| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.143809 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.11103 |
| VCAN | versican | 0.0825263 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0731349 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0720723 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0682473 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.062622 |
| GLIS3 | GLIS family zinc finger 3 | 0.0618792 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0609321 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0594906 |
| VIM | vimentin | 0.0553759 |
| PGK1 | phosphoglycerate kinase 1 | 0.0484994 |
| CADM1 | cell adhesion molecule 1 | 0.0480056 |
| PDE10A | phosphodiesterase 10A | 0.0470352 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0454657 |
| ANXA2 | annexin A2 | 0.0444491 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0432043 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0431608 |
| LDHA | lactate dehydrogenase A | 0.0430923 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0421438 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0412148 |
| ATP13A3 | ATPase type 13A3 | 0.0411166 |
| CDK19 | cyclin-dependent kinase 19 | 0.0381442 |
| FNIP1 | folliculin interacting protein 1 | 0.0375173 |
| PHF21A | PHD finger protein 21A | 0.0372419 |
| DIAPH2 | diaphanous-related formin 2 | 0.0366319 |
| RND3 | Rho family GTPase 3 | 0.036561 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0347158 |
| SFTPA2 | surfactant protein A2 | 0.0346354 |
| ATXN1 | ataxin 1 | 0.0344592 |
| HELZ | helicase with zinc finger | 0.0339709 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0332383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.032753 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0320091 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0310407 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0306946 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0295616 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0281713 |
| MAP4 | microtubule-associated protein 4 | 0.0278787 |
| CANX | calnexin | 0.0278286 |
| EHBP1 | EH domain binding protein 1 | 0.027329 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0265762 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0265583 |
| ANXA1 | annexin A1 | 0.0265075 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0263088 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0261967 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0259908 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0257257 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0256454 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0255673 |
| RAI14 | retinoic acid induced 14 | 0.0255146 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.025489 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0251298 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0251226 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0249303 |
| OGA | O-GlcNAcase | 0.0247976 |
| KIF13A | kinesin family member 13A | 0.0245548 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0244287 |
| USP34 | ubiquitin specific peptidase 34 | 0.0242325 |
| MORF4L2 | mortality factor 4 like 2 | 0.0240933 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0238991 |
| BBX | bobby sox homolog (Drosophila) | 0.0238005 |
| PCBP2 | poly(rC) binding protein 2 | 0.023373 |
| THOC2 | THO complex 2 | 0.0232895 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0231065 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0229846 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0229687 |
| JUN | jun proto-oncogene | 0.0226405 |
| PTK2 | protein tyrosine kinase 2 | 0.0221891 |
| STAG2 | stromal antigen 2 | 0.0217663 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0216759 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0215996 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0215903 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0212367 |
| DST | dystonin | 0.0211492 |
| NF1 | neurofibromin 1 | 0.0209897 |
| CDH13 | cadherin 13 | 0.0208343 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0207762 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0204456 |
| GOLGB1 | golgin B1 | 0.0203934 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0201463 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0198807 |
| HMGA2 | high mobility group AT-hook 2 | 0.0198123 |
| FBXO32 | F-box protein 32 | 0.0198019 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0196594 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0196433 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0193165 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0191896 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0190826 |
| SDCBP | syndecan binding protein (syntenin) | 0.0190581 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0190338 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0189844 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0189288 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0189114 |
| FNBP4 | formin binding protein 4 | 0.0188318 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0187589 |
| LRRC7 | leucine rich repeat containing 7 | 0.0186992 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0186317 |
| SNX3 | sorting nexin 3 | 0.0185094 |
