Periodontitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) (Experimental Factor Ontology, EFO_0000649)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010518
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Genes

12 genes/proteins associated with the disease Periodontitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GGT1 gamma-glutamyltransferase 1 2.88009
MMP9 matrix metallopeptidase 9 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
ICAM1 intercellular adhesion molecule 1 1.41559
NOS2 nitric oxide synthase 2, inducible 1.10907
MMP8 matrix metallopeptidase 8 1.10104
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.06152
IL1B interleukin 1, beta 1.05274
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.03715
TNF tumor necrosis factor 1.02114
CXCL8 chemokine (C-X-C motif) ligand 8 1.01663
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.01062