| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.203101 |
| CENPF | centromere protein F, 350/400kDa | 0.0520301 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0416222 |
| GOLGA4 | golgin A4 | 0.0401979 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0357376 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0341813 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0332284 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0319306 |
| MKI67 | marker of proliferation Ki-67 | 0.0310502 |
| THBS1 | thrombospondin 1 | 0.0309563 |
| PGK1 | phosphoglycerate kinase 1 | 0.030753 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0291322 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0289181 |
| TPX2 | TPX2, microtubule-associated | 0.028804 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.028447 |
| RBM39 | RNA binding motif protein 39 | 0.0276882 |
| DIAPH3 | diaphanous-related formin 3 | 0.0271704 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0269342 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026541 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0265263 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0259314 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.025567 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.025276 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.024896 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0239551 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0238645 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0237782 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.023579 |
| CLTC | clathrin, heavy chain (Hc) | 0.023537 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0234548 |
| ANLN | anillin, actin binding protein | 0.0233874 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0230839 |
| ANXA2 | annexin A2 | 0.0229515 |
| NF1 | neurofibromin 1 | 0.0229168 |
| CD44 | CD44 molecule (Indian blood group) | 0.0227311 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0224692 |
| YEATS2 | YEATS domain containing 2 | 0.0223255 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0221412 |
| RAD21 | RAD21 homolog (S. pombe) | 0.022064 |
| ZNF148 | zinc finger protein 148 | 0.0219965 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0216538 |
| COPA | coatomer protein complex, subunit alpha | 0.0214406 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0214094 |
| ZNF654 | zinc finger protein 654 | 0.021247 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.021038 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0206328 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0205899 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0203106 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0202778 |
| AFAP1 | actin filament associated protein 1 | 0.0202274 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0201124 |
| TMF1 | TATA element modulatory factor 1 | 0.0198735 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0198096 |
| ASPH | aspartate beta-hydroxylase | 0.0196205 |
| ECT2 | epithelial cell transforming 2 | 0.019514 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0195106 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0194276 |
| CENPE | centromere protein E, 312kDa | 0.0193593 |
| TFG | TRK-fused gene | 0.0193185 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0192783 |
| GOLGB1 | golgin B1 | 0.019235 |
| CDK19 | cyclin-dependent kinase 19 | 0.0191139 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0190307 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0190164 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0189999 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0189175 |
| NAV2 | neuron navigator 2 | 0.0188916 |
| XPO1 | exportin 1 | 0.0186064 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0185256 |
| CDCP1 | CUB domain containing protein 1 | 0.0185047 |
| ZNF292 | zinc finger protein 292 | 0.0184358 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0180635 |
| KIF4A | kinesin family member 4A | 0.0180019 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0179293 |
| COG5 | component of oligomeric golgi complex 5 | 0.0178915 |
| SPAG9 | sperm associated antigen 9 | 0.0177042 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0174863 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0174152 |
| PRRC2C | proline-rich coiled-coil 2C | 0.017355 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0169484 |
| FNIP1 | folliculin interacting protein 1 | 0.0168873 |
| FOXJ3 | forkhead box J3 | 0.0168578 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0166138 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0164717 |
| MAP4 | microtubule-associated protein 4 | 0.0164643 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.016391 |
| SBF2 | SET binding factor 2 | 0.0162797 |
| NUMB | numb homolog (Drosophila) | 0.0162573 |
| OGA | O-GlcNAcase | 0.0161494 |
| NUP58 | nucleoporin 58 | 0.0161435 |
| NBEAL1 | neurobeachin-like 1 | 0.0160955 |
| RLIM | ring finger protein, LIM domain interacting | 0.0159948 |
| GPSM2 | G-protein signaling modulator 2 | 0.0159474 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0158801 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0158693 |
| SEC24D | SEC24 family member D | 0.0158351 |
| ATM | ATM serine/threonine kinase | 0.0158235 |
| TMEM39A | transmembrane protein 39A | 0.0158012 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0157288 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0157132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.107103 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0984532 |
