| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting JMJD1C in Kasumi-1 cell line (Study accession: SRP050058) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_10188_KD_JMJD1C_SRP050058 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTSA | cathepsin A | 20.0 |
| LYZ | lysozyme | 20.0 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 20.0 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 20.0 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 20.0 |
| AZU1 | azurocidin 1 | 20.0 |
| ANXA5 | annexin A5 | 20.0 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | 20.0 |
| ELANE | elastase, neutrophil expressed | 20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 20.0 |
| CTSS | cathepsin S | 20.0 |
| CXORF21 | chromosome X open reading frame 21 | 20.0 |
| RIN2 | Ras and Rab interactor 2 | 20.0 |
| FAM46A | family with sequence similarity 46, member A | 20.0 |
| SLPI | secretory leukocyte peptidase inhibitor | 20.0 |
| CD24 | CD24 molecule | 20.0 |
| SLA | Src-like-adaptor | 20.0 |
| MNDA | myeloid cell nuclear differentiation antigen | 20.0 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 19.699 |
| PRTN3 | proteinase 3 | 19.699 |
| PLXNA4 | plexin A4 | 19.699 |
| CTSD | cathepsin D | 19.1549 |
| IRX3 | iroquois homeobox 3 | 18.284 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 18.0969 |
| TLR2 | toll-like receptor 2 | 18.0757 |
| LIMA1 | LIM domain and actin binding 1 | 17.158 |
| VAMP3 | vesicle-associated membrane protein 3 | 16.8058 |
| LAPTM5 | lysosomal protein transmembrane 5 | 16.5166 |
| GRN | granulin | 16.4118 |
| CFAP47 | cilia and flagella associated protein 47 | 15.5592 |
| NPC2 | Niemann-Pick disease, type C2 | 15.5057 |
| GAPT | GRB2-binding adaptor protein, transmembrane | 15.0481 |
| PIR | pirin (iron-binding nuclear protein) | 14.9706 |
| RGCC | regulator of cell cycle | 14.4961 |
| IQCE | IQ motif containing E | 14.4812 |
| CCDC92 | coiled-coil domain containing 92 | 14.1264 |
| AGTRAP | angiotensin II receptor-associated protein | 13.8761 |
| PSAP | prosaposin | 13.8396 |
| AFF2 | AF4/FMR2 family, member 2 | 13.5974 |
| TRIB2 | tribbles pseudokinase 2 | 13.1537 |
| GCA | grancalcin, EF-hand calcium binding protein | 13.0429 |
| FAM219A | family with sequence similarity 219, member A | 13.0403 |
| SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 | 12.7992 |
| TMSB10 | thymosin beta 10 | 12.6596 |
| ITM2C | integral membrane protein 2C | 12.6596 |
| PIWIL4 | piwi-like RNA-mediated gene silencing 4 | 12.5612 |
| TSPAN7 | tetraspanin 7 | 12.4613 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 12.4435 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 12.426 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 11.7938 |
| GXYLT2 | glucoside xylosyltransferase 2 | 11.7938 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 11.7788 |
| TPRG1L | tumor protein p63 regulated 1-like | 11.3872 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 11.3426 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 10.895 |
| TMEM254 | transmembrane protein 254 | 10.8028 |
| TDRD7 | tudor domain containing 7 | 10.7847 |
| ZDHHC12 | zinc finger, DHHC-type containing 12 | 10.678 |
| KRT10 | keratin 10, type I | 10.6439 |
| NIPAL2 | NIPA-like domain containing 2 | 10.61 |
| TMEM45A | transmembrane protein 45A | 10.4838 |
| NDRG1 | N-myc downstream regulated 1 | 10.4783 |
| CHMP3 | charged multivesicular body protein 3 | 10.4487 |
| TRPC5OS | TRPC5 opposite strand | 10.4249 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 10.4084 |
| CD82 | CD82 molecule | 10.3517 |
| EAF2 | ELL associated factor 2 | 10.3331 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 10.3043 |
| CFAP44 | cilia and flagella associated protein 44 | 10.2356 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 10.1403 |
| COL4A5 | collagen, type IV, alpha 5 | 10.0691 |
| GLRX | glutaredoxin (thioltransferase) | 10.0081 |
| ZMAT1 | zinc finger, matrin-type 1 | 10.0073 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 9.90442 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 9.72148 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 9.69121 |
| PLD4 | phospholipase D family, member 4 | 9.68543 |
| VAMP8 | vesicle-associated membrane protein 8 | 9.51555 |
| ERLIN1 | ER lipid raft associated 1 | 9.4205 |
| CST3 | cystatin C | 9.35754 |
| CD53 | CD53 molecule | 9.29213 |
| ZNF608 | zinc finger protein 608 | 9.27047 |
| IRX5 | iroquois homeobox 5 | 9.24441 |
| CTSG | cathepsin G | 8.98224 |
| MFSD1 | major facilitator superfamily domain containing 1 | 8.95519 |
| SAMD9L | sterile alpha motif domain containing 9-like | 8.93322 |
| AIFM2 | apoptosis-inducing factor, mitochondrion-associated, 2 | 8.70324 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 8.57907 |
| AP5B1 | adaptor-related protein complex 5, beta 1 subunit | 8.40926 |
| C19ORF54 | chromosome 19 open reading frame 54 | 8.36295 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 8.25389 |
| CD4 | CD4 molecule | 8.193 |
| LMO7 | LIM domain 7 | 8.18303 |
| HRH2 | histamine receptor H2 | 8.18137 |
| ZC3H12D | zinc finger CCCH-type containing 12D | 8.11612 |
| MYADM | myeloid-associated differentiation marker | 8.10835 |
| SIRPA | signal-regulatory protein alpha | 8.09701 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 8.0657 |
| CD33 | CD33 molecule | 8.04896 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | 7.74153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HPSE | heparanase | -20.0 |
