Perturb_1236_KD_RBMX_SRP033393 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting RBMX in B-cells lymphoblastoid GM19238 cell line (Study accession: SRP033393) (PerturbAtlas)
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Genes

160 genes differentially expressed following the Perturb_1236_KD_RBMX_SRP033393 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
AKAP3 A kinase (PRKA) anchor protein 3 10.4801
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 6.88376
ZBED8 zinc finger, BED-type containing 8 6.44953
IL19 interleukin 19 4.56308
MAB21L3 mab-21-like 3 (C. elegans) 4.49869
USP6 ubiquitin specific peptidase 6 3.76712
HIST2H2BE histone cluster 2, H2be 3.69898
ZNF654 zinc finger protein 654 3.62419
KLLN killin, p53-regulated DNA replication inhibitor 3.56567
TMSB15A thymosin beta 15a 3.55047
ZBTB20 zinc finger and BTB domain containing 20 3.13791
BBS10 Bardet-Biedl syndrome 10 3.10579
HIST1H2BD histone cluster 1, H2bd 2.90312
ZNF563 zinc finger protein 563 2.85234
SLAMF6 SLAM family member 6 2.80895
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 2.78285
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.65192
ZNF229 zinc finger protein 229 2.61725
SLFN12 schlafen family member 12 2.34139
SPON1 spondin 1, extracellular matrix protein 2.34139
TSPYL4 TSPY-like 4 2.31574
ZNF221 zinc finger protein 221 2.30733
CEP19 centrosomal protein 19kDa 2.29721
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 2.24463
EDA2R ectodysplasin A2 receptor 2.01616
SLC46A3 solute carrier family 46, member 3 1.94254
TMOD1 tropomodulin 1 1.93053
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 1.85535
SPRYD4 SPRY domain containing 4 1.85043
ASTN2 astrotactin 2 1.82607
TMEM189 transmembrane protein 189 1.7876
PPP1R36 protein phosphatase 1, regulatory subunit 36 1.74323
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.73653
HIST1H2BN histone cluster 1, H2bn 1.70945
ZNF470 zinc finger protein 470 1.70945
HIST1H3A histone cluster 1, H3a 1.70945
CXXC4 CXXC finger protein 4 1.67483
EPM2AIP1 EPM2A (laforin) interacting protein 1 1.66583
ERI2 ERI1 exoribonuclease family member 2 1.66059
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.65821
MGME1 mitochondrial genome maintenance exonuclease 1 1.65821
MAGEF1 melanoma antigen family F1 1.65708
LYRM7 LYR motif containing 7 1.57656
IGF1 insulin-like growth factor 1 (somatomedin C) 1.54972
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 1.54391
CXCL9 chemokine (C-X-C motif) ligand 9 1.51392
THAP2 THAP domain containing, apoptosis associated protein 2 1.5096
HIST1H4I histone cluster 1, H4i 1.50188
ZNF770 zinc finger protein 770 1.5005
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.45712
LY75 lymphocyte antigen 75 1.44904
HEATR5A HEAT repeat containing 5A 1.44647
SPATS2 spermatogenesis associated, serine-rich 2 1.43814
LDHAL6B lactate dehydrogenase A-like 6B 1.42828
PANK1 pantothenate kinase 1 1.4112
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 1.38733
TRIM22 tripartite motif containing 22 1.37244
NBEAL1 neurobeachin-like 1 1.35568
ZNF79 zinc finger protein 79 1.31352
OPN3 opsin 3 1.30172

