| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ESRRA in MDA-MB-231 cell line (Study accession: SRP028155) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12249_KD_ESRRA_SRP028155 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFR3A | EFR3 homolog A (S. cerevisiae) | 20.0 |
| TRAM1 | translocation associated membrane protein 1 | 20.0 |
| LBR | lamin B receptor | 20.0 |
| ARMC1 | armadillo repeat containing 1 | 20.0 |
| RAB18 | RAB18, member RAS oncogene family | 20.0 |
| TMEM245 | transmembrane protein 245 | 20.0 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 20.0 |
| HPCAL1 | hippocalcin-like 1 | 20.0 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 20.0 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 20.0 |
| AJUBA | ajuba LIM protein | 20.0 |
| C12ORF75 | chromosome 12 open reading frame 75 | 20.0 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 20.0 |
| AOX1 | aldehyde oxidase 1 | 20.0 |
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 20.0 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 20.0 |
| C12ORF49 | chromosome 12 open reading frame 49 | 20.0 |
| FNDC3A | fibronectin type III domain containing 3A | 20.0 |
| HBEGF | heparin-binding EGF-like growth factor | 20.0 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 20.0 |
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 20.0 |
| IL6ST | interleukin 6 signal transducer | 20.0 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 20.0 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 20.0 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 20.0 |
| JOSD1 | Josephin domain containing 1 | 20.0 |
| CDK6 | cyclin-dependent kinase 6 | 20.0 |
| NUPL1 | nucleoporin like 1 | 20.0 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 20.0 |
| CNTN1 | contactin 1 | 20.0 |
| TXNRD1 | thioredoxin reductase 1 | 20.0 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 20.0 |
| COL13A1 | collagen, type XIII, alpha 1 | 20.0 |
| LIFR | leukemia inhibitory factor receptor alpha | 20.0 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 20.0 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 20.0 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 20.0 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 20.0 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 20.0 |
| RNF11 | ring finger protein 11 | 20.0 |
| NDRG1 | N-myc downstream regulated 1 | 20.0 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 20.0 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 20.0 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 20.0 |
| RC3H2 | ring finger and CCCH-type domains 2 | 20.0 |
| C5ORF51 | chromosome 5 open reading frame 51 | 20.0 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 20.0 |
| RDX | radixin | 20.0 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | 20.0 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 20.0 |
| ITGAV | integrin, alpha V | 20.0 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 20.0 |
| GLO1 | glyoxalase I | 20.0 |
| KCTD20 | potassium channel tetramerization domain containing 20 | 20.0 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 20.0 |
| NPTN | neuroplastin | 20.0 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 20.0 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 20.0 |
| FTH1 | ferritin, heavy polypeptide 1 | 20.0 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 20.0 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 20.0 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 20.0 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK | 20.0 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 20.0 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 20.0 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 20.0 |
| GHITM | growth hormone inducible transmembrane protein | 20.0 |
| TSPAN14 | tetraspanin 14 | 20.0 |
| TUBA1A | tubulin, alpha 1a | 20.0 |
| AGPS | alkylglycerone phosphate synthase | 20.0 |
| CAB39 | calcium binding protein 39 | 20.0 |
| ERO1L | ERO1-like (S. cerevisiae) | 20.0 |
| USP12 | ubiquitin specific peptidase 12 | 20.0 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 20.0 |
| CLIC4 | chloride intracellular channel 4 | 20.0 |
| CLIC1 | chloride intracellular channel 1 | 20.0 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 20.0 |
| PUM2 | pumilio RNA-binding family member 2 | 20.0 |
| REEP5 | receptor accessory protein 5 | 20.0 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 20.0 |
| NCKAP1 | NCK-associated protein 1 | 20.0 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 20.0 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 20.0 |
| CDCP1 | CUB domain containing protein 1 | 20.0 |
| CDC23 | cell division cycle 23 | 20.0 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 20.0 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 20.0 |
| NDC1 | NDC1 transmembrane nucleoporin | 20.0 |
| TMSB10 | thymosin beta 10 | 20.0 |
| PEG10 | paternally expressed 10 | 20.0 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 20.0 |
| SAMHD1 | SAM domain and HD domain 1 | 20.0 |
| ZNF367 | zinc finger protein 367 | 20.0 |
| NEK7 | NIMA-related kinase 7 | 20.0 |
| ECE1 | endothelin converting enzyme 1 | 20.0 |
| CAV2 | caveolin 2 | 20.0 |
| LMNB2 | lamin B2 | 20.0 |
| HSPB1 | heat shock 27kDa protein 1 | 20.0 |
| ACLY | ATP citrate lyase | 20.0 |
