| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting IGF2BP2 in MONO-MAC-6 cell line (Study accession: SRP365416) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_12972_KO_IGF2BP2_SRP365416 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | 20.0 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 20.0 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 20.0 |
| RTN4 | reticulon 4 | 20.0 |
| LYST | lysosomal trafficking regulator | 20.0 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 20.0 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 20.0 |
| CD164 | CD164 molecule, sialomucin | 20.0 |
| PLIN2 | perilipin 2 | 20.0 |
| JUNB | jun B proto-oncogene | 20.0 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 20.0 |
| IL17RA | interleukin 17 receptor A | 20.0 |
| ARHGAP30 | Rho GTPase activating protein 30 | 20.0 |
| MSN | moesin | 20.0 |
| CD63 | CD63 molecule | 20.0 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 20.0 |
| TPM4 | tropomyosin 4 | 20.0 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 20.0 |
| BSG | basigin (Ok blood group) | 20.0 |
| IRS2 | insulin receptor substrate 2 | 20.0 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 20.0 |
| HEXB | hexosaminidase B (beta polypeptide) | 20.0 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 20.0 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 20.0 |
| ATP11A | ATPase, class VI, type 11A | 20.0 |
| PLEC | plectin | 20.0 |
| SRPR | signal recognition particle receptor (docking protein) | 20.0 |
| METTL9 | methyltransferase like 9 | 20.0 |
| PTK2B | protein tyrosine kinase 2 beta | 20.0 |
| TMEM170B | transmembrane protein 170B | 20.0 |
| CCND3 | cyclin D3 | 20.0 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 20.0 |
| HSPA8 | heat shock 70kDa protein 8 | 20.0 |
| EMILIN2 | elastin microfibril interfacer 2 | 20.0 |
| TAPBP | TAP binding protein (tapasin) | 20.0 |
| SRGN | serglycin | 20.0 |
| TAGLN2 | transgelin 2 | 20.0 |
| PGD | phosphogluconate dehydrogenase | 20.0 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 20.0 |
| CD93 | CD93 molecule | 20.0 |
| TGOLN2 | trans-golgi network protein 2 | 20.0 |
| LDHA | lactate dehydrogenase A | 20.0 |
| LAPTM5 | lysosomal protein transmembrane 5 | 20.0 |
| MBNL1 | muscleblind-like splicing regulator 1 | 20.0 |
| CLTC | clathrin, heavy chain (Hc) | 20.0 |
| C17ORF62 | chromosome 17 open reading frame 62 | 20.0 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 20.0 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 20.0 |
| FOSL2 | FOS-like antigen 2 | 20.0 |
| SPI1 | Spi-1 proto-oncogene | 20.0 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 20.0 |
| FERMT3 | fermitin family member 3 | 20.0 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 20.0 |
| MTPN | myotrophin | 20.0 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 20.0 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 20.0 |
| TMSB4X | thymosin beta 4, X-linked | 20.0 |
| FAM101B | family with sequence similarity 101, member B | 20.0 |
| WDR1 | WD repeat domain 1 | 20.0 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 20.0 |
| NUP210 | nucleoporin 210kDa | 20.0 |
| LYZ | lysozyme | 20.0 |
| CTSZ | cathepsin Z | 20.0 |
| CTSB | cathepsin B | 20.0 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 20.0 |
| IGF2R | insulin-like growth factor 2 receptor | 20.0 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 20.0 |
| PPT1 | palmitoyl-protein thioesterase 1 | 20.0 |
| FTL | ferritin, light polypeptide | 20.0 |
| HLA-A | major histocompatibility complex, class I, A | 20.0 |
| ACTN4 | actinin, alpha 4 | 20.0 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 20.0 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 20.0 |
| CTSA | cathepsin A | 20.0 |
| PRSS8 | protease, serine, 8 | 20.0 |
| CST7 | cystatin F (leukocystatin) | 20.0 |
| ANXA2 | annexin A2 | 20.0 |
| ANXA5 | annexin A5 | 20.0 |
| ANPEP | alanyl (membrane) aminopeptidase | 20.0 |
| ZFP36 | ZFP36 ring finger protein | 20.0 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 20.0 |
| DGKZ | diacylglycerol kinase, zeta | 20.0 |
| GRN | granulin | 20.0 |
| MYO1F | myosin IF | 20.0 |
| CAPG | capping protein (actin filament), gelsolin-like | 20.0 |
| IL6R | interleukin 6 receptor | 20.0 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 20.0 |
| LAMP1 | lysosomal-associated membrane protein 1 | 20.0 |
| PKM | pyruvate kinase, muscle | 20.0 |
| B2M | beta-2-microglobulin | 20.0 |
| PSAP | prosaposin | 20.0 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 20.0 |
| LMNA | lamin A/C | 20.0 |
| HIP1 | huntingtin interacting protein 1 | 20.0 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 20.0 |
| LPXN | leupaxin | 20.0 |
| HLA-C | major histocompatibility complex, class I, C | 20.0 |
| JUN | jun proto-oncogene | 20.0 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 20.0 |
| S100A9 | S100 calcium binding protein A9 | 20.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRDM8 | PR domain containing 8 | -20.0 |
