| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting SLNCR1 in melanoma WM1976 cell line (Study accession: SRP070082) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12663_KD_SLNCR1_SRP070082 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOV | nephroblastoma overexpressed | 20.0 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 20.0 |
| CLDN1 | claudin 1 | 20.0 |
| TECPR2 | tectonin beta-propeller repeat containing 2 | 20.0 |
| DESI1 | desumoylating isopeptidase 1 | 20.0 |
| ZNF367 | zinc finger protein 367 | 19.699 |
| TMEM2 | transmembrane protein 2 | 17.2132 |
| IL1RAP | interleukin 1 receptor accessory protein | 16.4078 |
| KIAA1598 | 14.6179 | |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 14.0917 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 11.937 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 11.6526 |
| SMIM15 | small integral membrane protein 15 | 11.2507 |
| JUN | jun proto-oncogene | 11.2255 |
| DENND5B | DENN/MADD domain containing 5B | 9.45047 |
| RAB15 | RAB15, member RAS oncogene family | 9.32551 |
| GXYLT1 | glucoside xylosyltransferase 1 | 8.91926 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 8.78316 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 8.49876 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 8.15199 |
| NES | nestin | 8.01784 |
| IMPAD1 | inositol monophosphatase domain containing 1 | 7.96104 |
| NOTCH1 | notch 1 | 7.69952 |
| RYK | receptor-like tyrosine kinase | 7.63024 |
| SMC1A | structural maintenance of chromosomes 1A | 7.48054 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 7.38402 |
| FAM129A | family with sequence similarity 129, member A | 7.36688 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 7.35384 |
| SDC1 | syndecan 1 | 7.3491 |
| GAS1 | growth arrest-specific 1 | 7.34779 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | 7.33373 |
| CCDC71L | coiled-coil domain containing 71-like | 7.25292 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 7.22413 |
| STX6 | syntaxin 6 | 7.11308 |
| MGAT5B | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B | 7.10414 |
| PI15 | peptidase inhibitor 15 | 7.07602 |
| HEATR1 | HEAT repeat containing 1 | 7.06814 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 7.01988 |
| JUND | jun D proto-oncogene | 6.93586 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 6.93204 |
| FN1 | fibronectin 1 | 6.66242 |
| PMP22 | peripheral myelin protein 22 | 6.63642 |
| XYLT1 | xylosyltransferase I | 6.43583 |
| OCRL | oculocerebrorenal syndrome of Lowe | 6.40681 |
| AMOTL2 | angiomotin like 2 | 6.39134 |
| RPL7L1 | ribosomal protein L7-like 1 | 6.34904 |
| GOLT1B | golgi transport 1B | 6.25997 |
| SSU72 | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 6.20485 |
| WTIP | Wilms tumor 1 interacting protein | 6.18241 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 6.14359 |
| MKRN1 | makorin ring finger protein 1 | 6.12922 |
| H1F0 | H1 histone family, member 0 | 6.10649 |
| BTG2 | BTG family, member 2 | 5.95451 |
| SLC16A6 | solute carrier family 16, member 6 | 5.92627 |
| UGT8 | UDP glycosyltransferase 8 | 5.84181 |
| LASP1 | LIM and SH3 protein 1 | 5.78371 |
| FAM198B | family with sequence similarity 198, member B | 5.65837 |
| ANXA1 | annexin A1 | 5.61808 |
| TPM4 | tropomyosin 4 | 5.5753 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 5.5684 |
| SRPR | signal recognition particle receptor (docking protein) | 5.48543 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 5.47907 |
| HDGF | hepatoma-derived growth factor | 5.45888 |
| ZMYND19 | zinc finger, MYND-type containing 19 | 5.45001 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 5.40013 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 5.33522 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 5.3329 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 5.28669 |
| LIMCH1 | LIM and calponin homology domains 1 | 5.25571 |
| H1FX | H1 histone family, member X | 5.25315 |
| BIRC5 | baculoviral IAP repeat containing 5 | 5.24923 |
| SRPRB | signal recognition particle receptor, B subunit | 5.23538 |
| CNN3 | calponin 3, acidic | 5.19601 |
| MARVELD1 | MARVEL domain containing 1 | 5.18641 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 5.11125 |
| CDV3 | CDV3 homolog (mouse) | 4.97823 |
| ECE1 | endothelin converting enzyme 1 | 4.8818 |
| GLUL | glutamate-ammonia ligase | 4.83874 |
| EPHB4 | EPH receptor B4 | 4.81048 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 4.73433 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | 4.68288 |
| PLAT | plasminogen activator, tissue | 4.67944 |
| RPUSD3 | RNA pseudouridylate synthase domain containing 3 | 4.64056 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 4.59295 |
| PLXNB2 | plexin B2 | 4.56407 |
| PITPNA | phosphatidylinositol transfer protein, alpha | 4.55795 |
| RHOA | ras homolog family member A | 4.54331 |
| CDK6 | cyclin-dependent kinase 6 | 4.50902 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 4.50527 |
| LDLR | low density lipoprotein receptor | 4.49991 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 4.49405 |
| PROM1 | prominin 1 | 4.42123 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 4.40218 |
| CROT | carnitine O-octanoyltransferase | 4.3812 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 | 4.37324 |
| TUB | tubby bipartite transcription factor | 4.34343 |
| FERMT2 | fermitin family member 2 | 4.30587 |
| MRPL34 | mitochondrial ribosomal protein L34 | 4.19764 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | 4.16117 |
| MORF4L2 | mortality factor 4 like 2 | 4.14446 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA6 | integrin, alpha 6 | -20.0 |
