| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting RUNX1 in lymphoblast(HL-60) cell line (Study accession: SRP199099) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_11930_KO_RUNX1_SRP199099 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 20.0 |
| C1ORF186 | chromosome 1 open reading frame 186 | 20.0 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | 20.0 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) | 20.0 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 19.3979 |
| TERT | telomerase reverse transcriptase | 19.0 |
| CD84 | CD84 molecule | 15.4527 |
| RAB7B | RAB7B, member RAS oncogene family | 15.029 |
| COL4A2 | collagen, type IV, alpha 2 | 14.6381 |
| AHNAK | AHNAK nucleoprotein | 14.5337 |
| NOG | noggin | 14.2301 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 13.8369 |
| ECE1 | endothelin converting enzyme 1 | 13.5013 |
| NRCAM | neuronal cell adhesion molecule | 13.2165 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | 13.0914 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 13.0697 |
| TFRC | transferrin receptor | 11.4139 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | 10.7884 |
| MARCKSL1 | MARCKS-like 1 | 10.4861 |
| FGFR1 | fibroblast growth factor receptor 1 | 10.1589 |
| GAL | galanin/GMAP prepropeptide | 10.0604 |
| CORIN | corin, serine peptidase | 10.0453 |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | 9.8295 |
| IRF5 | interferon regulatory factor 5 | 9.63264 |
| NPTX1 | neuronal pentraxin I | 9.59497 |
| TUBB4B | tubulin, beta 4B class IVb | 8.27338 |
| ANXA8 | annexin A8 | 7.88806 |
| PRTN3 | proteinase 3 | 7.67794 |
| VCP | valosin containing protein | 7.46207 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 7.33951 |
| STMN3 | stathmin-like 3 | 7.21938 |
| OAF | OAF homolog (Drosophila) | 7.1243 |
| SMAD3 | SMAD family member 3 | 6.67088 |
| CA8 | carbonic anhydrase VIII | 6.57767 |
| KITLG | KIT ligand | 6.56565 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 6.55742 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 6.19226 |
| EPHB2 | EPH receptor B2 | 6.07216 |
| PLCG1 | phospholipase C, gamma 1 | 5.96858 |
| ARHGAP23 | Rho GTPase activating protein 23 | 5.96721 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 5.7454 |
| TRIM24 | tripartite motif containing 24 | 5.65572 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 5.29005 |
| SCUBE1 | signal peptide, CUB domain, EGF-like 1 | 5.28303 |
| FOXN4 | forkhead box N4 | 5.04225 |
| CLC | Charcot-Leyden crystal galectin | 5.01906 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 | 4.84069 |
| ELANE | elastase, neutrophil expressed | 4.75187 |
| CDCA7 | cell division cycle associated 7 | 4.74149 |
| JUP | junction plakoglobin | 4.68787 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 4.66803 |
| PRDX1 | peroxiredoxin 1 | 4.63464 |
| GATA2 | GATA binding protein 2 | 4.56889 |
| NUP62 | nucleoporin 62kDa | 4.5539 |
| GRIP2 | glutamate receptor interacting protein 2 | 4.53828 |
| LY86 | lymphocyte antigen 86 | 4.52499 |
| RUNX2 | runt-related transcription factor 2 | 4.49278 |
| ARMC6 | armadillo repeat containing 6 | 4.44614 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 4.39681 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 4.32675 |
| CD320 | CD320 molecule | 4.25257 |
| SLC45A3 | solute carrier family 45, member 3 | 4.18444 |
| CCDC86 | coiled-coil domain containing 86 | 4.12341 |
| WDR77 | WD repeat domain 77 | 4.07448 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 3.94693 |
| PPP1R27 | protein phosphatase 1, regulatory subunit 27 | 3.93883 |
