Perturb_1078_OE_ZBED2_SRP235000 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description OE perturbation targeting ZBED2 in AsPC-1 cell line (Study accession: SRP235000) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_1078_OE_ZBED2_SRP235000 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
ZFP36L1 ZFP36 ring finger protein-like 1 20.0
CABLES1 Cdk5 and Abl enzyme substrate 1 20.0
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 20.0
LAMC2 laminin, gamma 2 20.0
IRAK2 interleukin-1 receptor-associated kinase 2 20.0
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 20.0
TM4SF1 transmembrane 4 L six family member 1 20.0
AKR1C2 aldo-keto reductase family 1, member C2 20.0
PLIN2 perilipin 2 20.0
PTGES prostaglandin E synthase 20.0
AKR1C3 aldo-keto reductase family 1, member C3 20.0
SQSTM1 sequestosome 1 20.0
FAM65C family with sequence similarity 65, member C 20.0
MSN moesin 20.0
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 20.0
GNG11 guanine nucleotide binding protein (G protein), gamma 11 20.0
KYNU kynureninase 20.0
PLK2 polo-like kinase 2 20.0
TNS3 tensin 3 20.0
CXCL5 chemokine (C-X-C motif) ligand 5 20.0
BIRC3 baculoviral IAP repeat containing 3 20.0
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 20.0
TNIP1 TNFAIP3 interacting protein 1 20.0
AKR1C1 aldo-keto reductase family 1, member C1 20.0
CLU clusterin 20.0
NPM3 nucleophosmin/nucleoplasmin 3 20.0
C3 complement component 3 20.0
KIAA1551 KIAA1551 20.0
CSF1 colony stimulating factor 1 (macrophage) 20.0
TXNRD1 thioredoxin reductase 1 20.0
FIBP fibroblast growth factor (acidic) intracellular binding protein 20.0
IFNGR1 interferon gamma receptor 1 20.0
KRT80 keratin 80, type II 20.0
C6ORF141 chromosome 6 open reading frame 141 20.0
MYH9 myosin, heavy chain 9, non-muscle 20.0
GPX4 glutathione peroxidase 4 20.0
PHLDB2 pleckstrin homology-like domain, family B, member 2 20.0
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 20.0
DNMBP dynamin binding protein 20.0
AKAP12 A kinase (PRKA) anchor protein 12 20.0
AJUBA ajuba LIM protein 20.0
SOX4 SRY (sex determining region Y)-box 4 20.0
SCARA3 scavenger receptor class A, member 3 20.0
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 20.0
CLDN1 claudin 1 20.0
VIM vimentin 20.0
RPL10 ribosomal protein L10 20.0
PDZK1IP1 PDZK1 interacting protein 1 20.0
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 20.0
PTRF polymerase I and transcript release factor 20.0
ITGAV integrin, alpha V 20.0
USB1 U6 snRNA biogenesis 1 20.0
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 20.0
ITM2C integral membrane protein 2C 20.0
LCN2 lipocalin 2 20.0
DUOX2 dual oxidase 2 20.0
STAMBPL1 STAM binding protein-like 1 20.0
VNN1 vanin 1 20.0
SYNE1 spectrin repeat containing, nuclear envelope 1 20.0
FLNA filamin A, alpha 20.0
SMAD6 SMAD family member 6 20.0
CBX6 chromobox homolog 6 20.0
TMSB4X thymosin beta 4, X-linked 20.0
WNT7B wingless-type MMTV integration site family, member 7B 20.0
PLTP phospholipid transfer protein 20.0
CCNA2 cyclin A2 20.0
TM4SF18 transmembrane 4 L six family member 18 20.0
FTL ferritin, light polypeptide 20.0
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 20.0
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 20.0
KIFC3 kinesin family member C3 20.0
ZC3H12A zinc finger CCCH-type containing 12A 20.0
UGDH UDP-glucose 6-dehydrogenase 20.0
CPVL carboxypeptidase, vitellogenic-like 20.0
SMAD3 SMAD family member 3 20.0
IGFBP3 insulin-like growth factor binding protein 3 20.0
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 20.0
IL32 interleukin 32 20.0
RDH10 retinol dehydrogenase 10 (all-trans) 20.0
COTL1 coactosin-like F-actin binding protein 1 20.0
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 20.0
UBASH3B ubiquitin associated and SH3 domain containing B 20.0
PRDM8 PR domain containing 8 20.0
NCEH1 neutral cholesterol ester hydrolase 1 20.0
VCL vinculin 20.0
LGALS1 lectin, galactoside-binding, soluble, 1 20.0
ZBED2 zinc finger, BED-type containing 2 20.0
COL5A2 collagen, type V, alpha 2 20.0
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 20.0
IGFBP1 insulin-like growth factor binding protein 1 20.0
TMEM132A transmembrane protein 132A 20.0
CCL20 chemokine (C-C motif) ligand 20 20.0
SDPR serum deprivation response 20.0
CAV1 caveolin 1, caveolae protein, 22kDa 20.0
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 20.0
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 20.0
NAV3 neuron navigator 3 20.0
NAP1L1 nucleosome assembly protein 1-like 1 20.0
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 20.0
ZFAND5 zinc finger, AN1-type domain 5 20.0

