Peritonitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output. (Human Disease Ontology, DOID_8283)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010538
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Genes

171 genes/proteins associated with the disease Peritonitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GSK3B glycogen synthase kinase 3 beta 2.88009
IFNG interferon, gamma 2.88009
C5 complement component 5 2.88009
IL1B interleukin 1, beta 1.89976
TNF tumor necrosis factor 1.82604
IL10 interleukin 10 1.75993
MPO myeloperoxidase 1.7554
BAX BCL2-associated X protein 1.6169
CCL2 chemokine (C-C motif) ligand 2 1.60781
IL6 interleukin 6 1.58701
ICAM1 intercellular adhesion molecule 1 1.57994
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.52489
BCL2 B-cell CLL/lymphoma 2 1.48196
CAT catalase 1.45777
TIMP1 TIMP metallopeptidase inhibitor 1 1.45247
NOS2 nitric oxide synthase 2, inducible 1.4479
MAPK8 mitogen-activated protein kinase 8 1.43673
CXCL8 chemokine (C-X-C motif) ligand 8 1.42589
VCAM1 vascular cell adhesion molecule 1 1.41856
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.4087
VEGFA vascular endothelial growth factor A 1.4076
JUN jun proto-oncogene 1.40705
EGR1 early growth response 1 1.3917
FAS Fas cell surface death receptor 1.39002
IL1A interleukin 1, alpha 1.38669
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.38298
NOS1 nitric oxide synthase 1 (neuronal) 1.3716
PGD phosphogluconate dehydrogenase 1.36791
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.35473
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.35415
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.35127
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.35069
NOS3 nitric oxide synthase 3 (endothelial cell) 1.3484
MAPK3 mitogen-activated protein kinase 3 1.34811
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.34723
IL4 interleukin 4 1.34664
MAPK1 mitogen-activated protein kinase 1 1.3385
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.32015
CCNG1 cyclin G1 1.31956
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.31267
COL3A1 collagen, type III, alpha 1 1.3036
NPY neuropeptide Y 1.30177
SOD2 superoxide dismutase 2, mitochondrial 1.29626
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.29348
PARP1 poly (ADP-ribose) polymerase 1 1.29133
PER2 period circadian clock 2 1.28579
GUSB glucuronidase, beta 1.28364
CTSB cathepsin B 1.28027
CCL3 chemokine (C-C motif) ligand 3 1.27966
TP53 tumor protein p53 1.27502
HMOX1 heme oxygenase 1 1.27409
CD44 CD44 molecule (Indian blood group) 1.26917
FN1 fibronectin 1 1.26329
MAPK14 mitogen-activated protein kinase 14 1.26205
SPON1 spondin 1, extracellular matrix protein 1.25713
HMGB2 high mobility group box 2 1.25494
DDIT3 DNA-damage-inducible transcript 3 1.25059
B2M beta-2-microglobulin 1.24623
FOS FBJ murine osteosarcoma viral oncogene homolog 1.24213
IGFBP3 insulin-like growth factor binding protein 3 1.2368
TGFB1 transforming growth factor, beta 1 1.23265
TAGLN transgelin 1.22916
CXCL2 chemokine (C-X-C motif) ligand 2 1.22339
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.21759
S100A9 S100 calcium binding protein A9 1.21304
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.20913
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.20558
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.20526
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.20295
TLR4 toll-like receptor 4 1.20163
CALR calreticulin 1.2013
STAT1 signal transducer and activator of transcription 1, 91kDa 1.199
CLU clusterin 1.19672
MCL1 myeloid cell leukemia 1 1.19047
CCNB1 cyclin B1 1.19014
THBS1 thrombospondin 1 1.18816
CYBB cytochrome b-245, beta polypeptide 1.18456
SOD1 superoxide dismutase 1, soluble 1.18391
GSTM1 glutathione S-transferase mu 1 1.1753
PER1 period circadian clock 1 1.17431
HSPA1A heat shock 70kDa protein 1A 1.17
CXCL10 chemokine (C-X-C motif) ligand 10 1.16401
LHB luteinizing hormone beta polypeptide 1.16401
GPX3 glutathione peroxidase 3 1.16203
PYCARD PYD and CARD domain containing 1.1607
TUBB tubulin, beta class I 1.1607
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.15899
BAK1 BCL2-antagonist/killer 1 1.15865
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.15357
IL2 interleukin 2 1.15156
PRL prolactin 1.14954
MMP13 matrix metallopeptidase 13 1.14885
F3 coagulation factor III (thromboplastin, tissue factor) 1.14713
LCN2 lipocalin 2 1.14098
MMP9 matrix metallopeptidase 9 1.13963
BTG2 BTG family, member 2 1.13929
ATF4 activating transcription factor 4 1.13758
THBD thrombomodulin 1.13724
IL12B interleukin 12B 1.13621
CD14 CD14 molecule 1.13143
MARCKS myristoylated alanine-rich protein kinase C substrate 1.12973
IGF1R insulin-like growth factor 1 receptor 1.12872
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.12737
MMP3 matrix metallopeptidase 3 1.12564
NPPC natriuretic peptide C 1.1253
CTSD cathepsin D 1.12391
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.12151
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.1198
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.11673
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.11396
CCL5 chemokine (C-C motif) ligand 5 1.1136
HSF1 heat shock transcription factor 1 1.11116
GHR growth hormone receptor 1.11116
OPRK1 opioid receptor, kappa 1 1.10907
CD4 CD4 molecule 1.10838
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.10838
GSTA4 glutathione S-transferase alpha 4 1.10665
SPP1 secreted phosphoprotein 1 1.09401
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.09366
ARG2 arginase 2 1.09366
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.08726
INHBA inhibin, beta A 1.08091
NGF nerve growth factor (beta polypeptide) 1.07947
AQP1 aquaporin 1 (Colton blood group) 1.07696
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.07518
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.07482
CTGF connective tissue growth factor 1.07411
DYNLL1 dynein, light chain, LC8-type 1 1.07057
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.06881
PLAT plasminogen activator, tissue 1.06808
BCL2L1 BCL2-like 1 1.06808
H2AFX H2A histone family, member X 1.06808
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.06479
CCL7 chemokine (C-C motif) ligand 7 1.06333
CCKBR cholecystokinin B receptor 1.06044
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.059
VIM vimentin 1.059
CALB1 calbindin 1, 28kDa 1.05349
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.04794
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.04647
ADIPOQ adiponectin, C1Q and collagen domain containing 1.04427
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.04389
PENK proenkephalin 1.04276
APP amyloid beta (A4) precursor protein 1.04276
PRKCB protein kinase C, beta 1.04239
PCNA proliferating cell nuclear antigen 1.04163
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.04088
ANXA2 annexin A2 1.03715
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.03715
BBC3 BCL2 binding component 3 1.03678
TH tyrosine hydroxylase 1.03382
FASN fatty acid synthase 1.03382
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.03345
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.03271
HSPB1 heat shock 27kDa protein 1 1.03122
SRR serine racemase 1.03084
EIF5A eukaryotic translation initiation factor 5A 1.02821
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.02634
PF4 platelet factor 4 1.02522
GH1 growth hormone 1 1.02447
RRM2 ribonucleotide reductase M2 1.02114
SRXN1 sulfiredoxin 1 1.01966
ALB albumin 1.0189
ANXA1 annexin A1 1.01814
EGR3 early growth response 3 1.01663
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.01212
EDNRB endothelin receptor type B 1.01137
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.01137
IL1RN interleukin 1 receptor antagonist 1.01137
GSTA2 glutathione S-transferase alpha 2 1.01137
SYP synaptophysin 1.01062