Periodontitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) (Experimental Factor Ontology, EFO_0000649)
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Genes

1204 genes co-occuring with the disease Periodontitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
IL1B interleukin 1, beta 3.604
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 3.604
IL6 interleukin 6 3.489
MMP8 matrix metallopeptidase 8 3.459
TNF tumor necrosis factor 3.422
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 3.234
CXCL8 chemokine (C-X-C motif) ligand 8 3.215
IL1A interleukin 1, alpha 3.129
IL10 interleukin 10 3.101
ACP5 acid phosphatase 5, tartrate resistant 3.099
TLR2 toll-like receptor 2 3.06
IL17A interleukin 17A 3.059
RUNX2 runt-related transcription factor 2 3.034
TLR4 toll-like receptor 4 3.03
BGLAP bone gamma-carboxyglutamate (gla) protein 3.018
CRP C-reactive protein, pentraxin-related 2.986
MMP9 matrix metallopeptidase 9 2.918
IFNG interferon, gamma 2.88
JPH2 junctophilin 2 2.876
TRIM25 tripartite motif containing 25 2.843
BMP2 bone morphogenetic protein 2 2.836
CTSK cathepsin K 2.823
IL4 interleukin 4 2.792
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.766
TGFB1 transforming growth factor, beta 1 2.757
MMP1 matrix metallopeptidase 1 2.745
CD4 CD4 molecule 2.691
CCL2 chemokine (C-C motif) ligand 2 2.66
GLT6D1 glycosyltransferase 6 domain containing 1 2.654
LTF lactotransferrin 2.632
CTSC cathepsin C 2.627
SPP1 secreted phosphoprotein 1 2.626
SP7 Sp7 transcription factor 2.591
IL18 interleukin 18 2.59
MMP3 matrix metallopeptidase 3 2.582
CAMP cathelicidin antimicrobial peptide 2.581
TIMP1 TIMP metallopeptidase inhibitor 1 2.578
IBSP integrin-binding sialoprotein 2.567
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.553
MMP2 matrix metallopeptidase 2 2.52
MMP13 matrix metallopeptidase 13 2.516
ALB albumin 2.501
NLRP3 NLR family, pyrin domain containing 3 2.488
INS insulin 2.485
CEMP1 cementum protein 1 2.473
ELANE elastase, neutrophil expressed 2.47
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.467
DEFB103A defensin, beta 103A 2.467
DEFB4A defensin, beta 4A 2.457
ICAM1 intercellular adhesion molecule 1 2.442
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.441
FN1 fibronectin 1 2.439
MYD88 myeloid differentiation primary response 88 2.433
MPO myeloperoxidase 2.427
SOST sclerostin 2.422
DCSTAMP dendrocyte expressed seven transmembrane protein 2.421
IL2 interleukin 2 2.414
HTN3 histatin 3 2.41
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.41
CD8A CD8a molecule 2.373
DEFB1 defensin, beta 1 2.373
AMBN ameloblastin (enamel matrix protein) 2.364
CCL3 chemokine (C-C motif) ligand 3 2.363
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.361
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.361
DSPP dentin sialophosphoprotein 2.36
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.357
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.356
STATH statherin 2.335
FOS FBJ murine osteosarcoma viral oncogene homolog 2.328
DMP1 dentin matrix acidic phosphoprotein 1 2.321
IL13 interleukin 13 2.316
FGF2 fibroblast growth factor 2 (basic) 2.308
PRTN3 proteinase 3 2.298
THY1 Thy-1 cell surface antigen 2.298
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.295
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.293
CCL5 chemokine (C-C motif) ligand 5 2.285
C5AR1 complement component 5a receptor 1 2.284
ENG endoglin 2.279
CSF1 colony stimulating factor 1 (macrophage) 2.279
IL1RN interleukin 1 receptor antagonist 2.273
FOXP3 forkhead box P3 2.27
PXDN peroxidasin 2.27
PXDNL peroxidasin-like 2.27
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.265
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.264
CTSG cathepsin G 2.258
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.238
ACTB actin, beta 2.233
VCAM1 vascular cell adhesion molecule 1 2.223
PTPRC protein tyrosine phosphatase, receptor type, C 2.223
NT5E 5'-nucleotidase, ecto (CD73) 2.22
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.22
JUN jun proto-oncogene 2.219
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.213
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.212
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.209
CXCL10 chemokine (C-X-C motif) ligand 10 2.201
HTN1 histatin 1 2.19
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.189
PADI4 peptidyl arginine deiminase, type IV 2.171
IL22 interleukin 22 2.17
CCK cholecystokinin 2.164
TLR9 toll-like receptor 9 2.163
ALPL alkaline phosphatase, liver/bone/kidney 2.161
NOD2 nucleotide-binding oligomerization domain containing 2 2.153
PTH parathyroid hormone 2.153
IL33 interleukin 33 2.152
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.152
FGF7 fibroblast growth factor 7 2.152
SELE selectin E 2.151
CCL20 chemokine (C-C motif) ligand 20 2.146
LEP leptin 2.143
IL5 interleukin 5 2.137
ADIPOQ adiponectin, C1Q and collagen domain containing 2.135
IL17F interleukin 17F 2.131
NOD1 nucleotide-binding oligomerization domain containing 1 2.127
HMOX1 heme oxygenase 1 2.126
APOE apolipoprotein E 2.12
RETN resistin 2.111
CXCL12 chemokine (C-X-C motif) ligand 12 2.111
CSF3 colony stimulating factor 3 (granulocyte) 2.099
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.089
BMP7 bone morphogenetic protein 7 2.088
IL11 interleukin 11 2.083
MCAM melanoma cell adhesion molecule 2.077
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.077
RETNLB resistin like beta 2.072
TIMP2 TIMP metallopeptidase inhibitor 2 2.07
MRC1 mannose receptor, C type 1 2.07
SIGLEC5 sialic acid binding Ig-like lectin 5 2.063
C3 complement component 3 2.062
TLR1 toll-like receptor 1 2.061
CD68 CD68 molecule 2.06
PLG plasminogen 2.06
POSTN periostin, osteoblast specific factor 2.055
CTSS cathepsin S 2.053
CD86 CD86 molecule 2.048
LPO lactoperoxidase 2.048
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.047
GSDMD gasdermin D 2.046
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.045
ENO1 enolase 1, (alpha) 2.043
MAPK3 mitogen-activated protein kinase 3 2.043
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.038
TREM1 triggering receptor expressed on myeloid cells 1 2.037
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 2.034
FGF5 fibroblast growth factor 5 2.034
FGF16 fibroblast growth factor 16 2.033
FGF18 fibroblast growth factor 18 2.032
FGF20 fibroblast growth factor 20 2.032
FGF22 fibroblast growth factor 22 2.031
