| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | OE perturbation targeting linc00520 in MCF10A(breast epithelial) cell line (Study accession: SRP083129) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_12187_OE_linc00520_SRP083129 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 20.0 |
| CNTN1 | contactin 1 | 20.0 |
| UBE2T | ubiquitin-conjugating enzyme E2T | 20.0 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 20.0 |
| TPM3 | tropomyosin 3 | 20.0 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 20.0 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 20.0 |
| CDC20 | cell division cycle 20 | 20.0 |
| CACYBP | calcyclin binding protein | 20.0 |
| PLXNA2 | plexin A2 | 20.0 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 20.0 |
| KIF14 | kinesin family member 14 | 20.0 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 20.0 |
| LAMC2 | laminin, gamma 2 | 20.0 |
| CLSPN | claspin | 20.0 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 20.0 |
| RGS2 | regulator of G-protein signaling 2 | 20.0 |
| CTPS1 | CTP synthase 1 | 19.5229 |
| CLCA2 | chloride channel accessory 2 | 19.5229 |
| STIL | SCL/TAL1 interrupting locus | 19.5229 |
| USP1 | ubiquitin specific peptidase 1 | 18.8539 |
| TCEB3 | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 18.3468 |
| NEK2 | NIMA-related kinase 2 | 17.2967 |
| CDC7 | cell division cycle 7 | 16.4226 |
| ORC1 | origin recognition complex, subunit 1 | 16.3556 |
| LAD1 | ladinin 1 | 15.6952 |
| DEPDC1 | DEP domain containing 1 | 15.5492 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 15.4004 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 14.9354 |
| NDC1 | NDC1 transmembrane nucleoporin | 14.4867 |
| CDCA8 | cell division cycle associated 8 | 14.4516 |
| KIF2C | kinesin family member 2C | 14.3398 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 13.9594 |
| STMN1 | stathmin 1 | 13.6317 |
| EBNA1BP2 | EBNA1 binding protein 2 | 13.4471 |
| SH2D2A | SH2 domain containing 2A | 13.3406 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 13.0363 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 13.0347 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 12.5311 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 12.4844 |
| FOXE1 | forkhead box E1 | 11.9506 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 11.9134 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 | 11.9036 |
| SFN | stratifin | 11.4035 |
| ZMPSTE24 | zinc metallopeptidase STE24 | 11.2905 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 11.1275 |
| IPO9 | importin 9 | 11.032 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 11.03 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 10.9872 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 10.7436 |
| NUDC | nudC nuclear distribution protein | 10.5447 |
| PRSS8 | protease, serine, 8 | 10.3336 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 10.2022 |
| C1ORF116 | chromosome 1 open reading frame 116 | 9.84786 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 9.70015 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 9.37067 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 9.19476 |
| C1ORF112 | chromosome 1 open reading frame 112 | 9.17443 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 9.09154 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 8.82844 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 8.7931 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 8.72725 |
| RPA2 | replication protein A2, 32kDa | 8.49397 |
| SRM | spermidine synthase | 8.37061 |
| SOAT1 | sterol O-acyltransferase 1 | 8.30659 |
| VANGL1 | VANGL planar cell polarity protein 1 | 8.06479 |
| AUNIP | aurora kinase A and ninein interacting protein | 7.99387 |
| CENPL | centromere protein L | 7.98821 |
| GPATCH4 | G patch domain containing 4 | 7.95159 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | 7.94416 |
| METTL13 | methyltransferase like 13 | 7.75534 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 7.65538 |
| DDX20 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 7.56 |
| E2F2 | E2F transcription factor 2 | 7.54197 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 7.39666 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | 7.30401 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | 7.24916 |
| UCK2 | uridine-cytidine kinase 2 | 7.24435 |
| CCDC18 | coiled-coil domain containing 18 | 7.19847 |
| NAV1 | neuron navigator 1 | 7.06006 |
| ATAD3A | ATPase family, AAA domain containing 3A | 7.05987 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 6.92771 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 6.84073 |
| PRRC2C | proline-rich coiled-coil 2C | 6.77917 |
| WDR77 | WD repeat domain 77 | 6.7483 |
| GJA5 | gap junction protein, alpha 5, 40kDa | 6.43353 |
| CCNA2 | cyclin A2 | 6.42807 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 6.36902 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | 6.36533 |
| FAM72B | family with sequence similarity 72, member B | 6.35372 |
| SASS6 | spindle assembly 6 homolog (C. elegans) | 6.31565 |
| MAP7D1 | MAP7 domain containing 1 | 6.31179 |
| RPE65 | retinal pigment epithelium-specific protein 65kDa | 6.26234 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 6.15065 |
| TOR3A | torsin family 3, member A | 5.96598 |
| TMEM201 | transmembrane protein 201 | 5.96195 |
| ATAD3B | ATPase family, AAA domain containing 3B | 5.87083 |
| LAMB3 | laminin, beta 3 | 5.84551 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 5.62418 |
| ILF2 | interleukin enhancer binding factor 2 | 5.59398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -20.0 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -20.0 |
