| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting EPRS in MCF7 TamR cells cell line (Study accession: SRP073504) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12217_KD_EPRS_SRP073504 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RFTN1 | raftlin, lipid raft linker 1 | 20.0 |
| CCDC154 | coiled-coil domain containing 154 | 20.0 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 20.0 |
| FAM65C | family with sequence similarity 65, member C | 20.0 |
| FAM3B | family with sequence similarity 3, member B | 20.0 |
| QPRT | quinolinate phosphoribosyltransferase | 20.0 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 20.0 |
| BAMBI | BMP and activin membrane-bound inhibitor | 20.0 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 | 20.0 |
| VIPR2 | vasoactive intestinal peptide receptor 2 | 20.0 |
| SELENBP1 | selenium binding protein 1 | 20.0 |
| LXN | latexin | 20.0 |
| MYO1G | myosin IG | 20.0 |
| CROT | carnitine O-octanoyltransferase | 20.0 |
| CERS4 | ceramide synthase 4 | 20.0 |
| SCN1B | sodium channel, voltage gated, type I beta subunit | 20.0 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 20.0 |
| ADCY5 | adenylate cyclase 5 | 20.0 |
| BDKRB2 | bradykinin receptor B2 | 20.0 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 20.0 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 20.0 |
| HPX | hemopexin | 20.0 |
| TMEM150C | transmembrane protein 150C | 18.7959 |
| ATP13A5 | ATPase type 13A5 | 18.3188 |
| LOC105371045 | uncharacterized LOC105371045 | 18.2596 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 18.0605 |
| RGS16 | regulator of G-protein signaling 16 | 17.6819 |
| HOPX | HOP homeobox | 17.6596 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 | 17.4473 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 17.4365 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 17.3516 |
| CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 | 17.3261 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 17.3179 |
| SLC25A18 | solute carrier family 25 (glutamate carrier), member 18 | 17.0424 |
| ESPN | espin | 16.6092 |
| CAPN13 | calpain 13 | 16.164 |
| TSPYL2 | TSPY-like 2 | 15.2254 |
| CRABP1 | cellular retinoic acid binding protein 1 | 15.0525 |
| RORC | RAR-related orphan receptor C | 13.8268 |
| C2ORF54 | chromosome 2 open reading frame 54 | 13.6198 |
| FAM84A | family with sequence similarity 84, member A | 13.3466 |
| PRRT4 | proline-rich transmembrane protein 4 | 12.7526 |
| CRABP2 | cellular retinoic acid binding protein 2 | 12.7168 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 12.6501 |
| ZBTB42 | zinc finger and BTB domain containing 42 | 12.6209 |
| GPER1 | G protein-coupled estrogen receptor 1 | 12.5415 |
| IRX3 | iroquois homeobox 3 | 12.5067 |
| STRADB | STE20-related kinase adaptor beta | 12.4731 |
| FOXO4 | forkhead box O4 | 12.4282 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 12.4062 |
| TGFB3 | transforming growth factor, beta 3 | 12.2868 |
| TRIM3 | tripartite motif containing 3 | 12.2148 |
| GJB2 | gap junction protein, beta 2, 26kDa | 11.9636 |
| FBXO2 | F-box protein 2 | 11.8781 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 | 11.8031 |
| PRSS8 | protease, serine, 8 | 11.7692 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 11.7275 |
| LRRC31 | leucine rich repeat containing 31 | 11.6883 |
| DDIT4 | DNA-damage-inducible transcript 4 | 11.6574 |
| RCAN1 | regulator of calcineurin 1 | 11.6272 |
| CCDC83 | coiled-coil domain containing 83 | 11.6001 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 11.5666 |
| CCDC159 | coiled-coil domain containing 159 | 11.2881 |
| WNT6 | wingless-type MMTV integration site family, member 6 | 11.0639 |
| CPE | carboxypeptidase E | 10.9688 |
| LINC01207 | long intergenic non-protein coding RNA 1207 | 10.9621 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 10.8541 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 10.8148 |
| APOL2 | apolipoprotein L, 2 | 10.7623 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 10.7042 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 10.6814 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 10.6814 |
| PNPLA7 | patatin-like phospholipase domain containing 7 | 10.6622 |
| CARD14 | caspase recruitment domain family, member 14 | 10.6366 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 10.488 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 10.4536 |
| MAGED2 | melanoma antigen family D2 | 10.3472 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 10.3039 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 10.2727 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 | 10.2336 |
| SLC6A19 | solute carrier family 6 (neutral amino acid transporter), member 19 | 10.1952 |
| SNN | stannin | 10.1885 |
| GRB14 | growth factor receptor-bound protein 14 | 10.172 |
| ARHGAP4 | Rho GTPase activating protein 4 | 10.1444 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 10.0945 |
| QPCT | glutaminyl-peptide cyclotransferase | 10.052 |
| C17ORF58 | chromosome 17 open reading frame 58 | 10.0246 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 9.93385 |
| CHRM1 | cholinergic receptor, muscarinic 1 | 9.93385 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 9.88224 |
| ABCC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | 9.87771 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 9.83612 |
| PROM2 | prominin 2 | 9.78811 |
| IL6R | interleukin 6 receptor | 9.78306 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 9.77235 |
| ATOH8 | atonal homolog 8 (Drosophila) | 9.76895 |