PADI2 peptidyl arginine deiminase, type II 2.03
FGF6 fibroblast growth factor 6 2.03
FGF10 fibroblast growth factor 10 2.027
FGF17 fibroblast growth factor 17 2.027
CD34 CD34 molecule 2.027
FGF4 fibroblast growth factor 4 2.027
FGF3 fibroblast growth factor 3 2.026
EGF epidermal growth factor 2.026
FGF9 fibroblast growth factor 9 2.025
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.025
CD44 CD44 molecule (Indian blood group) 2.024
OCSTAMP osteoclast stimulatory transmembrane protein 2.023
OSCAR osteoclast associated, immunoglobulin-like receptor 2.021
FGF8 fibroblast growth factor 8 (androgen-induced) 2.021
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.018
NAMPT nicotinamide phosphoribosyltransferase 2.013
COL1A1 collagen, type I, alpha 1 2.012
PECAM1 platelet/endothelial cell adhesion molecule 1 2.008
CTSB cathepsin B 2.001
CMC2 C-x(9)-C motif containing 2 1.998
AMY1B amylase, alpha 1B (salivary) 1.998
TLR5 toll-like receptor 5 1.997
AIM2 absent in melanoma 2 1.996
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.992
PPARG peroxisome proliferator-activated receptor gamma 1.985
CMKLR1 chemerin chemokine-like receptor 1 1.985
LAMC3 laminin, gamma 3 1.983
CST4 cystatin S 1.977
IRAK1 interleukin-1 receptor-associated kinase 1 1.976
IGF1 insulin-like growth factor 1 (somatomedin C) 1.969
ERV3-1 endogenous retrovirus group 3, member 1 1.967
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.967
SIRT1 sirtuin 1 1.966
A2M alpha-2-macroglobulin 1.963
ODAM odontogenic, ameloblast asssociated 1.956
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.943
CXCR4 chemokine (C-X-C motif) receptor 4 1.941
MMP12 matrix metallopeptidase 12 1.94
GSK3B glycogen synthase kinase 3 beta 1.937
ERVW-1 endogenous retrovirus group W, member 1 1.937
CCL4 chemokine (C-C motif) ligand 4 1.936
ALPG alkaline phosphatase, germ cell 1.936
MMP7 matrix metallopeptidase 7 1.935
ALPI alkaline phosphatase, intestinal 1.93
TLR3 toll-like receptor 3 1.928
BCL2 B-cell CLL/lymphoma 2 1.926
ELN elastin 1.926
DEFA1B defensin, alpha 1B 1.923
FPR1 formyl peptide receptor 1 1.922
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.919
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.918
GPX3 glutathione peroxidase 3 1.918
THNSL2 threonine synthase-like 2 (S. cerevisiae) 1.91
GPX5 glutathione peroxidase 5 1.91
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.909
NFE2L2 nuclear factor, erythroid 2-like 2 1.909
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.907
IL17RA interleukin 17 receptor A 1.906
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.906
GPX7 glutathione peroxidase 7 1.906
GPX6 glutathione peroxidase 6 1.906
GPX8 glutathione peroxidase 8 (putative) 1.906
GPX2 glutathione peroxidase 2 1.905
CD19 CD19 molecule 1.9
LY96 lymphocyte antigen 96 1.899
HMGB1 high mobility group box 1 1.899
STAT1 signal transducer and activator of transcription 1, 91kDa 1.899
TAC1 tachykinin, precursor 1 1.897
WNT5A wingless-type MMTV integration site family, member 5A 1.896
TP53 tumor protein p53 1.884
IL1R1 interleukin 1 receptor, type I 1.884
IL7 interleukin 7 1.882
LTA lymphotoxin alpha 1.882
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.881
OCLN occludin 1.881
SLPI secretory leukocyte peptidase inhibitor 1.88
ALPP alkaline phosphatase, placental 1.878
CD80 CD80 molecule 1.878
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 1.876
AGER advanced glycosylation end product-specific receptor 1.875
APP amyloid beta (A4) precursor protein 1.872
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.868
CXCR2 chemokine (C-X-C motif) receptor 2 1.865
IFNB1 interferon, beta 1, fibroblast 1.857
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.848
EDIL3 EGF-like repeats and discoidin I-like domains 3 1.844
CALCR calcitonin receptor 1.842
PTX3 pentraxin 3, long 1.839
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.838
CXCL2 chemokine (C-X-C motif) ligand 2 1.837
CD40 CD40 molecule, TNF receptor superfamily member 5 1.837
CD40LG CD40 ligand 1.836
IFNA1 interferon, alpha 1 1.834
FPR2 formyl peptide receptor 2 1.83
CD209 CD209 molecule 1.826
AZU1 azurocidin 1 1.822
ACE2 angiotensin I converting enzyme 2 1.822
HP haptoglobin 1.816
GPR32 G protein-coupled receptor 32 1.816
DEFB4B defensin, beta 4B 1.811
MMP20 matrix metallopeptidase 20 1.804
S100A8 S100 calcium binding protein A8 1.804
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.801
CD63 CD63 molecule 1.797
BMP4 bone morphogenetic protein 4 1.795
ACE angiotensin I converting enzyme 1.792
CSF1R colony stimulating factor 1 receptor 1.791
IDO1 indoleamine 2,3-dioxygenase 1 1.789
MUC7 mucin 7, secreted 1.786
AGBL2 ATP/GTP binding protein-like 2 1.782
CA6 carbonic anhydrase VI 1.781
TLR7 toll-like receptor 7 1.781
AMTN amelotin 1.78
BPIFA2 BPI fold containing family A, member 2 1.779
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.778
TJP1 tight junction protein 1 1.778
ARG1 arginase 1 1.777
CA9 carbonic anhydrase IX 1.777
AMY2B amylase, alpha 2B (pancreatic) 1.777
TBX21 T-box 21 1.776
KLK11 kallikrein-related peptidase 11 1.775
IL9 interleukin 9 1.775
LGALS3 lectin, galactoside-binding, soluble, 3 1.774
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.77
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.77
KNG1 kininogen 1 1.769
AMY2A amylase, alpha 2A (pancreatic) 1.769
SOCS3 suppressor of cytokine signaling 3 1.769
CD1C CD1c molecule 1.768
CCR2 chemokine (C-C motif) receptor 2 1.768
NOS2 nitric oxide synthase 2, inducible 1.767
IL37 interleukin 37 1.767
PHEX phosphate regulating endopeptidase homolog, X-linked 1.762
ENAM enamelin 1.762
GDF5 growth differentiation factor 5 1.762
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.76
FOXO1 forkhead box O1 1.758
CXCL5 chemokine (C-X-C motif) ligand 5 1.758
CD163 CD163 molecule 1.758
TLR6 toll-like receptor 6 1.757
CD1B CD1b molecule 1.755
MMP25 matrix metallopeptidase 25 1.753
VTN vitronectin 1.749
LTB4R leukotriene B4 receptor 1.744
CCL11 chemokine (C-C motif) ligand 11 1.741
CD9 CD9 molecule 1.74
AHR aryl hydrocarbon receptor 1.737
C1S complement component 1, s subcomponent 1.737
BAX BCL2-associated X protein 1.737
BSG basigin (Ok blood group) 1.736
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.736
IL34 interleukin 34 1.734
NLRP6 NLR family, pyrin domain containing 6 1.726
WNT3A wingless-type MMTV integration site family, member 3A 1.724
