| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting CD95L in LNCaP cell line (Study accession: SRP302700) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_11419_KD_CD95L_SRP302700 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM184C | transmembrane protein 184C | 20.0 |
| KDM6B | lysine (K)-specific demethylase 6B | 20.0 |
| WNK2 | WNK lysine deficient protein kinase 2 | 20.0 |
| MED16 | mediator complex subunit 16 | 20.0 |
| RNF44 | ring finger protein 44 | 20.0 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | 20.0 |
| NCOR2 | nuclear receptor corepressor 2 | 20.0 |
| MCM2 | minichromosome maintenance complex component 2 | 20.0 |
| USF2 | upstream transcription factor 2, c-fos interacting | 20.0 |
| SOX12 | SRY (sex determining region Y)-box 12 | 20.0 |
| ZDHHC5 | zinc finger, DHHC-type containing 5 | 20.0 |
| MIDN | midnolin | 20.0 |
| RPUSD1 | RNA pseudouridylate synthase domain containing 1 | 20.0 |
| ALCAM | activated leukocyte cell adhesion molecule | 20.0 |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) | 20.0 |
| SET | SET nuclear proto-oncogene | 20.0 |
| MARVELD1 | MARVEL domain containing 1 | 20.0 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 20.0 |
| DNAAF5 | dynein, axonemal, assembly factor 5 | 20.0 |
| FAM155B | family with sequence similarity 155, member B | 20.0 |
| REPIN1 | replication initiator 1 | 20.0 |
| FN1 | fibronectin 1 | 20.0 |
| RNF4 | ring finger protein 4 | 20.0 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 20.0 |
| JUND | jun D proto-oncogene | 20.0 |
| POM121C | POM121 transmembrane nucleoporin C | 20.0 |
| ARHGAP1 | Rho GTPase activating protein 1 | 20.0 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 20.0 |
| ITFG3 | integrin alpha FG-GAP repeat containing 3 | 20.0 |
| MORF4L1 | mortality factor 4 like 1 | 20.0 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 20.0 |
| RNF187 | ring finger protein 187 | 20.0 |
| ABR | active BCR-related | 20.0 |
| TAPBP | TAP binding protein (tapasin) | 20.0 |
| NAT8L | N-acetyltransferase 8-like (GCN5-related, putative) | 20.0 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 20.0 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 20.0 |
| DAP | death-associated protein | 20.0 |
| BCL9L | B-cell CLL/lymphoma 9-like | 20.0 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 20.0 |
| ENAH | enabled homolog (Drosophila) | 20.0 |
| MED22 | mediator complex subunit 22 | 20.0 |
| STK40 | serine/threonine kinase 40 | 20.0 |
| SRM | spermidine synthase | 20.0 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 | 20.0 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 20.0 |
| SZRD1 | SUZ RNA binding domain containing 1 | 20.0 |
| CAPN15 | calpain 15 | 20.0 |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 | 20.0 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 20.0 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 20.0 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 20.0 |
| MAP4 | microtubule-associated protein 4 | 20.0 |
| TOM1L2 | target of myb1-like 2 (chicken) | 20.0 |
| ZNF598 | zinc finger protein 598 | 20.0 |
| WNT7B | wingless-type MMTV integration site family, member 7B | 20.0 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 20.0 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 20.0 |
| PROSER1 | proline and serine rich 1 | 20.0 |
| CBX6 | chromobox homolog 6 | 20.0 |
| CKAP5 | cytoskeleton associated protein 5 | 20.0 |
| ANKRD52 | ankyrin repeat domain 52 | 20.0 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 20.0 |
| FOXP4 | forkhead box P4 | 20.0 |
| MAP1B | microtubule-associated protein 1B | 20.0 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 20.0 |
| KLHDC3 | kelch domain containing 3 | 20.0 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 20.0 |
| NOTCH1 | notch 1 | 20.0 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 20.0 |
| PRAC1 | prostate cancer susceptibility candidate 1 | 20.0 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 20.0 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 20.0 |
| USP10 | ubiquitin specific peptidase 10 | 20.0 |
| NIPAL3 | NIPA-like domain containing 3 | 20.0 |
| NUP210 | nucleoporin 210kDa | 20.0 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 20.0 |
| CPTP | ceramide-1-phosphate transfer protein | 20.0 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 20.0 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | 20.0 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 20.0 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 20.0 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 20.0 |
| RBM15B | RNA binding motif protein 15B | 20.0 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 20.0 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 20.0 |
| DSEL | dermatan sulfate epimerase-like | 20.0 |
| LONP1 | lon peptidase 1, mitochondrial | 20.0 |
| NONO | non-POU domain containing, octamer-binding | 20.0 |
| POM121 | POM121 transmembrane nucleoporin | 20.0 |
| GATAD2A | GATA zinc finger domain containing 2A | 20.0 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | 20.0 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 20.0 |
| H2AFX | H2A histone family, member X | 20.0 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 20.0 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin | 20.0 |
| FAM83F | family with sequence similarity 83, member F | 20.0 |
