| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0855584 |
| CD44 | CD44 molecule (Indian blood group) | 0.0679931 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0547819 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0530272 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0472894 |
| NRXN3 | neurexin 3 | 0.0469596 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0466357 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0456853 |
| ANXA2 | annexin A2 | 0.0438552 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0435557 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0419728 |
| SBF2 | SET binding factor 2 | 0.0413494 |
| DST | dystonin | 0.0395351 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0381589 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0368629 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0365206 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0352527 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0335875 |
| EPAS1 | endothelial PAS domain protein 1 | 0.032357 |
| GLIS3 | GLIS family zinc finger 3 | 0.0318069 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0316857 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0311841 |
| ANKRD11 | ankyrin repeat domain 11 | 0.030835 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0293304 |
| MYOF | myoferlin | 0.0290927 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0288238 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0285692 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283698 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0283597 |
| PARD3 | par-3 family cell polarity regulator | 0.0282212 |
| ITGA6 | integrin, alpha 6 | 0.0280633 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0280556 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0279806 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278934 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0274915 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.027436 |
| TANK | TRAF family member-associated NFKB activator | 0.0268192 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0266951 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0259525 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0258671 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0258233 |
| FOXJ3 | forkhead box J3 | 0.0257862 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.025751 |
| URI1 | URI1, prefoldin-like chaperone | 0.0257031 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0256627 |
| YME1L1 | YME1-like 1 ATPase | 0.0255891 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0255712 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0255511 |
| NAV1 | neuron navigator 1 | 0.0254091 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0251865 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0250421 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0247406 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0246015 |
| AK1 | adenylate kinase 1 | 0.0244455 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0243325 |
| PTK2 | protein tyrosine kinase 2 | 0.0242625 |
| TNNC1 | troponin C type 1 (slow) | 0.024182 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0238647 |
| RBM39 | RNA binding motif protein 39 | 0.0238623 |
| ACER3 | alkaline ceramidase 3 | 0.0237932 |
| SLMAP | sarcolemma associated protein | 0.0236921 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0235898 |
| EMP1 | epithelial membrane protein 1 | 0.0235823 |
| HM13 | histocompatibility (minor) 13 | 0.0234142 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0233923 |
| FAM13B | family with sequence similarity 13, member B | 0.0233316 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0231284 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0230083 |
| MEF2A | myocyte enhancer factor 2A | 0.0228633 |
| PCNX1 | pecanex 1 | 0.02279 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0226435 |
| EREG | epiregulin | 0.0226241 |
| COG5 | component of oligomeric golgi complex 5 | 0.0225693 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0225295 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0224474 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0224041 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0223685 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0223317 |
| VMP1 | vacuole membrane protein 1 | 0.0223025 |
| EGR1 | early growth response 1 | 0.0222651 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0222489 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0221799 |
| FMNL2 | formin-like 2 | 0.02206 |
| ERBIN | erbb2 interacting protein | 0.021919 |
| LAMB1 | laminin, beta 1 | 0.0219066 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0218289 |
| AHR | aryl hydrocarbon receptor | 0.0218261 |
| OXR1 | oxidation resistance 1 | 0.0216496 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0214348 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0213949 |
| TCERG1 | transcription elongation regulator 1 | 0.0213285 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0211638 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0211158 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0210704 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0209443 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0208881 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0208151 |
| FRMD6 | FERM domain containing 6 | 0.020792 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0207709 |
| RNF145 | ring finger protein 145 | 0.0207579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.210347 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.174872 |
| VIM | vimentin | -0.125283 |
| UBC | ubiquitin C | -0.11177 |
| MT2A | metallothionein 2A | -0.102309 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0879223 |
| B2M | beta-2-microglobulin | -0.0863641 |
| COL1A2 | collagen, type I, alpha 2 | -0.0844322 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0833575 |
| HLA-B | major histocompatibility complex, class I, B | -0.079511 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0793215 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0786753 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0772271 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0762894 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0710934 |
| ENO1 | enolase 1, (alpha) | -0.069443 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0689845 |
| SDC4 | syndecan 4 | -0.068761 |
| IL6 | interleukin 6 | -0.0671245 |
| CALU | calumenin | -0.0663466 |
| CCNI | cyclin I | -0.0654154 |
| AHNAK | AHNAK nucleoprotein | -0.0607704 |
| POTEF | POTE ankyrin domain family, member F | -0.0603261 |
| COL1A1 | collagen, type I, alpha 1 | -0.0597453 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0579859 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0571808 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.050946 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0495413 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.048608 |
| TXNIP | thioredoxin interacting protein | -0.0478725 |
| LOX | lysyl oxidase | -0.0473254 |
| PTMA | prothymosin, alpha | -0.0444479 |
| CANX | calnexin | -0.0437697 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0423016 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0420286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0416397 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0411398 |
| CDK13 | cyclin-dependent kinase 13 | -0.0400471 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0393625 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0387475 |
| FTL | ferritin, light polypeptide | -0.0383098 |
| SEPTIN7 | septin 7 | -0.0375984 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0372034 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0368071 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0366939 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0366215 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0361532 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0361357 |
| HDLBP | high density lipoprotein binding protein | -0.0356578 |
| ACTG1 | actin gamma 1 | -0.0354489 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0352934 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0351369 |
| MAP1B | microtubule-associated protein 1B | -0.0349748 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0345707 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0345412 |
| SPAG9 | sperm associated antigen 9 | -0.0341957 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0340511 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0339229 |
| CALR | calreticulin | -0.0335608 |
| TMEM165 | transmembrane protein 165 | -0.0329903 |
| S100A10 | S100 calcium binding protein A10 | -0.0329518 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0327264 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0325514 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0322204 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0314691 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0307339 |
| HMGB2 | high mobility group box 2 | -0.0305079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0303798 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0302397 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0298911 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0296948 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0294557 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0294504 |
| PGK1 | phosphoglycerate kinase 1 | -0.0294459 |
| LDHA | lactate dehydrogenase A | -0.0292535 |
| SRPK2 | SRSF protein kinase 2 | -0.0291412 |
| WTAP | Wilms tumor 1 associated protein | -0.0289408 |
| JUN | jun proto-oncogene | -0.0286824 |
| PRRC1 | proline-rich coiled-coil 1 | -0.028546 |
| SEC61G | Sec61 gamma subunit | -0.0285104 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0284411 |
| MT1X | metallothionein 1X | -0.0281656 |
| PTGES2 | prostaglandin E synthase 2 | -0.0280199 |
| FLNB | filamin B, beta | -0.027993 |
| GANAB | glucosidase, alpha; neutral AB | -0.027959 |
| ZNF292 | zinc finger protein 292 | -0.0278213 |
| RPS11 | ribosomal protein S11 | -0.0276719 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0275048 |
| MTPN | myotrophin | -0.0274722 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0273443 |
| GRN | granulin | -0.0270051 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0269524 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0267344 |
| RPL37A | ribosomal protein L37a | -0.0266815 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0266636 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0263795 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0262961 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0259283 |
| COL5A2 | collagen, type V, alpha 2 | -0.0259021 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0258323 |
