Perturb_11407_KD_HNRNPM_SRP143499 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting HNRNPM in LNCaP cell line (Study accession: SRP143499) (PerturbAtlas)
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Genes

200 genes differentially expressed following the Perturb_11407_KD_HNRNPM_SRP143499 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
DSG1 desmoglein 1 20.0
C18ORF8 chromosome 18 open reading frame 8 20.0
MIA3 melanoma inhibitory activity family, member 3 20.0
UBE2N ubiquitin-conjugating enzyme E2N 20.0
COLCA2 colorectal cancer associated 2 20.0
C7ORF49 chromosome 7 open reading frame 49 20.0
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 20.0
EMG1 EMG1 N1-specific pseudouridine methyltransferase 20.0
NPB neuropeptide B 20.0
ACSS3 acyl-CoA synthetase short-chain family member 3 20.0
COL5A1 collagen, type V, alpha 1 19.699
SYT4 synaptotagmin IV 16.8592
C12ORF73 chromosome 12 open reading frame 73 15.8578
CDH4 cadherin 4, type 1, R-cadherin (retinal) 15.4248
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 15.2728
CRLF1 cytokine receptor-like factor 1 15.0824
TCP11L1 t-complex 11, testis-specific-like 1 14.9748
IDUA iduronidase, alpha-L- 14.3092
TMEM63B transmembrane protein 63B 14.3003
CENPP centromere protein P 13.468
SIAH1 siah E3 ubiquitin protein ligase 1 13.1425
TBC1D16 TBC1 domain family, member 16 13.0035
MTERF4 mitochondrial transcription termination factor 4 12.6059
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 12.3823
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 12.2722
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 12.2005
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 12.1186
C5ORF45 chromosome 5 open reading frame 45 11.8993
ANKRD61 ankyrin repeat domain 61 11.4243
SH3D19 SH3 domain containing 19 10.9957
TBPL1 TBP-like 1 10.8361
PRH1 proline-rich protein HaeIII subfamily 1 10.4829
CLVS1 clavesin 1 10.4829
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 10.4046
PTRH2 peptidyl-tRNA hydrolase 2 10.1576
ACSBG1 acyl-CoA synthetase bubblegum family member 1 9.92037
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 9.89275
CXORF36 chromosome X open reading frame 36 9.83907
CSNK1D casein kinase 1, delta 9.83491
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 9.51845
OVCH2 ovochymase 2 (gene/pseudogene) 9.51845
BEST1 bestrophin 1 9.28855
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 9.28498
FAR2 fatty acyl CoA reductase 2 9.16737
GLIPR1 GLI pathogenesis-related 1 8.88705
TCP1 t-complex 1 8.84664
ATPIF1 ATPase inhibitory factor 1 8.6014
SNX22 sorting nexin 22 8.38382
FAM63A family with sequence similarity 63, member A 8.36569
STAG3 stromal antigen 3 8.06559
SPATA21 spermatogenesis associated 21 8.05672
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 8.05581
DCAF17 DDB1 and CUL4 associated factor 17 8.01475
GPRC5B G protein-coupled receptor, class C, group 5, member B 8.00451
ATG7 autophagy related 7 7.84679
SFT2D3 SFT2 domain containing 3 7.5183
SRR serine racemase 7.3523
GLP1R glucagon-like peptide 1 receptor 7.26776
C1ORF167 chromosome 1 open reading frame 167 7.10689
DOPEY1 dopey family member 1 6.99625
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 6.88934
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 6.69478
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 6.67327
RAB6C RAB6C, member RAS oncogene family 6.66471
NUP88 nucleoporin 88kDa 6.39743
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 6.32622
MSH3 mutS homolog 3 6.10797
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 6.08931
TNPO1 transportin 1 5.88131
SPC24 SPC24, NDC80 kinetochore complex component 5.8586
TCHP trichoplein, keratin filament binding 5.72112
ANAPC11 anaphase promoting complex subunit 11 5.6321
ARHGAP5 Rho GTPase activating protein 5 5.6153
FAM69A family with sequence similarity 69, member A 5.53589
POLQ polymerase (DNA directed), theta 5.49851
GLRX5 glutaredoxin 5 5.49373
NRDE2 NRDE-2, necessary for RNA interference, domain containing 5.46253
IQCK IQ motif containing K 5.436
FCHSD1 FCH and double SH3 domains 1 5.32697
CNTD1 cyclin N-terminal domain containing 1 5.30557
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 5.2868
PLTP phospholipid transfer protein 5.16699
FADS1 fatty acid desaturase 1 5.15061
VWA1 von Willebrand factor A domain containing 1 5.14861
RNPEP arginyl aminopeptidase (aminopeptidase B) 5.13054
KIF9 kinesin family member 9 5.10877
CIRBP cold inducible RNA binding protein 5.09458
MAST2 microtubule associated serine/threonine kinase 2 5.04866
AMD1 adenosylmethionine decarboxylase 1 4.99916
METTL5 methyltransferase like 5 4.93846
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 4.93721
MROH1 maestro heat-like repeat family member 1 4.87763
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 4.84525
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 4.80392
SLC7A6OS solute carrier family 7, member 6 opposite strand 4.79981
LYRM5 LYR motif containing 5 4.76977
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 4.76711
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 4.72803
WBSCR16 Williams-Beuren syndrome chromosome region 16 4.70057
FASN fatty acid synthase 4.62314

