| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perindopril (erbumine)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0906045 |
| MUC16 | mucin 16, cell surface associated | 0.087739 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0846344 |
| TXNRD1 | thioredoxin reductase 1 | 0.080456 |
| EGFR | epidermal growth factor receptor | 0.0794874 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0720386 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.071332 |
| IGF2 | insulin-like growth factor 2 | 0.0679567 |
| SMYD3 | SET and MYND domain containing 3 | 0.06523 |
| KYNU | kynureninase | 0.0633581 |
| NAV2 | neuron navigator 2 | 0.0628792 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0614558 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0603479 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0599373 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0599343 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0594939 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0575394 |
| RBM47 | RNA binding motif protein 47 | 0.0566362 |
| MYOF | myoferlin | 0.0561828 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0548375 |
| NUP58 | nucleoporin 58 | 0.0529916 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0522938 |
| ZNF654 | zinc finger protein 654 | 0.0519603 |
| NBEA | neurobeachin | 0.0519547 |
| PDE10A | phosphodiesterase 10A | 0.0514821 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0508577 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0499874 |
| EFNA5 | ephrin-A5 | 0.0493147 |
| ATXN1 | ataxin 1 | 0.0480343 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0480191 |
| STK17A | serine/threonine kinase 17a | 0.0477645 |
| EHBP1 | EH domain binding protein 1 | 0.0476949 |
| POU2F1 | POU class 2 homeobox 1 | 0.0468147 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0465344 |
| ZNF292 | zinc finger protein 292 | 0.0461874 |
| STEAP4 | STEAP family member 4 | 0.0455474 |
| RNF213 | ring finger protein 213 | 0.0455277 |
| DIAPH2 | diaphanous-related formin 2 | 0.0444139 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0441772 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0439973 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0437288 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0434333 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0431527 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0429686 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0425531 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0422076 |
| YAP1 | Yes-associated protein 1 | 0.0414125 |
| GPHN | gephyrin | 0.0400119 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0397317 |
| AHNAK | AHNAK nucleoprotein | 0.0392849 |
| PKN2 | protein kinase N2 | 0.0391841 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0389411 |
| MED13 | mediator complex subunit 13 | 0.0388785 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0380498 |
| NLGN1 | neuroligin 1 | 0.0380014 |
| NEBL | nebulette | 0.037845 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0377668 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0377491 |
| LDHA | lactate dehydrogenase A | 0.0376564 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0374593 |
| CTBP2 | C-terminal binding protein 2 | 0.0372892 |
| ZNF638 | zinc finger protein 638 | 0.037226 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370537 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0366265 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0364811 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0361943 |
| RIGI | RNA sensor RIG-I | 0.0359914 |
| RTN4 | reticulon 4 | 0.0358992 |
| B2M | beta-2-microglobulin | 0.0356334 |
| ATXN2 | ataxin 2 | 0.0356322 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0352825 |
| CD44 | CD44 molecule (Indian blood group) | 0.0349065 |
| SEPTIN9 | septin 9 | 0.0348782 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0344992 |
| RGS6 | regulator of G-protein signaling 6 | 0.0338745 |
| SLK | STE20-like kinase | 0.0337702 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0336851 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0335647 |
| ITGA6 | integrin, alpha 6 | 0.0335124 |
| UBE3C | ubiquitin protein ligase E3C | 0.0333973 |
| LMO7 | LIM domain 7 | 0.0333645 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0331625 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0330646 |
| ATP11A | ATPase, class VI, type 11A | 0.0329736 |
| FAT1 | FAT atypical cadherin 1 | 0.0327849 |
| JMJD1C | jumonji domain containing 1C | 0.0327363 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0327095 |
| RFX7 | regulatory factor X, 7 | 0.0321833 |
| ANLN | anillin, actin binding protein | 0.0319448 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0317802 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0312834 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0310555 |
| NCKAP1 | NCK-associated protein 1 | 0.0308989 |
| FN1 | fibronectin 1 | 0.0307759 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0307471 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0306492 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0305957 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0305724 |
| PHF3 | PHD finger protein 3 | 0.0305168 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0301263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.196827 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171139 |