| TEC | tec protein tyrosine kinase | -20.0 |
| PDZD7 | PDZ domain containing 7 | -20.0 |
| FAM105A | family with sequence similarity 105, member A | -20.0 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -20.0 |
| MRPL51 | mitochondrial ribosomal protein L51 | -20.0 |
| RWDD1 | RWD domain containing 1 | -20.0 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -20.0 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) | -20.0 |
| ZDHHC9 | zinc finger, DHHC-type containing 9 | -20.0 |
| CCPG1 | cell cycle progression 1 | -20.0 |
| MATK | megakaryocyte-associated tyrosine kinase | -20.0 |
| CFAP20 | cilia and flagella associated protein 20 | -20.0 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -20.0 |
| ZNF260 | zinc finger protein 260 | -20.0 |
| MYO10 | myosin X | -20.0 |
| GRPEL2 | GrpE-like 2, mitochondrial (E. coli) | -20.0 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -20.0 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -20.0 |
| TUB | tubby bipartite transcription factor | -20.0 |
| GUCY2C | guanylate cyclase 2C | -20.0 |
| CA8 | carbonic anhydrase VIII | -20.0 |
| SFXN2 | sideroflexin 2 | -20.0 |
| CNN3 | calponin 3, acidic | -20.0 |
| TRIM13 | tripartite motif containing 13 | -20.0 |
| LOC102724560 | cystathionine beta-synthase | -20.0 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 | -20.0 |
| NLN | neurolysin (metallopeptidase M3 family) | -20.0 |
| MOCOS | molybdenum cofactor sulfurase | -20.0 |
| GPSM2 | G-protein signaling modulator 2 | -20.0 |
| MFSD3 | major facilitator superfamily domain containing 3 | -20.0 |
| TNIK | TRAF2 and NCK interacting kinase | -20.0 |
| COMMD8 | COMM domain containing 8 | -20.0 |
| NAT8L | N-acetyltransferase 8-like (GCN5-related, putative) | -20.0 |
| EMID1 | EMI domain containing 1 | -20.0 |
| CLDN10 | claudin 10 | -20.0 |
| MRS2 | MRS2 magnesium transporter | -20.0 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -20.0 |
| SETDB2 | SET domain, bifurcated 2 | -20.0 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | -20.0 |
| NEXN | nexilin (F actin binding protein) | -20.0 |
| NCALD | neurocalcin delta | -20.0 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -20.0 |
| RTKN2 | rhotekin 2 | -20.0 |
| WDR35 | WD repeat domain 35 | -20.0 |
| CTH | cystathionine gamma-lyase | -20.0 |
| CLGN | calmegin | -20.0 |
| MEX3A | mex-3 RNA binding family member A | -20.0 |
| UBLCP1 | ubiquitin-like domain containing CTD phosphatase 1 | -20.0 |
| BRIX1 | BRX1, biogenesis of ribosomes | -20.0 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | -20.0 |
| SERINC5 | serine incorporator 5 | -20.0 |
| PBK | PDZ binding kinase | -20.0 |
| PALM | paralemmin | -20.0 |
| HHLA2 | HERV-H LTR-associating 2 | -20.0 |
| C11ORF95 | chromosome 11 open reading frame 95 | -20.0 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -20.0 |
| TFB2M | transcription factor B2, mitochondrial | -20.0 |
| RGS16 | regulator of G-protein signaling 16 | -20.0 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -20.0 |
| NEK3 | NIMA-related kinase 3 | -20.0 |
| PTGR1 | prostaglandin reductase 1 | -20.0 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -20.0 |
| GPN1 | GPN-loop GTPase 1 | -20.0 |
| RAB33A | RAB33A, member RAS oncogene family | -20.0 |
| TTC28 | tetratricopeptide repeat domain 28 | -20.0 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | -20.0 |
| C4ORF32 | chromosome 4 open reading frame 32 | -20.0 |
| NFYC | nuclear transcription factor Y, gamma | -20.0 |
| CTSV | cathepsin V | -20.0 |
| AFF3 | AF4/FMR2 family, member 3 | -20.0 |
| DLX6 | distal-less homeobox 6 | -20.0 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | -20.0 |
| CHST10 | carbohydrate sulfotransferase 10 | -20.0 |
| NDFIP2 | Nedd4 family interacting protein 2 | -20.0 |
| ECE1 | endothelin converting enzyme 1 | -20.0 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -20.0 |
| SPNS3 | spinster homolog 3 (Drosophila) | -20.0 |
| TGM5 | transglutaminase 5 | -20.0 |
| NOL10 | nucleolar protein 10 | -20.0 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -20.0 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -20.0 |
| KLHL23 | kelch-like family member 23 | -20.0 |
| LPO | lactoperoxidase | -20.0 |
| CD38 | CD38 molecule | -20.0 |
| NKD2 | naked cuticle homolog 2 (Drosophila) | -20.0 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -20.0 |
| CD8A | CD8a molecule | -20.0 |
| ADM2 | adrenomedullin 2 | -20.0 |
| SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 | -20.0 |
| CPM | carboxypeptidase M | -20.0 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | -20.0 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase | -20.0 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -20.0 |
| EXOSC8 | exosome component 8 | -20.0 |
| CEP70 | centrosomal protein 70kDa | -20.0 |
| BLVRA | biliverdin reductase A | -20.0 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -20.0 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -20.0 |
| EXOC6 | exocyst complex component 6 | -20.0 |
