| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CPT1A in LNCaP cell line (Study accession: SRP076884) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_11403_KD_CPT1A_SRP076884 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MPI | mannose phosphate isomerase | 20.0 |
| AMDHD2 | amidohydrolase domain containing 2 | 20.0 |
| SPON2 | spondin 2, extracellular matrix protein | 20.0 |
| PLEKHH1 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 | 20.0 |
| MARS | methionyl-tRNA synthetase | 20.0 |
| C5ORF45 | chromosome 5 open reading frame 45 | 20.0 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 20.0 |
| TBPL1 | TBP-like 1 | 20.0 |
| C7ORF49 | chromosome 7 open reading frame 49 | 20.0 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 20.0 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | 20.0 |
| UNC5C | unc-5 homolog C (C. elegans) | 20.0 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 20.0 |
| BEST1 | bestrophin 1 | 19.5229 |
| CTBP1 | C-terminal binding protein 1 | 17.9872 |
| SPATA1 | spermatogenesis associated 1 | 16.2342 |
| CD27 | CD27 molecule | 15.2614 |
| DOPEY1 | dopey family member 1 | 14.4306 |
| MIA3 | melanoma inhibitory activity family, member 3 | 14.103 |
| CCDC152 | coiled-coil domain containing 152 | 14.0986 |
| THBS1 | thrombospondin 1 | 13.5903 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 12.4458 |
| MARCH7 | membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase | 12.2957 |
| FIZ1 | FLT3-interacting zinc finger 1 | 11.8323 |
| IDUA | iduronidase, alpha-L- | 11.558 |
| ABHD16B | abhydrolase domain containing 16B | 10.4068 |
| NXPH4 | neurexophilin 4 | 10.351 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 10.2005 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 10.1196 |
| CPLX1 | complexin 1 | 10.0867 |
| TSEN54 | TSEN54 tRNA splicing endonuclease subunit | 9.56354 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 9.26703 |
| SERINC4 | serine incorporator 4 | 9.20981 |
| ZNF135 | zinc finger protein 135 | 9.09026 |
| FRMD3 | FERM domain containing 3 | 8.9298 |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa | 8.91599 |
| MUS81 | MUS81 structure-specific endonuclease subunit | 8.65613 |
| ARHGAP30 | Rho GTPase activating protein 30 | 8.39665 |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 | 8.23155 |
| ANGPTL6 | angiopoietin-like 6 | 8.14411 |
| BHMT | betaine--homocysteine S-methyltransferase | 7.9375 |
| KLC4 | kinesin light chain 4 | 7.92061 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 7.87076 |
| HEATR1 | HEAT repeat containing 1 | 7.77396 |
| WTAP | Wilms tumor 1 associated protein | 7.74117 |
| MXRA8 | matrix-remodelling associated 8 | 7.692 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 7.61116 |
| SIRT5 | sirtuin 5 | 7.41073 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 7.39587 |
| C2ORF16 | chromosome 2 open reading frame 16 | 7.39256 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 7.22464 |
| PGM3 | phosphoglucomutase 3 | 7.17801 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 7.17784 |
| H2AFY | H2A histone family, member Y | 7.02617 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) | 6.92355 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 6.91464 |
| PPID | peptidylprolyl isomerase D | 6.85974 |
| LRRC75A | leucine rich repeat containing 75A | 6.58526 |
| HIST1H2BN | histone cluster 1, H2bn | 6.55164 |
| EVA1B | eva-1 homolog B (C. elegans) | 6.46788 |
| ZFHX3 | zinc finger homeobox 3 | 6.38996 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 6.3333 |
| PEX10 | peroxisomal biogenesis factor 10 | 6.29949 |
| ENG | endoglin | 6.2503 |
| SIPA1 | signal-induced proliferation-associated 1 | 6.15126 |
| FBXO22 | F-box protein 22 | 6.04894 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 5.96798 |
| ADAM17 | ADAM metallopeptidase domain 17 | 5.94146 |
| CCDC176 | coiled-coil domain containing 176 | 5.85516 |
| DNASE1L2 | deoxyribonuclease I-like 2 | 5.75851 |
| ATG9B | autophagy related 9B | 5.67282 |
| C14ORF93 | chromosome 14 open reading frame 93 | 5.59138 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 5.50245 |
| QRICH2 | glutamine rich 2 | 5.37611 |
| POLH | polymerase (DNA directed), eta | 5.23813 |
| HDAC9 | histone deacetylase 9 | 5.21566 |
| HDDC2 | HD domain containing 2 | 5.19011 |
| KIAA0226 | KIAA0226 | 5.15094 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 5.14315 |
| CHDH | choline dehydrogenase | 5.10979 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | 5.10979 |
| FAM71E1 | family with sequence similarity 71, member E1 | 5.08512 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 5.06198 |
| THBS2 | thrombospondin 2 | 5.00749 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | 4.88057 |
| JMJD4 | jumonji domain containing 4 | 4.8667 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 4.83988 |
| HBP1 | HMG-box transcription factor 1 | 4.83497 |
| ZBTB45 | zinc finger and BTB domain containing 45 | 4.78639 |
| SRMS | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites | 4.77376 |
| NEIL2 | nei endonuclease VIII-like 2 (E. coli) | 4.74692 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 4.69866 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 4.65569 |
| XPO1 | exportin 1 | 4.6161 |
| ZNF175 | zinc finger protein 175 | 4.61027 |
| COG5 | component of oligomeric golgi complex 5 | 4.5625 |
| LRRC14 | leucine rich repeat containing 14 | 4.54046 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 4.53672 |
| ATG7 | autophagy related 7 | 4.52885 |
| PTGR2 | prostaglandin reductase 2 | 4.50304 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POLG | polymerase (DNA directed), gamma | -20.0 |