NOS3 nitric oxide synthase 3 (endothelial cell) 1.723
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.723
CD1D CD1d molecule 1.721
ANXA5 annexin A5 1.719
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 1.718
ABHD12B abhydrolase domain containing 12B 1.717
FGF13 fibroblast growth factor 13 1.714
LBP lipopolysaccharide binding protein 1.714
DPP7 dipeptidyl-peptidase 7 1.712
IL15 interleukin 15 1.711
CD1A CD1a molecule 1.71
VAMP3 vesicle-associated membrane protein 3 1.709
LCN2 lipocalin 2 1.708
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.707
CD274 CD274 molecule 1.704
LYZL1 lysozyme-like 1 1.703
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.703
MAPK8 mitogen-activated protein kinase 8 1.701
FGF23 fibroblast growth factor 23 1.701
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.7
SCARB1 scavenger receptor class B, member 1 1.698
SMR3B submaxillary gland androgen regulated protein 3B 1.697
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.697
CD83 CD83 molecule 1.695
S100A12 S100 calcium binding protein A12 1.687
TLR8 toll-like receptor 8 1.687
CD36 CD36 molecule (thrombospondin receptor) 1.686
OSM oncostatin M 1.684
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.684
GUSB glucuronidase, beta 1.684
C1R complement component 1, r subcomponent 1.682
CTRL chymotrypsin-like 1.681
LRP5 low density lipoprotein receptor-related protein 5 1.678
ANXA1 annexin A1 1.678
SOCS1 suppressor of cytokine signaling 1 1.676
SCARB2 scavenger receptor class B, member 2 1.674
CCRL2 chemokine (C-C motif) receptor-like 2 1.674
DPP4 dipeptidyl-peptidase 4 1.67
TREM2 triggering receptor expressed on myeloid cells 2 1.669
ALOX5 arachidonate 5-lipoxygenase 1.664
BECN1 beclin 1, autophagy related 1.651
CCR6 chemokine (C-C motif) receptor 6 1.65
SELL selectin L 1.649
CXCL9 chemokine (C-X-C motif) ligand 9 1.647
CREB1 cAMP responsive element binding protein 1 1.646
CD1E CD1e molecule 1.646
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 1.644
MMP10 matrix metallopeptidase 10 1.641
NLRC4 NLR family, CARD domain containing 4 1.64
FASLG Fas ligand (TNF superfamily, member 6) 1.636
IL3 interleukin 3 1.635
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.634
LOX lysyl oxidase 1.632
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.632
CD81 CD81 molecule 1.629
S100A9 S100 calcium binding protein A9 1.627
DEFA3 defensin, alpha 3, neutrophil-specific 1.622
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.622
MBL2 mannose-binding lectin (protein C) 2, soluble 1.622
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.621
HPX hemopexin 1.62
CCR7 chemokine (C-C motif) receptor 7 1.62
CST3 cystatin C 1.619
GDF2 growth differentiation factor 2 1.618
CST2 cystatin SA 1.616
SMAD2 SMAD family member 2 1.616
RHOA ras homolog family member A 1.616
NGF nerve growth factor (beta polypeptide) 1.613
VWF von Willebrand factor 1.61
CHUK conserved helix-loop-helix ubiquitous kinase 1.61
CYBB cytochrome b-245, beta polypeptide 1.608
CXCL6 chemokine (C-X-C motif) ligand 6 1.608
BMP6 bone morphogenetic protein 6 1.606
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.606
CYCS cytochrome c, somatic 1.606
CD28 CD28 molecule 1.605
GATA3 GATA binding protein 3 1.602
RRAGB Ras-related GTP binding B 1.599
C3AR1 complement component 3a receptor 1 1.597
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.594
CCL22 chemokine (C-C motif) ligand 22 1.592
HAMP hepcidin antimicrobial peptide 1.59
DEFB104A defensin, beta 104A 1.588
PTGES prostaglandin E synthase 1.585
CDH5 cadherin 5, type 2 (vascular endothelium) 1.585
CXCR3 chemokine (C-X-C motif) receptor 3 1.58
BDNF brain-derived neurotrophic factor 1.58
ASPN asporin 1.579
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.579
PGLYRP1 peptidoglycan recognition protein 1 1.579
CCR1 chemokine (C-C motif) receptor 1 1.578
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.576
PLAU plasminogen activator, urokinase 1.572
FDCSP follicular dendritic cell secreted protein 1.572
ESR1 estrogen receptor 1 1.572
RIPK2 receptor-interacting serine-threonine kinase 2 1.571
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.569
HBD hemoglobin, delta 1.568
HNMT histamine N-methyltransferase 1.567
ALCAM activated leukocyte cell adhesion molecule 1.567
SMAD3 SMAD family member 3 1.566
CDKN2A cyclin-dependent kinase inhibitor 2A 1.566
HSH2D hematopoietic SH2 domain containing 1.566
CST1 cystatin SN 1.565
SDC1 syndecan 1 1.565
IL25 interleukin 25 1.563
IL17C interleukin 17C 1.562
CTRB2 chymotrypsinogen B2 1.559
KEAP1 kelch-like ECH-associated protein 1 1.559
EDN1 endothelin 1 1.558
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.557
CTRB1 chymotrypsinogen B1 1.557
CLEC7A C-type lectin domain family 7, member A 1.557
TGFB3 transforming growth factor, beta 3 1.556
TXN thioredoxin 1.555
WNT10B wingless-type MMTV integration site family, member 10B 1.553
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 1.553
DLX5 distal-less homeobox 5 1.552
HSPA4 heat shock 70kDa protein 4 1.551
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.55
CD59 CD59 molecule, complement regulatory protein 1.549
DEFA1 defensin, alpha 1 1.548
NLRP1 NLR family, pyrin domain containing 1 1.548
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.546
IL6R interleukin 6 receptor 1.544
DMBT1 deleted in malignant brain tumors 1 1.543
IRF3 interferon regulatory factor 3 1.542
CA2 carbonic anhydrase II 1.541
NANOG Nanog homeobox 1.539
INSR insulin receptor 1.537
MMP28 matrix metallopeptidase 28 1.537
ZNF718 zinc finger protein 718 1.537
H3-3B H3.3 histone B 1.535
JAK2 Janus kinase 2 1.531
HDAC9 histone deacetylase 9 1.531
ACAN aggrecan 1.53
GPR141 G protein-coupled receptor 141 1.529
PCNA proliferating cell nuclear antigen 1.528
FERMT1 fermitin family member 1 1.528
H3C12 H3 clustered histone 12 1.528
LYZ lysozyme 1.523
JAK1 Janus kinase 1 1.523
EPO erythropoietin 1.523
H3-5 H3.5 histone 1.523
H3-4 H3.4 histone, cluster member 1.522
H3C13 H3 clustered histone 13 1.522
CCN2 cellular communication network factor 2 1.521
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 1.52
NLRP2 NLR family, pyrin domain containing 2 1.519
IL23A interleukin 23, alpha subunit p19 1.518
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.513
ADM adrenomedullin 1.512
CCND1 cyclin D1 1.512
IRF8 interferon regulatory factor 8 1.509
COL1A2 collagen, type I, alpha 2 1.508
