| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting USP7 in LNCaP cell line (Study accession: SRP292689) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_11394_KD_USP7_SRP292689 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLF2 | myeloid leukemia factor 2 | 20.0 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 20.0 |
| RPLP1 | ribosomal protein, large, P1 | 20.0 |
| NCOR2 | nuclear receptor corepressor 2 | 20.0 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 20.0 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 20.0 |
| SON | SON DNA binding protein | 20.0 |
| CPNE3 | copine III | 20.0 |
| CD164 | CD164 molecule, sialomucin | 20.0 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 20.0 |
| FAM83H | family with sequence similarity 83, member H | 20.0 |
| PLXNB2 | plexin B2 | 20.0 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 20.0 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 20.0 |
| TTC3 | tetratricopeptide repeat domain 3 | 20.0 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 20.0 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 20.0 |
| WSB2 | WD repeat and SOCS box containing 2 | 20.0 |
| CANT1 | calcium activated nucleotidase 1 | 20.0 |
| USP54 | ubiquitin specific peptidase 54 | 20.0 |
| BSG | basigin (Ok blood group) | 20.0 |
| MARCKSL1 | MARCKS-like 1 | 20.0 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 20.0 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 20.0 |
| EFNA5 | ephrin-A5 | 20.0 |
| EPN1 | epsin 1 | 20.0 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 20.0 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 20.0 |
| GPX1 | glutathione peroxidase 1 | 20.0 |
| LAMA3 | laminin, alpha 3 | 20.0 |
| GOLM1 | golgi membrane protein 1 | 20.0 |
| KIF5B | kinesin family member 5B | 20.0 |
| RPS2 | ribosomal protein S2 | 20.0 |
| CCNL2 | cyclin L2 | 20.0 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 20.0 |
| FKBP8 | FK506 binding protein 8, 38kDa | 20.0 |
| MYO6 | myosin VI | 20.0 |
| TBX3 | T-box 3 | 20.0 |
| ADAR | adenosine deaminase, RNA-specific | 20.0 |
| PLEC | plectin | 20.0 |
| SOX4 | SRY (sex determining region Y)-box 4 | 20.0 |
| FAM210B | family with sequence similarity 210, member B | 20.0 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 20.0 |
| CLDN4 | claudin 4 | 20.0 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 20.0 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 20.0 |
| GDF15 | growth differentiation factor 15 | 20.0 |
| MYH10 | myosin, heavy chain 10, non-muscle | 20.0 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 20.0 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 20.0 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 20.0 |
| WDR1 | WD repeat domain 1 | 20.0 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 20.0 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 20.0 |
| SERINC5 | serine incorporator 5 | 20.0 |
| ADAM9 | ADAM metallopeptidase domain 9 | 20.0 |
| TNKS1BP1 | tankyrase 1 binding protein 1, 182kDa | 20.0 |
| GRB10 | growth factor receptor-bound protein 10 | 20.0 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 20.0 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 20.0 |
| PSAP | prosaposin | 20.0 |
| DSC2 | desmocollin 2 | 20.0 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | 20.0 |
| GOLGB1 | golgin B1 | 20.0 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 20.0 |
| NPC1 | Niemann-Pick disease, type C1 | 20.0 |
| ODC1 | ornithine decarboxylase 1 | 20.0 |
| ACTN4 | actinin, alpha 4 | 20.0 |
| YBX3 | Y box binding protein 3 | 20.0 |
| KIAA0100 | KIAA0100 | 20.0 |
| SYNGR2 | synaptogyrin 2 | 20.0 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 20.0 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 20.0 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 20.0 |
| TMEM132A | transmembrane protein 132A | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| JUP | junction plakoglobin | 20.0 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 20.0 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 20.0 |
| CALD1 | caldesmon 1 | 20.0 |
| KIF1C | kinesin family member 1C | 20.0 |
| RHOB | ras homolog family member B | 20.0 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 20.0 |
| PROM2 | prominin 2 | 20.0 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 20.0 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | 20.0 |
| UBAP2L | ubiquitin associated protein 2-like | 20.0 |
| ZNF217 | zinc finger protein 217 | 20.0 |
| AHCY | adenosylhomocysteinase | 20.0 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 20.0 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 20.0 |
| MIA3 | melanoma inhibitory activity family, member 3 | 20.0 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 20.0 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 20.0 |
| CMTM4 | CKLF-like MARVEL transmembrane domain containing 4 | 20.0 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 20.0 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 20.0 |
| ENDOD1 | endonuclease domain containing 1 | 20.0 |
| USP22 | ubiquitin specific peptidase 22 | 20.0 |
| INTS1 | integrator complex subunit 1 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -20.0 |
