| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.190374 |
| LAMB3 | laminin, beta 3 | 0.157235 |
| EMP1 | epithelial membrane protein 1 | 0.151996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.143284 |
| ANXA2 | annexin A2 | 0.120983 |
| LAMA4 | laminin, alpha 4 | 0.10984 |
| EZR | ezrin | 0.100482 |
| MYO6 | myosin VI | 0.0931648 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.078577 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.074189 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0668053 |
| FN1 | fibronectin 1 | 0.0656619 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0634743 |
| SVIL | supervillin | 0.0633777 |
| DSG2 | desmoglein 2 | 0.0630588 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0628329 |
| SMAD3 | SMAD family member 3 | 0.0618943 |
| ERBIN | erbb2 interacting protein | 0.061179 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.059972 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0597651 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0591145 |
| LDHA | lactate dehydrogenase A | 0.0583888 |
| RASAL2 | RAS protein activator like 2 | 0.0580616 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0565267 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0553461 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0546989 |
| MYO1E | myosin IE | 0.0534905 |
| LAMC2 | laminin, gamma 2 | 0.0533006 |
| EGFR | epidermal growth factor receptor | 0.0527921 |
| JMJD1C | jumonji domain containing 1C | 0.0527686 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0525792 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0498898 |
| ASPH | aspartate beta-hydroxylase | 0.0485195 |
| GOLGB1 | golgin B1 | 0.048316 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0479959 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0475822 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.044074 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0422404 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0409348 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0408679 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0404478 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0402849 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0400807 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0398885 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0388172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0386663 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0385324 |
| MYOF | myoferlin | 0.0380081 |
| EHF | ets homologous factor | 0.037989 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0379887 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0378547 |
| RUNX1 | runt-related transcription factor 1 | 0.0377485 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0376833 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0370268 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0365569 |
| FAM107B | family with sequence similarity 107, member B | 0.0362564 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0360145 |
| CDK6 | cyclin-dependent kinase 6 | 0.0359539 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0358336 |
| PLSCR1 | phospholipid scramblase 1 | 0.0358257 |
| HDAC9 | histone deacetylase 9 | 0.0354966 |
| MYO5B | myosin VB | 0.0354903 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0350938 |
| CD47 | CD47 molecule | 0.0343805 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0337813 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0337481 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.033742 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0335215 |
| ANXA1 | annexin A1 | 0.0334987 |
| SGMS2 | sphingomyelin synthase 2 | 0.033405 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0330134 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0327554 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0327308 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0326418 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0324902 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0324825 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0324341 |
| CD2AP | CD2-associated protein | 0.0323881 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0323553 |
| SLTM | SAFB-like, transcription modulator | 0.0322813 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0321707 |
| FNIP1 | folliculin interacting protein 1 | 0.031684 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0306636 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0303299 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0303231 |
| INTS6 | integrator complex subunit 6 | 0.0302595 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0300145 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0293255 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292402 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0292367 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0292318 |
| BRD2 | bromodomain containing 2 | 0.028972 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0288227 |
| VMP1 | vacuole membrane protein 1 | 0.0287401 |
| EHBP1 | EH domain binding protein 1 | 0.0284588 |
| USP34 | ubiquitin specific peptidase 34 | 0.0281388 |
| ATF3 | activating transcription factor 3 | 0.0280077 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0278795 |