FFAR2 free fatty acid receptor 2 1.506
GCG glucagon 1.506
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.505
CTSL cathepsin L 1.504
IDO2 indoleamine 2,3-dioxygenase 2 1.504
EFNB2 ephrin-B2 1.503
MLKL mixed lineage kinase domain-like 1.502
BPI bactericidal/permeability-increasing protein 1.501
CXCR1 chemokine (C-X-C motif) receptor 1 1.501
SMAD5 SMAD family member 5 1.501
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.499
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.495
DEFB104B defensin, beta 104B 1.495
MEPE matrix extracellular phosphoglycoprotein 1.494
C4A complement component 4A (Rodgers blood group) 1.494
DCN decorin 1.493
GC group-specific component (vitamin D binding protein) 1.493
CXCL13 chemokine (C-X-C motif) ligand 13 1.492
PYCARD PYD and CARD domain containing 1.491
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.491
UBE2K ubiquitin-conjugating enzyme E2K 1.491
PF4 platelet factor 4 1.49
GLB1 galactosidase, beta 1 1.49
NELFCD negative elongation factor complex member C/D 1.49
GPR18 G protein-coupled receptor 18 1.489
S100A7 S100 calcium binding protein A7 1.489
CXCL11 chemokine (C-X-C motif) ligand 11 1.489
SYK spleen tyrosine kinase 1.489
PI3 peptidase inhibitor 3, skin-derived 1.487
CLEC19A C-type lectin domain family 19, member A 1.484
CXCL3 chemokine (C-X-C motif) ligand 3 1.483
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.482
PTK2 protein tyrosine kinase 2 1.48
TGFA transforming growth factor, alpha 1.479
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.476
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.476
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.476
HSPB3 heat shock 27kDa protein 3 1.474
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.474
IL23R interleukin 23 receptor 1.472
EGFR epidermal growth factor receptor 1.472
AADACL2 arylacetamide deacetylase-like 2 1.471
PIGR polymeric immunoglobulin receptor 1.47
BGN biglycan 1.47
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 1.469
HAX1 HCLS1 associated protein X-1 1.469
CD207 CD207 molecule, langerin 1.469
CLU clusterin 1.469
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.468
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.463
MAPK14 mitogen-activated protein kinase 14 1.462
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.461
EPHB4 EPH receptor B4 1.46
TIMP3 TIMP metallopeptidase inhibitor 3 1.457
MTM1 myotubularin 1 1.456
CCL7 chemokine (C-C motif) ligand 7 1.456
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.456
SOX2 SRY (sex determining region Y)-box 2 1.456
CMA1 chymase 1, mast cell 1.455
MZB1 marginal zone B and B1 cell-specific protein 1.453
IRS1 insulin receptor substrate 1 1.452
KRT14 keratin 14, type I 1.45
IRAK4 interleukin-1 receptor-associated kinase 4 1.45
DNAH8 dynein, axonemal, heavy chain 8 1.447
CTSD cathepsin D 1.446
SOCS6 suppressor of cytokine signaling 6 1.446
DUOX2 dual oxidase 2 1.445
ICAM3 intercellular adhesion molecule 3 1.445
CLDN1 claudin 1 1.445
IL16 interleukin 16 1.445
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.443
SOX9 SRY (sex determining region Y)-box 9 1.443
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.442
KRT13 keratin 13, type I 1.442
CD69 CD69 molecule 1.441
TLR10 toll-like receptor 10 1.439
NOX4 NADPH oxidase 4 1.438
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.438
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.436
TSG101 tumor susceptibility 101 1.436
NKRF NFKB repressing factor 1.436
POU5F1 POU class 5 homeobox 1 1.435
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.433
NOG noggin 1.429
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.429
TBL1X transducin (beta)-like 1X-linked 1.429
ADAM17 ADAM metallopeptidase domain 17 1.425
SOD2 superoxide dismutase 2, mitochondrial 1.424
REN renin 1.424
IRF4 interferon regulatory factor 4 1.423
F3 coagulation factor III (thromboplastin, tissue factor) 1.423
CLDN7 claudin 7 1.421
NPY neuropeptide Y 1.419
PTEN phosphatase and tensin homolog 1.418
C5 complement component 5 1.418
DUOX1 dual oxidase 1 1.417
IFI16 interferon, gamma-inducible protein 16 1.417
IL19 interleukin 19 1.415
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.411
TIMP4 TIMP metallopeptidase inhibitor 4 1.41
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.41
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.409
SOD1 superoxide dismutase 1, soluble 1.408
IL32 interleukin 32 1.408
PLAT plasminogen activator, tissue 1.406
ATG5 autophagy related 5 1.405
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.404
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.402
PPARA peroxisome proliferator-activated receptor alpha 1.402
TECR trans-2,3-enoyl-CoA reductase 1.402
DUSP1 dual specificity phosphatase 1 1.402
PFN1 profilin 1 1.401
IL4R interleukin 4 receptor 1.4
IRAK3 interleukin-1 receptor-associated kinase 3 1.399
PTHLH parathyroid hormone-like hormone 1.398
CD38 CD38 molecule 1.398
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.397
NES nestin 1.395
FFAR4 free fatty acid receptor 4 1.395
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 1.393
IRF1 interferon regulatory factor 1 1.392
SAA1 serum amyloid A1 1.392
APOB apolipoprotein B 1.391
FERMT3 fermitin family member 3 1.389
PXN paxillin 1.388
BMP1 bone morphogenetic protein 1 1.387
FLG2 filaggrin family member 2 1.384
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.384
IFNL1 interferon, lambda 1 1.384
TYROBP TYRO protein tyrosine kinase binding protein 1.382
NEK7 NIMA-related kinase 7 1.38
ITLN1 intelectin 1 (galactofuranose binding) 1.379
RIPK3 receptor-interacting serine-threonine kinase 3 1.376
CAMTA1 calmodulin binding transcription activator 1 1.375
POMC proopiomelanocortin 1.375
AP3B2 adaptor-related protein complex 3, beta 2 subunit 1.374
KDM6B lysine (K)-specific demethylase 6B 1.372
TERT telomerase reverse transcriptase 1.372
TMPRSS2 transmembrane protease, serine 2 1.372
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.371
ALOX15 arachidonate 15-lipoxygenase 1.371
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.367
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.367
NCF1 neutrophil cytosolic factor 1 1.366
METTL3 methyltransferase like 3 1.366
NELL1 NEL-like 1 (chicken) 1.365
APOA1 apolipoprotein A-I 1.364
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.362
LPL lipoprotein lipase 1.361
