| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting RPS19 in K562 cell line (Study accession: SRP013565) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_10052_KD_RPS19_SRP013565 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CPSF3L | cleavage and polyadenylation specific factor 3-like | 17.8697 |
| PLLP | plasmolipin | 16.8139 |
| NOXO1 | NADPH oxidase organizer 1 | 16.1638 |
| LAMA5 | laminin, alpha 5 | 14.9765 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | 11.6277 |
| GDF9 | growth differentiation factor 9 | 9.36541 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 9.09489 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 | 8.98703 |
| SAMD11 | sterile alpha motif domain containing 11 | 8.93336 |
| C9ORF43 | chromosome 9 open reading frame 43 | 8.54072 |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 | 8.54072 |
| TATDN1 | TatD DNase domain containing 1 | 8.53741 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 | 8.53636 |
| SEPP1 | selenoprotein P, plasma, 1 | 8.26513 |
| C1ORF122 | chromosome 1 open reading frame 122 | 8.22238 |
| DNAAF3 | dynein, axonemal, assembly factor 3 | 7.53315 |
| ZACN | zinc activated ligand-gated ion channel | 7.46111 |
| FAM175A | family with sequence similarity 175, member A | 7.08199 |
| PEX14 | peroxisomal biogenesis factor 14 | 6.77158 |
| GPR137 | G protein-coupled receptor 137 | 6.64652 |
| CENPN | centromere protein N | 6.61893 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 6.53695 |
| MROH1 | maestro heat-like repeat family member 1 | 6.51792 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | 6.51006 |
| TECPR1 | tectonin beta-propeller repeat containing 1 | 6.45956 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 6.22975 |
| CFL1 | cofilin 1 (non-muscle) | 6.15911 |
| PMPCB | peptidase (mitochondrial processing) beta | 6.02239 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 5.97927 |
| MARS | methionyl-tRNA synthetase | 5.97502 |
| B3GAT2 | beta-1,3-glucuronyltransferase 2 | 5.70209 |
| GPANK1 | G patch domain and ankyrin repeats 1 | 5.66392 |
| APC2 | adenomatosis polyposis coli 2 | 5.5749 |
| DAP3 | death associated protein 3 | 5.48432 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 5.43813 |
| STAB1 | stabilin 1 | 5.37238 |
| SNX22 | sorting nexin 22 | 5.34533 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 5.27838 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 5.23757 |
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 5.16247 |
| MUTYH | mutY homolog | 5.16229 |
| EPHA1 | EPH receptor A1 | 5.10133 |
| ZNF593OS | ZNF593 opposite strand | 5.09672 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 5.03966 |
| JMJD8 | jumonji domain containing 8 | 4.95798 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 4.91128 |
| ARL10 | ADP-ribosylation factor-like 10 | 4.83648 |
| PP2D1 | protein phosphatase 2C-like domain containing 1 | 4.71595 |
| ZNF232 | zinc finger protein 232 | 4.68919 |
| PRPF31 | pre-mRNA processing factor 31 | 4.68044 |
| CCDC18 | coiled-coil domain containing 18 | 4.62152 |
| PAQR3 | progestin and adipoQ receptor family member III | 4.62152 |
| NOL7 | nucleolar protein 7, 27kDa | 4.61485 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | 4.45397 |
| C21ORF2 | chromosome 21 open reading frame 2 | 4.26863 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 4.10572 |
| CCDC78 | coiled-coil domain containing 78 | 4.10316 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | 4.01961 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 | 4.01286 |
| SLC46A1 | solute carrier family 46 (folate transporter), member 1 | 4.00527 |
| TMEM97 | transmembrane protein 97 | 3.92706 |
| SPATA9 | spermatogenesis associated 9 | 3.89553 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | 3.89263 |
| FBXL6 | F-box and leucine-rich repeat protein 6 | 3.89052 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 3.88508 |