| ABHD2 | abhydrolase domain containing 2 | 20.0 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 20.0 |
| NCS1 | neuronal calcium sensor 1 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTSSA | serine palmitoyltransferase, small subunit A | -20.0 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | -20.0 |
| TEF | thyrotrophic embryonic factor | -20.0 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | -20.0 |
| GSKIP | GSK3B interacting protein | -20.0 |
| LIMA1 | LIM domain and actin binding 1 | -20.0 |
| RAB12 | RAB12, member RAS oncogene family | -20.0 |
| TMTC4 | transmembrane and tetratricopeptide repeat containing 4 | -20.0 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -20.0 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -20.0 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -20.0 |
| FOPNL | FGFR1OP N-terminal like | -20.0 |
| ARMC1 | armadillo repeat containing 1 | -20.0 |
| TSEN15 | TSEN15 tRNA splicing endonuclease subunit | -20.0 |
| FNDC3A | fibronectin type III domain containing 3A | -20.0 |
| STK38 | serine/threonine kinase 38 | -20.0 |
| KLHDC8B | kelch domain containing 8B | -20.0 |
| TUFT1 | tuftelin 1 | -20.0 |
| SEC24A | SEC24 family member A | -20.0 |
| JKAMP | JNK1/MAPK8-associated membrane protein | -20.0 |
| KLHL28 | kelch-like family member 28 | -20.0 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -20.0 |
| HIST1H2BG | histone cluster 1, H2bg | -20.0 |
| VAMP7 | vesicle-associated membrane protein 7 | -20.0 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 | -20.0 |
| SORT1 | sortilin 1 | -20.0 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 | -20.0 |
| ZNF350 | zinc finger protein 350 | -20.0 |
| XXYLT1 | xyloside xylosyltransferase 1 | -20.0 |
| SCAMP5 | secretory carrier membrane protein 5 | -20.0 |
| TMEM43 | transmembrane protein 43 | -20.0 |
| SNAPIN | SNAP-associated protein | -20.0 |
| USP46 | ubiquitin specific peptidase 46 | -20.0 |
| C9ORF41 | chromosome 9 open reading frame 41 | -20.0 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -20.0 |
| ACER2 | alkaline ceramidase 2 | -20.0 |
| FRK | fyn-related Src family tyrosine kinase | -20.0 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | -20.0 |
| FAM217B | family with sequence similarity 217, member B | -20.0 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) | -20.0 |
| E2F3 | E2F transcription factor 3 | -20.0 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -20.0 |
| WDR37 | WD repeat domain 37 | -20.0 |
| RAB11FIP4 | RAB11 family interacting protein 4 (class II) | -20.0 |
| STXBP4 | syntaxin binding protein 4 | -20.0 |
| TMEM2 | transmembrane protein 2 | -20.0 |
| CCNT2 | cyclin T2 | -20.0 |
| DESI1 | desumoylating isopeptidase 1 | -20.0 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -20.0 |
| BTBD7 | BTB (POZ) domain containing 7 | -20.0 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -20.0 |
| CEL | carboxyl ester lipase | -20.0 |
| ZYG11B | zyg-11 family member B, cell cycle regulator | -20.0 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -20.0 |
| CAMLG | calcium modulating ligand | -20.0 |
| FBXO45 | F-box protein 45 | -20.0 |
| LIN7C | lin-7 homolog C (C. elegans) | -20.0 |
| SNW1 | SNW domain containing 1 | -20.0 |
| CLDND1 | claudin domain containing 1 | -20.0 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | -20.0 |
| KLHL42 | kelch-like family member 42 | -20.0 |
| CASD1 | CAS1 domain containing 1 | -20.0 |
| IGSF3 | immunoglobulin superfamily, member 3 | -20.0 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -20.0 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -20.0 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -20.0 |
| KLHL15 | kelch-like family member 15 | -20.0 |
| PCID2 | PCI domain containing 2 | -20.0 |
| PFN2 | profilin 2 | -20.0 |
| RYK | receptor-like tyrosine kinase | -20.0 |
| CHIC1 | cysteine-rich hydrophobic domain 1 | -20.0 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | -20.0 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 | -20.0 |
| USP12 | ubiquitin specific peptidase 12 | -20.0 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | -20.0 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | -20.0 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -20.0 |
| FAM35A | family with sequence similarity 35, member A | -20.0 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -20.0 |
| MXD1 | MAX dimerization protein 1 | -20.0 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -20.0 |
| CBR1 | carbonyl reductase 1 | -20.0 |
| TRMT10C | tRNA methyltransferase 10 homolog C (S. cerevisiae) | -20.0 |
| KLHL20 | kelch-like family member 20 | -20.0 |
| NLRP6 | NLR family, pyrin domain containing 6 | -20.0 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -20.0 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | -20.0 |
| TBCC | tubulin folding cofactor C | -20.0 |
| ABHD3 | abhydrolase domain containing 3 | -20.0 |
| MXI1 | MAX interactor 1, dimerization protein | -20.0 |
| VANGL1 | VANGL planar cell polarity protein 1 | -20.0 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -20.0 |
| KIAA0513 | KIAA0513 | -20.0 |
| NEK7 | NIMA-related kinase 7 | -20.0 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -20.0 |
| MPZL3 | myelin protein zero-like 3 | -20.0 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | -20.0 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -20.0 |
| TRIM23 | tripartite motif containing 23 | -20.0 |
| ANKRD46 | ankyrin repeat domain 46 | -20.0 |