CISH cytokine inducible SH2-containing protein 1.359
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.359
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.359
NEU1 sialidase 1 (lysosomal sialidase) 1.358
SAA2 serum amyloid A2 1.358
FBN1 fibrillin 1 1.356
CCL19 chemokine (C-C motif) ligand 19 1.355
MSX2 msh homeobox 2 1.355
NLRP12 NLR family, pyrin domain containing 12 1.354
XDH xanthine dehydrogenase 1.354
BPIFA1 BPI fold containing family A, member 1 1.353
FLG filaggrin 1.353
RORC RAR-related orphan receptor C 1.352
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.351
FURIN furin (paired basic amino acid cleaving enzyme) 1.351
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.35
CSTB cystatin B (stefin B) 1.349
PDZK1IP1 PDZK1 interacting protein 1 1.349
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1.349
FCAR Fc fragment of IgA receptor 1.348
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.347
IRF5 interferon regulatory factor 5 1.346
ITGAV integrin, alpha V 1.345
DCD dermcidin 1.345
JCHAIN joining chain of multimeric IgA and IgM 1.344
RRAGA Ras-related GTP binding A 1.344
KDR kinase insert domain receptor 1.344
STAT5B signal transducer and activator of transcription 5B 1.343
KLF4 Kruppel-like factor 4 (gut) 1.343
VIP vasoactive intestinal peptide 1.342
HDAC1 histone deacetylase 1 1.341
THBS1 thrombospondin 1 1.341
SPI1 Spi-1 proto-oncogene 1.34
RAG1 recombination activating gene 1 1.339
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.338
GHRL ghrelin/obestatin prepropeptide 1.337
GSR glutathione reductase 1.335
NQO1 NAD(P)H dehydrogenase, quinone 1 1.333
SOCS7 suppressor of cytokine signaling 7 1.332
STAT5A signal transducer and activator of transcription 5A 1.331
ARG2 arginase 2 1.33
IL17B interleukin 17B 1.33
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.33
C4B complement component 4B (Chido blood group) 1.328
NGFR nerve growth factor receptor 1.328
NOTCH1 notch 1 1.327
TMEM201 transmembrane protein 201 1.327
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.327
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.326
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.326
CD24 CD24 molecule 1.325
B2M beta-2-microglobulin 1.325
IL31 interleukin 31 1.324
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.323
BCL2L1 BCL2-like 1 1.322
IL7R interleukin 7 receptor 1.322
LDLR low density lipoprotein receptor 1.321
TGFB2 transforming growth factor, beta 2 1.321
COL3A1 collagen, type III, alpha 1 1.321
SFRP1 secreted frizzled-related protein 1 1.318
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.316
IL10RA interleukin 10 receptor, alpha 1.316
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.315
CD276 CD276 molecule 1.314
ADIPOR1 adiponectin receptor 1 1.313
VCL vinculin 1.313
RO60 Ro60, Y RNA binding protein 1.313
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.311
CDC42 cell division cycle 42 1.311
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.307
HSPB1 heat shock 27kDa protein 1 1.306
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.305
MAPT microtubule-associated protein tau 1.304
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.304
CCL21 chemokine (C-C motif) ligand 21 1.304
CCL17 chemokine (C-C motif) ligand 17 1.301
DLX3 distal-less homeobox 3 1.299
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.299
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.298
IL36G interleukin 36, gamma 1.298
CCL25 chemokine (C-C motif) ligand 25 1.296
GJA1 gap junction protein, alpha 1, 43kDa 1.295
PRR4 proline rich 4 (lacrimal) 1.295
LEPR leptin receptor 1.294
CD27 CD27 molecule 1.292
IL17RC interleukin 17 receptor C 1.291
FABP4 fatty acid binding protein 4, adipocyte 1.29
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.29
KLK4 kallikrein-related peptidase 4 1.289
HSPE1 heat shock 10kDa protein 1 1.289
TUG1 taurine up-regulated 1 (non-protein coding) 1.288
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.288
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.287
FFAR3 free fatty acid receptor 3 1.287
COL5A1 collagen, type V, alpha 1 1.286
BACE1 beta-site APP-cleaving enzyme 1 1.285
ANGPT1 angiopoietin 1 1.285
ADI1 acireductone dioxygenase 1 1.284
MAPK11 mitogen-activated protein kinase 11 1.283
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.282
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.282
F11R F11 receptor 1.282
AIF1 allograft inflammatory factor 1 1.28
AQP5 aquaporin 5 1.279
CXCL16 chemokine (C-X-C motif) ligand 16 1.278
ESR2 estrogen receptor 2 (ER beta) 1.278
NCAM1 neural cell adhesion molecule 1 1.277
FBXO38 F-box protein 38 1.276
CD79A CD79a molecule, immunoglobulin-associated alpha 1.276
FAP fibroblast activation protein, alpha 1.276
ADAM10 ADAM metallopeptidase domain 10 1.275
DNTT DNA nucleotidylexotransferase 1.275
IGFBP5 insulin-like growth factor binding protein 5 1.275
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.275
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.274
CCR3 chemokine (C-C motif) receptor 3 1.274
GLI1 GLI family zinc finger 1 1.273
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.273
TYRP1 tyrosinase-related protein 1 1.27
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.27
NOS1 nitric oxide synthase 1 (neuronal) 1.269
FOXO3 forkhead box O3 1.269
IFNGR1 interferon gamma receptor 1 1.269
ICAM2 intercellular adhesion molecule 2 1.268
CD2 CD2 molecule 1.267
FADD Fas (TNFRSF6)-associated via death domain 1.266
CCL8 chemokine (C-C motif) ligand 8 1.266
IL6ST interleukin 6 signal transducer 1.265
GPX4 glutathione peroxidase 4 1.264
CLEC4E C-type lectin domain family 4, member E 1.263
SNAI1 snail family zinc finger 1 1.263
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.262
CD47 CD47 molecule 1.262
LAMP2 lysosomal-associated membrane protein 2 1.26
SIRT6 sirtuin 6 1.259
PCP4 Purkinje cell protein 4 1.258
CSTA cystatin A (stefin A) 1.257
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.257
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.256
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.255
PRDM1 PR domain containing 1, with ZNF domain 1.254
SMAD4 SMAD family member 4 1.254
LIF leukemia inhibitory factor 1.253
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.253
IRAK2 interleukin-1 receptor-associated kinase 2 1.253
CALML5 calmodulin-like 5 1.252
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.251
