| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KD perturbation targeting ALKBH5 in MOLM-13 cell line (Study accession: SRP247667) (PerturbAtlas) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Perturb_12951_KD_ALKBH5_SRP247667 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 | 10.9299 |
| THUMPD1 | THUMP domain containing 1 | 10.9017 |
| PSAP | prosaposin | 9.29381 |
| TTYH1 | tweety family member 1 | 7.60264 |
| NTNG1 | netrin G1 | 7.22516 |
| FTL | ferritin, light polypeptide | 7.074 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) | 6.9677 |
| PRTN3 | proteinase 3 | 6.74328 |
| DEXI | Dexi homolog (mouse) | 6.55667 |
| FAM160B2 | family with sequence similarity 160, member B2 | 5.58086 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 5.22485 |
| FLNA | filamin A, alpha | 5.17675 |
| PVRL3 | poliovirus receptor-related 3 | 5.14144 |
| LYZ | lysozyme | 5.13359 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 5.11012 |
| AHNAK2 | AHNAK nucleoprotein 2 | 5.09232 |
| TIFAB | TRAF-interacting protein with forkhead-associated domain, family member B | 4.65094 |
| NPB | neuropeptide B | 4.53964 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 4.53626 |
| HYI | hydroxypyruvate isomerase (putative) | 4.44201 |
| PPP1R27 | protein phosphatase 1, regulatory subunit 27 | 4.41014 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 4.29503 |
| RNF213 | ring finger protein 213 | 4.29503 |
| GRN | granulin | 4.15049 |
| PLEK | pleckstrin | 4.00318 |
| ALOX12 | arachidonate 12-lipoxygenase | 3.97501 |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 | 3.93997 |
| ODF3B | outer dense fiber of sperm tails 3B | 3.93983 |
| PLTP | phospholipid transfer protein | 3.88845 |
| SLC22A16 | solute carrier family 22 (organic cation/carnitine transporter), member 16 | 3.87458 |
| CST3 | cystatin C | 3.83797 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 3.82807 |
| TRIM46 | tripartite motif containing 46 | 3.58183 |
| DXO | decapping exoribonuclease | 3.55008 |
| SLA | Src-like-adaptor | 3.55008 |
| TMEM115 | transmembrane protein 115 | 3.54353 |
| SRGN | serglycin | 3.53006 |
| DNAJB13 | DnaJ (Hsp40) homolog, subfamily B, member 13 | 3.45496 |
| ZNF394 | zinc finger protein 394 | 3.43267 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 3.41085 |
| PCGF3 | polycomb group ring finger 3 | 3.3894 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 3.26253 |
| HDAC9 | histone deacetylase 9 | 3.24777 |
| BBC3 | BCL2 binding component 3 | 3.20593 |
| FAM20C | family with sequence similarity 20, member C | 3.02266 |
| S100A11 | S100 calcium binding protein A11 | 3.02114 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 2.98295 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide | 2.97732 |
| CCR2 | chemokine (C-C motif) receptor 2 | 2.88091 |
| TYMP | thymidine phosphorylase | 2.86445 |
| CNN2 | calponin 2 | 2.85089 |
| METRN | meteorin, glial cell differentiation regulator | 2.82746 |
| RPL13 | ribosomal protein L13 | 2.82214 |
| RPS19 | ribosomal protein S19 | 2.81974 |
| PARP10 | poly (ADP-ribose) polymerase family, member 10 | 2.80036 |
| TRPT1 | tRNA phosphotransferase 1 | 2.79765 |
| CHCHD10 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 2.76207 |
| ELANE | elastase, neutrophil expressed | 2.73355 |
| SERF2 | small EDRK-rich factor 2 | 2.73355 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 2.64619 |
| TMSB4X | thymosin beta 4, X-linked | 2.62413 |
| SERINC4 | serine incorporator 4 | 2.59837 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | 2.59691 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 2.59335 |
| BSN | bassoon presynaptic cytomatrix protein | 2.53762 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 2.51829 |
| ZNF469 | zinc finger protein 469 | 2.51178 |
| RNASEK | ribonuclease, RNase K | 2.48579 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit | 2.44614 |
| TYK2 | tyrosine kinase 2 | 2.40257 |
| LINGO3 | leucine rich repeat and Ig domain containing 3 | 2.39134 |
| TTYH3 | tweety family member 3 | 2.38287 |
| LIMA1 | LIM domain and actin binding 1 | 2.37686 |
| GAA | glucosidase, alpha; acid | 2.35137 |
| FERMT3 | fermitin family member 3 | 2.34402 |
| SAMHD1 | SAM domain and HD domain 1 | 2.34215 |
| CYP2F1 | cytochrome P450, family 2, subfamily F, polypeptide 1 | 2.33878 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 | 2.32944 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 2.31424 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.29954 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 2.27758 |
| FOXH1 | forkhead box H1 | 2.23749 |
| TTN | titin | 2.22611 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | 2.22146 |
| MRAP | melanocortin 2 receptor accessory protein | 2.19031 |
| RAB26 | RAB26, member RAS oncogene family | 2.16437 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) | 2.16437 |
| CTSD | cathepsin D | 2.16266 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 | 2.12408 |
| TPM4 | tropomyosin 4 | 2.11366 |
| DBNL | drebrin-like | 2.08746 |
| SLAMF9 | SLAM family member 9 | 2.08746 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 2.08526 |
| C10ORF105 | chromosome 10 open reading frame 105 | 2.07999 |
| CCDC78 | coiled-coil domain containing 78 | 2.06186 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | 2.05864 |
| GRTP1 | growth hormone regulated TBC protein 1 | 2.0458 |
| RPL37A | ribosomal protein L37a | 2.02861 |
| WDR24 | WD repeat domain 24 | 2.02669 |
