| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting ERO1 in MDA-MB-231 cell line (Study accession: ERP137480) (PerturbAtlas) |
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200 genes differentially expressed following the Perturb_12509_KO_ERO1_ERP137480 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC122455342 | testis-specific serine/proline-rich protein | 15.7832 |
| BMP6 | bone morphogenetic protein 6 | 13.9258 |
| C18ORF8 | chromosome 18 open reading frame 8 | 13.57 |
| GNPDA2 | glucosamine-6-phosphate deaminase 2 | 12.3566 |
| STAG2 | stromal antigen 2 | 11.6893 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 10.1967 |
| SRR | serine racemase | 10.159 |
| BAG2 | BCL2-associated athanogene 2 | 9.56742 |
| MYBBP1A | MYB binding protein (P160) 1a | 9.46483 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 8.66848 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 8.18315 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 8.16798 |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 7.90229 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 7.82675 |
| LHFPL5 | lipoma HMGIC fusion partner-like 5 | 7.54298 |
| POLH | polymerase (DNA directed), eta | 7.22261 |
| GPS2 | G protein pathway suppressor 2 | 7.1376 |
| IAH1 | isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) | 6.89846 |
| PLCG1 | phospholipase C, gamma 1 | 6.88327 |
| C12ORF73 | chromosome 12 open reading frame 73 | 6.87316 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | 6.7736 |
| SHARPIN | SHANK-associated RH domain interactor | 6.61942 |
| NPC1 | Niemann-Pick disease, type C1 | 6.50945 |
| HMGA1 | high mobility group AT-hook 1 | 6.13131 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | 6.11129 |
| MYL5 | myosin, light chain 5, regulatory | 6.09995 |
| FRMD3 | FERM domain containing 3 | 6.08534 |
| ATXN7L3B | ataxin 7-like 3B | 6.0278 |
| CNTD1 | cyclin N-terminal domain containing 1 | 6.01244 |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa | 5.91384 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 5.88678 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 5.67675 |
| ARSG | arylsulfatase G | 5.42826 |
| UHRF1BP1 | UHRF1 binding protein 1 | 5.06357 |
| PITPNA | phosphatidylinositol transfer protein, alpha | 4.92055 |
| HIST1H2BN | histone cluster 1, H2bn | 4.76249 |
| FOXH1 | forkhead box H1 | 4.61991 |
| PHF3 | PHD finger protein 3 | 4.57504 |
| XRRA1 | X-ray radiation resistance associated 1 | 4.46918 |
| APOM | apolipoprotein M | 4.45751 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 | 4.41172 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | 4.26933 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) | 4.22721 |
| HRNR | hornerin | 4.11863 |
| NOL7 | nucleolar protein 7, 27kDa | 4.00925 |
| CTNS | cystinosin, lysosomal cystine transporter | 3.96451 |
| ENO3 | enolase 3 (beta, muscle) | 3.91351 |
| SIAE | sialic acid acetylesterase | 3.81572 |
| NDRG4 | NDRG family member 4 | 3.73588 |
| SBF2 | SET binding factor 2 | 3.73588 |
| AGBL5 | ATP/GTP binding protein-like 5 | 3.72565 |
| XPO5 | exportin 5 | 3.66898 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 3.45683 |
| MED12L | mediator complex subunit 12-like | 3.39685 |
| NAPEPLD | N-acyl phosphatidylethanolamine phospholipase D | 3.37082 |
| CCDC176 | coiled-coil domain containing 176 | 3.29973 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) | 3.27489 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 | 3.2526 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 3.23131 |
| TMEM120B | transmembrane protein 120B | 3.22456 |
| MINA | MYC induced nuclear antigen | 3.20828 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | 3.18704 |
| ANO3 | anoctamin 3 | 3.13621 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 3.04103 |
| JMJD4 | jumonji domain containing 4 | 3.03031 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 2.92919 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 2.91868 |
| ARG2 | arginase 2 | 2.89422 |
| RABL2B | RAB, member of RAS oncogene family-like 2B | 2.89422 |
| C12ORF76 | chromosome 12 open reading frame 76 | 2.89422 |
| GPANK1 | G patch domain and ankyrin repeats 1 | 2.88701 |
| KATNAL2 | katanin p60 subunit A-like 2 | 2.84602 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 2.84258 |
| KIAA0895 | KIAA0895 | 2.82334 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 2.79132 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) | 2.77738 |
| GLOD4 | glyoxalase domain containing 4 | 2.76692 |
| RNF39 | ring finger protein 39 | 2.68827 |
| RBM39 | RNA binding motif protein 39 | 2.67726 |
| CDC42SE1 | CDC42 small effector 1 | 2.66398 |
| ENG | endoglin | 2.63863 |
| REST | RE1-silencing transcription factor | 2.63027 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 2.62147 |
| BOP1 | block of proliferation 1 | 2.61689 |
| RANBP9 | RAN binding protein 9 | 2.59485 |
| CEP76 | centrosomal protein 76kDa | 2.55197 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | 2.55053 |
| BRI3 | brain protein I3 | 2.50296 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 2.45453 |
| KRT8 | keratin 8, type II | 2.43427 |
| JTB | jumping translocation breakpoint | 2.42678 |
| FGF5 | fibroblast growth factor 5 | 2.41854 |
| MEA1 | male-enhanced antigen 1 | 2.41122 |
| TCHP | trichoplein, keratin filament binding | 2.40352 |
| SLC9C1 | solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 | 2.39158 |
| TUBB6 | tubulin, beta 6 class V | 2.35408 |
| TPD52L1 | tumor protein D52-like 1 | 2.34682 |
