| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting PUM1 in K562 cell line (Study accession: SRP013565) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_10035_KD_PUM1_SRP013565 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MASP2 | mannan-binding lectin serine peptidase 2 | 6.32944 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 5.88612 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 5.4458 |
| C8ORF59 | chromosome 8 open reading frame 59 | 5.25443 |
| CLVS1 | clavesin 1 | 5.25443 |
| ASTN1 | astrotactin 1 | 4.91933 |
| GGCX | gamma-glutamyl carboxylase | 4.7013 |
| PARD6G | par-6 family cell polarity regulator gamma | 4.39273 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 | 4.38532 |
| USP34 | ubiquitin specific peptidase 34 | 4.30765 |
| CCNA2 | cyclin A2 | 4.1122 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 | 3.6857 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 3.41638 |
| CLCC1 | chloride channel CLIC-like 1 | 3.3484 |
| KIF2A | kinesin heavy chain member 2A | 3.31906 |
| THUMPD1 | THUMP domain containing 1 | 3.19883 |
| C5ORF45 | chromosome 5 open reading frame 45 | 3.18303 |
| EXOSC9 | exosome component 9 | 3.17623 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 3.16146 |
| NIT2 | nitrilase family, member 2 | 3.08767 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | 3.00358 |
| MTMR7 | myotubularin related protein 7 | 2.95141 |
| ZMYM1 | zinc finger, MYM-type 1 | 2.90855 |
| RAB31 | RAB31, member RAS oncogene family | 2.82408 |
| PMPCB | peptidase (mitochondrial processing) beta | 2.79157 |
| CDCP1 | CUB domain containing protein 1 | 2.76054 |
| ERCC1 | excision repair cross-complementation group 1 | 2.73016 |
| CAPN2 | calpain 2, (m/II) large subunit | 2.65119 |
| IMMP1L | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 2.62207 |
| PEX1 | peroxisomal biogenesis factor 1 | 2.60518 |
| EIF2B1 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 2.59419 |
| FAM168A | family with sequence similarity 168, member A | 2.57546 |
| BEST1 | bestrophin 1 | 2.53165 |
| CCNI2 | cyclin I family, member 2 | 2.53027 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A | 2.52653 |
| FMNL2 | formin-like 2 | 2.43391 |
| FRYL | FRY-like | 2.29333 |
| ACO2 | aconitase 2, mitochondrial | 2.26575 |
| POLH | polymerase (DNA directed), eta | 2.26185 |
| STK17A | serine/threonine kinase 17a | 2.25998 |
| EML5 | echinoderm microtubule associated protein like 5 | 2.24428 |
| FAM118B | family with sequence similarity 118, member B | 2.23639 |
| RBPMS | RNA binding protein with multiple splicing | 2.23317 |
| GYG1 | glycogenin 1 | 2.18461 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 2.18368 |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | 2.17915 |
| LAPTM5 | lysosomal protein transmembrane 5 | 2.17915 |
| IDI2 | isopentenyl-diphosphate delta isomerase 2 | 2.14131 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 2.12461 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 2.10139 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | 2.09079 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 2.05329 |
| TMEM50B | transmembrane protein 50B | 2.04894 |
| DDIT3 | DNA-damage-inducible transcript 3 | 2.01967 |
| PEX10 | peroxisomal biogenesis factor 10 | 2.00979 |
| ZNF263 | zinc finger protein 263 | 2.009 |
| PAQR3 | progestin and adipoQ receptor family member III | 1.98656 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 1.92292 |
| PKD2L2 | polycystic kidney disease 2-like 2 | 1.89631 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 1.87999 |
| LYSMD4 | LysM, putative peptidoglycan-binding, domain containing 4 | 1.84971 |
| CEP290 | centrosomal protein 290kDa | 1.84841 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 1.82298 |
| ATXN2 | ataxin 2 | 1.81876 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 1.81259 |
| PPAPDC1B | phosphatidic acid phosphatase type 2 domain containing 1B | 1.80809 |
| THUMPD3 | THUMP domain containing 3 | 1.79098 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 | 1.76451 |
| PRG4 | proteoglycan 4 | 1.7625 |
| BAG2 | BCL2-associated athanogene 2 | 1.73692 |
| FAM69B | family with sequence similarity 69, member B | 1.7304 |
| TYMS | thymidylate synthetase | 1.68977 |
| NRG4 | neuregulin 4 | 1.6782 |
| ABI1 | abl-interactor 1 | 1.6326 |
| TMEM263 | transmembrane protein 263 | 1.63071 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | 1.63071 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | 1.63004 |
| ZNF235 | zinc finger protein 235 | 1.62464 |
| C6ORF120 | chromosome 6 open reading frame 120 | 1.61937 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) | 1.61856 |
| RNF169 | ring finger protein 169 | 1.60859 |
| RNF39 | ring finger protein 39 | 1.59869 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 1.59844 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 1.59218 |
| PPID | peptidylprolyl isomerase D | 1.59218 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 1.59218 |
| CENPU | centromere protein U | 1.56244 |
| AKTIP | AKT interacting protein | 1.54536 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 1.54536 |
| HBP1 | HMG-box transcription factor 1 | 1.53488 |
| NEMF | nuclear export mediator factor | 1.52468 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 1.52213 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | 1.51996 |
| PP2D1 | protein phosphatase 2C-like domain containing 1 | 1.49817 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 1.49697 |
| LONP2 | lon peptidase 2, peroxisomal | 1.49697 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 1.49297 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide | 1.48376 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 1.48262 |