| SFXN1 | sideroflexin 1 | -20.0 |
| TPSD1 | tryptase delta 1 | -20.0 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | -20.0 |
| MPL | MPL proto-oncogene, thrombopoietin receptor | -20.0 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -20.0 |
| ASS1 | argininosuccinate synthase 1 | -20.0 |
| ETV4 | ets variant 4 | -20.0 |
| ETV5 | ets variant 5 | -20.0 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | -20.0 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -20.0 |
| OLFML2A | olfactomedin-like 2A | -20.0 |
| SETD7 | SET domain containing (lysine methyltransferase) 7 | -20.0 |
| NPR3 | natriuretic peptide receptor 3 | -20.0 |
| HMGA2 | high mobility group AT-hook 2 | -20.0 |
| CD109 | CD109 molecule | -20.0 |
| JMJD1C | jumonji domain containing 1C | -20.0 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -20.0 |
| PLCH1 | phospholipase C, eta 1 | -20.0 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -20.0 |
| TRIQK | triple QxxK/R motif containing | -20.0 |
| GPX7 | glutathione peroxidase 7 | -20.0 |
| FKBP5 | FK506 binding protein 5 | -20.0 |
| ADGRG3 | adhesion G protein-coupled receptor G3 | -20.0 |
| BZW1 | basic leucine zipper and W2 domains 1 | -20.0 |
| DUSP6 | dual specificity phosphatase 6 | -20.0 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -20.0 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -20.0 |
| DOK4 | docking protein 4 | -20.0 |
| MRC2 | mannose receptor, C type 2 | -20.0 |
| S100P | S100 calcium binding protein P | -20.0 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -20.0 |
| ADGRB1 | adhesion G protein-coupled receptor B1 | -20.0 |
| KLF10 | Kruppel-like factor 10 | -20.0 |
| TMEM194A | transmembrane protein 194A | -20.0 |
| TMEM14C | transmembrane protein 14C | -20.0 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -20.0 |
| MYRF | myelin regulatory factor | -20.0 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -20.0 |
| PADI3 | peptidyl arginine deiminase, type III | -20.0 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -20.0 |
| MTFR1 | mitochondrial fission regulator 1 | -20.0 |
| SETBP1 | SET binding protein 1 | -20.0 |
| PHGDH | phosphoglycerate dehydrogenase | -20.0 |
| AFAP1L1 | actin filament associated protein 1-like 1 | -20.0 |
| RAB27B | RAB27B, member RAS oncogene family | -20.0 |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | -20.0 |
| EGR1 | early growth response 1 | -20.0 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -20.0 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -20.0 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -20.0 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -20.0 |
| ADAM10 | ADAM metallopeptidase domain 10 | -20.0 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -20.0 |
| RAB40B | RAB40B, member RAS oncogene family | -20.0 |
| NOG | noggin | -20.0 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -20.0 |
| STAB1 | stabilin 1 | -20.0 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -20.0 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -19.699 |
| PALM2-AKAP2 | PALM2-AKAP2 readthrough | -19.699 |
| TPSAB1 | tryptase alpha/beta 1 | -19.699 |
| LMAN1 | lectin, mannose-binding, 1 | -19.5229 |
| FAM96B | family with sequence similarity 96, member B | -19.3979 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -19.1549 |
| AIF1 | allograft inflammatory factor 1 | -19.0458 |
| TTC29 | tetratricopeptide repeat domain 29 | -19.0458 |
| ESAM | endothelial cell adhesion molecule | -19.0 |
| MAPK8 | mitogen-activated protein kinase 8 | -18.9208 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -18.8861 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | -18.7696 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -18.6383 |
| TMEM14B | transmembrane protein 14B | -18.4318 |
| RMI2 | RecQ mediated genome instability 2 | -18.3768 |
| GSR | glutathione reductase | -18.3372 |
| INSIG1 | insulin induced gene 1 | -18.1549 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | -18.0969 |
| UNC13D | unc-13 homolog D (C. elegans) | -18.0269 |
| ADSS | adenylosuccinate synthase | -17.7878 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -17.7399 |
| IL1RAP | interleukin 1 receptor accessory protein | -17.644 |
| PRDM8 | PR domain containing 8 | -17.2434 |
| GPR32 | G protein-coupled receptor 32 | -17.2351 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | -17.1549 |
| NPTX1 | neuronal pentraxin I | -16.8626 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -16.8058 |
| MMP28 | matrix metallopeptidase 28 | -16.4645 |
| RLTPR | RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing | -16.3903 |
| SECISBP2 | SECIS binding protein 2 | -16.3787 |
| KIF5B | kinesin family member 5B | -16.2434 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 | -16.0776 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -15.9478 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | -15.8817 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | -15.8622 |
| OSTC | oligosaccharyltransferase complex subunit (non-catalytic) | -15.8542 |
| ITPRIPL1 | inositol 1,4,5-trisphosphate receptor interacting protein-like 1 | -15.8445 |
| ATP11C | ATPase, class VI, type 11C | -15.8409 |
| CHKB | choline kinase beta | -15.7956 |
| GUCY2C | guanylate cyclase 2C | -15.7678 |
| NLRC5 | NLR family, CARD domain containing 5 | -15.7006 |