| RANGRF | RAN guanine nucleotide release factor | 2.01229 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS8 | integrator complex subunit 8 | -20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -20.0 |
| ENOSF1 | enolase superfamily member 1 | -20.0 |
| TRIM59 | tripartite motif containing 59 | -20.0 |
| MKI67 | marker of proliferation Ki-67 | -20.0 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -19.2218 |
| EXOSC9 | exosome component 9 | -17.1662 |
| MPO | myeloperoxidase | -11.3944 |
| FAM149B1 | family with sequence similarity 149, member B1 | -11.2692 |
| TMPO | thymopoietin | -10.9809 |
| FBXO22 | F-box protein 22 | -10.7065 |
| MAPK7 | mitogen-activated protein kinase 7 | -10.5496 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | -10.2178 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -9.81294 |
| HMGB2 | high mobility group box 2 | -9.6391 |
| POLR3H | polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) | -9.60679 |
| LRRC41 | leucine rich repeat containing 41 | -9.27401 |
| CENPF | centromere protein F, 350/400kDa | -9.2116 |
| VIL1 | villin 1 | -9.1379 |
| GYG1 | glycogenin 1 | -9.09888 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -8.60492 |
| PAQR4 | progestin and adipoQ receptor family member IV | -8.24941 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -8.22836 |
| MRPS18C | mitochondrial ribosomal protein S18C | -8.12402 |
| MTMR2 | myotubularin related protein 2 | -7.84542 |
| VRK2 | vaccinia related kinase 2 | -7.77943 |
| SMC4 | structural maintenance of chromosomes 4 | -7.62976 |
| ADCY3 | adenylate cyclase 3 | -7.38205 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | -7.16948 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -6.77986 |
| C1QL3 | complement component 1, q subcomponent-like 3 | -6.60164 |
| STMN1 | stathmin 1 | -6.56703 |
| BBIP1 | BBSome interacting protein 1 | -6.51469 |
| DEK | DEK proto-oncogene | -6.50434 |
| C3ORF80 | chromosome 3 open reading frame 80 | -6.50434 |
| MFSD6 | major facilitator superfamily domain containing 6 | -6.29026 |
| LYRM5 | LYR motif containing 5 | -5.97311 |
| MCM3 | minichromosome maintenance complex component 3 | -5.86117 |
| KIF7 | kinesin family member 7 | -5.80589 |
| IFT80 | intraflagellar transport 80 | -5.74547 |
| MTIF3 | mitochondrial translational initiation factor 3 | -5.60563 |
| VAT1L | vesicle amine transport 1-like | -5.60288 |
| OTUD4 | OTU deubiquitinase 4 | -5.59523 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | -5.543 |
| CLCC1 | chloride channel CLIC-like 1 | -5.543 |
| EML5 | echinoderm microtubule associated protein like 5 | -5.48125 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -5.43177 |
| B3GAT2 | beta-1,3-glucuronyltransferase 2 | -5.42557 |
| POLG | polymerase (DNA directed), gamma | -5.28703 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -5.27466 |
| PRIMPOL | primase and polymerase (DNA-directed) | -5.22112 |
| MCM4 | minichromosome maintenance complex component 4 | -5.20925 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -5.13886 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -4.9802 |
| UBE2A | ubiquitin-conjugating enzyme E2A | -4.96076 |
| TPX2 | TPX2, microtubule-associated | -4.8513 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -4.78278 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -4.72145 |
| C3ORF17 | chromosome 3 open reading frame 17 | -4.68185 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) | -4.58611 |
| RAD9A | RAD9 homolog A (S. pombe) | -4.53556 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -4.46131 |
| LPO | lactoperoxidase | -4.39944 |
| AKTIP | AKT interacting protein | -4.37154 |
| ACOT13 | acyl-CoA thioesterase 13 | -4.35415 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -4.30455 |
| FANCD2OS | FANCD2 opposite strand | -4.30225 |
| PMCH | pro-melanin-concentrating hormone | -4.28024 |
| SYCP3 | synaptonemal complex protein 3 | -4.21864 |
| FANCL | Fanconi anemia, complementation group L | -4.19544 |
| GLIPR1 | GLI pathogenesis-related 1 | -4.10901 |
| LHFPL5 | lipoma HMGIC fusion partner-like 5 | -4.10228 |
| CCL15 | chemokine (C-C motif) ligand 15 | -4.05945 |
| RNF214 | ring finger protein 214 | -4.05465 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -4.01743 |
| GLRX2 | glutaredoxin 2 | -3.99374 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | -3.96072 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -3.84929 |
| PMEL | premelanosome protein | -3.84929 |
| POU5F1 | POU class 5 homeobox 1 | -3.84929 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -3.72307 |
| PIH1D2 | PIH1 domain containing 2 | -3.68314 |
| DCLRE1C | DNA cross-link repair 1C | -3.67496 |
| FBXO11 | F-box protein 11 | -3.60599 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -3.60518 |
| AES | amino-terminal enhancer of split | -3.59836 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -3.56622 |
| LRRC39 | leucine rich repeat containing 39 | -3.55552 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -3.5408 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 | -3.52939 |
| WSB2 | WD repeat and SOCS box containing 2 | -3.52831 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -3.46214 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -3.45105 |
| MCM7 | minichromosome maintenance complex component 7 | -3.42832 |
| MIA3 | melanoma inhibitory activity family, member 3 | -3.4172 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | -3.41301 |
| ATG7 | autophagy related 7 | -3.41085 |
| SYNC | syncoilin, intermediate filament protein | -3.38952 |
| C6ORF120 | chromosome 6 open reading frame 120 | -3.33195 |
| ZWINT | ZW10 interacting kinetochore protein | -3.32242 |