| RGS17 | regulator of G-protein signaling 17 | 1.47644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| C9ORF43 | chromosome 9 open reading frame 43 | -9.87791 |
| COQ5 | coenzyme Q5 homolog, methyltransferase (S. cerevisiae) | -9.65257 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -8.74718 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -8.63696 |
| HIST1H4I | histone cluster 1, H4i | -8.63696 |
| MVK | mevalonate kinase | -8.54076 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | -7.83551 |
| MROH5 | maestro heat-like repeat family member 5 | -7.39311 |
| PRR19 | proline rich 19 | -7.36587 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -7.27602 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -6.84996 |
| CASKIN1 | CASK interacting protein 1 | -6.75984 |
| OR51B6 | olfactory receptor, family 51, subfamily B, member 6 | -6.50859 |
| CCDC18 | coiled-coil domain containing 18 | -6.05264 |
| C1ORF226 | chromosome 1 open reading frame 226 | -6.03474 |
| CDC42SE1 | CDC42 small effector 1 | -6.00274 |
| RPS28 | ribosomal protein S28 | -5.61625 |
| TCP1 | t-complex 1 | -5.49045 |
| RAPSN | receptor-associated protein of the synapse | -5.08513 |
| UQCC3 | ubiquinol-cytochrome c reductase complex assembly factor 3 | -4.88282 |
| ATG9B | autophagy related 9B | -4.65766 |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) | -4.42299 |
| ABHD16B | abhydrolase domain containing 16B | -4.27435 |
| HIST1H1C | histone cluster 1, H1c | -4.22456 |
| HOOK2 | hook microtubule-tethering protein 2 | -4.19268 |
| RANBP1 | RAN binding protein 1 | -4.19268 |
| IFT80 | intraflagellar transport 80 | -4.06461 |
| SAMD11 | sterile alpha motif domain containing 11 | -3.78628 |
| SRPK3 | SRSF protein kinase 3 | -3.38846 |
| KCP | kielin/chordin-like protein | -3.33364 |
| DNASE1 | deoxyribonuclease I | -3.32248 |
| UFSP2 | UFM1-specific peptidase 2 | -3.27539 |
| ICAM3 | intercellular adhesion molecule 3 | -2.77523 |
| YBX1 | Y box binding protein 1 | -2.76054 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -2.74284 |
| FAM35A | family with sequence similarity 35, member A | -2.60306 |
| ENO3 | enolase 3 (beta, muscle) | -2.57653 |
| CENPN | centromere protein N | -2.53595 |
| BCAN | brevican | -2.53165 |
| KRT17 | keratin 17, type I | -2.46501 |
| MFSD12 | major facilitator superfamily domain containing 12 | -2.40781 |
| C19ORF54 | chromosome 19 open reading frame 54 | -2.38022 |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | -2.37413 |
| C10ORF2 | chromosome 10 open reading frame 2 | -2.32866 |
| LAMA5 | laminin, alpha 5 | -2.27486 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -2.23639 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -2.15756 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | -2.14131 |
| CENPO | centromere protein O | -2.0986 |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | -2.02346 |
| ABCC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | -2.02346 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.01817 |
| UBXN11 | UBX domain protein 11 | -2.00672 |
| MATN1 | matrilin 1, cartilage matrix protein | -1.95366 |
| METTL12 | methyltransferase like 12 | -1.952 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | -1.92041 |
| EML2 | echinoderm microtubule associated protein like 2 | -1.85591 |
| RBM7 | RNA binding motif protein 7 | -1.84644 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor | -1.82582 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -1.82271 |
| SSR4 | signal sequence receptor, delta | -1.8166 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | -1.81259 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | -1.80162 |
| MRPS12 | mitochondrial ribosomal protein S12 | -1.78307 |
| CCDC151 | coiled-coil domain containing 151 | -1.77692 |
| OR51M1 | olfactory receptor, family 51, subfamily M, member 1 | -1.76367 |
| FADS1 | fatty acid desaturase 1 | -1.76048 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -1.7355 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -1.70783 |
| KIF5A | kinesin family member 5A | -1.68917 |
| CDHR5 | cadherin-related family member 5 | -1.67447 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -1.66525 |
| FAM120AOS | family with sequence similarity 120A opposite strand | -1.66525 |
| F8 | coagulation factor VIII, procoagulant component | -1.66191 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | -1.65797 |
| CCDC42B | coiled-coil domain containing 42B | -1.60555 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) | -1.60212 |
| APC2 | adenomatosis polyposis coli 2 | -1.60046 |
| SAR1B | secretion associated, Ras related GTPase 1B | -1.59246 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -1.5873 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | -1.54536 |
| THAP6 | THAP domain containing 6 | -1.54129 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | -1.54129 |
| RBM27 | RNA binding motif protein 27 | -1.49608 |
| GPANK1 | G patch domain and ankyrin repeats 1 | -1.49456 |
| PEX14 | peroxisomal biogenesis factor 14 | -1.49297 |
| PIH1D1 | PIH1 domain containing 1 | -1.49297 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | -1.49297 |
| C10ORF95 | chromosome 10 open reading frame 95 | -1.49147 |
| MAP7D1 | MAP7 domain containing 1 | -1.48533 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -1.48262 |
| GPN3 | GPN-loop GTPase 3 | -1.46794 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -1.46401 |
| TXNRD2 | thioredoxin reductase 2 | -1.46033 |
| IK | IK cytokine, down-regulator of HLA II | -1.4581 |
| HMGA1 | high mobility group AT-hook 1 | -1.4581 |
| SWI5 | SWI5 recombination repair homolog (yeast) | -1.44063 |
| FAM134C | family with sequence similarity 134, member C | -1.43454 |
| RDH13 | retinol dehydrogenase 13 (all-trans/9-cis) | -1.43392 |
| PNCK | pregnancy up-regulated nonubiquitous CaM kinase | -1.43261 |