| ZNF451 | zinc finger protein 451 | 0.0184928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141013 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0917832 |
| MT2A | metallothionein 2A | -0.0806507 |
| HLA-B | major histocompatibility complex, class I, B | -0.0764097 |
| FTL | ferritin, light polypeptide | -0.0647567 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0613581 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0601878 |
| VCL | vinculin | -0.055705 |
| TMSB10 | thymosin beta 10 | -0.0536002 |
| RPS12 | ribosomal protein S12 | -0.0497532 |
| RPLP2 | ribosomal protein, large, P2 | -0.0496567 |
| RPS6 | ribosomal protein S6 | -0.0495493 |
| RPL23 | ribosomal protein L23 | -0.0479367 |
| RPS2 | ribosomal protein S2 | -0.0477551 |
| KYNU | kynureninase | -0.0467156 |
| RPL37A | ribosomal protein L37a | -0.0436681 |
| IER3 | immediate early response 3 | -0.0418663 |
| RPS8 | ribosomal protein S8 | -0.0416532 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.040833 |
| RPLP1 | ribosomal protein, large, P1 | -0.0400016 |
| PTMA | prothymosin, alpha | -0.0398336 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0380975 |
| RPL9 | ribosomal protein L9 | -0.0372215 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.035844 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0314852 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0312167 |
| RPL19 | ribosomal protein L19 | -0.031191 |
| RPS24 | ribosomal protein S24 | -0.0307654 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0305245 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.029649 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0284404 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0283581 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0277346 |
| RPL26 | ribosomal protein L26 | -0.0275531 |
| RPL35 | ribosomal protein L35 | -0.0274869 |
| RPS25 | ribosomal protein S25 | -0.0274417 |
| RPL36 | ribosomal protein L36 | -0.0271537 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0269559 |
| NAV2 | neuron navigator 2 | -0.0266106 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0263657 |
| RTN4 | reticulon 4 | -0.026164 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0260529 |
| RPL38 | ribosomal protein L38 | -0.0256291 |
| RPS19 | ribosomal protein S19 | -0.0253581 |
| RPL35A | ribosomal protein L35a | -0.0247326 |
| RPS27A | ribosomal protein S27a | -0.0245729 |
| RPL36A | ribosomal protein L36a | -0.0243711 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0237892 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0237272 |
| RPS23 | ribosomal protein S23 | -0.0232844 |
| S100A9 | S100 calcium binding protein A9 | -0.0230362 |
| PALLD | palladin, cytoskeletal associated protein | -0.0228888 |
| RPS10 | ribosomal protein S10 | -0.022497 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0223635 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0220504 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.021734 |
| RPS29 | ribosomal protein S29 | -0.0215972 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0215739 |
| C3 | complement component 3 | -0.0214016 |
| RPL31 | ribosomal protein L31 | -0.0212846 |
| RPL11 | ribosomal protein L11 | -0.0212631 |
| RPL27A | ribosomal protein L27a | -0.0212497 |
| B2M | beta-2-microglobulin | -0.0207251 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0205443 |
| RPL34 | ribosomal protein L34 | -0.0203959 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0202706 |
| OSMR | oncostatin M receptor | -0.0198825 |
| RPL27 | ribosomal protein L27 | -0.0198825 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0195351 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0192706 |
| RPS21 | ribosomal protein S21 | -0.0192309 |
| PLPP3 | phospholipid phosphatase 3 | -0.0191064 |
| RPS14 | ribosomal protein S14 | -0.0188353 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0187284 |
| RPL37 | ribosomal protein L37 | -0.0185232 |
| DUSP5 | dual specificity phosphatase 5 | -0.0184707 |
| NABP1 | nucleic acid binding protein 1 | -0.0184395 |
| CALD1 | caldesmon 1 | -0.0183122 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0181525 |
| RPS13 | ribosomal protein S13 | -0.0180516 |
| CD44 | CD44 molecule (Indian blood group) | -0.0179961 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0177401 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0175685 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0173509 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0172154 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0171647 |
| ACTN1 | actinin, alpha 1 | -0.0171284 |
| RPL8 | ribosomal protein L8 | -0.0170849 |
| SYAP1 | synapse associated protein 1 | -0.0170369 |
| FLOT1 | flotillin 1 | -0.0169082 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0168763 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0168698 |
| SPAG9 | sperm associated antigen 9 | -0.0168073 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0167764 |
| RPL28 | ribosomal protein L28 | -0.0167064 |
| RPL12 | ribosomal protein L12 | -0.0163476 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0162963 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.016147 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0160616 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0158859 |
