Perturb_12509_KO_ERO1_ERP137480 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO perturbation targeting ERO1 in MDA-MB-231 cell line (Study accession: ERP137480) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Perturb_12509_KO_ERO1_ERP137480 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
LOC122455342 testis-specific serine/proline-rich protein 15.7832
BMP6 bone morphogenetic protein 6 13.9258
C18ORF8 chromosome 18 open reading frame 8 13.57
GNPDA2 glucosamine-6-phosphate deaminase 2 12.3566
STAG2 stromal antigen 2 11.6893
RABEP1 rabaptin, RAB GTPase binding effector protein 1 10.1967
SRR serine racemase 10.159
BAG2 BCL2-associated athanogene 2 9.56742
MYBBP1A MYB binding protein (P160) 1a 9.46483
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 8.66848
IGFBP7 insulin-like growth factor binding protein 7 8.18315
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 8.16798
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 7.90229
DNAH11 dynein, axonemal, heavy chain 11 7.82675
LHFPL5 lipoma HMGIC fusion partner-like 5 7.54298
POLH polymerase (DNA directed), eta 7.22261
GPS2 G protein pathway suppressor 2 7.1376
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 6.89846
PLCG1 phospholipase C, gamma 1 6.88327
C12ORF73 chromosome 12 open reading frame 73 6.87316
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 6.7736
SHARPIN SHANK-associated RH domain interactor 6.61942
NPC1 Niemann-Pick disease, type C1 6.50945
HMGA1 high mobility group AT-hook 1 6.13131
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 6.11129
MYL5 myosin, light chain 5, regulatory 6.09995
FRMD3 FERM domain containing 3 6.08534
ATXN7L3B ataxin 7-like 3B 6.0278
CNTD1 cyclin N-terminal domain containing 1 6.01244
POLR1C polymerase (RNA) I polypeptide C, 30kDa 5.91384
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 5.88678
MALSU1 mitochondrial assembly of ribosomal large subunit 1 5.67675
ARSG arylsulfatase G 5.42826
UHRF1BP1 UHRF1 binding protein 1 5.06357
PITPNA phosphatidylinositol transfer protein, alpha 4.92055
HIST1H2BN histone cluster 1, H2bn 4.76249
FOXH1 forkhead box H1 4.61991
PHF3 PHD finger protein 3 4.57504
XRRA1 X-ray radiation resistance associated 1 4.46918
APOM apolipoprotein M 4.45751
SCUBE3 signal peptide, CUB domain, EGF-like 3 4.41172
TPGS2 tubulin polyglutamylase complex subunit 2 4.26933
MMP24 matrix metallopeptidase 24 (membrane-inserted) 4.22721
HRNR hornerin 4.11863
NOL7 nucleolar protein 7, 27kDa 4.00925
CTNS cystinosin, lysosomal cystine transporter 3.96451
ENO3 enolase 3 (beta, muscle) 3.91351
SIAE sialic acid acetylesterase 3.81572
NDRG4 NDRG family member 4 3.73588
SBF2 SET binding factor 2 3.73588
AGBL5 ATP/GTP binding protein-like 5 3.72565
XPO5 exportin 5 3.66898
DCBLD2 discoidin, CUB and LCCL domain containing 2 3.45683
MED12L mediator complex subunit 12-like 3.39685
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 3.37082
CCDC176 coiled-coil domain containing 176 3.29973
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 3.27489
GRIA4 glutamate receptor, ionotropic, AMPA 4 3.2526
LCORL ligand dependent nuclear receptor corepressor-like 3.23131
TMEM120B transmembrane protein 120B 3.22456
MINA MYC induced nuclear antigen 3.20828
ZSCAN31 zinc finger and SCAN domain containing 31 3.18704
ANO3 anoctamin 3 3.13621
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.04103
JMJD4 jumonji domain containing 4 3.03031
OARD1 O-acyl-ADP-ribose deacylase 1 2.92919
ZNHIT3 zinc finger, HIT-type containing 3 2.91868
ARG2 arginase 2 2.89422
RABL2B RAB, member of RAS oncogene family-like 2B 2.89422
C12ORF76 chromosome 12 open reading frame 76 2.89422
GPANK1 G patch domain and ankyrin repeats 1 2.88701
KATNAL2 katanin p60 subunit A-like 2 2.84602
NDEL1 nudE neurodevelopment protein 1-like 1 2.84258
KIAA0895 KIAA0895 2.82334
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 2.79132
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 2.77738
GLOD4 glyoxalase domain containing 4 2.76692
RNF39 ring finger protein 39 2.68827
RBM39 RNA binding motif protein 39 2.67726
CDC42SE1 CDC42 small effector 1 2.66398
ENG endoglin 2.63863
REST RE1-silencing transcription factor 2.63027
NQO2 NAD(P)H dehydrogenase, quinone 2 2.62147
BOP1 block of proliferation 1 2.61689
RANBP9 RAN binding protein 9 2.59485
CEP76 centrosomal protein 76kDa 2.55197
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.55053
BRI3 brain protein I3 2.50296
ACADVL acyl-CoA dehydrogenase, very long chain 2.45453
KRT8 keratin 8, type II 2.43427
JTB jumping translocation breakpoint 2.42678
FGF5 fibroblast growth factor 5 2.41854
MEA1 male-enhanced antigen 1 2.41122
TCHP trichoplein, keratin filament binding 2.40352
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 2.39158
TUBB6 tubulin, beta 6 class V 2.35408
TPD52L1 tumor protein D52-like 1 2.34682
MAK male germ cell-associated kinase 2.32049
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.31744