| GRAMD2 | GRAM domain containing 2 | 9.7553 |
| CREB3L4 | cAMP responsive element binding protein 3-like 4 | 9.70963 |
| FLT3 | fms-related tyrosine kinase 3 | 9.70032 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 9.60709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DOK7 | docking protein 7 | -20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -20.0 |
| PRMT6 | protein arginine methyltransferase 6 | -20.0 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -20.0 |
| CREBL2 | cAMP responsive element binding protein-like 2 | -20.0 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -20.0 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -20.0 |
| NLN | neurolysin (metallopeptidase M3 family) | -20.0 |
| ZNF492 | zinc finger protein 492 | -20.0 |
| ZNF28 | zinc finger protein 28 | -20.0 |
| CTPS1 | CTP synthase 1 | -20.0 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -20.0 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -20.0 |
| UNG | uracil-DNA glycosylase | -20.0 |
| AREG | amphiregulin | -20.0 |
| EPRS | glutamyl-prolyl-tRNA synthetase | -20.0 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -20.0 |
| ZNF681 | zinc finger protein 681 | -20.0 |
| LIF | leukemia inhibitory factor | -20.0 |
| ZNF468 | zinc finger protein 468 | -20.0 |
| GBX2 | gastrulation brain homeobox 2 | -20.0 |
| TFF1 | trefoil factor 1 | -20.0 |
| EZR | ezrin | -20.0 |
| ZNF724P | zinc finger protein 724, pseudogene | -20.0 |
| GEMIN5 | gem (nuclear organelle) associated protein 5 | -20.0 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | -20.0 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -20.0 |
| SYT16 | synaptotagmin XVI | -20.0 |
| DCDC2 | doublecortin domain containing 2 | -20.0 |
| MEF2C | myocyte enhancer factor 2C | -20.0 |
| FOXE1 | forkhead box E1 | -20.0 |
| BTC | betacellulin | -20.0 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | -19.699 |
| TUBB6 | tubulin, beta 6 class V | -19.5229 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -18.8539 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -18.8539 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -18.6778 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -18.1135 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 | -18.0969 |
| MTPN | myotrophin | -17.8097 |
| KNSTRN | kinetochore-localized astrin/SPAG5 binding protein | -17.7399 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 | -17.7033 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -17.6676 |
| FADS1 | fatty acid desaturase 1 | -17.6144 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -17.4895 |
| ERLIN1 | ER lipid raft associated 1 | -17.3788 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | -17.0292 |
| LMNB2 | lamin B2 | -16.9423 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -16.9423 |
| AMZ1 | archaelysin family metallopeptidase 1 | -16.4814 |
| MT2A | metallothionein 2A | -16.3456 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -16.164 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) | -16.0917 |
| MXD1 | MAX dimerization protein 1 | -16.0917 |
| PRSS23 | protease, serine, 23 | -15.8768 |
| RAD51AP1 | RAD51 associated protein 1 | -15.8106 |
| ZNF587B | zinc finger protein 587B | -15.7404 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -15.7114 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -15.7032 |
| DKC1 | dyskeratosis congenita 1, dyskerin | -15.6709 |
| MRPL50 | mitochondrial ribosomal protein L50 | -15.5324 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -15.4162 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | -15.3053 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -15.2863 |
| HIST3H2BB | histone cluster 3, H2bb | -15.2196 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -15.0589 |
| ZNF730 | zinc finger protein 730 | -15.0522 |
| UCK2 | uridine-cytidine kinase 2 | -14.9988 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -14.8484 |
| AMD1 | adenosylmethionine decarboxylase 1 | -14.7341 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -14.7245 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -14.6214 |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' | -14.6115 |
| METTL8 | methyltransferase like 8 | -14.5794 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) | -14.556 |
| STC2 | stanniocalcin 2 | -14.556 |
| SYPL1 | synaptophysin-like 1 | -14.466 |
| ESCO2 | establishment of sister chromatid cohesion N-acetyltransferase 2 | -14.4508 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -14.4496 |
| CDK2 | cyclin-dependent kinase 2 | -14.4433 |
| C14ORF132 | chromosome 14 open reading frame 132 | -14.0166 |
| ZNF100 | zinc finger protein 100 | -13.8808 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -13.8497 |
| DOCK4 | dedicator of cytokinesis 4 | -13.6113 |
| MPZL2 | myelin protein zero-like 2 | -13.503 |
| CDCA7L | cell division cycle associated 7-like | -13.3131 |
| LMO7 | LIM domain 7 | -13.2846 |
| ACTL6A | actin-like 6A | -13.1221 |
| HIST2H2BF | histone cluster 2, H2bf | -13.0892 |
| BYSL | bystin-like | -13.0891 |
| CCNA2 | cyclin A2 | -13.0321 |
| RPL22L1 | ribosomal protein L22-like 1 | -12.9136 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | -12.8505 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -12.8326 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -12.7844 |
| ZNF850 | zinc finger protein 850 | -12.7824 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -12.7137 |
| UTP15 | UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) | -12.6294 |
| TEX2 | testis expressed 2 | -12.6181 |
| FADS3 | fatty acid desaturase 3 | -12.5415 |