| MAK | male germ cell-associated kinase | 2.32049 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 2.31744 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.30463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLITRK6 | SLIT and NTRK-like family, member 6 | -20.0 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -18.3098 |
| KCTD15 | potassium channel tetramerization domain containing 15 | -17.9393 |
| FZD4 | frizzled class receptor 4 | -15.7832 |
| ACOT8 | acyl-CoA thioesterase 8 | -12.7137 |
| SLITRK5 | SLIT and NTRK-like family, member 5 | -12.4957 |
| PRR29 | proline rich 29 | -12.2047 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -12.2047 |
| UBN1 | ubinuclein 1 | -11.4722 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -10.9721 |
| TRIM13 | tripartite motif containing 13 | -10.2838 |
| ARRDC1 | arrestin domain containing 1 | -10.2293 |
| ATG9B | autophagy related 9B | -9.6359 |
| CCDC85B | coiled-coil domain containing 85B | -9.46483 |
| ETAA1 | Ewing tumor-associated antigen 1 | -8.98804 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | -8.84527 |
| PHOSPHO1 | phosphatase, orphan 1 | -8.38845 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -8.34751 |
| ADAMTSL4 | ADAMTS-like 4 | -7.96691 |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | -7.70384 |
| BTD | biotinidase | -7.55469 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -7.45609 |
| FAM166A | family with sequence similarity 166, member A | -7.14623 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 | -7.07067 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) | -6.85444 |
| MPI | mannose phosphate isomerase | -6.85096 |
| ADRM1 | adhesion regulating molecule 1 | -6.80516 |
| FANCC | Fanconi anemia, complementation group C | -6.80516 |
| VWA2 | von Willebrand factor A domain containing 2 | -6.45582 |
| TNC | tenascin C | -6.45582 |
| MYO16 | myosin XVI | -6.3802 |
| CATSPER1 | cation channel, sperm associated 1 | -6.33504 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -6.18428 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -6.14346 |
| KIAA1549L | KIAA1549-like | -5.89917 |
| STK24 | serine/threonine kinase 24 | -5.86775 |
| KDM1A | lysine (K)-specific demethylase 1A | -5.6991 |
| BMP8B | bone morphogenetic protein 8b | -5.64227 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -5.5889 |
| SERAC1 | serine active site containing 1 | -5.38341 |
| DNHD1 | dynein heavy chain domain 1 | -5.34287 |
| ACSM4 | acyl-CoA synthetase medium-chain family member 4 | -5.30518 |
| FAM69B | family with sequence similarity 69, member B | -5.26725 |
| CCNH | cyclin H | -5.16986 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -5.05534 |
| PPL | periplakin | -4.97048 |
| SVIL | supervillin | -4.96846 |
| CCDC129 | coiled-coil domain containing 129 | -4.95548 |
| NTMT1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | -4.85137 |
| CHKA | choline kinase alpha | -4.74046 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -4.71752 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -4.66832 |
| CSNK1D | casein kinase 1, delta | -4.61826 |
| ZNF37A | zinc finger protein 37A | -4.40133 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -4.22384 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) | -4.22367 |
| BRAT1 | BRCA1-associated ATM activator 1 | -4.1836 |
| SAV1 | salvador family WW domain containing protein 1 | -4.1142 |
| SIK3 | SIK family kinase 3 | -4.0678 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -4.013 |
| CAST | calpastatin | -4.00925 |
| CCDC69 | coiled-coil domain containing 69 | -4.00747 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -3.87584 |
| HARS | histidyl-tRNA synthetase | -3.86996 |
| GUCY2C | guanylate cyclase 2C | -3.85149 |
| NEK5 | NIMA-related kinase 5 | -3.8467 |
| RELL2 | RELT-like 2 | -3.84606 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -3.80663 |
| FAT2 | FAT atypical cadherin 2 | -3.6632 |
| NMT1 | N-myristoyltransferase 1 | -3.63894 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -3.62671 |
| PLLP | plasmolipin | -3.58947 |
| OSMR | oncostatin M receptor | -3.57659 |
| C1QL3 | complement component 1, q subcomponent-like 3 | -3.57456 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -3.5735 |
| SLAMF8 | SLAM family member 8 | -3.56067 |
| TES | testin LIM domain protein | -3.50975 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -3.47819 |
| MCC | mutated in colorectal cancers | -3.47745 |
| NDFIP1 | Nedd4 family interacting protein 1 | -3.47257 |
| C11ORF68 | chromosome 11 open reading frame 68 | -3.47136 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -3.46727 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -3.35769 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -3.3561 |
| GP6 | glycoprotein VI (platelet) | -3.25961 |
| ZNF582 | zinc finger protein 582 | -3.18856 |
| MTO1 | mitochondrial tRNA translation optimization 1 | -3.18856 |
| COL6A2 | collagen, type VI, alpha 2 | -3.1786 |
| IRF1 | interferon regulatory factor 1 | -3.13081 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | -3.08615 |
| PKD2L2 | polycystic kidney disease 2-like 2 | -3.03031 |
| FAM124A | family with sequence similarity 124A | -3.02384 |
| LOX | lysyl oxidase | -3.00365 |
| SPEF2 | sperm flagellar 2 | -2.98885 |
| ENDOG | endonuclease G | -2.97117 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -2.96839 |
| CCNI2 | cyclin I family, member 2 | -2.9563 |
| SOX9 | SRY (sex determining region Y)-box 9 | -2.893 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | -2.87822 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -2.85332 |