| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting FOXA1 in MM134 cell line (Study accession: SRP313175) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12904_KD_FOXA1_SRP313175 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM120B | transmembrane protein 120B | 20.0 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria | 20.0 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 20.0 |
| ATP6V1C2 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 20.0 |
| MXD3 | MAX dimerization protein 3 | 20.0 |
| HSPB1 | heat shock 27kDa protein 1 | 20.0 |
| KRT18 | keratin 18, type I | 20.0 |
| KRT19 | keratin 19, type I | 20.0 |
| JMJD8 | jumonji domain containing 8 | 20.0 |
| KRT8 | keratin 8, type II | 20.0 |
| FOXH1 | forkhead box H1 | 20.0 |
| CCDC159 | coiled-coil domain containing 159 | 20.0 |
| SNX22 | sorting nexin 22 | 20.0 |
| IFT20 | intraflagellar transport 20 | 20.0 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | 20.0 |
| FBXL6 | F-box and leucine-rich repeat protein 6 | 20.0 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 20.0 |
| L1CAM | L1 cell adhesion molecule | 20.0 |
| C19ORF26 | chromosome 19 open reading frame 26 | 20.0 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 20.0 |
| C12ORF73 | chromosome 12 open reading frame 73 | 20.0 |
| DNASE1 | deoxyribonuclease I | 20.0 |
| PMEL | premelanosome protein | 20.0 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 20.0 |
| LYRM2 | LYR motif containing 2 | 20.0 |
| CCDC151 | coiled-coil domain containing 151 | 20.0 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 20.0 |
| APP | amyloid beta (A4) precursor protein | 20.0 |
| MROH8 | maestro heat-like repeat family member 8 | 20.0 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | 20.0 |
| LMNTD2 | lamin tail domain containing 2 | 20.0 |
| MXRA8 | matrix-remodelling associated 8 | 20.0 |
| GPS2 | G protein pathway suppressor 2 | 20.0 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like | 20.0 |
| HDDC2 | HD domain containing 2 | 20.0 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 20.0 |
| LDLRAD2 | low density lipoprotein receptor class A domain containing 2 | 20.0 |
| TMEM190 | transmembrane protein 190 | 20.0 |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | 20.0 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 20.0 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 20.0 |
| EZR | ezrin | 20.0 |
| HOOK2 | hook microtubule-tethering protein 2 | 20.0 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 | 19.3979 |
| TMEM198 | transmembrane protein 198 | 19.301 |
| FKRP | fukutin related protein | 19.0458 |
| ERCC1 | excision repair cross-complementation group 1 | 18.6198 |
| CLU | clusterin | 18.2757 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 17.983 |
| TMEM186 | transmembrane protein 186 | 17.6289 |
| ACOT2 | acyl-CoA thioesterase 2 | 16.971 |
| JSRP1 | junctional sarcoplasmic reticulum protein 1 | 16.7737 |
| MYL5 | myosin, light chain 5, regulatory | 16.7097 |
| C12ORF60 | chromosome 12 open reading frame 60 | 16.6996 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 16.5651 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 16.3193 |
| FADS1 | fatty acid desaturase 1 | 16.2582 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 16.0208 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 15.881 |
| FAM71E1 | family with sequence similarity 71, member E1 | 15.7905 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | 15.6075 |
| LY6E | lymphocyte antigen 6 complex, locus E | 15.352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 15.2975 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 15.0726 |
| UQCC2 | ubiquinol-cytochrome c reductase complex assembly factor 2 | 14.9286 |
| FASN | fatty acid synthase | 14.6747 |
| C22ORF23 | chromosome 22 open reading frame 23 | 14.4608 |
| ENO3 | enolase 3 (beta, muscle) | 14.3303 |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 14.1909 |
| EPHA1 | EPH receptor A1 | 14.0543 |
| PGF | placental growth factor | 13.9432 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 13.8336 |
| CEMP1 | cementum protein 1 | 13.7018 |
| ACTG1 | actin gamma 1 | 13.5816 |
| C5ORF45 | chromosome 5 open reading frame 45 | 13.5577 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 13.249 |
| LAMA5 | laminin, alpha 5 | 13.0625 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 12.8266 |
| PUSL1 | pseudouridylate synthase-like 1 | 12.8265 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 12.7289 |
| EVL | Enah/Vasp-like | 12.6661 |
| C9ORF43 | chromosome 9 open reading frame 43 | 12.6297 |
| CA12 | carbonic anhydrase XII | 12.5847 |
| MMEL1 | membrane metallo-endopeptidase-like 1 | 12.5724 |
| PDAP1 | PDGFA associated protein 1 | 12.3295 |
| MAX | MYC associated factor X | 12.1027 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | 12.0014 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 | 11.9344 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 11.8607 |
| TCP1 | t-complex 1 | 11.8193 |
| RAD9A | RAD9 homolog A (S. pombe) | 11.7929 |
| IL17D | interleukin 17D | 11.5718 |
| BCAS4 | breast carcinoma amplified sequence 4 | 11.5464 |
| IL17RC | interleukin 17 receptor C | 11.3863 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 11.3676 |
| KRT17 | keratin 17, type I | 11.2431 |
| ENO1 | enolase 1, (alpha) | 11.2228 |
| IGSF22 | immunoglobulin superfamily, member 22 | 11.0758 |
| GTPBP6 | GTP binding protein 6 (putative) | 10.3451 |
