| Dataset | PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | KO perturbation targeting ALOX5 in monocytic cell line Mono Mac 6 (MM6) cell line (Study accession: SRP367905) (PerturbAtlas) |
| Similar Terms | |
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200 genes differentially expressed following the Perturb_13010_KO_ALOX5_SRP367905 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDCD2 | NudC domain containing 2 | 20.0 |
| TTN | titin | 20.0 |
| NME9 | NME/NM23 family member 9 | 20.0 |
| ATG10 | autophagy related 10 | 20.0 |
| SLIRP | SRA stem-loop interacting RNA binding protein | 20.0 |
| LYST | lysosomal trafficking regulator | 20.0 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 20.0 |
| COX20 | COX20 cytochrome c oxidase assembly factor | 20.0 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 20.0 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 20.0 |
| ASB14 | ankyrin repeat and SOCS box containing 14 | 20.0 |
| TUBB6 | tubulin, beta 6 class V | 20.0 |
| RABGAP1L | RAB GTPase activating protein 1-like | 20.0 |
| USP50 | ubiquitin specific peptidase 50 | 20.0 |
| SLC39A9 | solute carrier family 39, member 9 | 20.0 |
| OGN | osteoglycin | 20.0 |
| GPR22 | G protein-coupled receptor 22 | 20.0 |
| MFAP1 | microfibrillar-associated protein 1 | 20.0 |
| ASPN | asporin | 20.0 |
| EML5 | echinoderm microtubule associated protein like 5 | 20.0 |
| HEATR1 | HEAT repeat containing 1 | 20.0 |
| PRPF39 | pre-mRNA processing factor 39 | 20.0 |
| GLS | glutaminase | 20.0 |
| MTMR2 | myotubularin related protein 2 | 20.0 |
| GNPDA2 | glucosamine-6-phosphate deaminase 2 | 20.0 |
| TATDN1 | TatD DNase domain containing 1 | 20.0 |
| SH3D19 | SH3 domain containing 19 | 20.0 |
| MCMDC2 | minichromosome maintenance domain containing 2 | 20.0 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 20.0 |
| GYG1 | glycogenin 1 | 20.0 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 20.0 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | 20.0 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | 20.0 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 20.0 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 20.0 |
| DNM2 | dynamin 2 | 20.0 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 20.0 |
| BBIP1 | BBSome interacting protein 1 | 20.0 |
| PMPCB | peptidase (mitochondrial processing) beta | 20.0 |
| CCDC103 | coiled-coil domain containing 103 | 20.0 |
| WDR38 | WD repeat domain 38 | 20.0 |
| FAM175A | family with sequence similarity 175, member A | 20.0 |
| CFAP126 | cilia and flagella associated protein 126 | 20.0 |
| CPM | carboxypeptidase M | 20.0 |
| B2M | beta-2-microglobulin | 20.0 |
| GLRX5 | glutaredoxin 5 | 20.0 |
| MTFR1 | mitochondrial fission regulator 1 | 20.0 |
| KCP | kielin/chordin-like protein | 20.0 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 20.0 |
| RPS29 | ribosomal protein S29 | 20.0 |
| DONSON | downstream neighbor of SON | 20.0 |
| CCDC73 | coiled-coil domain containing 73 | 20.0 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 20.0 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 20.0 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 20.0 |
| GFM2 | G elongation factor, mitochondrial 2 | 20.0 |
| LYZ | lysozyme | 20.0 |
| OMD | osteomodulin | 20.0 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 20.0 |
| RUFY2 | RUN and FYVE domain containing 2 | 20.0 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 20.0 |
| INTS8 | integrator complex subunit 8 | 20.0 |
| SPAG1 | sperm associated antigen 1 | 20.0 |
| BOLA1 | bolA family member 1 | 20.0 |
| HACD4 | 3-hydroxyacyl-CoA dehydratase 4 | 20.0 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 20.0 |
| CD302 | CD302 molecule | 20.0 |
| LRRC39 | leucine rich repeat containing 39 | 20.0 |
| FAM227B | family with sequence similarity 227, member B | 20.0 |
| USP34 | ubiquitin specific peptidase 34 | 20.0 |
| C17ORF104 | chromosome 17 open reading frame 104 | 20.0 |
| NUP88 | nucleoporin 88kDa | 20.0 |
| NKIRAS1 | NFKB inhibitor interacting Ras-like 1 | 19.699 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 19.699 |
| GLIPR1 | GLI pathogenesis-related 1 | 19.5229 |
| MTIF3 | mitochondrial translational initiation factor 3 | 19.0 |
| CNTD1 | cyclin N-terminal domain containing 1 | 18.8239 |
| METTL5 | methyltransferase like 5 | 18.7212 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 18.7212 |
| TBCE | tubulin folding cofactor E | 18.585 |
| CTBP2 | C-terminal binding protein 2 | 18.5686 |
| VRK2 | vaccinia related kinase 2 | 18.4089 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 18.3665 |
| RAD17 | RAD17 homolog (S. pombe) | 18.2757 |
| LINGO3 | leucine rich repeat and Ig domain containing 3 | 18.1805 |
| COG5 | component of oligomeric golgi complex 5 | 18.0655 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 18.0555 |
