| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting MYC in MDA-MB-231 cell line (Study accession: SRP186908) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12323_KD_MYC_SRP186908 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCD3 | phospholipase C, delta 3 | 20.0 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 20.0 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin | 20.0 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 20.0 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 20.0 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 20.0 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 20.0 |
| WTIP | Wilms tumor 1 interacting protein | 20.0 |
| FBXO32 | F-box protein 32 | 20.0 |
| ASS1 | argininosuccinate synthase 1 | 20.0 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 20.0 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 20.0 |
| PYGB | phosphorylase, glycogen; brain | 20.0 |
| MARCKSL1 | MARCKS-like 1 | 20.0 |
| TGFB2 | transforming growth factor, beta 2 | 20.0 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit | 20.0 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 20.0 |
| UNG | uracil-DNA glycosylase | 20.0 |
| SLC37A2 | solute carrier family 37 (glucose-6-phosphate transporter), member 2 | 20.0 |
| MDFI | MyoD family inhibitor | 20.0 |
| FTL | ferritin, light polypeptide | 20.0 |
| SLC41A3 | solute carrier family 41, member 3 | 20.0 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 20.0 |
| OLFML2A | olfactomedin-like 2A | 20.0 |
| PER2 | period circadian clock 2 | 20.0 |
| ANXA11 | annexin A11 | 20.0 |
| CTSD | cathepsin D | 20.0 |
| TPCN1 | two pore segment channel 1 | 20.0 |
| ITGA10 | integrin, alpha 10 | 20.0 |
| PER1 | period circadian clock 1 | 20.0 |
| PLLP | plasmolipin | 20.0 |
| ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif, 17 | 20.0 |
| RPS27 | ribosomal protein S27 | 20.0 |
| DGAT2 | diacylglycerol O-acyltransferase 2 | 20.0 |
| PLXND1 | plexin D1 | 19.699 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 19.5229 |
| REPS2 | RALBP1 associated Eps domain containing 2 | 19.5229 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 19.301 |
| PLSCR4 | phospholipid scramblase 4 | 19.0 |
| CRY1 | cryptochrome circadian clock 1 | 19.0 |
| TSKU | tsukushi, small leucine rich proteoglycan | 18.9586 |
| SPDEF | SAM pointed domain containing ETS transcription factor | 18.699 |
| CRY2 | cryptochrome circadian clock 2 | 18.6021 |
| ADAMTS15 | ADAM metallopeptidase with thrombospondin type 1 motif, 15 | 18.585 |
| DPP7 | dipeptidyl-peptidase 7 | 18.585 |
| PHPT1 | phosphohistidine phosphatase 1 | 18.4815 |
| NAGLU | N-acetylglucosaminidase, alpha | 18.3372 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 18.0362 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 17.9101 |
| RXRA | retinoid X receptor, alpha | 17.9031 |
| TBKBP1 | TBK1 binding protein 1 | 17.8962 |
| TSPO | translocator protein (18kDa) | 17.8508 |
| CPE | carboxypeptidase E | 17.8356 |
| PLIN4 | perilipin 4 | 17.8097 |
| CTSA | cathepsin A | 17.7852 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 17.7852 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 17.7399 |
| SLC38A7 | solute carrier family 38, member 7 | 17.7212 |
| NEK6 | NIMA-related kinase 6 | 17.6556 |
| TBC1D16 | TBC1 domain family, member 16 | 17.6126 |
| RAB17 | RAB17, member RAS oncogene family | 17.4672 |
| CMTM3 | CKLF-like MARVEL transmembrane domain containing 3 | 17.2924 |
| L1CAM | L1 cell adhesion molecule | 17.2782 |
| FAM102A | family with sequence similarity 102, member A | 17.2426 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase | 16.9274 |
| PODXL2 | podocalyxin-like 2 | 16.7199 |
| STEAP3 | STEAP family member 3, metalloreductase | 16.6899 |
| PTGES | prostaglandin E synthase | 16.6899 |
| FAM20C | family with sequence similarity 20, member C | 16.5907 |
| BMP1 | bone morphogenetic protein 1 | 16.5907 |
| RPS5 | ribosomal protein S5 | 16.5388 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | 16.4247 |
| ISOC2 | isochorismatase domain containing 2 | 16.343 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 16.2935 |
| GSTK1 | glutathione S-transferase kappa 1 | 16.2782 |
| PPAP2C | phosphatidic acid phosphatase type 2C | 16.2137 |
| TMEM120A | transmembrane protein 120A | 16.1283 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 16.1134 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 15.9627 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 15.9614 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 15.9505 |
| HSPG2 | heparan sulfate proteoglycan 2 | 15.8951 |
| EPAS1 | endothelial PAS domain protein 1 | 15.865 |
| ADCK3 | aarF domain containing kinase 3 | 15.7673 |
| SLC22A18 | solute carrier family 22, member 18 | 15.685 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 15.5108 |
| PHYHD1 | phytanoyl-CoA dioxygenase domain containing 1 | 15.4651 |
| NINJ1 | ninjurin 1 | 15.3847 |
| ANK1 | ankyrin 1, erythrocytic | 15.2729 |
| SHANK3 | SH3 and multiple ankyrin repeat domains 3 | 15.2268 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 15.191 |
| LOXL1 | lysyl oxidase-like 1 | 15.1829 |
| MLPH | melanophilin | 15.0697 |
| VSTM2L | V-set and transmembrane domain containing 2 like | 15.0625 |
| DEAF1 | DEAF1 transcription factor | 14.9739 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 14.832 |
| MEGF8 | multiple EGF-like-domains 8 | 14.7653 |