| FAM129A | family with sequence similarity 129, member A | -20.0 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -20.0 |
| TERT | telomerase reverse transcriptase | -20.0 |
| KIAA0101 | KIAA0101 | -20.0 |
| PDIA2 | protein disulfide isomerase family A, member 2 | -20.0 |
| PPARGC1B | peroxisome proliferator-activated receptor gamma, coactivator 1 beta | -20.0 |
| KREMEN2 | kringle containing transmembrane protein 2 | -20.0 |
| EXO1 | exonuclease 1 | -20.0 |
| CARD10 | caspase recruitment domain family, member 10 | -20.0 |
| LINC00514 | long intergenic non-protein coding RNA 514 | -20.0 |
| CRISP3 | cysteine-rich secretory protein 3 | -20.0 |
| CEP152 | centrosomal protein 152kDa | -20.0 |
| LRG1 | leucine-rich alpha-2-glycoprotein 1 | -20.0 |
| NMU | neuromedin U | -20.0 |
| NT5M | 5',3'-nucleotidase, mitochondrial | -20.0 |
| KIF24 | kinesin family member 24 | -20.0 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -20.0 |
| ZGRF1 | zinc finger, GRF-type containing 1 | -20.0 |
| PKN3 | protein kinase N3 | -20.0 |
| GSG2 | germ cell associated 2 (haspin) | -20.0 |
| HAUS8 | HAUS augmin-like complex, subunit 8 | -20.0 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -20.0 |
| FBXO5 | F-box protein 5 | -20.0 |
| RTKN2 | rhotekin 2 | -20.0 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -20.0 |
| MRPL36 | mitochondrial ribosomal protein L36 | -20.0 |
| SAMD13 | sterile alpha motif domain containing 13 | -20.0 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -20.0 |
| BLM | Bloom syndrome, RecQ helicase-like | -20.0 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -20.0 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | -20.0 |
| JADE2 | jade family PHD finger 2 | -20.0 |
| OR51E1 | olfactory receptor, family 51, subfamily E, member 1 | -20.0 |
| GPX8 | glutathione peroxidase 8 (putative) | -20.0 |
| RCAN3 | RCAN family member 3 | -20.0 |
| TMEM56 | transmembrane protein 56 | -20.0 |
| ORC1 | origin recognition complex, subunit 1 | -20.0 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -20.0 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -20.0 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -20.0 |
| E2F2 | E2F transcription factor 2 | -20.0 |
| E2F8 | E2F transcription factor 8 | -20.0 |
| IFITM2 | interferon induced transmembrane protein 2 | -20.0 |
| PRSS16 | protease, serine, 16 (thymus) | -20.0 |
| DNASE2B | deoxyribonuclease II beta | -20.0 |
| CENPA | centromere protein A | -20.0 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | -20.0 |
| LRRCC1 | leucine rich repeat and coiled-coil centrosomal protein 1 | -20.0 |
| KIAA0040 | KIAA0040 | -20.0 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -20.0 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | -20.0 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -20.0 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -20.0 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -20.0 |
| NRM | nurim (nuclear envelope membrane protein) | -20.0 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -20.0 |
| SALL2 | spalt-like transcription factor 2 | -20.0 |
| RAD51D | RAD51 paralog D | -20.0 |
| GALK1 | galactokinase 1 | -20.0 |
| ALPK1 | alpha-kinase 1 | -20.0 |
| CTSV | cathepsin V | -20.0 |
| CTSC | cathepsin C | -20.0 |
| TRIM2 | tripartite motif containing 2 | -20.0 |
| GSDMB | gasdermin B | -20.0 |
| BHLHA15 | basic helix-loop-helix family, member a15 | -20.0 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -20.0 |
| RMI2 | RecQ mediated genome instability 2 | -20.0 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -20.0 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -20.0 |
| GAS2L3 | growth arrest-specific 2 like 3 | -20.0 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | -20.0 |
| SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 | -20.0 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -20.0 |
| TMEM107 | transmembrane protein 107 | -20.0 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | -20.0 |
| ALG10 | ALG10, alpha-1,2-glucosyltransferase | -20.0 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -20.0 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -20.0 |
| FAM72B | family with sequence similarity 72, member B | -20.0 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -20.0 |
| VEGFB | vascular endothelial growth factor B | -20.0 |
| CENPI | centromere protein I | -20.0 |
| CENPW | centromere protein W | -20.0 |
| CENPQ | centromere protein Q | -20.0 |
| DNHD1 | dynein heavy chain domain 1 | -20.0 |
| SCLT1 | sodium channel and clathrin linker 1 | -20.0 |
| DBF4B | DBF4 zinc finger B | -20.0 |
| KIF18A | kinesin family member 18A | -20.0 |
| ACBD7 | acyl-CoA binding domain containing 7 | -20.0 |
| DOC2A | double C2-like domains, alpha | -20.0 |
| WDR76 | WD repeat domain 76 | -20.0 |
| FZD4 | frizzled class receptor 4 | -20.0 |
| AOC3 | amine oxidase, copper containing 3 | -20.0 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -20.0 |
| PAQR4 | progestin and adipoQ receptor family member IV | -20.0 |
| C18ORF54 | chromosome 18 open reading frame 54 | -20.0 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -20.0 |
| CDC25C | cell division cycle 25C | -20.0 |
| RAD51 | RAD51 recombinase | -20.0 |
