| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0747914 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0651986 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0428365 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0416618 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0309285 |
| TXNIP | thioredoxin interacting protein | 0.0286203 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0269715 |
| LMTK2 | lemur tyrosine kinase 2 | 0.026423 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0232572 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0222687 |
| TMEM106B | transmembrane protein 106B | 0.0204089 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.019645 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0194232 |
| SP3 | Sp3 transcription factor | 0.0192222 |
| TXNRD1 | thioredoxin reductase 1 | 0.0189955 |
| SNX9 | sorting nexin 9 | 0.0187997 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0185819 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0170562 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0170423 |
| PTEN | phosphatase and tensin homolog | 0.0170233 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0169709 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0169699 |
| ZNF148 | zinc finger protein 148 | 0.0166699 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.0163863 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0161522 |
| CLDN4 | claudin 4 | 0.0159431 |
| ZFP36 | ZFP36 ring finger protein | 0.0159295 |
| NEBL | nebulette | 0.0157941 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0153809 |
| ERBIN | erbb2 interacting protein | 0.0152452 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0152267 |
| ETV6 | ets variant 6 | 0.014895 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0145918 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0144556 |
| KRT80 | keratin 80, type II | 0.0144045 |
| CENPF | centromere protein F, 350/400kDa | 0.0134786 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0133917 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0133516 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0132644 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.0132513 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0131934 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0130529 |
| SMYD3 | SET and MYND domain containing 3 | 0.0129964 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0128843 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0126103 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0125453 |
| POTEF | POTE ankyrin domain family, member F | 0.0125414 |
| VMP1 | vacuole membrane protein 1 | 0.012513 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0123211 |
| FAM3C | family with sequence similarity 3, member C | 0.012259 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0120058 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.011991 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0118856 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0117096 |
| PLAUR | plasminogen activator, urokinase receptor | 0.011638 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0115837 |
| USP47 | ubiquitin specific peptidase 47 | 0.0115832 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0115807 |
| MKRN1 | makorin ring finger protein 1 | 0.0115737 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0115478 |
| ANKRD12 | ankyrin repeat domain 12 | 0.011547 |
| UBE3A | ubiquitin protein ligase E3A | 0.0114535 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0113457 |
| RPL21 | ribosomal protein L21 | 0.0112791 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0112033 |
| MYOF | myoferlin | 0.0112006 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0111688 |
| TNS3 | tensin 3 | 0.0110812 |
| SYK | spleen tyrosine kinase | 0.0110004 |
| IL18 | interleukin 18 | 0.0107749 |
| GPSM2 | G-protein signaling modulator 2 | 0.010773 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0107401 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0106731 |
| ATG5 | autophagy related 5 | 0.0106368 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0106007 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0105901 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0105521 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0104935 |
| SECISBP2 | SECIS binding protein 2 | 0.0104731 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0103978 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0103639 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0103507 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0102848 |
| GTPBP10 | GTP-binding protein 10 (putative) | 0.0101814 |
| LATS2 | large tumor suppressor kinase 2 | 0.0101725 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0101562 |
| CLDN3 | claudin 3 | 0.0101025 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0100452 |
| MEF2A | myocyte enhancer factor 2A | 0.0100413 |
| AXIN2 | axin 2 | 0.00998361 |
| KIAA1217 | KIAA1217 | 0.00990811 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.00975303 |
| RBM12 | RNA binding motif protein 12 | 0.00970664 |
| MTMR3 | myotubularin related protein 3 | 0.00968575 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00965995 |
| UBXN4 | UBX domain protein 4 | 0.00962255 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.00961109 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00959773 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00956722 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.00953401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.149642 |
| IFRD1 | interferon-related developmental regulator 1 | -0.100022 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0973129 |
| EZR | ezrin | -0.0933672 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0842355 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0838815 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0835956 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0747603 |
| TMSB10 | thymosin beta 10 | -0.0726212 |
| GNAS | GNAS complex locus | -0.0697828 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0684927 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0653462 |
| NDRG1 | N-myc downstream regulated 1 | -0.064391 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0636487 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0633509 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0598262 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0589659 |
| PGK1 | phosphoglycerate kinase 1 | -0.0582806 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0580457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0562027 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0542728 |
| VCL | vinculin | -0.051341 |
| CANX | calnexin | -0.0508207 |
| AHNAK | AHNAK nucleoprotein | -0.0489473 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.047944 |
| INTS6 | integrator complex subunit 6 | -0.0475237 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0429636 |
| PKM | pyruvate kinase, muscle | -0.0428534 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0410002 |
| FTL | ferritin, light polypeptide | -0.0403288 |
| NFIA | nuclear factor I/A | -0.0399354 |
| MSI2 | musashi RNA-binding protein 2 | -0.0391665 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0385711 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0385524 |
| IER3 | immediate early response 3 | -0.0383211 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.03793 |
| SERINC5 | serine incorporator 5 | -0.0376535 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0375435 |
| KRT18 | keratin 18, type I | -0.0373881 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0369825 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0363596 |
| RPS24 | ribosomal protein S24 | -0.0361351 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0356897 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0355336 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0350469 |
| TPM4 | tropomyosin 4 | -0.0339987 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0339357 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0337481 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0332182 |
| RTN3 | reticulon 3 | -0.0331572 |
| SQSTM1 | sequestosome 1 | -0.0330139 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0330061 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0324736 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0322924 |
| EPCAM | epithelial cell adhesion molecule | -0.0321173 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0306423 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0304661 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0302764 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0301241 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0300481 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0299541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0296705 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0296099 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0295476 |
| FBXO11 | F-box protein 11 | -0.0295336 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293179 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0293139 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0287093 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0286203 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0283758 |
| CALU | calumenin | -0.0282889 |
| TFRC | transferrin receptor | -0.0282421 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0281455 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279744 |
| CDK13 | cyclin-dependent kinase 13 | -0.027945 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0275138 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0273778 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0268056 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0267564 |
| HDLBP | high density lipoprotein binding protein | -0.0267364 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0267105 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0266634 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0266035 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0265917 |
| ACTN4 | actinin, alpha 4 | -0.0264529 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0263965 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0262991 |
| LDHA | lactate dehydrogenase A | -0.0262922 |
| FMNL2 | formin-like 2 | -0.026221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0258558 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025849 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0258376 |
| EHBP1 | EH domain binding protein 1 | -0.0257373 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0257338 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0256526 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.025541 |
| MAP4 | microtubule-associated protein 4 | -0.025436 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0253901 |
| MORF4L2 | mortality factor 4 like 2 | -0.0252002 |
| ANXA2 | annexin A2 | -0.0251384 |