| CBFB | core-binding factor, beta subunit | -20.0 |
| FNDC3A | fibronectin type III domain containing 3A | -20.0 |
| GTPBP1 | GTP binding protein 1 | -20.0 |
| RAB22A | RAB22A, member RAS oncogene family | -20.0 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -20.0 |
| WWC3 | WWC family member 3 | -20.0 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -20.0 |
| IPO8 | importin 8 | -20.0 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -20.0 |
| DENND6A | DENN/MADD domain containing 6A | -20.0 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -20.0 |
| MFAP3L | microfibrillar-associated protein 3-like | -20.0 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -20.0 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -20.0 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -20.0 |
| NDC1 | NDC1 transmembrane nucleoporin | -20.0 |
| GOLM1 | golgi membrane protein 1 | -20.0 |
| ANKRD52 | ankyrin repeat domain 52 | -20.0 |
| ADCY1 | adenylate cyclase 1 (brain) | -19.699 |
| FAM134B | family with sequence similarity 134, member B | -19.5229 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -19.5229 |
| PCNX | pecanex homolog (Drosophila) | -18.8539 |
| ICK | intestinal cell (MAK-like) kinase | -18.6021 |
| SOX6 | SRY (sex determining region Y)-box 6 | -18.0809 |
| TNRC6C | trinucleotide repeat containing 6C | -17.2426 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -16.8228 |
| DLD | dihydrolipoamide dehydrogenase | -16.1218 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -15.8863 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | -15.6442 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | -15.2405 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) | -15.1417 |
| SLC39A9 | solute carrier family 39, member 9 | -14.9689 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | -14.9231 |
| ACVR2B | activin A receptor, type IIB | -14.7165 |
| NRIP3 | nuclear receptor interacting protein 3 | -14.4637 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -14.2887 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -14.2626 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -14.2626 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -14.2626 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -13.9206 |
| ASB1 | ankyrin repeat and SOCS box containing 1 | -13.8537 |
| TNIK | TRAF2 and NCK interacting kinase | -13.8493 |
| PHKB | phosphorylase kinase, beta | -13.8059 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -13.7046 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -13.4215 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -13.2931 |
| CD99L2 | CD99 molecule-like 2 | -13.2923 |
| AAK1 | AP2 associated kinase 1 | -13.2747 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -13.2241 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -12.92 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 | -12.6281 |
| PRR11 | proline rich 11 | -12.5444 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -12.4344 |
| TMEM41B | transmembrane protein 41B | -12.4232 |
| RNF2 | ring finger protein 2 | -12.2686 |
| PHF6 | PHD finger protein 6 | -12.1002 |
| ITGAV | integrin, alpha V | -11.9529 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | -11.8066 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -11.8066 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -11.7996 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -11.6526 |
| CLASP1 | cytoplasmic linker associated protein 1 | -11.4995 |
| GSKIP | GSK3B interacting protein | -11.2663 |
| SNX10 | sorting nexin 10 | -11.0725 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -11.0517 |
| YPEL2 | yippee-like 2 (Drosophila) | -10.9298 |
| CDK19 | cyclin-dependent kinase 19 | -10.879 |
| TAOK1 | TAO kinase 1 | -10.5773 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -10.449 |
| NUP50 | nucleoporin 50kDa | -10.4374 |
| BLMH | bleomycin hydrolase | -10.4374 |
| HIPK2 | homeodomain interacting protein kinase 2 | -10.2005 |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit | -10.2005 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -9.84248 |
| DOCK10 | dedicator of cytokinesis 10 | -9.6404 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -9.63508 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | -9.59966 |
| FAM217B | family with sequence similarity 217, member B | -9.58388 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 | -9.44243 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -9.40079 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit | -9.36635 |
| GPR107 | G protein-coupled receptor 107 | -9.35189 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -9.3192 |
| FRMD3 | FERM domain containing 3 | -9.1717 |
| RAB8B | RAB8B, member RAS oncogene family | -9.12012 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -9.12012 |
| BSDC1 | BSD domain containing 1 | -9.05052 |
| KCTD10 | potassium channel tetramerization domain containing 10 | -8.98276 |
| TYRO3 | TYRO3 protein tyrosine kinase | -8.84538 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | -8.82254 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | -8.6787 |
| TRIM23 | tripartite motif containing 23 | -8.63548 |
| AGPAT9 | 1-acylglycerol-3-phosphate O-acyltransferase 9 | -8.6315 |
| ZNF687 | zinc finger protein 687 | -8.50166 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | -8.41108 |
| ATXN1L | ataxin 1-like | -8.27008 |
| ATF2 | activating transcription factor 2 | -8.23502 |
| UBFD1 | ubiquitin family domain containing 1 | -8.20664 |
| PHIP | pleckstrin homology domain interacting protein | -8.19975 |