| CNTD1 | cyclin N-terminal domain containing 1 | 3.75768 |
| LRRC47 | leucine rich repeat containing 47 | 3.69209 |
| GPS1 | G protein pathway suppressor 1 | 3.62647 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 3.62647 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | 3.57555 |
| SS18L2 | synovial sarcoma translocation gene on chromosome 18-like 2 | 3.56694 |
| TSC2 | tuberous sclerosis 2 | 3.54992 |
| PTOV1 | prostate tumor overexpressed 1 | 3.53745 |
| OBSL1 | obscurin-like 1 | 3.45703 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 3.4499 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 3.43294 |
| BMP6 | bone morphogenetic protein 6 | 3.39318 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | 3.34324 |
| PITPNA | phosphatidylinositol transfer protein, alpha | 3.34042 |
| TMEM262 | transmembrane protein 262 | 3.3081 |
| C15ORF40 | chromosome 15 open reading frame 40 | 3.27017 |
| C5ORF45 | chromosome 5 open reading frame 45 | 3.26004 |
| ENDOG | endonuclease G | 3.25808 |
| PTCD1 | pentatricopeptide repeat domain 1 | 3.24314 |
| NPC1 | Niemann-Pick disease, type C1 | 3.22497 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 3.20058 |
| ZCWPW2 | zinc finger, CW type with PWWP domain 2 | 3.19931 |
| MYO15B | myosin XVB | 3.15787 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 3.11773 |
| TICRR | TOPBP1-interacting checkpoint and replication regulator | 3.06367 |
| CCDC151 | coiled-coil domain containing 151 | 3.00805 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) | 2.99182 |
| THAP6 | THAP domain containing 6 | 2.98255 |
| FAM161B | family with sequence similarity 161, member B | 2.98071 |
| LRRC24 | leucine rich repeat containing 24 | 2.96455 |
| ZSCAN22 | zinc finger and SCAN domain containing 22 | 2.95607 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 2.95607 |
| ZNF891 | zinc finger protein 891 | 2.95289 |
| PCBP2 | poly(rC) binding protein 2 | 2.94265 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.89319 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERI2 | ERI1 exoribonuclease family member 2 | -15.4203 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -12.771 |
| UBXN11 | UBX domain protein 11 | -11.1148 |
| NEB | nebulin | -9.65924 |
| SPC24 | SPC24, NDC80 kinetochore complex component | -9.21124 |
| FAM92A1 | family with sequence similarity 92, member A1 | -8.85379 |
| TRIM52 | tripartite motif containing 52 | -8.74329 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -8.69543 |
| SLC16A4 | solute carrier family 16, member 4 | -8.40224 |
| ZNF394 | zinc finger protein 394 | -7.87988 |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | -7.83818 |
| COX20 | COX20 cytochrome c oxidase assembly factor | -7.59207 |
| HMGA1 | high mobility group AT-hook 1 | -7.48672 |
| BRD7 | bromodomain containing 7 | -7.00017 |
| ANKRD61 | ankyrin repeat domain 61 | -6.98151 |
| RAPSN | receptor-associated protein of the synapse | -6.79686 |
| MRPS18C | mitochondrial ribosomal protein S18C | -6.79133 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | -6.68237 |
| ATXN3L | ataxin 3-like | -6.6113 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -6.57997 |
| RDH13 | retinol dehydrogenase 13 (all-trans/9-cis) | -6.51139 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | -6.41936 |
| SIGLEC10 | sialic acid binding Ig-like lectin 10 | -6.34976 |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) | -6.08874 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -5.83166 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -5.76642 |
| LAPTM5 | lysosomal protein transmembrane 5 | -5.67907 |
| CALR | calreticulin | -5.61948 |
| NAPSA | napsin A aspartic peptidase | -5.58345 |
| TRAPPC4 | trafficking protein particle complex 4 | -5.56717 |
| ZNF710 | zinc finger protein 710 | -5.03124 |
| C1ORF226 | chromosome 1 open reading frame 226 | -5.0311 |
| RGMA | repulsive guidance molecule family member a | -5.01357 |
