| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0588514 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0376059 |
| TPX2 | TPX2, microtubule-associated | 0.0331236 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0294637 |
| ANXA1 | annexin A1 | 0.0286451 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0281985 |
| SEC24A | SEC24 family member A | 0.0276972 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0271956 |
| CENPF | centromere protein F, 350/400kDa | 0.0266844 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0260016 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0259951 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0246107 |
| NUP58 | nucleoporin 58 | 0.023651 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0236146 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0233954 |
| TXNRD1 | thioredoxin reductase 1 | 0.0229146 |
| SGO2 | shugoshin 2 | 0.0228685 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0220951 |
| PNN | pinin, desmosome associated protein | 0.021748 |
| GOLGA4 | golgin A4 | 0.0215744 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0215643 |
| RBM39 | RNA binding motif protein 39 | 0.0215308 |
| ARF4 | ADP-ribosylation factor 4 | 0.0211615 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0204927 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.020447 |
| GOLT1B | golgi transport 1B | 0.0198462 |
| ECT2 | epithelial cell transforming 2 | 0.0197507 |
| ANLN | anillin, actin binding protein | 0.0194041 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0194 |
| GOLGB1 | golgin B1 | 0.0189012 |
| KIF5B | kinesin family member 5B | 0.018781 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0184909 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0181611 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0180299 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0176565 |
| MKI67 | marker of proliferation Ki-67 | 0.0171185 |
| QKI | QKI, KH domain containing, RNA binding | 0.0169615 |
| CUL3 | cullin 3 | 0.0168415 |
| FNIP1 | folliculin interacting protein 1 | 0.0168272 |
| GOLGA2 | golgin A2 | 0.0166955 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0165861 |
| NUP153 | nucleoporin 153kDa | 0.016262 |
| JMJD1C | jumonji domain containing 1C | 0.0162475 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0162268 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0159256 |
| SETD5 | SET domain containing 5 | 0.0159073 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0158175 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0157485 |
| YBX3 | Y box binding protein 3 | 0.0156608 |
| CENPE | centromere protein E, 312kDa | 0.0155797 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0155453 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0153982 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0153142 |
| NKTR | natural killer cell triggering receptor | 0.0152302 |
| FRYL | FRY-like | 0.0151754 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0151731 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.0151592 |
| OLA1 | Obg-like ATPase 1 | 0.01504 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.015003 |
| FAM13A | family with sequence similarity 13, member A | 0.0149268 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0148866 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0147983 |
| YAP1 | Yes-associated protein 1 | 0.0147899 |
| CEP70 | centrosomal protein 70kDa | 0.0147518 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0147085 |
| NGLY1 | N-glycanase 1 | 0.0146338 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0146266 |
| SPAG5 | sperm associated antigen 5 | 0.0143578 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0143471 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0142776 |
| COG6 | component of oligomeric golgi complex 6 | 0.0141875 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0141211 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0139731 |
| UBE3A | ubiquitin protein ligase E3A | 0.0139054 |
| CCDC88A | coiled-coil domain containing 88A | 0.0137821 |
| NCKAP1 | NCK-associated protein 1 | 0.0137502 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0137065 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0135722 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0135523 |
| SRP54 | signal recognition particle 54kDa | 0.0135316 |
| RDX | radixin | 0.0135227 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0135143 |
| SPPL3 | signal peptide peptidase like 3 | 0.0133839 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0133283 |
| CDC73 | cell division cycle 73 | 0.0132155 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0131854 |
| RPS2 | ribosomal protein S2 | 0.0131618 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0131536 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0131445 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.013077 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0129836 |
| KIF23 | kinesin family member 23 | 0.0129821 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0128416 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0128234 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0127951 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0125634 |
| SRPK2 | SRSF protein kinase 2 | 0.0123996 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0123039 |