| ERCC1 | excision repair cross-complementation group 1 | -20.0 |
| HIST1H4I | histone cluster 1, H4i | -20.0 |
| FAM166A | family with sequence similarity 166, member A | -20.0 |
| SRR | serine racemase | -20.0 |
| PCNXL4 | pecanex-like 4 (Drosophila) | -20.0 |
| TTI2 | TELO2 interacting protein 2 | -20.0 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | -20.0 |
| LRRC41 | leucine rich repeat containing 41 | -20.0 |
| LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | -20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -20.0 |
| EXOSC9 | exosome component 9 | -20.0 |
| PAQR4 | progestin and adipoQ receptor family member IV | -20.0 |
| FADS1 | fatty acid desaturase 1 | -20.0 |
| MXD3 | MAX dimerization protein 3 | -20.0 |
| CIRBP | cold inducible RNA binding protein | -20.0 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | -20.0 |
| ENOSF1 | enolase superfamily member 1 | -20.0 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -20.0 |
| VPRBP | Vpr (HIV-1) binding protein | -20.0 |
| MLX | MLX, MAX dimerization protein | -20.0 |
| ASB6 | ankyrin repeat and SOCS box containing 6 | -20.0 |
| NARFL | nuclear prelamin A recognition factor-like | -20.0 |
| CCDC107 | coiled-coil domain containing 107 | -20.0 |
| LOC122455342 | testis-specific serine/proline-rich protein | -20.0 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | -20.0 |
| SNX22 | sorting nexin 22 | -20.0 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -20.0 |
| PLLP | plasmolipin | -20.0 |
| CCDC73 | coiled-coil domain containing 73 | -20.0 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 | -19.699 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 | -19.3979 |
| C14ORF79 | chromosome 14 open reading frame 79 | -19.301 |
| E2F5 | E2F transcription factor 5, p130-binding | -18.2366 |
| DDTL | D-dopachrome tautomerase-like | -18.0269 |
| SLA2 | Src-like-adaptor 2 | -17.9318 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 | -17.6021 |
| TEX2 | testis expressed 2 | -17.4724 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -17.3054 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 | -17.0367 |
| CLCC1 | chloride channel CLIC-like 1 | -16.8684 |
| TECPR1 | tectonin beta-propeller repeat containing 1 | -16.8108 |
| DLEC1 | deleted in lung and esophageal cancer 1 | -16.4647 |
| STK16 | serine/threonine kinase 16 | -16.267 |
| C19ORF54 | chromosome 19 open reading frame 54 | -16.244 |
| FMO1 | flavin containing monooxygenase 1 | -15.8916 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -15.7283 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -15.438 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 | -14.8041 |
| FANCD2OS | FANCD2 opposite strand | -14.5221 |
| POLR3H | polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) | -14.5037 |
| TRIM59 | tripartite motif containing 59 | -14.3058 |
| SAMD11 | sterile alpha motif domain containing 11 | -13.7881 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | -13.5742 |
| IGF2R | insulin-like growth factor 2 receptor | -13.5706 |
| TCP1 | t-complex 1 | -13.5422 |
| FAM134C | family with sequence similarity 134, member C | -13.4847 |
| FANCI | Fanconi anemia, complementation group I | -13.2476 |
| GPS2 | G protein pathway suppressor 2 | -13.0985 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -12.9131 |
| KRI1 | KRI1 homolog (S. cerevisiae) | -12.8713 |
| INTS8 | integrator complex subunit 8 | -12.8376 |
| PMEL | premelanosome protein | -12.6829 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -12.6431 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | -12.6024 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 | -12.1642 |
| LRRC59 | leucine rich repeat containing 59 | -12.0006 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -11.7095 |
| MYL5 | myosin, light chain 5, regulatory | -11.4325 |
| TSPAN31 | tetraspanin 31 | -11.4157 |
| ADCY3 | adenylate cyclase 3 | -11.3676 |
| TUBB6 | tubulin, beta 6 class V | -11.2461 |
| WDR33 | WD repeat domain 33 | -11.1427 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | -10.9605 |
| LCTL | lactase-like | -10.8237 |
| PDGFRL | platelet-derived growth factor receptor-like | -10.8187 |
| ENO3 | enolase 3 (beta, muscle) | -10.7845 |
| METTL5 | methyltransferase like 5 | -10.7677 |
| TFIP11 | tuftelin interacting protein 11 | -10.7626 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -10.6929 |
| FAM149B1 | family with sequence similarity 149, member B1 | -10.6468 |
| DNASE1 | deoxyribonuclease I | -10.6125 |
| CCNK | cyclin K | -10.6064 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 | -10.5225 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) | -10.433 |
| PSMC3IP | PSMC3 interacting protein | -10.3858 |
| SMCR8 | Smith-Magenis syndrome chromosome region, candidate 8 | -10.2774 |
| MCMDC2 | minichromosome maintenance domain containing 2 | -10.1664 |
| NME7 | NME/NM23 family member 7 | -10.0254 |
| MROH1 | maestro heat-like repeat family member 1 | -9.88249 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | -9.72681 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -9.71384 |
| TOX4 | TOX high mobility group box family member 4 | -9.61481 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -9.60161 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -9.47124 |
| LHFPL5 | lipoma HMGIC fusion partner-like 5 | -9.40158 |
| CENPP | centromere protein P | -9.2977 |
| RNF24 | ring finger protein 24 | -9.25584 |
| C19ORF44 | chromosome 19 open reading frame 44 | -9.21705 |
| PMCH | pro-melanin-concentrating hormone | -9.05187 |