| HSPB8 | heat shock 22kDa protein 8 | 10.316 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPC2 | Niemann-Pick disease, type C2 | -20.0 |
| COA3 | cytochrome c oxidase assembly factor 3 | -20.0 |
| FOXA1 | forkhead box A1 | -20.0 |
| HEATR1 | HEAT repeat containing 1 | -20.0 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -20.0 |
| MFSD12 | major facilitator superfamily domain containing 12 | -20.0 |
| FAM35A | family with sequence similarity 35, member A | -20.0 |
| SOCS2 | suppressor of cytokine signaling 2 | -20.0 |
| CCDC152 | coiled-coil domain containing 152 | -20.0 |
| PSMG4 | proteasome (prosome, macropain) assembly chaperone 4 | -20.0 |
| IL7 | interleukin 7 | -20.0 |
| COL2A1 | collagen, type II, alpha 1 | -20.0 |
| HSPA12A | heat shock 70kDa protein 12A | -20.0 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -19.699 |
| ABI2 | abl-interactor 2 | -19.699 |
| SLC24A5 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 | -18.6778 |
| AATK | apoptosis-associated tyrosine kinase | -18.2076 |
| MLPH | melanophilin | -16.6094 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -16.4127 |
| CYB5R2 | cytochrome b5 reductase 2 | -15.9468 |
| CYBRD1 | cytochrome b reductase 1 | -15.1468 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 | -14.6247 |
| PPT1 | palmitoyl-protein thioesterase 1 | -13.7842 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -13.7044 |
| HID1 | HID1 domain containing | -13.2458 |
| SPAG1 | sperm associated antigen 1 | -12.5428 |
| TRPS1 | trichorhinophalangeal syndrome I | -12.4772 |
| NAMPT | nicotinamide phosphoribosyltransferase | -12.4626 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -11.9008 |
| IL1R1 | interleukin 1 receptor, type I | -11.8691 |
| HIPK2 | homeodomain interacting protein kinase 2 | -11.284 |
| VIL1 | villin 1 | -10.8456 |
| PRSS23 | protease, serine, 23 | -10.8259 |
| TPSG1 | tryptase gamma 1 | -10.4585 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -10.1509 |
| FSIP1 | fibrous sheath interacting protein 1 | -10.0194 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -9.96166 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -9.89929 |
| FOXP4 | forkhead box P4 | -9.15719 |
| MYOM3 | myomesin 3 | -8.97808 |
| CDH13 | cadherin 13 | -8.887 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -8.83833 |
| ESR1 | estrogen receptor 1 | -8.78375 |
| FZD4 | frizzled class receptor 4 | -8.76156 |
| IL18BP | interleukin 18 binding protein | -8.63006 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -8.51294 |
| HMG20B | high mobility group 20B | -8.43928 |
| WNK4 | WNK lysine deficient protein kinase 4 | -8.03216 |
| CCDC107 | coiled-coil domain containing 107 | -7.8764 |
| ORAOV1 | oral cancer overexpressed 1 | -7.87231 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -7.80853 |
| SPDEF | SAM pointed domain containing ETS transcription factor | -7.66173 |
| NKX2-3 | NK2 homeobox 3 | -7.6175 |
| CISD3 | CDGSH iron sulfur domain 3 | -7.26004 |
| RUFY2 | RUN and FYVE domain containing 2 | -7.16665 |
| LOC122455342 | testis-specific serine/proline-rich protein | -7.15902 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -7.14772 |
| CORO1B | coronin, actin binding protein, 1B | -7.1032 |
| HECTD2 | HECT domain containing E3 ubiquitin protein ligase 2 | -7.10194 |
| EFHD1 | EF-hand domain family, member D1 | -6.88162 |
| SHISA2 | shisa family member 2 | -6.84433 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -6.80806 |
| KIF12 | kinesin family member 12 | -6.79089 |
| CTTNBP2 | cortactin binding protein 2 | -6.62045 |
| SLIT1 | slit homolog 1 (Drosophila) | -6.51113 |
| SNF8 | SNF8, ESCRT-II complex subunit | -6.50695 |
| SOX4 | SRY (sex determining region Y)-box 4 | -6.23505 |
| EXOSC9 | exosome component 9 | -6.19045 |
| AGK | acylglycerol kinase | -6.14687 |
| MRPS25 | mitochondrial ribosomal protein S25 | -6.11036 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -5.85662 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -5.85589 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -5.66562 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -5.66397 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 | -5.61234 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 | -5.43564 |
| BRAT1 | BRCA1-associated ATM activator 1 | -5.40732 |
| FOXP1 | forkhead box P1 | -5.28424 |
| ZNF518A | zinc finger protein 518A | -5.28133 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | -5.15097 |
| STK32B | serine/threonine kinase 32B | -5.1405 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -5.1237 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -5.10266 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | -5.0661 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -5.06342 |
| MT2A | metallothionein 2A | -5.05387 |
| ZNF135 | zinc finger protein 135 | -5.03877 |
| JTB | jumping translocation breakpoint | -4.94315 |
| LCTL | lactase-like | -4.93874 |
| ARFGEF3 | ARFGEF family member 3 | -4.90698 |
| MAPK10 | mitogen-activated protein kinase 10 | -4.89056 |
| IER3 | immediate early response 3 | -4.88442 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -4.85311 |
| MKI67 | marker of proliferation Ki-67 | -4.85236 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -4.83197 |
| C10ORF82 | chromosome 10 open reading frame 82 | -4.79716 |
| CDK6 | cyclin-dependent kinase 6 | -4.74823 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -4.6876 |
| ITGA10 | integrin, alpha 10 | -4.67831 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -4.6383 |