| LIPH | lipase, member H | 0.0277739 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.027693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27307 |
| RPL35A | ribosomal protein L35a | -0.0976683 |
| RPL23 | ribosomal protein L23 | -0.0909498 |
| RPS6 | ribosomal protein S6 | -0.0893763 |
| TMSB10 | thymosin beta 10 | -0.0850309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0776047 |
| RPLP1 | ribosomal protein, large, P1 | -0.0729636 |
| RPS19 | ribosomal protein S19 | -0.0593053 |
| FOSL1 | FOS-like antigen 1 | -0.0544703 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0540276 |
| PTMA | prothymosin, alpha | -0.053051 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0523962 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0503159 |
| FTL | ferritin, light polypeptide | -0.0494384 |
| RPS13 | ribosomal protein S13 | -0.0467874 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0466705 |
| RPS8 | ribosomal protein S8 | -0.0465003 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0451115 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0444945 |
| HMGA1 | high mobility group AT-hook 1 | -0.0435718 |
| RPLP2 | ribosomal protein, large, P2 | -0.0409917 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0392431 |
| RPS24 | ribosomal protein S24 | -0.0391944 |
| MT2A | metallothionein 2A | -0.0383286 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0377436 |
| RPS23 | ribosomal protein S23 | -0.0371608 |
| RPS15 | ribosomal protein S15 | -0.0368173 |
| RPS14 | ribosomal protein S14 | -0.0367053 |
| RACK1 | receptor for activated C kinase 1 | -0.0357303 |
| RPS12 | ribosomal protein S12 | -0.0348446 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.03457 |
| RPL36A | ribosomal protein L36a | -0.0340745 |
| RPL34 | ribosomal protein L34 | -0.0333304 |
| RPL36 | ribosomal protein L36 | -0.0325739 |
| RPL31 | ribosomal protein L31 | -0.0325141 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0324158 |
| RPS25 | ribosomal protein S25 | -0.0318114 |
| RPL35 | ribosomal protein L35 | -0.0310488 |
| VIM | vimentin | -0.030767 |
| RPS21 | ribosomal protein S21 | -0.0299757 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0294326 |
| CCNL1 | cyclin L1 | -0.0294203 |
| PDE8A | phosphodiesterase 8A | -0.0290438 |
| S100A10 | S100 calcium binding protein A10 | -0.0289182 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0287069 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0286353 |
| S100A6 | S100 calcium binding protein A6 | -0.0284453 |
| RPL28 | ribosomal protein L28 | -0.0283296 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0282916 |
| RPS27 | ribosomal protein S27 | -0.0281878 |
| HLA-B | major histocompatibility complex, class I, B | -0.0281644 |
| RPL12 | ribosomal protein L12 | -0.0280355 |
| RPL19 | ribosomal protein L19 | -0.0280335 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0279139 |
| RPS17 | ribosomal protein S17 | -0.0279017 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0277102 |
| HLA-A | major histocompatibility complex, class I, A | -0.0275236 |
| RPL32 | ribosomal protein L32 | -0.0274277 |
| RPS5 | ribosomal protein S5 | -0.0274267 |
| TMEM123 | transmembrane protein 123 | -0.0272392 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0271083 |
| WWC1 | WW and C2 domain containing 1 | -0.026583 |
| RPL9 | ribosomal protein L9 | -0.02624 |
| EGR1 | early growth response 1 | -0.0260061 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259063 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0257199 |
| RPS20 | ribosomal protein S20 | -0.0256176 |
| RPL21 | ribosomal protein L21 | -0.0255101 |
| RPLP0 | ribosomal protein, large, P0 | -0.0254307 |
| RPL8 | ribosomal protein L8 | -0.0250997 |
| TAPBP | TAP binding protein (tapasin) | -0.0247717 |
| DEK | DEK proto-oncogene | -0.0244541 |
| RPS11 | ribosomal protein S11 | -0.023919 |
| S100A9 | S100 calcium binding protein A9 | -0.0237569 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0236198 |
| PRELID2 | PRELI domain containing 2 | -0.0235802 |
| POTEF | POTE ankyrin domain family, member F | -0.0234016 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0233127 |
| HMGB1 | high mobility group box 1 | -0.0232156 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0230065 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0229256 |
| RPS16 | ribosomal protein S16 | -0.0228031 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0226653 |
| CENPF | centromere protein F, 350/400kDa | -0.0226229 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0225152 |
| RPL30 | ribosomal protein L30 | -0.0223197 |
| RPL11 | ribosomal protein L11 | -0.0222497 |
| RPL37 | ribosomal protein L37 | -0.0216052 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0214077 |
| RPL15 | ribosomal protein L15 | -0.021046 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0205152 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0203533 |
| IFI44 | interferon-induced protein 44 | -0.0201961 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0201813 |
| PGK1 | phosphoglycerate kinase 1 | -0.0200419 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0198786 |
| RPL37A | ribosomal protein L37a | -0.0196856 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0196264 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0195976 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0191071 |
