| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0794716 |
| DST | dystonin | 0.0762337 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.072167 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0682861 |
| PDE10A | phosphodiesterase 10A | 0.0633659 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0615894 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0608994 |
| NLGN1 | neuroligin 1 | 0.0606325 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0590378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0585751 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0551682 |
| EHBP1 | EH domain binding protein 1 | 0.0543924 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0541041 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.053264 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.052557 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0493239 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0491751 |
| GPHN | gephyrin | 0.0488375 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0481952 |
| HELZ | helicase with zinc finger | 0.0475521 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0466149 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0456698 |
| PTK2 | protein tyrosine kinase 2 | 0.0454327 |
| GPC6 | glypican 6 | 0.0446235 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0445124 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0438972 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.043793 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0436166 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0435318 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0433824 |
| ZNF638 | zinc finger protein 638 | 0.0424515 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0421542 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0415617 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.03963 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0394358 |
| FMNL2 | formin-like 2 | 0.038501 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0374315 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0373776 |
| NKTR | natural killer cell triggering receptor | 0.0367813 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0365538 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0362219 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0360612 |
| COG5 | component of oligomeric golgi complex 5 | 0.0359117 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0352193 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0346964 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.034664 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0346363 |
| FLNB | filamin B, beta | 0.03412 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0332061 |
| PKM | pyruvate kinase, muscle | 0.0330523 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0330143 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0326587 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0325368 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0313963 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0307449 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0307351 |
| NBAS | neuroblastoma amplified sequence | 0.0298134 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0282609 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0281628 |
| MED13L | mediator complex subunit 13-like | 0.027704 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0275527 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0271346 |
| OGA | O-GlcNAcase | 0.0271202 |
| SPAG9 | sperm associated antigen 9 | 0.0267467 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0266893 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0254454 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0251187 |
| RPL11 | ribosomal protein L11 | 0.0241377 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0241012 |
| MAP4 | microtubule-associated protein 4 | 0.0230316 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0228848 |
| SETD5 | SET domain containing 5 | 0.0225231 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222329 |
| RAD51B | RAD51 paralog B | 0.0221496 |
| FAT1 | FAT atypical cadherin 1 | 0.0218735 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0215496 |
| AREG | amphiregulin | 0.0208284 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0202175 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0201334 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0200449 |
| RORA | RAR-related orphan receptor A | 0.0198998 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0197981 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0194909 |
| LDHA | lactate dehydrogenase A | 0.0174006 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.017275 |
| MATR3 | matrin 3 | 0.0172393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0172391 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0170483 |
| TSC22D2 | TSC22 domain family, member 2 | 0.016885 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.016709 |
| ACTG1 | actin gamma 1 | 0.0165982 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0162523 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0154059 |
| ATP13A3 | ATPase type 13A3 | 0.01512 |
| YME1L1 | YME1-like 1 ATPase | 0.0151139 |
| RBM39 | RNA binding motif protein 39 | 0.0141453 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0133667 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0131913 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0124942 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0123085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.13994 |
| EGFR | epidermal growth factor receptor | -0.0907924 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0827184 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0799211 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.073747 |
| TMSB10 | thymosin beta 10 | -0.0661517 |
| HDLBP | high density lipoprotein binding protein | -0.059183 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0585626 |
| RPL26 | ribosomal protein L26 | -0.0572636 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0570978 |
| B2M | beta-2-microglobulin | -0.0558719 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0550556 |
| MT2A | metallothionein 2A | -0.0550148 |
| RPLP1 | ribosomal protein, large, P1 | -0.0482967 |
| RPS24 | ribosomal protein S24 | -0.048029 |
| FTL | ferritin, light polypeptide | -0.0475775 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0460781 |
| MORF4L2 | mortality factor 4 like 2 | -0.0434147 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0428908 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0424263 |
| RPL35A | ribosomal protein L35a | -0.0404766 |
| PTMA | prothymosin, alpha | -0.0402091 |
| RPS6 | ribosomal protein S6 | -0.0390118 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0375271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0372468 |
| CALR | calreticulin | -0.0370393 |
| RRBP1 | ribosome binding protein 1 | -0.0369233 |
| YBX3 | Y box binding protein 3 | -0.0364635 |
| RBM25 | RNA binding motif protein 25 | -0.0362977 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0351841 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0349665 |
| LMNA | lamin A/C | -0.0347329 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0345257 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.034199 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0341337 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0331006 |
| SP100 | SP100 nuclear antigen | -0.0330028 |
| TXNIP | thioredoxin interacting protein | -0.0329333 |
| KIF5B | kinesin family member 5B | -0.0308757 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0305774 |
| CDC73 | cell division cycle 73 | -0.0302553 |
| POTEF | POTE ankyrin domain family, member F | -0.0294789 |
| VCL | vinculin | -0.0286336 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0279915 |
| RPS12 | ribosomal protein S12 | -0.0279726 |
| DIAPH2 | diaphanous-related formin 2 | -0.0279673 |
| LAMA4 | laminin, alpha 4 | -0.0275566 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0275389 |
| CCNI | cyclin I | -0.0271254 |
| SYT1 | synaptotagmin I | -0.0264559 |
| MTDH | metadherin | -0.0263968 |
| ZNF292 | zinc finger protein 292 | -0.0262294 |
| EFNA5 | ephrin-A5 | -0.0258093 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.025228 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0252134 |
| RPL9 | ribosomal protein L9 | -0.0235529 |
| HLA-B | major histocompatibility complex, class I, B | -0.0234527 |
| SMYD3 | SET and MYND domain containing 3 | -0.0234146 |
| IGF2 | insulin-like growth factor 2 | -0.0233686 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0232626 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0224994 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0223 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0216241 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0215924 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.020715 |
| FUS | FUS RNA binding protein | -0.020478 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0195558 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0188915 |
| SQSTM1 | sequestosome 1 | -0.0185283 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0183895 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0177662 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0176106 |
| RPL12 | ribosomal protein L12 | -0.0174916 |
| RPS13 | ribosomal protein S13 | -0.0174856 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0171943 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.016949 |
| RPS19 | ribosomal protein S19 | -0.0169366 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0169124 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0168583 |
| RACK1 | receptor for activated C kinase 1 | -0.0168122 |
| EXOC4 | exocyst complex component 4 | -0.016478 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0164593 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.016379 |
| CORO1C | coronin, actin binding protein, 1C | -0.0160701 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0156979 |
| LMO7 | LIM domain 7 | -0.0156252 |
| TOP1 | topoisomerase (DNA) I | -0.0155639 |
| SBF2 | SET binding factor 2 | -0.0153123 |
| RPL4 | ribosomal protein L4 | -0.0150527 |
| RPS8 | ribosomal protein S8 | -0.014823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0143154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0143038 |
| FOXJ3 | forkhead box J3 | -0.0133683 |
| MED13 | mediator complex subunit 13 | -0.0132854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0127192 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0125508 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0125276 |
| STK24 | serine/threonine kinase 24 | -0.0122269 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0117811 |
| STC1 | stanniocalcin 1 | -0.0116247 |