| AURKA | aurora kinase A | 0.0123011 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.012203 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.147791 |
| TMSB10 | thymosin beta 10 | -0.117969 |
| VIM | vimentin | -0.0973127 |
| CD44 | CD44 molecule (Indian blood group) | -0.0862287 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0743023 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0650576 |
| AHNAK | AHNAK nucleoprotein | -0.060991 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0587329 |
| HMGA2 | high mobility group AT-hook 2 | -0.0585407 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0546954 |
| PKM | pyruvate kinase, muscle | -0.0518025 |
| PTMA | prothymosin, alpha | -0.0464722 |
| ANGPTL4 | angiopoietin-like 4 | -0.0459252 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0451179 |
| UBC | ubiquitin C | -0.0441059 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0404568 |
| POTEF | POTE ankyrin domain family, member F | -0.0404548 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0398981 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0397065 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0395487 |
| OSMR | oncostatin M receptor | -0.0387611 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0382818 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0371756 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0368596 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0359418 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0359246 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0357224 |
| DST | dystonin | -0.0344518 |
| SDC4 | syndecan 4 | -0.0344376 |
| PRSS23 | protease, serine, 23 | -0.0343676 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0342504 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0340589 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0339637 |
| FMNL2 | formin-like 2 | -0.0333606 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0320556 |
| RPS27A | ribosomal protein S27a | -0.0319676 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0319439 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0311105 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0310641 |
| ATXN1 | ataxin 1 | -0.0300936 |
| RPS13 | ribosomal protein S13 | -0.0294991 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0288765 |
| SVIL | supervillin | -0.028366 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0282971 |
| FLNB | filamin B, beta | -0.0280463 |
| ENO1 | enolase 1, (alpha) | -0.0279972 |
| S100A10 | S100 calcium binding protein A10 | -0.0274456 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.027425 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.026417 |
| PRKCA | protein kinase C, alpha | -0.0263399 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.026093 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0255193 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0248619 |
| EFNA5 | ephrin-A5 | -0.0245543 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0244931 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0241514 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0237517 |
| H3-3B | H3.3 histone B | -0.0236932 |
| ACTG1 | actin gamma 1 | -0.023302 |
| PGK1 | phosphoglycerate kinase 1 | -0.022982 |
| PTK2 | protein tyrosine kinase 2 | -0.0229792 |
| RPL35A | ribosomal protein L35a | -0.0229055 |
| MCL1 | myeloid cell leukemia 1 | -0.0227479 |
| RAI14 | retinoic acid induced 14 | -0.0226824 |
| TPI1 | triosephosphate isomerase 1 | -0.0226323 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224959 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0223823 |
| RPS8 | ribosomal protein S8 | -0.0223517 |
| RPLP2 | ribosomal protein, large, P2 | -0.0222703 |
| RPL23 | ribosomal protein L23 | -0.0221659 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.02203 |
| RNF213 | ring finger protein 213 | -0.0219734 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0218416 |
| RPL37 | ribosomal protein L37 | -0.021673 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0215503 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0214813 |
| RAD51B | RAD51 paralog B | -0.0212124 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.021172 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0209116 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0209039 |
| PRR16 | proline rich 16 | -0.0207227 |
| IER3 | immediate early response 3 | -0.0205163 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0203136 |
| TRIM56 | tripartite motif containing 56 | -0.0201552 |
| RPL27A | ribosomal protein L27a | -0.0199822 |
| GNAS | GNAS complex locus | -0.019979 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0199317 |
| VCL | vinculin | -0.0199156 |
| PRRC2B | proline-rich coiled-coil 2B | -0.019797 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0197156 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0197025 |
| S100A9 | S100 calcium binding protein A9 | -0.0194996 |
| IGF2 | insulin-like growth factor 2 | -0.0194141 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0192202 |
| TPM4 | tropomyosin 4 | -0.0191688 |
| PLEK2 | pleckstrin 2 | -0.0191601 |
| NLK | nemo-like kinase | -0.0189371 |
| FMN1 | formin 1 | -0.0186948 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0185364 |
| RIGI | RNA sensor RIG-I | -0.0183804 |
