| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Perindopril (erbumine) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Perindopril (erbumine)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.168166 |
| NDRG1 | N-myc downstream regulated 1 | 0.11442 |
| STC1 | stanniocalcin 1 | 0.100595 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0787666 |
| FAM13A | family with sequence similarity 13, member A | 0.0761808 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0706345 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0647879 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0644477 |
| LOX | lysyl oxidase | 0.062897 |
| ATP13A3 | ATPase type 13A3 | 0.0624508 |
| LDHA | lactate dehydrogenase A | 0.0618826 |
| ADM | adrenomedullin | 0.0595915 |
| SPAG9 | sperm associated antigen 9 | 0.0592595 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0569914 |
| GOLGA4 | golgin A4 | 0.0569688 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0557766 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0520456 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0507078 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0493735 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0492745 |
| NGLY1 | N-glycanase 1 | 0.0474387 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.044417 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0438616 |
| DST | dystonin | 0.0433164 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0429997 |
| RND3 | Rho family GTPase 3 | 0.0422519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0418102 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0409607 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.040595 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0381654 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0371749 |
| FMNL2 | formin-like 2 | 0.0359804 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0350262 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0343534 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0342884 |
| COPA | coatomer protein complex, subunit alpha | 0.0338687 |
| TNS1 | tensin 1 | 0.0336071 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0328268 |
| VEGFA | vascular endothelial growth factor A | 0.0328164 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0314797 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307459 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0305034 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0301303 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0297468 |
| MMP12 | matrix metallopeptidase 12 | 0.0295049 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0292889 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0289992 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0289574 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0280027 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0276847 |
| HDAC9 | histone deacetylase 9 | 0.0273086 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0272959 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0265788 |
| TMF1 | TATA element modulatory factor 1 | 0.0265762 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0264004 |
| RUNX1 | runt-related transcription factor 1 | 0.0256442 |
| STC2 | stanniocalcin 2 | 0.0256274 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0253757 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0250977 |
| FNIP1 | folliculin interacting protein 1 | 0.0245651 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0239257 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0238629 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235751 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0235078 |
| CALR | calreticulin | 0.0232616 |
| LMNA | lamin A/C | 0.0229977 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0229561 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0226821 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0222814 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0219101 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.021672 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0216373 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214595 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0211711 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0211083 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.020943 |
| SETD5 | SET domain containing 5 | 0.0209259 |
| RAI1 | retinoic acid induced 1 | 0.0207016 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0206901 |
| RNF145 | ring finger protein 145 | 0.0204606 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0204451 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0202211 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0197825 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0195989 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0195644 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.019425 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0192956 |
| CD47 | CD47 molecule | 0.0191934 |
| RNF169 | ring finger protein 169 | 0.018858 |
| VEGFC | vascular endothelial growth factor C | 0.0187818 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0187645 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0186219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0186096 |
| HYOU1 | hypoxia up-regulated 1 | 0.0184235 |
| PCBP2 | poly(rC) binding protein 2 | 0.0183338 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0183224 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0183002 |
| PGM3 | phosphoglucomutase 3 | 0.018298 |
| NKTR | natural killer cell triggering receptor | 0.018226 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0181036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | -0.238266 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.170773 |
| COL1A1 | collagen, type I, alpha 1 | -0.140729 |
| TMSB10 | thymosin beta 10 | -0.114871 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0978292 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0916069 |
| COL1A2 | collagen, type I, alpha 2 | -0.0878804 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0876987 |
| ACTG1 | actin gamma 1 | -0.0842333 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0816349 |
| EMP1 | epithelial membrane protein 1 | -0.0761583 |
| MT2A | metallothionein 2A | -0.0736304 |
| FN1 | fibronectin 1 | -0.0702796 |
| HLA-B | major histocompatibility complex, class I, B | -0.0674555 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0672367 |
| PTMA | prothymosin, alpha | -0.0643421 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0611516 |
| CD44 | CD44 molecule (Indian blood group) | -0.0595717 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0591735 |
| ASPH | aspartate beta-hydroxylase | -0.0580049 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0576411 |
| RPL35A | ribosomal protein L35a | -0.0567049 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0563311 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0549633 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0543121 |
| MYO10 | myosin X | -0.0541581 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0504781 |
| RPS24 | ribosomal protein S24 | -0.04932 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0482941 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0481004 |
| AHNAK | AHNAK nucleoprotein | -0.0463071 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0454719 |
| POTEF | POTE ankyrin domain family, member F | -0.0447685 |
| FRMD4A | FERM domain containing 4A | -0.0437987 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0436279 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0412379 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0401637 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0392278 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0389817 |
| GLIS3 | GLIS family zinc finger 3 | -0.0377703 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.036458 |
| RPLP1 | ribosomal protein, large, P1 | -0.0359381 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0355748 |
| CLMP | CXADR-like membrane protein | -0.0350995 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350921 |
| OXR1 | oxidation resistance 1 | -0.0339745 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0336929 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0331404 |
| RPL23 | ribosomal protein L23 | -0.0326783 |
| KIAA1549L | KIAA1549-like | -0.0322314 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0319781 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0315895 |
| RPS8 | ribosomal protein S8 | -0.0304965 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0295608 |
| TPM4 | tropomyosin 4 | -0.0294489 |
| NAV1 | neuron navigator 1 | -0.0293101 |
| CD63 | CD63 molecule | -0.0288088 |
| S100A6 | S100 calcium binding protein A6 | -0.0287261 |
| RPL31 | ribosomal protein L31 | -0.0279131 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278495 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0276529 |
| CALU | calumenin | -0.0273803 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0270276 |
| RPL34 | ribosomal protein L34 | -0.0269005 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264612 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0261 |
| VIM | vimentin | -0.0253633 |
| CALD1 | caldesmon 1 | -0.0253179 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0251046 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0250927 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0249336 |
| MMP1 | matrix metallopeptidase 1 | -0.0249037 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0248182 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0243003 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0241403 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0240816 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0240379 |
| CDH13 | cadherin 13 | -0.0238073 |
| NRP1 | neuropilin 1 | -0.0235975 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0235373 |
| SEPTIN7 | septin 7 | -0.0234668 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0233243 |
| SEPTIN11 | septin 11 | -0.0232473 |
| IPO7 | importin 7 | -0.0231946 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0229827 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0229365 |
| VCAN | versican | -0.0229359 |
| RPS6 | ribosomal protein S6 | -0.022314 |
| IER3 | immediate early response 3 | -0.0223084 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0222842 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0221188 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0220597 |
| CCDC102B | coiled-coil domain containing 102B | -0.0220297 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0219397 |
| CAVIN1 | caveolae associated protein 1 | -0.0218685 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0216593 |
| RPL9 | ribosomal protein L9 | -0.0215953 |
| VCL | vinculin | -0.0215088 |
| PRSS23 | protease, serine, 23 | -0.0212806 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0211252 |