| B2M | beta-2-microglobulin | -0.0982244 |
| COL1A1 | collagen, type I, alpha 1 | -0.0883482 |
| COL1A2 | collagen, type I, alpha 2 | -0.0757416 |
| TMSB10 | thymosin beta 10 | -0.071844 |
| FTL | ferritin, light polypeptide | -0.0704248 |
| CDH13 | cadherin 13 | -0.0654415 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0587682 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0536844 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0512116 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0511468 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0510654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504554 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0502853 |
| EGR1 | early growth response 1 | -0.0482597 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0449945 |
| HLA-A | major histocompatibility complex, class I, A | -0.0443891 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0431474 |
| VEGFA | vascular endothelial growth factor A | -0.0410703 |
| NAV1 | neuron navigator 1 | -0.0405635 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0356223 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0349556 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0334954 |
| CALR | calreticulin | -0.0331525 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0308984 |
| INHBA | inhibin, beta A | -0.030877 |
| LOXL2 | lysyl oxidase-like 2 | -0.0305063 |
| RPLP1 | ribosomal protein, large, P1 | -0.030284 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0296912 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0286223 |
| SP100 | SP100 nuclear antigen | -0.0279404 |
| HLA-C | major histocompatibility complex, class I, C | -0.0273811 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0270925 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0263658 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0263638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0260374 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0259186 |
| FRMD4A | FERM domain containing 4A | -0.025663 |
| STC1 | stanniocalcin 1 | -0.0252605 |
| NDRG1 | N-myc downstream regulated 1 | -0.0252314 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0251856 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0245346 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0244189 |
| MMP12 | matrix metallopeptidase 12 | -0.024005 |
| PTMA | prothymosin, alpha | -0.0238555 |
| COL5A3 | collagen, type V, alpha 3 | -0.0237238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0232714 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0231384 |
| CADM1 | cell adhesion molecule 1 | -0.0227592 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.022664 |
| IER3 | immediate early response 3 | -0.0226504 |
| RPL35A | ribosomal protein L35a | -0.0226419 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0225319 |
| HDAC9 | histone deacetylase 9 | -0.0214166 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0209238 |
| CST3 | cystatin C | -0.0209148 |
| S100A9 | S100 calcium binding protein A9 | -0.0209145 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.020733 |
| GLIS3 | GLIS family zinc finger 3 | -0.0206767 |
| RND3 | Rho family GTPase 3 | -0.0203139 |
| MMP2 | matrix metallopeptidase 2 | -0.0198461 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0198289 |
| IL1B | interleukin 1, beta | -0.0197084 |
| ECE1 | endothelin converting enzyme 1 | -0.0195971 |
| ADM | adrenomedullin | -0.0194537 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0194476 |
| CA12 | carbonic anhydrase XII | -0.019426 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0193805 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0193203 |
| C1R | complement component 1, r subcomponent | -0.0189968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0188895 |
| TGFB1 | transforming growth factor, beta 1 | -0.0188375 |
| RPS19 | ribosomal protein S19 | -0.0186902 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0185905 |
| FOSL1 | FOS-like antigen 1 | -0.017934 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0178888 |
| COL5A1 | collagen, type V, alpha 1 | -0.0178802 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0178096 |
| SEC61G | Sec61 gamma subunit | -0.0177851 |
| RPL28 | ribosomal protein L28 | -0.0176554 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0175656 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0173034 |
| RPS6 | ribosomal protein S6 | -0.0171073 |
| ANGPTL4 | angiopoietin-like 4 | -0.0169785 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0167437 |
| HLA-E | major histocompatibility complex, class I, E | -0.0166936 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0166789 |
| RIGI | RNA sensor RIG-I | -0.0165389 |
| RPL23 | ribosomal protein L23 | -0.0164727 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0164152 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0164005 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0160838 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0160164 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0159882 |
| TPM1 | tropomyosin 1 (alpha) | -0.0159786 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0158602 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0157582 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.015654 |
| S100A10 | S100 calcium binding protein A10 | -0.0155333 |