| ANGPTL4 | angiopoietin-like 4 | 14.7629 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 14.7496 |
| PGLS | 6-phosphogluconolactonase | 14.6098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SET | SET nuclear proto-oncogene | -20.0 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -20.0 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -20.0 |
| STC1 | stanniocalcin 1 | -20.0 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -20.0 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | -20.0 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -20.0 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -20.0 |
| MAX | MYC associated factor X | -20.0 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -20.0 |
| KLK1 | kallikrein 1 | -20.0 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -20.0 |
| PTMS | parathymosin | -20.0 |
| TMEM45A | transmembrane protein 45A | -20.0 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -20.0 |
| CD82 | CD82 molecule | -20.0 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -20.0 |
| KRT15 | keratin 15, type I | -20.0 |
| NCL | nucleolin | -20.0 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -20.0 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -20.0 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -20.0 |
| PAEP | progestagen-associated endometrial protein | -20.0 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -20.0 |
| MSN | moesin | -20.0 |
| METAP2 | methionyl aminopeptidase 2 | -20.0 |
| INSIG2 | insulin induced gene 2 | -20.0 |
| C9ORF72 | chromosome 9 open reading frame 72 | -20.0 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | -20.0 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -20.0 |
| LAMB1 | laminin, beta 1 | -20.0 |
| TFPI2 | tissue factor pathway inhibitor 2 | -20.0 |
| CA9 | carbonic anhydrase IX | -20.0 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -20.0 |
| TNS4 | tensin 4 | -20.0 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -20.0 |
| PTN | pleiotrophin | -20.0 |
| KLK2 | kallikrein-related peptidase 2 | -20.0 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | -20.0 |
| RBM25 | RNA binding motif protein 25 | -20.0 |
| PPID | peptidylprolyl isomerase D | -20.0 |
| ALDOC | aldolase C, fructose-bisphosphate | -20.0 |
| RAB3B | RAB3B, member RAS oncogene family | -20.0 |
| CYCS | cytochrome c, somatic | -19.699 |
| FRG1 | FSHD region gene 1 | -19.5229 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -19.5229 |
| C4ORF3 | chromosome 4 open reading frame 3 | -19.2218 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -19.2218 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -19.1549 |
| MNS1 | meiosis-specific nuclear structural 1 | -19.0 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -18.7959 |
| AURKA | aurora kinase A | -18.7696 |
| LMNB1 | lamin B1 | -18.6383 |
| LEO1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -18.585 |
| SKA2 | spindle and kinetochore associated complex subunit 2 | -18.4815 |
| ZNF326 | zinc finger protein 326 | -18.1805 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -18.0809 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -18.0655 |
| TNC | tenascin C | -18.0655 |
| PM20D2 | peptidase M20 domain containing 2 | -17.8962 |
| CBWD1 | COBW domain containing 1 | -17.5607 |
| PEAR1 | platelet endothelial aggregation receptor 1 | -17.0482 |
| EIF5B | eukaryotic translation initiation factor 5B | -16.8983 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -16.8742 |
| NES | nestin | -16.7185 |
| WBP5 | WW domain binding protein 5 | -16.6718 |
| FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | -16.363 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -16.343 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -16.2748 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -16.2185 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -16.164 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -16.137 |
| CBWD5 | COBW domain containing 5 | -16.0906 |
| SNX5 | sorting nexin 5 | -15.9716 |
| ERO1L | ERO1-like (S. cerevisiae) | -15.521 |
| PTMA | prothymosin, alpha | -15.5108 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -15.4844 |
| MRPL39 | mitochondrial ribosomal protein L39 | -15.4775 |
| RHEB | Ras homolog enriched in brain | -15.3189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -15.3067 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | -15.2156 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | -15.2048 |
| TSPYL2 | TSPY-like 2 | -15.1137 |
| GLO1 | glyoxalase I | -15.1003 |
| TPM3 | tropomyosin 3 | -14.9843 |
| DDRGK1 | DDRGK domain containing 1 | -14.9174 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -14.9077 |
| SMS | spermine synthase | -14.8937 |
| JRKL | JRK-like | -14.8795 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -14.8289 |
| LYAR | Ly1 antibody reactive | -14.8176 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -14.8141 |
| CCNG2 | cyclin G2 | -14.7237 |
| U2SURP | U2 snRNP-associated SURP domain containing | -14.696 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -14.6046 |
| HIAT1 | hippocampus abundant transcript 1 | -14.3189 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -14.2453 |
| TCEAL6 | transcription elongation factor A (SII)-like 6 | -14.243 |
| DEK | DEK proto-oncogene | -14.2139 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -14.1736 |
