Perturb_10663_OE_HSPB3_SRP288471 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting HSPB3 in LHCN-M2 cell line (Study accession: SRP288471) (PerturbAtlas)
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Genes

62 genes differentially expressed following the Perturb_10663_OE_HSPB3_SRP288471 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
MARS methionyl-tRNA synthetase 4.49112
PCED1B PC-esterase domain containing 1B 4.38327
FHOD1 formin homology 2 domain containing 1 3.46071
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 3.11126
CARHSP1 calcium regulated heat stable protein 1, 24kDa 1.98354
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.9683
MSC musculin 1.9683
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.73848
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 1.64521
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.57545
FAM168A family with sequence similarity 168, member A 1.56764
C19ORF60 chromosome 19 open reading frame 60 1.52778
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 1.41107

decreased expression

Symbol Name Standardized Value
CCR7 chemokine (C-C motif) receptor 7 -13.514
BAIAP2L1 BAI1-associated protein 2-like 1 -6.72491
ZBTB48 zinc finger and BTB domain containing 48 -6.30244
DNAH10 dynein, axonemal, heavy chain 10 -5.96932
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -5.42957
WDR20 WD repeat domain 20 -4.50684
SPEN spen family transcriptional repressor -4.00646
FANCC Fanconi anemia, complementation group C -3.96312
GPX3 glutathione peroxidase 3 -3.38561
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 -3.19448
CCDC85B coiled-coil domain containing 85B -2.90516
FGF14 fibroblast growth factor 14 -2.86273
IL16 interleukin 16 -2.70763
VEPH1 ventricular zone expressed PH domain-containing 1 -2.437
TBC1D20 TBC1 domain family, member 20 -2.31153
QRFP pyroglutamylated RFamide peptide -2.25989
SH3D21 SH3 domain containing 21 -2.1897
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -2.1897
FSIP1 fibrous sheath interacting protein 1 -2.1588
MAPK8 mitogen-activated protein kinase 8 -2.13431
ARMC7 armadillo repeat containing 7 -1.9683
ZNF771 zinc finger protein 771 -1.91384
DEXI Dexi homolog (mouse) -1.9087
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -1.80537
ABR active BCR-related -1.76382
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.74594
MROH1 maestro heat-like repeat family member 1 -1.67416
CDK10 cyclin-dependent kinase 10 -1.65497
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -1.64521
LRRC75A leucine rich repeat containing 75A -1.62097
TUBGCP6 tubulin, gamma complex associated protein 6 -1.61677
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -1.59707
TSPAN31 tetraspanin 31 -1.57545
C11ORF48 -1.56764
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -1.56196
LYPD1 LY6/PLAUR domain containing 1 -1.53276
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) -1.50454
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -1.47571
SZT2 seizure threshold 2 homolog (mouse) -1.43156
DMAP1 DNA methyltransferase 1 associated protein 1 -1.4121
RHOF ras homolog family member F (in filopodia) -1.4118
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -1.40101
SLC38A10 solute carrier family 38, member 10 -1.40101
NF1 neurofibromin 1 -1.40101
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -1.39094
MTBP MDM2 binding protein -1.35192
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -1.33101
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) -1.32732
C14ORF166 chromosome 14 open reading frame 166 -1.31875