| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.20982 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.168383 |
| FOXP1 | forkhead box P1 | 0.136151 |
| VCL | vinculin | 0.12318 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.117257 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.114284 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0959392 |
| NBEA | neurobeachin | 0.0864492 |
| PKM | pyruvate kinase, muscle | 0.0814459 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0804117 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0778756 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0678194 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0660219 |
| BMP10 | bone morphogenetic protein 10 | 0.0605807 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.059784 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.059374 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.057271 |
| TJP1 | tight junction protein 1 | 0.0565685 |
| EZR | ezrin | 0.0560407 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0559336 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0532951 |
| CD47 | CD47 molecule | 0.0530963 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0516085 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0508281 |
| ENO1 | enolase 1, (alpha) | 0.0494056 |
| PRELID2 | PRELI domain containing 2 | 0.0477496 |
| SMYD3 | SET and MYND domain containing 3 | 0.047527 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0468268 |
| EFNA5 | ephrin-A5 | 0.045267 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0448121 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0447498 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0439259 |
| NF1 | neurofibromin 1 | 0.0438702 |
| SBF2 | SET binding factor 2 | 0.0434499 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0429294 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0427336 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0423364 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0412091 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0397637 |
| FHIT | fragile histidine triad | 0.0383253 |
| PTK2 | protein tyrosine kinase 2 | 0.03682 |
| ATM | ATM serine/threonine kinase | 0.0361523 |
| BPTF | bromodomain PHD finger transcription factor | 0.036052 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.035838 |
| MACROD2 | MACRO domain containing 2 | 0.0358145 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357552 |
| TMSB4X | thymosin beta 4, X-linked | 0.0349926 |
| AHNAK | AHNAK nucleoprotein | 0.034877 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0344582 |
| EXOC6B | exocyst complex component 6B | 0.0341121 |
| GLI3 | GLI family zinc finger 3 | 0.0340546 |
| PDE10A | phosphodiesterase 10A | 0.0338013 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0330181 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0329809 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0327374 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0327265 |
| DUSP4 | dual specificity phosphatase 4 | 0.0327264 |
| CCND1 | cyclin D1 | 0.0325444 |
| APP | amyloid beta (A4) precursor protein | 0.0323833 |
| PGK1 | phosphoglycerate kinase 1 | 0.031896 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0312801 |
| DUSP6 | dual specificity phosphatase 6 | 0.031251 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0306635 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304665 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0304621 |
| LOXL3 | lysyl oxidase-like 3 | 0.0301124 |
| TCF12 | transcription factor 12 | 0.0298857 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0296694 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0291587 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0283385 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0283154 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.02827 |
| EXOC4 | exocyst complex component 4 | 0.0282498 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0281733 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0278902 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0278017 |
| CUX1 | cut-like homeobox 1 | 0.0277355 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0266642 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0265963 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.026537 |
| RBM26 | RNA binding motif protein 26 | 0.0263893 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0263461 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0262908 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0262139 |
| FAM13A | family with sequence similarity 13, member A | 0.0262061 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0259439 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0257449 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0257149 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0256013 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0254664 |
| ZNF609 | zinc finger protein 609 | 0.0254142 |
| ANKRD36 | ankyrin repeat domain 36 | 0.025076 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0250593 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0250405 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0249692 |
| TMEM135 | transmembrane protein 135 | 0.0248967 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0247969 |