decreased expression

Symbol Name Standardized Value
DEAF1 DEAF1 transcription factor -20.0
DSG3 desmoglein 3 -20.0
MUC5B mucin 5B, oligomeric mucus/gel-forming -20.0
GJB1 gap junction protein, beta 1, 32kDa -20.0
DPEP1 dipeptidase 1 (renal) -20.0
TMEM151A transmembrane protein 151A -20.0
TM4SF5 transmembrane 4 L six family member 5 -20.0
FAM46A family with sequence similarity 46, member A -20.0
METRNL meteorin, glial cell differentiation regulator-like -20.0
IGFL2 IGF-like family member 2 -20.0
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -20.0
SLC16A4 solute carrier family 16, member 4 -20.0
PLXNB3 plexin B3 -20.0
KIAA1161 KIAA1161 -20.0
MARVELD2 MARVEL domain containing 2 -20.0
NR4A1 nuclear receptor subfamily 4, group A, member 1 -20.0
RTP4 receptor (chemosensory) transporter protein 4 -20.0
ASS1 argininosuccinate synthase 1 -20.0
ATP2A3 ATPase, Ca++ transporting, ubiquitous -20.0
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -20.0
MMP28 matrix metallopeptidase 28 -20.0
WWC3 WWC family member 3 -20.0
ARRDC4 arrestin domain containing 4 -20.0
C2ORF88 chromosome 2 open reading frame 88 -20.0
CDH3 cadherin 3, type 1, P-cadherin (placental) -20.0
MEGF6 multiple EGF-like-domains 6 -20.0
RNF144A ring finger protein 144A -20.0
NOXA1 NADPH oxidase activator 1 -20.0
PMP22 peripheral myelin protein 22 -20.0
OCLN occludin -20.0
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -20.0
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -20.0
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -20.0
TMIGD1 transmembrane and immunoglobulin domain containing 1 -20.0
HTRA1 HtrA serine peptidase 1 -20.0
GRAMD4 GRAM domain containing 4 -20.0
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -20.0
PRR15 proline rich 15 -20.0
NHSL1 NHS-like 1 -20.0
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -20.0
FA2H fatty acid 2-hydroxylase -20.0
BLACAT1 bladder cancer associated transcript 1 (non-protein coding) -20.0
RTCA RNA 3'-terminal phosphate cyclase -20.0
ACOT1 acyl-CoA thioesterase 1 -20.0
CLDN2 claudin 2 -20.0
RAB11FIP4 RAB11 family interacting protein 4 (class II) -20.0
SH3PXD2A SH3 and PX domains 2A -20.0
CGREF1 cell growth regulator with EF-hand domain 1 -20.0
LMF1 lipase maturation factor 1 -20.0
PARVB parvin, beta -20.0
PHACTR3 phosphatase and actin regulator 3 -20.0
OBSL1 obscurin-like 1 -20.0
PLLP plasmolipin -20.0
ALS2CL ALS2 C-terminal like -20.0
FOS FBJ murine osteosarcoma viral oncogene homolog -20.0
TYSND1 trypsin domain containing 1 -20.0
THNSL2 threonine synthase-like 2 (S. cerevisiae) -20.0
NIPAL2 NIPA-like domain containing 2 -20.0
FBP1 fructose-1,6-bisphosphatase 1 -20.0
WFDC2 WAP four-disulfide core domain 2 -20.0
C1ORF233 chromosome 1 open reading frame 233 -20.0
KLK6 kallikrein-related peptidase 6 -20.0
C6ORF132 chromosome 6 open reading frame 132 -20.0
MXRA8 matrix-remodelling associated 8 -20.0
GSDMB gasdermin B -20.0
DDIT4 DNA-damage-inducible transcript 4 -20.0
UNC5B unc-5 homolog B (C. elegans) -20.0
PCSK9 proprotein convertase subtilisin/kexin type 9 -20.0
PGLS 6-phosphogluconolactonase -20.0
HLA-F major histocompatibility complex, class I, F -20.0
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -20.0
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -20.0
CTSL cathepsin L -20.0
MLXIPL MLX interacting protein-like -20.0
EVA1C eva-1 homolog C (C. elegans) -20.0
GANC glucosidase, alpha; neutral C -20.0
XYLT1 xylosyltransferase I -20.0
LAMP3 lysosomal-associated membrane protein 3 -20.0
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -20.0
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -20.0
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 -20.0
PDGFA platelet-derived growth factor alpha polypeptide -20.0
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 -20.0
UROS uroporphyrinogen III synthase -20.0
AOC1 amine oxidase, copper containing 1 -20.0
VIPR1 vasoactive intestinal peptide receptor 1 -20.0
CARNS1 carnosine synthase 1 -20.0
PRR15L proline rich 15-like -20.0
FOSB FBJ murine osteosarcoma viral oncogene homolog B -20.0
ESRP1 epithelial splicing regulatory protein 1 -20.0
RSAD2 radical S-adenosyl methionine domain containing 2 -20.0
PKD2 polycystic kidney disease 2 (autosomal dominant) -20.0
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -20.0
KRT9 keratin 9, type I -20.0
FAM132B family with sequence similarity 132, member B -20.0
TTBK1 tau tubulin kinase 1 -20.0
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -20.0
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -20.0
ONECUT3 one cut homeobox 3 -20.0
DHRS9 dehydrogenase/reductase (SDR family) member 9 -20.0