decreased expression

Symbol Name Standardized Value
OXSR1 oxidative stress responsive 1 -20.0
SYK spleen tyrosine kinase -20.0
RBMX RNA binding motif protein, X-linked -20.0
RBMXL1 RNA binding motif protein, X-linked-like 1 -15.1053
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -12.189
DAPK2 death-associated protein kinase 2 -11.6072
CASC5 cancer susceptibility candidate 5 -9.52582
ZBTB26 zinc finger and BTB domain containing 26 -9.1994
FAM120C family with sequence similarity 120C -6.95981
ETAA1 Ewing tumor-associated antigen 1 -6.83948
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta -6.74848
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 -6.34662
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -6.16338
KDM4D lysine (K)-specific demethylase 4D -5.39626
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -5.11377
PVRL3 poliovirus receptor-related 3 -4.66669
ZNF836 zinc finger protein 836 -4.66669
LMF1 lipase maturation factor 1 -4.65406
RFC5 replication factor C (activator 1) 5, 36.5kDa -4.53656
TMEM45A transmembrane protein 45A -4.39407
CHML choroideremia-like (Rab escort protein 2) -4.36036
ZNF493 zinc finger protein 493 -4.10669
FSD1L fibronectin type III and SPRY domain containing 1-like -3.91699
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -3.89254
PM20D1 peptidase M20 domain containing 1 -3.86278
ANO6 anoctamin 6 -3.84864
ZC4H2 zinc finger, C4H2 domain containing -3.83145
TTC26 tetratricopeptide repeat domain 26 -3.77336
DHRSX dehydrogenase/reductase (SDR family) X-linked -3.6581
PARVG parvin, gamma -3.64762
KLHL23 kelch-like family member 23 -3.4985
ZNF117 zinc finger protein 117 -3.48758
UQCRC2 ubiquinol-cytochrome c reductase core protein II -3.48758
DPYSL4 dihydropyrimidinase-like 4 -3.2149
RAB9B RAB9B, member RAS oncogene family -3.20201
TTC13 tetratricopeptide repeat domain 13 -3.17531
SGOL2 shugoshin-like 2 (S. pombe) -3.00884
CD38 CD38 molecule -2.86392
ZNF586 zinc finger protein 586 -2.85234
TMEM200A transmembrane protein 200A -2.83239
TSC22D3 TSC22 domain family, member 3 -2.81882
SELO selenoprotein O -2.80895
ARG2 arginase 2 -2.77413
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -2.76489
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -2.58254
SLC22A18 solute carrier family 22, member 18 -2.58254
TEX15 testis expressed 15 -2.58254
PHGDH phosphoglycerate dehydrogenase -2.49439
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.34139
FKBP9 FK506 binding protein 9, 63 kDa -2.2186
FOSB FBJ murine osteosarcoma viral oncogene homolog B -2.1915
ARMC5 armadillo repeat containing 5 -2.10313
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.09201
SPIDR scaffolding protein involved in DNA repair -2.08512
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.0057
ERCC8 excision repair cross-complementation group 8 -2.00471
EPHX2 epoxide hydrolase 2, cytoplasmic -1.94254
UBXN4 UBX domain protein 4 -1.88548
ZNF268 zinc finger protein 268 -1.85535
ACSS2 acyl-CoA synthetase short-chain family member 2 -1.8082
CPNE7 copine VII -1.80747
FOS FBJ murine osteosarcoma viral oncogene homolog -1.77043
PCIF1 PDX1 C-terminal inhibiting factor 1 -1.73987
KIAA0391 KIAA0391 -1.72958
E2F2 E2F transcription factor 2 -1.67101
TRAPPC12 trafficking protein particle complex 12 -1.67101
NDRG1 N-myc downstream regulated 1 -1.66689
METTL22 methyltransferase like 22 -1.65993
RAB22A RAB22A, member RAS oncogene family -1.65868
RRAD Ras-related associated with diabetes -1.63788
CASC4 cancer susceptibility candidate 4 -1.59867
MKKS McKusick-Kaufman syndrome -1.5971
ALOX5 arachidonate 5-lipoxygenase -1.59412
LBH limb bud and heart development -1.57656
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -1.56193
SCD stearoyl-CoA desaturase (delta-9-desaturase) -1.5589
ACSF2 acyl-CoA synthetase family member 2 -1.55861
STS steroid sulfatase (microsomal), isozyme S -1.55218
FAAH2 fatty acid amide hydrolase 2 -1.54433
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing -1.52242
EMID1 EMI domain containing 1 -1.5096
TMEM143 transmembrane protein 143 -1.5096
VPREB3 pre-B lymphocyte 3 -1.47183
ERMN ermin, ERM-like protein -1.46072
PODXL2 podocalyxin-like 2 -1.46072
HES6 hes family bHLH transcription factor 6 -1.44904
RRAGB Ras-related GTP binding B -1.44904
SPAG4 sperm associated antigen 4 -1.40414
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -1.40414
UBOX5 U-box domain containing 5 -1.38733
TBXAS1 thromboxane A synthase 1 (platelet) -1.38733
CD300LB CD300 molecule-like family member b -1.37947
PARVB parvin, beta -1.37244
ACOX3 acyl-CoA oxidase 3, pristanoyl -1.35568
ASPH aspartate beta-hydroxylase -1.35568
PACS2 phosphofurin acidic cluster sorting protein 2 -1.31631
TBCD tubulin folding cofactor D -1.31408
DDIT4L DNA-damage-inducible transcript 4-like -1.31212
MYADM myeloid-associated differentiation marker -1.31165
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -1.304