| KRT18 | keratin 18, type I | -5.00836 |
| FKRP | fukutin related protein | -4.84676 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -4.80865 |
| SPAST | spastin | -4.77113 |
| ACTR3C | ARP3 actin-related protein 3 homolog C (yeast) | -4.71863 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -4.71625 |
| CDCP1 | CUB domain containing protein 1 | -4.70815 |
| RPL13A | ribosomal protein L13a | -4.67553 |
| ATG10 | autophagy related 10 | -4.62307 |
| OR51B6 | olfactory receptor, family 51, subfamily B, member 6 | -4.62152 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | -4.61485 |
| C19ORF54 | chromosome 19 open reading frame 54 | -4.59287 |
| LRRC41 | leucine rich repeat containing 41 | -4.52254 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | -4.46282 |
| CTSB | cathepsin B | -4.26863 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) | -4.24871 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | -4.21984 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 | -4.21469 |
| FAM184B | family with sequence similarity 184, member B | -4.04938 |
| SAMD4A | sterile alpha motif domain containing 4A | -3.85106 |
| LOC100506374 | uncharacterized LOC100506374 | -3.69651 |
| TSSK3 | testis-specific serine kinase 3 | -3.62808 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein | -3.62008 |
| HIST1H4I | histone cluster 1, H4i | -3.54802 |
| C10ORF95 | chromosome 10 open reading frame 95 | -3.52603 |
| HCN3 | hyperpolarization activated cyclic nucleotide gated potassium channel 3 | -3.43634 |
| HIST1H1C | histone cluster 1, H1c | -3.3971 |
| UQCC3 | ubiquinol-cytochrome c reductase complex assembly factor 3 | -3.38269 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | -3.26983 |
| ATXN2 | ataxin 2 | -3.15844 |
| TMC5 | transmembrane channel-like 5 | -3.11773 |
| LRRC75A | leucine rich repeat containing 75A | -2.99095 |
| OR52D1 | olfactory receptor, family 52, subfamily D, member 1 | -2.99095 |
| CREB1 | cAMP responsive element binding protein 1 | -2.98255 |
| METTL12 | methyltransferase like 12 | -2.98171 |
| KCNIP4 | Kv channel interacting protein 4 | -2.96506 |
| MTFR1L | mitochondrial fission regulator 1-like | -2.90912 |
| PNCK | pregnancy up-regulated nonubiquitous CaM kinase | -2.78377 |
| RPS25 | ribosomal protein S25 | -2.74279 |
| DCPS | decapping enzyme, scavenger | -2.74138 |
| MROH5 | maestro heat-like repeat family member 5 | -2.73971 |
| METTL20 | methyltransferase like 20 | -2.71577 |
| FAM153A | family with sequence similarity 153, member A | -2.67836 |
| EFCAB13 | EF-hand calcium binding domain 13 | -2.6516 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -2.63326 |
| OR51I2 | olfactory receptor, family 51, subfamily I, member 2 | -2.59923 |
| PANK2 | pantothenate kinase 2 | -2.58829 |
| TFIP11 | tuftelin interacting protein 11 | -2.56463 |
| TKFC | triokinase/FMN cyclase | -2.55721 |
| POLG | polymerase (DNA directed), gamma | -2.54127 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | -2.53138 |
| ARMC6 | armadillo repeat containing 6 | -2.48282 |
| SIL1 | SIL1 nucleotide exchange factor | -2.47791 |
| RPS24 | ribosomal protein S24 | -2.45658 |
| LRRC57 | leucine rich repeat containing 57 | -2.43473 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -2.43349 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | -2.41262 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -2.3717 |
| ALOX12 | arachidonate 12-lipoxygenase | -2.30503 |
| GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | -2.27111 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | -2.27066 |
| NRIP2 | nuclear receptor interacting protein 2 | -2.26743 |
| HMGB2 | high mobility group box 2 | -2.24952 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -2.24759 |
| PALLD | palladin, cytoskeletal associated protein | -2.2469 |
| CCDC84 | coiled-coil domain containing 84 | -2.24191 |
| TNRC6C | trinucleotide repeat containing 6C | -2.23066 |
