| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.185113 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.115583 |
| FN1 | fibronectin 1 | 0.0939862 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0800194 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0790291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0613043 |
| CANX | calnexin | 0.053285 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0525352 |
| ITGA1 | integrin, alpha 1 | 0.0486142 |
| GLIS3 | GLIS family zinc finger 3 | 0.0472099 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0431422 |
| AHR | aryl hydrocarbon receptor | 0.042862 |
| TPR | translocated promoter region, nuclear basket protein | 0.0427184 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0410848 |
| TMEM156 | transmembrane protein 156 | 0.0384753 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0328096 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0326911 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0303651 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0297342 |
| EREG | epiregulin | 0.0283127 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0276871 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0276493 |
| SUCO | SUN domain containing ossification factor | 0.0276034 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0271291 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.026671 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0264759 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0259148 |
| SYT1 | synaptotagmin I | 0.0255985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025276 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0248117 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0241999 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0240172 |
| RAI14 | retinoic acid induced 14 | 0.0239995 |
| ASPH | aspartate beta-hydroxylase | 0.0239807 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0239344 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0235664 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0233154 |
| CLTC | clathrin, heavy chain (Hc) | 0.0227461 |
| DST | dystonin | 0.0227353 |
| AOPEP | aminopeptidase O (putative) | 0.0226116 |
| H1-0 | H1.0 linker histone | 0.0222055 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0221677 |
| ETV6 | ets variant 6 | 0.0216423 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0213573 |
| GOLT1B | golgi transport 1B | 0.0212066 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0211668 |
| SMAD3 | SMAD family member 3 | 0.0210311 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0208462 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0207575 |
| OSMR | oncostatin M receptor | 0.0202542 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0197507 |
| DENND5B | DENN/MADD domain containing 5B | 0.0195657 |
| CLINT1 | clathrin interactor 1 | 0.019519 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0192216 |
| SMYD3 | SET and MYND domain containing 3 | 0.0192125 |
| NRG1 | neuregulin 1 | 0.018973 |
| TMSB4X | thymosin beta 4, X-linked | 0.0189699 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0187414 |
| YBX3 | Y box binding protein 3 | 0.0187114 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0185294 |
| OGA | O-GlcNAcase | 0.018494 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0183333 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0180963 |
| ETNK1 | ethanolamine kinase 1 | 0.0179757 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0179735 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0177259 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0176096 |
| NEK7 | NIMA-related kinase 7 | 0.0175839 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0175419 |
| APP | amyloid beta (A4) precursor protein | 0.0175306 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0172319 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0171791 |
| LMNA | lamin A/C | 0.0171471 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.016998 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0169939 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0169934 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0168653 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0167835 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0167329 |
| ARF1 | ADP-ribosylation factor 1 | 0.0164969 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0164639 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0164556 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0162918 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0162906 |
| CDC73 | cell division cycle 73 | 0.0162281 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0161579 |
| RANBP17 | RAN binding protein 17 | 0.0161493 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0161294 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0160651 |
| HMGA2 | high mobility group AT-hook 2 | 0.0160539 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0160438 |
| HDLBP | high density lipoprotein binding protein | 0.0159643 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0159618 |
| NRP1 | neuropilin 1 | 0.0158983 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0158427 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0157503 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0156597 |
