Perturb_11356_KD_MAP3K7_SRP310158 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting MAP3K7 in LNCaP cell line (Study accession: SRP310158) (PerturbAtlas)
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Genes

18 genes differentially expressed following the Perturb_11356_KD_MAP3K7_SRP310158 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
TMEM186 transmembrane protein 186 3.03969
HPS3 Hermansky-Pudlak syndrome 3 3.03374
PCNXL4 pecanex-like 4 (Drosophila) 2.73133
CCDC154 coiled-coil domain containing 154 1.9532
SNED1 sushi, nidogen and EGF-like domains 1 1.92955
RIMS1 regulating synaptic membrane exocytosis 1 1.77197
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.53825
MPI mannose phosphate isomerase 1.3082

decreased expression

Symbol Name Standardized Value
C5ORF45 chromosome 5 open reading frame 45 -8.18841
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -3.06206
GPS2 G protein pathway suppressor 2 -3.03374
HIST1H1E histone cluster 1, H1e -2.19987
LOC122455342 testis-specific serine/proline-rich protein -1.9187
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.90389
PTMA prothymosin, alpha -1.77197
RPS18 ribosomal protein S18 -1.60897
ATG7 autophagy related 7 -1.4936
BEST1 bestrophin 1 -1.35834