| EFNA1 | ephrin-A1 | -20.0 |
| IL6R | interleukin 6 receptor | -20.0 |
| S100A9 | S100 calcium binding protein A9 | -20.0 |
| S100A6 | S100 calcium binding protein A6 | -20.0 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) | -20.0 |
| ITGA10 | integrin, alpha 10 | -20.0 |
| ETNK2 | ethanolamine kinase 2 | -20.0 |
| SORT1 | sortilin 1 | -20.0 |
| LAPTM5 | lysosomal protein transmembrane 5 | -20.0 |
| GLUL | glutamate-ammonia ligase | -20.0 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -19.699 |
| S100A14 | S100 calcium binding protein A14 | -19.0 |
| S100A4 | S100 calcium binding protein A4 | -18.7959 |
| MFSD2A | major facilitator superfamily domain containing 2A | -18.6576 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | -16.9108 |
| S100A8 | S100 calcium binding protein A8 | -16.2574 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | -15.5444 |
| CYP4X1 | cytochrome P450, family 4, subfamily X, polypeptide 1 | -15.4493 |
| TXNIP | thioredoxin interacting protein | -14.8732 |
| PAQR6 | progestin and adipoQ receptor family member VI | -14.6371 |
| KIAA1522 | KIAA1522 | -14.5888 |
| RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | -14.4516 |
| SYTL1 | synaptotagmin-like 1 | -14.3051 |
| MR1 | major histocompatibility complex, class I-related | -13.4515 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -13.1692 |
| SELENBP1 | selenium binding protein 1 | -12.395 |
| CCNL2 | cyclin L2 | -12.0295 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -11.5216 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -11.2597 |
| RORC | RAR-related orphan receptor C | -9.85623 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | -9.38626 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -9.12227 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -8.82426 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -8.57411 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -8.47464 |
| IRF6 | interferon regulatory factor 6 | -8.40066 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | -8.23326 |
| RPL5 | ribosomal protein L5 | -8.20049 |
| SLC44A5 | solute carrier family 44, member 5 | -8.19758 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -8.00639 |
| RPL11 | ribosomal protein L11 | -7.97537 |
| CFH | complement factor H | -7.85668 |
| MTFR1L | mitochondrial fission regulator 1-like | -7.84542 |
| MUC1 | mucin 1, cell surface associated | -7.75879 |
| RSRP1 | arginine/serine-rich protein 1 | -7.67368 |
| TGFBR3 | transforming growth factor, beta receptor III | -7.32158 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -7.27664 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -7.12838 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -7.08289 |
| FNBP1L | formin binding protein 1-like | -7.04958 |
| SLC35E2B | solute carrier family 35, member E2B | -7.01818 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -6.99052 |
| GOLT1A | golgi transport 1A | -6.55318 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -6.55318 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 | -6.52778 |
| HIST2H2BE | histone cluster 2, H2be | -6.489 |
| RPS8 | ribosomal protein S8 | -6.26234 |
| CDK18 | cyclin-dependent kinase 18 | -6.17226 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -6.05523 |
| RPS27 | ribosomal protein S27 | -5.96598 |
| LEPR | leptin receptor | -5.96249 |
| FAM63A | family with sequence similarity 63, member A | -5.71122 |
| KIAA0319L | KIAA0319-like | -5.71122 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 | -5.4669 |
| C1ORF43 | chromosome 1 open reading frame 43 | -5.34688 |
| PHGDH | phosphoglycerate dehydrogenase | -5.34511 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -5.31082 |
| SLC16A4 | solute carrier family 16, member 4 | -5.20104 |
| FBXO44 | F-box protein 44 | -5.07259 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -4.76679 |
| FBXO2 | F-box protein 2 | -4.7172 |
| UBE4B | ubiquitination factor E4B | -4.71407 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -4.7099 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | -4.61851 |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | -4.61663 |
| BTG2 | BTG family, member 2 | -4.56983 |
| SHISA4 | shisa family member 4 | -4.54246 |
| KDM4A | lysine (K)-specific demethylase 4A | -4.44247 |
| KDM5B | lysine (K)-specific demethylase 5B | -4.12465 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | -4.08223 |
| DRAM2 | DNA-damage regulated autophagy modulator 2 | -4.04581 |
| MEF2D | myocyte enhancer factor 2D | -4.03929 |
| CSF1 | colony stimulating factor 1 (macrophage) | -4.02706 |
| C1ORF21 | chromosome 1 open reading frame 21 | -4.02231 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -3.93924 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | -3.93104 |
| FAM189B | family with sequence similarity 189, member B | -3.83958 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | -3.70593 |
| SCNN1D | sodium channel, non voltage gated 1 delta subunit | -3.67411 |
| HSPG2 | heparan sulfate proteoglycan 2 | -3.6442 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | -3.50213 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 | -3.48629 |
| C1ORF210 | chromosome 1 open reading frame 210 | -3.47017 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | -3.32042 |
| TMEM125 | transmembrane protein 125 | -3.30022 |
| C1ORF106 | chromosome 1 open reading frame 106 | -3.29613 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | -3.28984 |
| EPB41 | erythrocyte membrane protein band 4.1 | -3.24495 |