ADGRE1 adhesion G protein-coupled receptor E1 1.251
MYH14 myosin, heavy chain 14, non-muscle 1.251
GRN granulin 1.248
AREG amphiregulin 1.247
CCL13 chemokine (C-C motif) ligand 13 1.246
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.246
PRF1 perforin 1 (pore forming protein) 1.246
IL18R1 interleukin 18 receptor 1 1.246
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.244
KITLG KIT ligand 1.243
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.242
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.241
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.24
MAP1A microtubule-associated protein 1A 1.239
TGFBR1 transforming growth factor, beta receptor 1 1.239
NFE2 nuclear factor, erythroid 2 1.238
MORN2 MORN repeat containing 2 1.237
SHISA9 shisa family member 9 1.236
STAT4 signal transducer and activator of transcription 4 1.236
PIP prolactin-induced protein 1.235
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.233
DENND2B DENN domain containing 2B 1.233
TFRC transferrin receptor 1.232
PTGDR prostaglandin D2 receptor (DP) 1.231
AXIN2 axin 2 1.231
CAV1 caveolin 1, caveolae protein, 22kDa 1.23
CD177 CD177 molecule 1.23
CHIA chitinase, acidic 1.23
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.23
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 1.23
APOH apolipoprotein H (beta-2-glycoprotein I) 1.229
SIRT3 sirtuin 3 1.229
IL21 interleukin 21 1.228
IFNA2 interferon, alpha 2 1.228
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.228
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.228
XBP1 X-box binding protein 1 1.227
ZNF57 zinc finger protein 57 1.227
HLA-B major histocompatibility complex, class I, B 1.226
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.225
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.225
HTRA1 HtrA serine peptidase 1 1.225
LTA4H leukotriene A4 hydrolase 1.224
CALML3 calmodulin-like 3 1.224
PTK2B protein tyrosine kinase 2 beta 1.224
MEFV Mediterranean fever 1.223
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.222
ATG7 autophagy related 7 1.222
TBK1 TANK-binding kinase 1 1.221
EGR1 early growth response 1 1.22
MAPK12 mitogen-activated protein kinase 12 1.22
ITGAD integrin, alpha D 1.218
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.218
TXNIP thioredoxin interacting protein 1.218
IGF2 insulin-like growth factor 2 1.217
NOX1 NADPH oxidase 1 1.217
DEF6 differentially expressed in FDCP 6 homolog (mouse) 1.216
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.216
GFM1 G elongation factor, mitochondrial 1 1.215
MAPK13 mitogen-activated protein kinase 13 1.215
MMP26 matrix metallopeptidase 26 1.215
LYST lysosomal trafficking regulator 1.215
LEF1 lymphoid enhancer-binding factor 1 1.215
H2BC21 H2B clustered histone 21 1.215
R3HDM1 R3H domain containing 1 1.214
ULK1 unc-51 like autophagy activating kinase 1 1.213
TUFT1 tuftelin 1 1.212
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.21
PTAFR platelet-activating factor receptor 1.21
IL17D interleukin 17D 1.209
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.208
CALML4 calmodulin-like 4 1.207
CALML6 calmodulin-like 6 1.206
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.206
HSPB2 heat shock 27kDa protein 2 1.205
BMP3 bone morphogenetic protein 3 1.205
EP300 E1A binding protein p300 1.205
IRF7 interferon regulatory factor 7 1.204
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.203
NCF2 neutrophil cytosolic factor 2 1.203
CRACR2A calcium release activated channel regulator 2A 1.203
MAP2K1 mitogen-activated protein kinase kinase 1 1.202
B3GAT1 beta-1,3-glucuronyltransferase 1 1.2
FAM20C family with sequence similarity 20, member C 1.2
CD5 CD5 molecule 1.2
NRP1 neuropilin 1 1.199
SPHK1 sphingosine kinase 1 1.199
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 1.199
FDPS farnesyl diphosphate synthase 1.199
TLN1 talin 1 1.198
F2 coagulation factor II (thrombin) 1.196
THBD thrombomodulin 1.193
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.193
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.193
KRT2 keratin 2, type II 1.192
RAG2 recombination activating gene 2 1.192
ANPEP alanyl (membrane) aminopeptidase 1.191
JAG1 jagged 1 1.191
GAS6 growth arrest-specific 6 1.191
PON1 paraoxonase 1 1.189
ANXA8 annexin A8 1.188
TGM2 transglutaminase 2 1.186
AHSG alpha-2-HS-glycoprotein 1.186
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.186
PADI3 peptidyl arginine deiminase, type III 1.185
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 1.184
HBA2 hemoglobin, alpha 2 1.184
IL1F10 interleukin 1 family, member 10 (theta) 1.184
VAMP8 vesicle-associated membrane protein 8 1.182
KRT4 keratin 4, type II 1.181
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 1.181
VEGFC vascular endothelial growth factor C 1.181
BCL6 B-cell CLL/lymphoma 6 1.18
CHIT1 chitinase 1 (chitotriosidase) 1.179
HDAC2 histone deacetylase 2 1.179
KL klotho 1.178
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.177
CST5 cystatin D 1.176
C5AR2 complement component 5a receptor 2 1.175
ZFP36 ZFP36 ring finger protein 1.175
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.174
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 1.174
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.171
PTH1R parathyroid hormone 1 receptor 1.171
KAT2A K(lysine) acetyltransferase 2A 1.17
RORA RAR-related orphan receptor A 1.169
AMELX amelogenin, X-linked 1.169
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.169
FGD5 FYVE, RhoGEF and PH domain containing 5 1.169
CFL1 cofilin 1 (non-muscle) 1.167
GDF15 growth differentiation factor 15 1.167
CGAS cyclic GMP-AMP synthase 1.167
TRAF1 TNF receptor-associated factor 1 1.166
PFN3 profilin 3 1.165
DSC1 desmocollin 1 1.163
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.163
LRP6 low density lipoprotein receptor-related protein 6 1.162
MME membrane metallo-endopeptidase 1.161
CA1 carbonic anhydrase I 1.161
IFNA17 interferon, alpha 17 1.16
SFRP2 secreted frizzled-related protein 2 1.159
DSG1 desmoglein 1 1.159
LYN LYN proto-oncogene, Src family tyrosine kinase 1.158
FCN3 ficolin (collagen/fibrinogen domain containing) 3 1.158
HNF4A hepatocyte nuclear factor 4, alpha 1.157
LAP3 leucine aminopeptidase 3 1.157
PFN4 profilin family, member 4 1.156
ADIPOR2 adiponectin receptor 2 1.155
SH3BP2 SH3-domain binding protein 2 1.155
TRAF3 TNF receptor-associated factor 3 1.154