| NBPF9 | neuroblastoma breakpoint family, member 9 | 3.93341 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 3.90578 |
| FAM117A | family with sequence similarity 117, member A | 3.87298 |
| HSPB1 | heat shock 27kDa protein 1 | 3.87298 |
| GPR85 | G protein-coupled receptor 85 | 3.86663 |
| ARL4C | ADP-ribosylation factor-like 4C | 3.77699 |
| ANKRD33B | ankyrin repeat domain 33B | 3.77294 |
| ISOC2 | isochorismatase domain containing 2 | 3.77021 |
| GTF3C6 | general transcription factor IIIC, polypeptide 6, alpha 35kDa | 3.55494 |
| MSI2 | musashi RNA-binding protein 2 | 3.53859 |
| DMWD | dystrophia myotonica, WD repeat containing | 3.52326 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 3.51518 |
| CIRH1A | cirrhosis, autosomal recessive 1A (cirhin) | 3.40965 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 3.38397 |
| COPRS | coordinator of PRMT5, differentiation stimulator | 3.36022 |
| ODC1 | ornithine decarboxylase 1 | 3.36022 |
| SDC1 | syndecan 1 | 3.3539 |
| TMEM173 | transmembrane protein 173 | 3.33501 |
| GEMIN5 | gem (nuclear organelle) associated protein 5 | 3.32569 |
| FJX1 | four jointed box 1 (Drosophila) | 3.24563 |
| TFEC | transcription factor EC | 3.24375 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 3.21382 |
| P2RY8 | purinergic receptor P2Y, G-protein coupled, 8 | 3.21382 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 3.18428 |
| DMPK | dystrophia myotonica-protein kinase | 3.18019 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 3.17798 |
| TRMT61A | tRNA methyltransferase 61A | 3.17111 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 3.15276 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK | 3.14785 |
| UNG | uracil-DNA glycosylase | 3.14348 |
| EMILIN2 | elastin microfibril interfacer 2 | 3.14017 |
| SORD | sorbitol dehydrogenase | 3.12374 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 3.12239 |
| LPXN | leupaxin | 3.09147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCH1 | phospholipase C, eta 1 | -20.0 |
| KIF21B | kinesin family member 21B | -20.0 |
| ATF5 | activating transcription factor 5 | -20.0 |
| KRT81 | keratin 81, type II | -20.0 |
| ANXA3 | annexin A3 | -20.0 |
| FCRLA | Fc receptor-like A | -20.0 |
| RETN | resistin | -20.0 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -18.9208 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | -18.4318 |
| SYTL1 | synaptotagmin-like 1 | -17.6498 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -16.9674 |
| PSAT1 | phosphoserine aminotransferase 1 | -16.408 |
| MCEMP1 | mast cell-expressed membrane protein 1 | -16.1304 |
| STC2 | stanniocalcin 2 | -15.774 |
| GARS | glycyl-tRNA synthetase | -14.2301 |
| UNC5C | unc-5 homolog C (C. elegans) | -14.2301 |
| GPR84 | G protein-coupled receptor 84 | -13.6855 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -13.4761 |
| ALOX5 | arachidonate 5-lipoxygenase | -13.0697 |
| RIN2 | Ras and Rab interactor 2 | -13.0279 |
| ADM2 | adrenomedullin 2 | -12.9652 |
| S100P | S100 calcium binding protein P | -12.1033 |
| AARS | alanyl-tRNA synthetase | -11.9306 |
| CTSG | cathepsin G | -11.6662 |
| C10ORF54 | chromosome 10 open reading frame 54 | -11.5653 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -11.4139 |
| SPTB | spectrin, beta, erythrocytic | -10.9051 |
| UNC5B | unc-5 homolog B (C. elegans) | -10.7884 |
| C11ORF21 | chromosome 11 open reading frame 21 | -10.228 |
| SLFN5 | schlafen family member 5 | -10.1702 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -10.007 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | -9.94322 |
| C5AR1 | complement component 5a receptor 1 | -9.7007 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -9.55286 |