| ASPH | aspartate beta-hydroxylase | 0.0247456 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0242649 |
| TAOK1 | TAO kinase 1 | 0.0239877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0965078 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0902545 |
| RPS6 | ribosomal protein S6 | -0.0733143 |
| RPLP1 | ribosomal protein, large, P1 | -0.0624907 |
| RPS19 | ribosomal protein S19 | -0.0607743 |
| RPS8 | ribosomal protein S8 | -0.0531938 |
| ANK2 | ankyrin 2, neuronal | -0.0499881 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0489266 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0488575 |
| RPLP2 | ribosomal protein, large, P2 | -0.048653 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0469771 |
| RPL12 | ribosomal protein L12 | -0.0463603 |
| RPL34 | ribosomal protein L34 | -0.0421405 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0390197 |
| RPS2 | ribosomal protein S2 | -0.0379464 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0375411 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0367472 |
| RPL35A | ribosomal protein L35a | -0.036098 |
| PTMA | prothymosin, alpha | -0.0355864 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0351586 |
| RPL13A | ribosomal protein L13a | -0.0342004 |
| RTN4 | reticulon 4 | -0.0340589 |
| RPL23 | ribosomal protein L23 | -0.0330737 |
| RPL26 | ribosomal protein L26 | -0.0325705 |
| RPL11 | ribosomal protein L11 | -0.0314195 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0307482 |
| ZNF644 | zinc finger protein 644 | -0.0303127 |
| RPS24 | ribosomal protein S24 | -0.0298032 |
| RPL7 | ribosomal protein L7 | -0.0295363 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0295126 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293513 |
| ACTG1 | actin gamma 1 | -0.0283345 |
| RPS23 | ribosomal protein S23 | -0.0280909 |
| GNAS | GNAS complex locus | -0.028 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0279441 |
| RPL36 | ribosomal protein L36 | -0.026987 |
| RPS12 | ribosomal protein S12 | -0.0264913 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0262454 |
| S100A10 | S100 calcium binding protein A10 | -0.0261662 |
| RPL19 | ribosomal protein L19 | -0.0257071 |
| DIAPH3 | diaphanous-related formin 3 | -0.0255942 |
| RPL9 | ribosomal protein L9 | -0.0249345 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0245229 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0244326 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0242759 |
| RPS21 | ribosomal protein S21 | -0.0237192 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0232378 |
| ZNF292 | zinc finger protein 292 | -0.022636 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0220267 |
| YBX1 | Y box binding protein 1 | -0.021748 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.021578 |
| RPL18 | ribosomal protein L18 | -0.0213689 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0210196 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0208858 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0205496 |
| RPL30 | ribosomal protein L30 | -0.0203976 |
| RPS25 | ribosomal protein S25 | -0.0202529 |
| RPS29 | ribosomal protein S29 | -0.0198694 |
| NCKAP1 | NCK-associated protein 1 | -0.019777 |
| WDR43 | WD repeat domain 43 | -0.0197448 |
| HMGB2 | high mobility group box 2 | -0.0190151 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0187745 |
| MT2A | metallothionein 2A | -0.0187669 |
| MEF2A | myocyte enhancer factor 2A | -0.0184361 |
| RPL27A | ribosomal protein L27a | -0.0180339 |
| S100A9 | S100 calcium binding protein A9 | -0.0178133 |
| ATP9B | ATPase, class II, type 9B | -0.0176406 |
| RPL28 | ribosomal protein L28 | -0.0175491 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0173239 |
| KLF6 | Kruppel-like factor 6 | -0.0167651 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0166943 |
| TFG | TRK-fused gene | -0.0166022 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0163554 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0162075 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0160296 |
| LDHA | lactate dehydrogenase A | -0.0159519 |
| HMGA1 | high mobility group AT-hook 1 | -0.0159379 |
| RPL8 | ribosomal protein L8 | -0.0158919 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0158293 |
| RPS20 | ribosomal protein S20 | -0.0155784 |
| RPL38 | ribosomal protein L38 | -0.0155507 |
| RACK1 | receptor for activated C kinase 1 | -0.0154799 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0153727 |
| RPS27 | ribosomal protein S27 | -0.0153465 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0152175 |
| S100A6 | S100 calcium binding protein A6 | -0.0151851 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0151543 |
| RPL31 | ribosomal protein L31 | -0.015153 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0151331 |
| NOP58 | NOP58 ribonucleoprotein | -0.0151315 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0150662 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0150006 |
| ATF4 | activating transcription factor 4 | -0.0149619 |
| TOP1 | topoisomerase (DNA) I | -0.0148904 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0148115 |
| STK40 | serine/threonine kinase 40 | -0.0147188 |
| RPL4 | ribosomal protein L4 | -0.0147 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0146935 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0146805 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0146595 |