| TMSB10 | thymosin beta 10 | -0.137084 |
| RPL35A | ribosomal protein L35a | -0.105499 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.104328 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0845519 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0824359 |
| MT2A | metallothionein 2A | -0.0806186 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0766683 |
| PTMA | prothymosin, alpha | -0.0743653 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0735078 |
| SRPK2 | SRSF protein kinase 2 | -0.0733026 |
| RPL12 | ribosomal protein L12 | -0.068281 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0669716 |
| ANXA2 | annexin A2 | -0.0654693 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0652027 |
| VIM | vimentin | -0.0633988 |
| RPS8 | ribosomal protein S8 | -0.0620222 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0617118 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0612254 |
| S100A10 | S100 calcium binding protein A10 | -0.0558017 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0553122 |
| LOC112694756 | uncharaterized LOC112694756 | -0.055003 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0546535 |
| PKM | pyruvate kinase, muscle | -0.0542444 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0542377 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0540857 |
| MCL1 | myeloid cell leukemia 1 | -0.0538294 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.053734 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0532778 |
| RPLP1 | ribosomal protein, large, P1 | -0.0524965 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0520417 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0516636 |
| RPS19 | ribosomal protein S19 | -0.0515239 |
| UBC | ubiquitin C | -0.0515068 |
| MYO1E | myosin IE | -0.0501441 |
| RPS3 | ribosomal protein S3 | -0.0493619 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0484528 |
| FNIP1 | folliculin interacting protein 1 | -0.0483156 |
| RPL23 | ribosomal protein L23 | -0.0480618 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.047649 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0472767 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0467971 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0464632 |
| RORA | RAR-related orphan receptor A | -0.0454924 |
| S100A6 | S100 calcium binding protein A6 | -0.0453858 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0450274 |
| KRT17 | keratin 17, type I | -0.0450183 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0444624 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0444447 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0441945 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0441926 |
| RPS4X | ribosomal protein S4, X-linked | -0.0440768 |
| INTS6 | integrator complex subunit 6 | -0.0438479 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0431774 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0425695 |
| RPL31 | ribosomal protein L31 | -0.0417036 |
| AFAP1 | actin filament associated protein 1 | -0.0416935 |
| RPS6 | ribosomal protein S6 | -0.0412955 |
| DICER1 | dicer 1, ribonuclease type III | -0.0410893 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0406096 |
| VMP1 | vacuole membrane protein 1 | -0.040287 |
| NPTN | neuroplastin | -0.0399565 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0391037 |
| POTEF | POTE ankyrin domain family, member F | -0.0389768 |
| RPS13 | ribosomal protein S13 | -0.0389254 |
| TAOK3 | TAO kinase 3 | -0.0388231 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0388154 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0384677 |
| ARF1 | ADP-ribosylation factor 1 | -0.0381944 |
| TMSB4X | thymosin beta 4, X-linked | -0.0379998 |
| RPS24 | ribosomal protein S24 | -0.0378981 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0375058 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0369494 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0366415 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0362264 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0359372 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0356527 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0356133 |
| MYO6 | myosin VI | -0.0350395 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0349128 |
| CD2AP | CD2-associated protein | -0.0348645 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.034853 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0345364 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0342429 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0337936 |
| TMEM41B | transmembrane protein 41B | -0.0336194 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0335748 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0332275 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0331899 |
| RPL36 | ribosomal protein L36 | -0.0330885 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.032375 |
| IL6ST | interleukin 6 signal transducer | -0.0318013 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0317074 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0317039 |
| PPHLN1 | periphilin 1 | -0.0315599 |
| USP53 | ubiquitin specific peptidase 53 | -0.0313384 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0311796 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0311348 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0309402 |