| ASS1 | argininosuccinate synthase 1 | -9.45761 |
| FAM134B | family with sequence similarity 134, member B | -9.43088 |
| SH3BP2 | SH3-domain binding protein 2 | -9.23119 |
| ADGRG3 | adhesion G protein-coupled receptor G3 | -9.13416 |
| TMOD2 | tropomodulin 2 (neuronal) | -8.82255 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -8.82255 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -8.80077 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -8.70997 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -8.70319 |
| PHGDH | phosphoglycerate dehydrogenase | -8.67307 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | -8.65631 |
| MRC2 | mannose receptor, C type 2 | -8.39693 |
| WARS | tryptophanyl-tRNA synthetase | -8.3642 |
| GTPBP2 | GTP binding protein 2 | -8.20969 |
| ATF3 | activating transcription factor 3 | -8.11147 |
| MPZ | myelin protein zero | -8.11147 |
| KDM6B | lysine (K)-specific demethylase 6B | -8.0239 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -7.95351 |
| SESN2 | sestrin 2 | -7.89509 |
| TREML2 | triggering receptor expressed on myeloid cells-like 2 | -7.8354 |
| ALPK1 | alpha-kinase 1 | -7.80498 |
| CCPG1 | cell cycle progression 1 | -7.80498 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -7.7427 |
| ATF4 | activating transcription factor 4 | -7.69205 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -7.53223 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) | -7.47435 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -7.43298 |
| TRIB3 | tribbles pseudokinase 3 | -7.43174 |
| SLC22A15 | solute carrier family 22, member 15 | -7.22916 |
| CARS | cysteinyl-tRNA synthetase | -7.20762 |
| TSPAN14 | tetraspanin 14 | -7.11079 |
| JAG1 | jagged 1 | -7.10184 |
| CTH | cystathionine gamma-lyase | -7.03881 |
| ENO2 | enolase 2 (gamma, neuronal) | -7.03436 |
| ANK2 | ankyrin 2, neuronal | -7.01686 |
| TBC1D10C | TBC1 domain family, member 10C | -6.89663 |
| BMF | Bcl2 modifying factor | -6.89556 |
| VLDLR | very low density lipoprotein receptor | -6.89066 |
| RRAGD | Ras-related GTP binding D | -6.85456 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase | -6.81641 |
| TGM5 | transglutaminase 5 | -6.69014 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -6.57767 |
| OSBPL6 | oxysterol binding protein-like 6 | -6.48194 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -6.42171 |
| TES | testin LIM domain protein | -6.28079 |
| DGKA | diacylglycerol kinase, alpha 80kDa | -6.21424 |
| HOXB9 | homeobox B9 | -6.19226 |
| CCND3 | cyclin D3 | -6.17113 |
| HLA-C | major histocompatibility complex, class I, C | -6.13357 |
| TCEA2 | transcription elongation factor A (SII), 2 | -6.07101 |
| AIG1 | androgen-induced 1 | -6.02743 |
| NXF3 | nuclear RNA export factor 3 | -5.99012 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -5.97485 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -5.97034 |
| OSCAR | osteoclast associated, immunoglobulin-like receptor | -5.95535 |
| CLIC4 | chloride intracellular channel 4 | -5.94145 |
| MARS | methionyl-tRNA synthetase | -5.92441 |
| PRRT4 | proline-rich transmembrane protein 4 | -5.89493 |
| CLEC5A | C-type lectin domain family 5, member A | -5.89385 |
| HSH2D | hematopoietic SH2 domain containing | -5.82093 |
| THEMIS2 | thymocyte selection associated family member 2 | -5.76554 |
| FILIP1L | filamin A interacting protein 1-like | -5.74759 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -5.737 |
| PCYOX1L | prenylcysteine oxidase 1 like | -5.737 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -5.72879 |
| LONP1 | lon peptidase 1, mitochondrial | -5.56722 |
