Perturb_12662_KD_KPC1_SRP071659 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KD perturbation targeting KPC1 in melanoma WC00060 cell line (Study accession: SRP071659) (PerturbAtlas)
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Genes

21 genes differentially expressed following the Perturb_12662_KD_KPC1_SRP071659 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
SNX22 sorting nexin 22 14.3222
ATG10 autophagy related 10 5.23172
PKM pyruvate kinase, muscle 3.37737
S100A13 S100 calcium binding protein A13 3.17455
MXD3 MAX dimerization protein 3 3.0119
JSRP1 junctional sarcoplasmic reticulum protein 1 2.28756
DDTL D-dopachrome tautomerase-like 2.24516
FAM166A family with sequence similarity 166, member A 1.90773
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.73764
IK IK cytokine, down-regulator of HLA II 1.59302
MCMDC2 minichromosome maintenance domain containing 2 1.3965
MYL5 myosin, light chain 5, regulatory 1.37574

decreased expression

Symbol Name Standardized Value
GMPPB GDP-mannose pyrophosphorylase B -20.0
LDLRAD2 low density lipoprotein receptor class A domain containing 2 -5.30993
MYEF2 myelin expression factor 2 -3.07098
BTD biotinidase -2.58783
PGF placental growth factor -1.60349
C19ORF71 chromosome 19 open reading frame 71 -1.59302
LOC122455342 testis-specific serine/proline-rich protein -1.59302
PLLP plasmolipin -1.38117
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -1.35164