decreased expression

Symbol Name Standardized Value
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -20.0
PAQR3 progestin and adipoQ receptor family member III -20.0
ZNF135 zinc finger protein 135 -20.0
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -20.0
THBS1 thrombospondin 1 -20.0
SPATA1 spermatogenesis associated 1 -20.0
WDR33 WD repeat domain 33 -20.0
ASB14 ankyrin repeat and SOCS box containing 14 -20.0
USP3 ubiquitin specific peptidase 3 -20.0
CFAP126 cilia and flagella associated protein 126 -20.0
WIPI1 WD repeat domain, phosphoinositide interacting 1 -20.0
ZNF337 zinc finger protein 337 -19.0969
ITGB1BP1 integrin beta 1 binding protein 1 -19.0969
FKRP fukutin related protein -18.6778
H2AFY H2A histone family, member Y -17.2873
BOLA1 bolA family member 1 -16.7577
GLRX2 glutaredoxin 2 -16.572
SIK2 salt-inducible kinase 2 -15.9544
SCLT1 sodium channel and clathrin linker 1 -13.8554
PTGFR prostaglandin F receptor (FP) -13.4689
NR2C2 nuclear receptor subfamily 2, group C, member 2 -13.1397
BAG2 BCL2-associated athanogene 2 -12.9548
CCDC159 coiled-coil domain containing 159 -12.0894
LOC338667 V-set and immunoglobulin domain-containing protein 10-like -11.8993
RBM4B RNA binding motif protein 4B -11.7689
PLXDC1 plexin domain containing 1 -11.126
ATP4B ATPase, H+/K+ exchanging, beta polypeptide -11.1212
ANKH ANKH inorganic pyrophosphate transport regulator -11.0053
MXRA8 matrix-remodelling associated 8 -10.9136
AMDHD2 amidohydrolase domain containing 2 -10.7969
ZNF562 zinc finger protein 562 -10.3317
ICA1 islet cell autoantigen 1, 69kDa -10.1474
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -9.99533
HNRNPM heterogeneous nuclear ribonucleoprotein M -9.79762
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -9.60906
SCAI suppressor of cancer cell invasion -9.41397
FMNL3 formin-like 3 -9.23748
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -9.16164
HIST1H1E histone cluster 1, H1e -9.08142
DIS3L DIS3 like exosome 3'-5' exoribonuclease -9.05206
STK17A serine/threonine kinase 17a -8.90443
SIAE sialic acid acetylesterase -8.76527
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -8.74218
METRN meteorin, glial cell differentiation regulator -8.68457
ERI2 ERI1 exoribonuclease family member 2 -8.63549
CRYZ crystallin, zeta (quinone reductase) -8.38382
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -8.35727
ZBTB45 zinc finger and BTB domain containing 45 -8.18481
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase -8.17975
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 -8.09408
RECQL RecQ helicase-like -8.00784
LRRC8E leucine rich repeat containing 8 family, member E -8.00784
ZC3H14 zinc finger CCCH-type containing 14 -8.00575
LDLRAD2 low density lipoprotein receptor class A domain containing 2 -7.98799
ALX3 ALX homeobox 3 -7.94689
MZF1 myeloid zinc finger 1 -7.64993
COX11 COX11 cytochrome c oxidase copper chaperone -7.64316
AVIL advillin -7.62066
FAM184B family with sequence similarity 184, member B -7.60612
OXCT1 3-oxoacid CoA transferase 1 -7.51709
FBXO25 F-box protein 25 -7.48256
SLC26A1 solute carrier family 26 (anion exchanger), member 1 -7.33862
TMEM8B transmembrane protein 8B -7.21523
MXRA7 matrix-remodelling associated 7 -7.06744
PEX10 peroxisomal biogenesis factor 10 -6.72547
COL10A1 collagen, type X, alpha 1 -6.68328
RAB40A RAB40A, member RAS oncogene family -6.58189
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -6.4669
TIGD7 tigger transposable element derived 7 -6.40807
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -6.36539
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A -6.31844
HIST1H1C histone cluster 1, H1c -6.30475
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) -6.22536
TNNI1 troponin I type 1 (skeletal, slow) -6.09136
CEMIP cell migration inducing protein, hyaluronan binding -6.03157
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -6.00247
GCC2 GRIP and coiled-coil domain containing 2 -5.99742
ACKR4 atypical chemokine receptor 4 -5.96934
TRIM7 tripartite motif containing 7 -5.85232
VASH1 vasohibin 1 -5.77787
SEPT2 septin 2 -5.72214
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -5.63162
PELI3 pellino E3 ubiquitin protein ligase family member 3 -5.59924
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -5.3231
RNF24 ring finger protein 24 -5.30575
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -5.07283
JTB jumping translocation breakpoint -5.05473
GARS glycyl-tRNA synthetase -5.0417
C12ORF76 chromosome 12 open reading frame 76 -5.0191
ZNF717 zinc finger protein 717 -4.94617
ERAP1 endoplasmic reticulum aminopeptidase 1 -4.92806
POLR1B polymerase (RNA) I polypeptide B, 128kDa -4.89877
SLC46A1 solute carrier family 46 (folate transporter), member 1 -4.89663
ASPG asparaginase -4.87508
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase -4.80118
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -4.77241
PPP1R16A protein phosphatase 1, regulatory subunit 16A -4.7404
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -4.72915
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -4.69784
LTB4R2 leukotriene B4 receptor 2 -4.69496