UGDH UDP-glucose 6-dehydrogenase 2.30463

decreased expression

Symbol Name Standardized Value
SLITRK6 SLIT and NTRK-like family, member 6 -20.0
SLC19A1 solute carrier family 19 (folate transporter), member 1 -18.3098
KCTD15 potassium channel tetramerization domain containing 15 -17.9393
FZD4 frizzled class receptor 4 -15.7832
ACOT8 acyl-CoA thioesterase 8 -12.7137
SLITRK5 SLIT and NTRK-like family, member 5 -12.4957
PRR29 proline rich 29 -12.2047
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -12.2047
UBN1 ubinuclein 1 -11.4722
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -10.9721
TRIM13 tripartite motif containing 13 -10.2838
ARRDC1 arrestin domain containing 1 -10.2293
ATG9B autophagy related 9B -9.6359
CCDC85B coiled-coil domain containing 85B -9.46483
ETAA1 Ewing tumor-associated antigen 1 -8.98804
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -8.84527
PHOSPHO1 phosphatase, orphan 1 -8.38845
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -8.34751
ADAMTSL4 ADAMTS-like 4 -7.96691
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 -7.70384
BTD biotinidase -7.55469
MPHOSPH8 M-phase phosphoprotein 8 -7.45609
FAM166A family with sequence similarity 166, member A -7.14623
CLN5 ceroid-lipofuscinosis, neuronal 5 -7.07067
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -6.85444
MPI mannose phosphate isomerase -6.85096
ADRM1 adhesion regulating molecule 1 -6.80516
FANCC Fanconi anemia, complementation group C -6.80516
VWA2 von Willebrand factor A domain containing 2 -6.45582
TNC tenascin C -6.45582
MYO16 myosin XVI -6.3802
CATSPER1 cation channel, sperm associated 1 -6.33504
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -6.18428
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -6.14346
KIAA1549L KIAA1549-like -5.89917
STK24 serine/threonine kinase 24 -5.86775
KDM1A lysine (K)-specific demethylase 1A -5.6991
BMP8B bone morphogenetic protein 8b -5.64227
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 -5.5889
SERAC1 serine active site containing 1 -5.38341
DNHD1 dynein heavy chain domain 1 -5.34287
ACSM4 acyl-CoA synthetase medium-chain family member 4 -5.30518
FAM69B family with sequence similarity 69, member B -5.26725
CCNH cyclin H -5.16986
ERAP1 endoplasmic reticulum aminopeptidase 1 -5.05534
PPL periplakin -4.97048
SVIL supervillin -4.96846
CCDC129 coiled-coil domain containing 129 -4.95548
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 -4.85137
CHKA choline kinase alpha -4.74046
SH3TC2 SH3 domain and tetratricopeptide repeats 2 -4.71752
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -4.66832
CSNK1D casein kinase 1, delta -4.61826
ZNF37A zinc finger protein 37A -4.40133
SPTAN1 spectrin, alpha, non-erythrocytic 1 -4.22384
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -4.22367
BRAT1 BRCA1-associated ATM activator 1 -4.1836
SAV1 salvador family WW domain containing protein 1 -4.1142
SIK3 SIK family kinase 3 -4.0678
RBMS1 RNA binding motif, single stranded interacting protein 1 -4.013
CAST calpastatin -4.00925
CCDC69 coiled-coil domain containing 69 -4.00747
SPINK5 serine peptidase inhibitor, Kazal type 5 -3.87584
HARS histidyl-tRNA synthetase -3.86996
GUCY2C guanylate cyclase 2C -3.85149
NEK5 NIMA-related kinase 5 -3.8467
RELL2 RELT-like 2 -3.84606
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -3.80663
FAT2 FAT atypical cadherin 2 -3.6632
NMT1 N-myristoyltransferase 1 -3.63894
CHD1 chromodomain helicase DNA binding protein 1 -3.62671
PLLP plasmolipin -3.58947
OSMR oncostatin M receptor -3.57659
C1QL3 complement component 1, q subcomponent-like 3 -3.57456
PHLDA1 pleckstrin homology-like domain, family A, member 1 -3.5735
SLAMF8 SLAM family member 8 -3.56067
TES testin LIM domain protein -3.50975
SMG6 SMG6 nonsense mediated mRNA decay factor -3.47819
MCC mutated in colorectal cancers -3.47745
NDFIP1 Nedd4 family interacting protein 1 -3.47257
C11ORF68 chromosome 11 open reading frame 68 -3.47136
KCNK12 potassium channel, two pore domain subfamily K, member 12 -3.46727
SLC30A8 solute carrier family 30 (zinc transporter), member 8 -3.35769
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -3.3561
GP6 glycoprotein VI (platelet) -3.25961
ZNF582 zinc finger protein 582 -3.18856
MTO1 mitochondrial tRNA translation optimization 1 -3.18856
COL6A2 collagen, type VI, alpha 2 -3.1786
IRF1 interferon regulatory factor 1 -3.13081
PTPRC protein tyrosine phosphatase, receptor type, C -3.08615
PKD2L2 polycystic kidney disease 2-like 2 -3.03031
FAM124A family with sequence similarity 124A -3.02384
LOX lysyl oxidase -3.00365
SPEF2 sperm flagellar 2 -2.98885
ENDOG endonuclease G -2.97117
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -2.96839
CCNI2 cyclin I family, member 2 -2.9563
SOX9 SRY (sex determining region Y)-box 9 -2.893
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) -2.87822
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.85332