| PLS3 | plastin 3 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SBF1 | SET binding factor 1 | -20.0 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -20.0 |
| SCARB2 | scavenger receptor class B, member 2 | -20.0 |
| UNC13B | unc-13 homolog B (C. elegans) | -20.0 |
| PRMT6 | protein arginine methyltransferase 6 | -20.0 |
| ADM | adrenomedullin | -20.0 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -20.0 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -20.0 |
| P3H1 | prolyl 3-hydroxylase 1 | -20.0 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -20.0 |
| NDRG3 | NDRG family member 3 | -20.0 |
| COL8A1 | collagen, type VIII, alpha 1 | -20.0 |
| ESRRA | estrogen-related receptor alpha | -20.0 |
| TFB1M | transcription factor B1, mitochondrial | -20.0 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -20.0 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -20.0 |
| NECAP2 | NECAP endocytosis associated 2 | -20.0 |
| CWC15 | CWC15 spliceosome-associated protein | -20.0 |
| DCP1A | decapping mRNA 1A | -20.0 |
| RAB21 | RAB21, member RAS oncogene family | -20.0 |
| HIST1H2BK | histone cluster 1, H2bk | -20.0 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -20.0 |
| VRK1 | vaccinia related kinase 1 | -20.0 |
| VRK3 | vaccinia related kinase 3 | -20.0 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -20.0 |
| PTEN | phosphatase and tensin homolog | -20.0 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -20.0 |
| ABHD10 | abhydrolase domain containing 10 | -20.0 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -20.0 |
| SCAMP5 | secretory carrier membrane protein 5 | -20.0 |
| USP48 | ubiquitin specific peptidase 48 | -20.0 |
| ZPR1 | ZPR1 zinc finger | -20.0 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -20.0 |
| STX18 | syntaxin 18 | -20.0 |
| DUSP7 | dual specificity phosphatase 7 | -20.0 |
| SUDS3 | suppressor of defective silencing 3 homolog (S. cerevisiae) | -20.0 |
| UIMC1 | ubiquitin interaction motif containing 1 | -20.0 |
| TMEM2 | transmembrane protein 2 | -20.0 |
| INAFM2 | InaF-motif containing 2 | -20.0 |
| ARL5B | ADP-ribosylation factor-like 5B | -20.0 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -20.0 |
| MAX | MYC associated factor X | -20.0 |
| TBL1X | transducin (beta)-like 1X-linked | -20.0 |
| ARHGAP1 | Rho GTPase activating protein 1 | -20.0 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -20.0 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -20.0 |
| VBP1 | von Hippel-Lindau binding protein 1 | -20.0 |
| TMEM230 | transmembrane protein 230 | -20.0 |
| SNRK | SNF related kinase | -20.0 |
| MDC1 | mediator of DNA-damage checkpoint 1 | -20.0 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | -20.0 |
| GLTP | glycolipid transfer protein | -20.0 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -20.0 |
| CCL14 | chemokine (C-C motif) ligand 14 | -20.0 |
| STAMBP | STAM binding protein | -20.0 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | -20.0 |
| SLAIN1 | SLAIN motif family, member 1 | -20.0 |
| FAM20B | family with sequence similarity 20, member B | -20.0 |
| BUD13 | BUD13 homolog (S. cerevisiae) | -20.0 |
| ACO2 | aconitase 2, mitochondrial | -20.0 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -20.0 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -20.0 |
| RBM27 | RNA binding motif protein 27 | -20.0 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -20.0 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -20.0 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -20.0 |
| ABI1 | abl-interactor 1 | -20.0 |
| DDI2 | DNA-damage inducible 1 homolog 2 (S. cerevisiae) | -20.0 |
| ELP5 | elongator acetyltransferase complex subunit 5 | -20.0 |
| KLHL12 | kelch-like family member 12 | -20.0 |
| KLHL18 | kelch-like family member 18 | -20.0 |
| NKIRAS1 | NFKB inhibitor interacting Ras-like 1 | -20.0 |
| HIST1H1C | histone cluster 1, H1c | -20.0 |
| FCHSD2 | FCH and double SH3 domains 2 | -20.0 |
| TP53BP2 | tumor protein p53 binding protein 2 | -20.0 |
| GRK6 | G protein-coupled receptor kinase 6 | -20.0 |
| PRELID1 | PRELI domain containing 1 | -20.0 |
| DCAF11 | DDB1 and CUL4 associated factor 11 | -20.0 |
| YEATS4 | YEATS domain containing 4 | -20.0 |
| BRAP | BRCA1 associated protein | -20.0 |
| MICB | MHC class I polypeptide-related sequence B | -20.0 |
| TTPAL | tocopherol (alpha) transfer protein-like | -20.0 |
| C12ORF43 | chromosome 12 open reading frame 43 | -20.0 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -20.0 |
| CHPT1 | choline phosphotransferase 1 | -20.0 |
| C6ORF120 | chromosome 6 open reading frame 120 | -20.0 |
| LIN52 | lin-52 DREAM MuvB core complex component | -20.0 |
| SGSH | N-sulfoglucosamine sulfohydrolase | -20.0 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -20.0 |
| TCTN3 | tectonic family member 3 | -20.0 |
| MECOM | MDS1 and EVI1 complex locus | -20.0 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | -20.0 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -20.0 |
| RND3 | Rho family GTPase 3 | -20.0 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -20.0 |
| ZHX1 | zinc fingers and homeoboxes 1 | -20.0 |
| RPIA | ribose 5-phosphate isomerase A | -20.0 |
| SSU72 | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | -20.0 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -20.0 |
| EVI5 | ecotropic viral integration site 5 | -20.0 |