BIRC5 baculoviral IAP repeat containing 5 1.154
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.154
S100P S100 calcium binding protein P 1.154
TFF3 trefoil factor 3 (intestinal) 1.154
TET2 tet methylcytosine dioxygenase 2 1.152
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.152
ROR2 receptor tyrosine kinase-like orphan receptor 2 1.151
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.151
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.149
MAPK1 mitogen-activated protein kinase 1 1.149
PGF placental growth factor 1.149
ZEB1 zinc finger E-box binding homeobox 1 1.148
NCF4 neutrophil cytosolic factor 4, 40kDa 1.148
BTK Bruton agammaglobulinemia tyrosine kinase 1.148
CLDN4 claudin 4 1.148
HLA-A major histocompatibility complex, class I, A 1.147
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.147
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.147
KRT10 keratin 10, type I 1.146
IL36RN interleukin 36 receptor antagonist 1.146
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.145
CFP complement factor properdin 1.143
ITGB6 integrin, beta 6 1.143
SUCNR1 succinate receptor 1 1.143
KRT1 keratin 1, type II 1.143
PADI6 peptidyl arginine deiminase, type VI 1.142
NCR2 natural cytotoxicity triggering receptor 2 1.141
OGA O-GlcNAcase 1.141
GSDMA gasdermin A 1.14
TSLP thymic stromal lymphopoietin 1.14
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.138
MMP11 matrix metallopeptidase 11 1.138
PDCD1LG2 programmed cell death 1 ligand 2 1.137
FNDC5 fibronectin type III domain containing 5 1.137
NOTCH2 notch 2 1.136
PLS1 plastin 1 1.136
MERTK MER proto-oncogene, tyrosine kinase 1.136
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.135
IL26 interleukin 26 1.134
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.134
ERN1 endoplasmic reticulum to nucleus signaling 1 1.133
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.133
CTH cystathionine gamma-lyase 1.132
TMEM37 transmembrane protein 37 1.131
KRT19 keratin 19, type I 1.131
LGALS1 lectin, galactoside-binding, soluble, 1 1.131
NLRC5 NLR family, CARD domain containing 5 1.13
PDCD1 programmed cell death 1 1.13
MMUT methylmalonyl-CoA mutase 1.129
PDGFB platelet-derived growth factor beta polypeptide 1.128
MMP15 matrix metallopeptidase 15 (membrane-inserted) 1.128
ATF4 activating transcription factor 4 1.128
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 1.127
PRSS3 protease, serine, 3 1.127
ATG12 autophagy related 12 1.127
SEC11C SEC11 homolog C (S. cerevisiae) 1.125
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.125
SQSTM1 sequestosome 1 1.125
CBS cystathionine-beta-synthase 1.125
ADAM8 ADAM metallopeptidase domain 8 1.123
CA8 carbonic anhydrase VIII 1.123
NAIP NLR family, apoptosis inhibitory protein 1.123
C4BPA complement component 4 binding protein, alpha 1.122
PCSK9 proprotein convertase subtilisin/kexin type 9 1.121
ACKR2 atypical chemokine receptor 2 1.121
BIRC3 baculoviral IAP repeat containing 3 1.121
GFER growth factor, augmenter of liver regeneration 1.12
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.119
PANX1 pannexin 1 1.119
H2AC18 H2A clustered histone 18 1.119
IL2RA interleukin 2 receptor, alpha 1.118
FMOD fibromodulin 1.118
MT1E metallothionein 1E 1.117
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 1.117
CCR9 chemokine (C-C motif) receptor 9 1.117
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.115
FAM180A family with sequence similarity 180, member A 1.114
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.113
CCN1 cellular communication network factor 1 1.113
OPRPN opiorphin prepropeptide 1.112
TRIM21 tripartite motif containing 21 1.111
LAMP1 lysosomal-associated membrane protein 1 1.111
PLEK pleckstrin 1.111
GNS glucosamine (N-acetyl)-6-sulfatase 1.11
MX1 MX dynamin-like GTPase 1 1.109
CD14 CD14 molecule 1.108
VCAN versican 1.108
SELPLG selectin P ligand 1.107
FAM20A family with sequence similarity 20, member A 1.106
TICAM1 toll-like receptor adaptor molecule 1 1.106
CD33 CD33 molecule 1.106
DEFB128 defensin, beta 128 1.105
H2AC20 H2A clustered histone 20 1.105
LCN1 lipocalin 1 1.103
FAS Fas cell surface death receptor 1.103
TPI1 triosephosphate isomerase 1 1.102
IL33R interleukin 33 receptor 1.102
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.101
GSTM1 glutathione S-transferase mu 1 1.1
TM9SF2 transmembrane 9 superfamily member 2 1.098
CP ceruloplasmin (ferroxidase) 1.098
FLNA filamin A, alpha 1.097
FTO fat mass and obesity associated 1.097
IL12RB2 interleukin 12 receptor, beta 2 1.096
DEFB113 defensin, beta 113 1.093
AGBL3 ATP/GTP binding protein-like 3 1.093
RBP4 retinol binding protein 4, plasma 1.093
PLEKHO1 pleckstrin homology domain containing, family O member 1 1.093
TFF2 trefoil factor 2 1.093
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.093
WNT1 wingless-type MMTV integration site family, member 1 1.091
ZNF675 zinc finger protein 675 1.091
CARD9 caspase recruitment domain family, member 9 1.091
RGS1 regulator of G-protein signaling 1 1.09
MFSD1 major facilitator superfamily domain containing 1 1.09
KAT2B K(lysine) acetyltransferase 2B 1.089
CD180 CD180 molecule 1.089
EPHX2 epoxide hydrolase 2, cytoplasmic 1.088
CADM1 cell adhesion molecule 1 1.088
EPAS1 endothelial PAS domain protein 1 1.087
ELAVL1 ELAV like RNA binding protein 1 1.087
ECE1 endothelin converting enzyme 1 1.086
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.085
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.085
IL1RAP interleukin 1 receptor accessory protein 1.085
HLA-C major histocompatibility complex, class I, C 1.085
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.085
PLPPR4 phospholipid phosphatase related 4 1.084
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 1.081
CD46 CD46 molecule, complement regulatory protein 1.081
MSX1 msh homeobox 1 1.081
SATB2 SATB homeobox 2 1.081
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 1.08
PAEP progestagen-associated endometrial protein 1.08
PF4V1 platelet factor 4 variant 1 1.079
SIRPB1 signal-regulatory protein beta 1 1.079
MUC2 mucin 2, oligomeric mucus/gel-forming 1.079
ANGPTL4 angiopoietin-like 4 1.078
ANXA2 annexin A2 1.077
ZBP1 Z-DNA binding protein 1 1.076
CYBA cytochrome b-245, alpha polypeptide 1.076
FSTL1 follistatin-like 1 1.076
TET1 tet methylcytosine dioxygenase 1 1.076
HDC histidine decarboxylase 1.074
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.073
