0247474 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0243311 |
| ATXN1 | ataxin 1 | -0.0236223 |
| NEBL | nebulette | -0.0232192 |
| HLA-E | major histocompatibility complex, class I, E | -0.0229709 |
| SNX14 | sorting nexin 14 | -0.0229708 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0228697 |
| RPS8 | ribosomal protein S8 | -0.0226267 |
| RPL34 | ribosomal protein L34 | -0.0225722 |
| EGR1 | early growth response 1 | -0.0224563 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0220324 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0219166 |
| HLA-A | major histocompatibility complex, class I, A | -0.021572 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0211375 |
| STK17A | serine/threonine kinase 17a | -0.0208097 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0206816 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0205258 |
| NUP98 | nucleoporin 98kDa | -0.0203778 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0200632 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0195674 |
| MORF4L2 | mortality factor 4 like 2 | -0.019496 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0190686 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0190077 |
| FUS | FUS RNA binding protein | -0.0189521 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0189151 |
| INTS6 | integrator complex subunit 6 | -0.0185726 |
| RPL35A | ribosomal protein L35a | -0.0185459 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0184513 |
| LAMC2 | laminin, gamma 2 | -0.0184481 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0181238 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0179974 |
| NUMB | numb homolog (Drosophila) | -0.0179795 |
| CD99 | CD99 molecule | -0.017915 |
| HM13 | histocompatibility (minor) 13 | -0.0175295 |
| ATG7 | autophagy related 7 | -0.0175157 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0173622 |
| MT1X | metallothionein 1X | -0.0172401 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0170346 |
| OSMR | oncostatin M receptor | -0.0170331 |
| CALR | calreticulin | -0.0168783 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0166789 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0166055 |
| ARF4 | ADP-ribosylation factor 4 | -0.0165597 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0164857 |
| CDCP1 | CUB domain containing protein 1 | -0.0164369 |
| PCNX4 | pecanex 4 | -0.0164217 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0163717 |
| RPL31 | ribosomal protein L31 | -0.0162914 |
| RPL37A | ribosomal protein L37a | -0.0158872 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0158772 |