| FNBP1 | formin binding protein 1 | 0.0154586 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0154518 |
| VEGFC | vascular endothelial growth factor C | 0.0153583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14799 |
| NDRG1 | N-myc downstream regulated 1 | -0.0757261 |
| VIM | vimentin | -0.064013 |
| PTMA | prothymosin, alpha | -0.0638738 |
| FTL | ferritin, light polypeptide | -0.0626834 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0542851 |
| TMSB10 | thymosin beta 10 | -0.0526676 |
| MT2A | metallothionein 2A | -0.0522418 |
| RPS6 | ribosomal protein S6 | -0.0516232 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0472575 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0439098 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414298 |
| PLIN2 | perilipin 2 | -0.0407751 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0392009 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0379727 |
| RPL35A | ribosomal protein L35a | -0.0377417 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347625 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0335902 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0329004 |
| RPL37A | ribosomal protein L37a | -0.0318462 |
| RPL9 | ribosomal protein L9 | -0.0299439 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0297965 |
| ACTG1 | actin gamma 1 | -0.0292982 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0291517 |
| RPS8 | ribosomal protein S8 | -0.0290218 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0286008 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0281193 |
| HLA-B | major histocompatibility complex, class I, B | -0.0273551 |
| RPS12 | ribosomal protein S12 | -0.0270821 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0262488 |
| FOSL1 | FOS-like antigen 1 | -0.0256315 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0255195 |
| B2M | beta-2-microglobulin | -0.0246919 |
| HMGA1 | high mobility group AT-hook 1 | -0.0243925 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0238453 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0229968 |
| RPL23 | ribosomal protein L23 | -0.0226779 |
| RPL12 | ribosomal protein L12 | -0.0225415 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224865 |
| RPL31 | ribosomal protein L31 | -0.0222083 |
| RPS25 | ribosomal protein S25 | -0.0219352 |
| RPL37 | ribosomal protein L37 | -0.0218482 |
| PKM | pyruvate kinase, muscle | -0.0212942 |
| RPLP2 | ribosomal protein, large, P2 | -0.0201504 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0200133 |
| RTN4 | reticulon 4 | -0.0196829 |
| EGR1 | early growth response 1 | -0.0193577 |
| POTEF | POTE ankyrin domain family, member F | -0.0193288 |
| RPS16 | ribosomal protein S16 | -0.0190905 |
| RPS23 | ribosomal protein S23 | -0.0190822 |
| RPS11 | ribosomal protein S11 | -0.0181368 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0178368 |
| RPS14 | ribosomal protein S14 | -0.0174029 |
| RPS29 | ribosomal protein S29 | -0.0173984 |
| S100A6 | S100 calcium binding protein A6 | -0.0173426 |
| PFN1 | profilin 1 | -0.0172181 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0169882 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0169238 |
| RPS3 | ribosomal protein S3 | -0.0164422 |
| ENO1 | enolase 1, (alpha) | -0.0163925 |
| FLNB | filamin B, beta | -0.0163458 |
| RPS27 | ribosomal protein S27 | -0.0163052 |
| TPM4 | tropomyosin 4 | -0.016143 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.016096 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0160831 |
| STC2 | stanniocalcin 2 | -0.0158913 |
| RPS19 | ribosomal protein S19 | -0.0158101 |
| RPS17 | ribosomal protein S17 | -0.0157333 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0156331 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0151022 |
| RPS13 | ribosomal protein S13 | -0.014916 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0148799 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.014826 |
| STC1 | stanniocalcin 1 | -0.0148072 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0147391 |
| RPS24 | ribosomal protein S24 | -0.01472 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0146791 |
| RPL36 | ribosomal protein L36 | -0.0146645 |
| RPL28 | ribosomal protein L28 | -0.0146569 |
| S100A10 | S100 calcium binding protein A10 | -0.0145468 |
| RPL34 | ribosomal protein L34 | -0.0143316 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0141711 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0138542 |
| RPL8 | ribosomal protein L8 | -0.0136689 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.013664 |
| RPLP0 | ribosomal protein, large, P0 | -0.0136632 |
| SEPTIN7 | septin 7 | -0.0133589 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0133508 |
| CTSD | cathepsin D | -0.0131618 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0130234 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0130051 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0128381 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0127062 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0126846 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0126484 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0125395 |
| INTS6 | integrator complex subunit 6 | -0.0124647 |
| CALD1 | caldesmon 1 | -0.0123544 |
| HLA-A | major histocompatibility complex, class I, A | -0.0123248 |
| RACK1 | receptor for activated C kinase 1 | -0.012181 |