TRAF3IP2 TRAF3 interacting protein 2 1.072
VIM vimentin 1.072
KLF2 Kruppel-like factor 2 1.071
GDNF glial cell derived neurotrophic factor 1.071
S1PR2 sphingosine-1-phosphate receptor 2 1.071
PLTP phospholipid transfer protein 1.069
SIRPA signal-regulatory protein alpha 1.068
SMAD6 SMAD family member 6 1.068
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.068
CKB creatine kinase, brain 1.068
MYH9 myosin, heavy chain 9, non-muscle 1.068
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.067
ZG16B zymogen granule protein 16B 1.067
TMEM258 transmembrane protein 258 1.066
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.066
PKM pyruvate kinase, muscle 1.065
HBA1 hemoglobin, alpha 1 1.065
TYK2 tyrosine kinase 2 1.064
PIEZO1 piezo-type mechanosensitive ion channel component 1 1.064
ATF6 activating transcription factor 6 1.064
IL24 interleukin 24 1.063
ORM1 orosomucoid 1 1.062
HDAC3 histone deacetylase 3 1.062
DICER1 dicer 1, ribonuclease type III 1.062
FLT1 fms-related tyrosine kinase 1 1.058
DET1 de-etiolated homolog 1 (Arabidopsis) 1.058
PINK1 PTEN induced putative kinase 1 1.057
ZNF136 zinc finger protein 136 1.057
TLN2 talin 2 1.057
TAS2R38 taste receptor, type 2, member 38 1.057
ACHE acetylcholinesterase (Yt blood group) 1.057
PROM1 prominin 1 1.056
KRAS Kirsten rat sarcoma viral oncogene homolog 1.055
POTEF POTE ankyrin domain family, member F 1.055
FFAR1 free fatty acid receptor 1 1.055
MB myoglobin 1.054
GSDME gasdermin E 1.054
SSUH2 ssu-2 homolog (C. elegans) 1.053
MRGPRX2 MAS-related GPR, member X2 1.053
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.052
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.052
NLRP10 NLR family, pyrin domain containing 10 1.052
PPARD peroxisome proliferator-activated receptor delta 1.052
TWIST1 twist family bHLH transcription factor 1 1.051
REG3G regenerating islet-derived 3 gamma 1.051
IVL involucrin 1.05
SREBF1 sterol regulatory element binding transcription factor 1 1.05
GPNMB glycoprotein (transmembrane) nmb 1.049
NLRX1 NLR family member X1 1.049
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 1.049
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.048
F2R coagulation factor II (thrombin) receptor 1.047
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.047
IFNA14 interferon, alpha 14 1.047
TGM3 transglutaminase 3 1.046
LCE6A late cornified envelope 6A 1.044
IFNA13 interferon, alpha 13 1.044
BCL2A1 BCL2-related protein A1 1.043
WNT10A wingless-type MMTV integration site family, member 10A 1.043
SMAD7 SMAD family member 7 1.043
LIN28A lin-28 homolog A (C. elegans) 1.043
CKMT1B creatine kinase, mitochondrial 1B 1.042
NID1 nidogen 1 1.042
PTGES2 prostaglandin E synthase 2 1.042
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.042
TMEM181 transmembrane protein 181 1.042
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.042
IFNA6 interferon, alpha 6 1.04
CCL23 chemokine (C-C motif) ligand 23 1.039
MMP17 matrix metallopeptidase 17 (membrane-inserted) 1.039
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.039
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.038
AGO2 argonaute RISC catalytic component 2 1.038
CKM creatine kinase, muscle 1.038
CFH complement factor H 1.037
CLCN7 chloride channel, voltage-sensitive 7 1.037
CHGA chromogranin A 1.037
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.037
SPAG4 sperm associated antigen 4 1.037
VDAC1 voltage-dependent anion channel 1 1.036
IFNA16 interferon, alpha 16 1.036
IFNA7 interferon, alpha 7 1.035
SEC11A SEC11 homolog A (S. cerevisiae) 1.034
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 1.034
CALR calreticulin 1.031
RGS10 regulator of G-protein signaling 10 1.031
LMNB1 lamin B1 1.031
PSEN1 presenilin 1 1.031
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.031
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.031
IFIH1 interferon induced with helicase C domain 1 1.03
ARRB2 arrestin, beta 2 1.03
MKX mohawk homeobox 1.03
GFAP glial fibrillary acidic protein 1.03
APLN apelin 1.03
CXCR5 chemokine (C-X-C motif) receptor 5 1.029
BRD4 bromodomain containing 4 1.029
IFNA4 interferon, alpha 4 1.029
IFNA21 interferon, alpha 21 1.028
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.028
IFNA8 interferon, alpha 8 1.028
IFNA10 interferon, alpha 10 1.028
PLCB2 phospholipase C, beta 2 1.027
ARRB1 arrestin, beta 1 1.026
TMC6 transmembrane channel-like 6 1.026
IFNA5 interferon, alpha 5 1.026
PTN pleiotrophin 1.026
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.025
PAX9 paired box 9 1.025
S100A4 S100 calcium binding protein A4 1.024
RUNX1 runt-related transcription factor 1 1.024
CYTH1 cytohesin 1 1.023
VAV1 vav 1 guanine nucleotide exchange factor 1.023
RAB27A RAB27A, member RAS oncogene family 1.022
TFEB transcription factor EB 1.022
KAT6B K(lysine) acetyltransferase 6B 1.022
CA13 carbonic anhydrase XIII 1.02
OAZ1 ornithine decarboxylase antizyme 1 1.019
BPIFB2 BPI fold containing family B, member 2 1.019
COL2A1 collagen, type II, alpha 1 1.019
CA3 carbonic anhydrase III 1.019
GCLC glutamate-cysteine ligase, catalytic subunit 1.019
AGTR1 angiotensin II receptor, type 1 1.019
MREG melanoregulin 1.018
CNR2 cannabinoid receptor 2 (macrophage) 1.016
CA5B carbonic anhydrase VB, mitochondrial 1.016
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.015
IGFBP3 insulin-like growth factor binding protein 3 1.015
LY86 lymphocyte antigen 86 1.015
IL36A interleukin 36, alpha 1.015
TICAM2 toll-like receptor adaptor molecule 2 1.014
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.014
HLA-DOA major histocompatibility complex, class II, DO alpha 1.013
WNT16 wingless-type MMTV integration site family, member 16 1.011
CFB complement factor B 1.01
RBSN rabenosyn, RAB effector 1.01
SHH sonic hedgehog 1.009
BCHE butyrylcholinesterase 1.009
IL2RG interleukin 2 receptor, gamma 1.008
PLCG1 phospholipase C, gamma 1 1.008
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 1.007
OMD osteomodulin 1.007
IL10RB interleukin 10 receptor, beta 1.007
HSPA8 heat shock 70kDa protein 8 1.007
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.005
TH tyrosine hydroxylase 1.005
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.005
PADI1 peptidyl arginine deiminase, type I 1.004
NCR1 natural cytotoxicity triggering receptor 1 1.002
JSRP1 junctional sarcoplasmic reticulum protein 1 1.002
SOD3 superoxide dismutase 3, extracellular 1.0