| HLA-B | major histocompatibility complex, class I, B | 17.8447 |
| TPT1 | tumor protein, translationally-controlled 1 | 17.5129 |
| MRRF | mitochondrial ribosome recycling factor | 17.4685 |
| RPL31 | ribosomal protein L31 | 17.3904 |
| UBN1 | ubinuclein 1 | 17.3565 |
| CLEC1B | C-type lectin domain family 1, member B | 17.2823 |
| CLVS1 | clavesin 1 | 17.1733 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) | 16.9731 |
| FTL | ferritin, light polypeptide | 16.9582 |
| CCDC88A | coiled-coil domain containing 88A | 16.8099 |
| WDPCP | WD repeat containing planar cell polarity effector | 16.7956 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 16.7602 |
| FAM196B | family with sequence similarity 196, member B | 16.6964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NUMA1 | nuclear mitotic apparatus protein 1 | -20.0 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -20.0 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -20.0 |
| TRIM17 | tripartite motif containing 17 | -20.0 |
| KHNYN | KH and NYN domain containing | -20.0 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) | -20.0 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | -20.0 |
| PLIN4 | perilipin 4 | -20.0 |
| CLU | clusterin | -20.0 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -20.0 |
| TMEM262 | transmembrane protein 262 | -20.0 |
| MEA1 | male-enhanced antigen 1 | -20.0 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | -20.0 |
| GMPPB | GDP-mannose pyrophosphorylase B | -20.0 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -20.0 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | -20.0 |
| GPANK1 | G patch domain and ankyrin repeats 1 | -20.0 |
| TRIM46 | tripartite motif containing 46 | -20.0 |
| DBF4 | DBF4 zinc finger | -20.0 |
| GOLGA6L7P | golgin A6 family-like 7, pseudogene | -20.0 |
| C1ORF54 | chromosome 1 open reading frame 54 | -20.0 |
| CISD3 | CDGSH iron sulfur domain 3 | -20.0 |
| FBXO24 | F-box protein 24 | -20.0 |
| LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | -20.0 |
| LAMA5 | laminin, alpha 5 | -20.0 |
| C15ORF62 | chromosome 15 open reading frame 62 | -20.0 |
| GPR37L1 | G protein-coupled receptor 37 like 1 | -20.0 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | -20.0 |
| ABCC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | -20.0 |
| BCAN | brevican | -20.0 |
| ORC4 | origin recognition complex, subunit 4 | -20.0 |
| NOP16 | NOP16 nucleolar protein | -20.0 |
| LENG9 | leukocyte receptor cluster (LRC) member 9 | -20.0 |
| PTOV1 | prostate tumor overexpressed 1 | -20.0 |
| ZCWPW2 | zinc finger, CW type with PWWP domain 2 | -20.0 |
| SPDYE3 | speedy/RINGO cell cycle regulator family member E3 | -20.0 |
| CAPN12 | calpain 12 | -20.0 |
| C3ORF80 | chromosome 3 open reading frame 80 | -20.0 |
| SLC9A6 | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 | -20.0 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 | -20.0 |
| MARS | methionyl-tRNA synthetase | -20.0 |
| GPX3 | glutathione peroxidase 3 | -20.0 |
| SAR1B | secretion associated, Ras related GTPase 1B | -20.0 |
| NUTM2G | NUT family member 2G | -20.0 |
| LRRC4 | leucine rich repeat containing 4 | -20.0 |
| EPHA1 | EPH receptor A1 | -20.0 |
| HDLBP | high density lipoprotein binding protein | -20.0 |
| TMEM186 | transmembrane protein 186 | -20.0 |
| STAB1 | stabilin 1 | -20.0 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -20.0 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) | -20.0 |
| C21ORF2 | chromosome 21 open reading frame 2 | -20.0 |
| PSD | pleckstrin and Sec7 domain containing | -20.0 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -20.0 |
| EFCAB5 | EF-hand calcium binding domain 5 | -20.0 |
| POM121 | POM121 transmembrane nucleoporin | -20.0 |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | -20.0 |
| TAGLN | transgelin | -20.0 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 | -20.0 |
| NUTM2B | NUT family member 2B | -20.0 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -20.0 |
| PAQR4 | progestin and adipoQ receptor family member IV | -20.0 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -20.0 |
| INCA1 | inhibitor of CDK, cyclin A1 interacting protein 1 | -20.0 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit | -20.0 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | -20.0 |
| IL18BP | interleukin 18 binding protein | -20.0 |
| ADCY3 | adenylate cyclase 3 | -20.0 |
| C5ORF45 | chromosome 5 open reading frame 45 | -20.0 |
| TMEM184A | transmembrane protein 184A | -20.0 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | -20.0 |
| ROM1 | retinal outer segment membrane protein 1 | -20.0 |
| ANKDD1A | ankyrin repeat and death domain containing 1A | -20.0 |
| CDC42SE1 | CDC42 small effector 1 | -20.0 |
| NCR3 | natural cytotoxicity triggering receptor 3 | -20.0 |
| FAM122C | family with sequence similarity 122C | -20.0 |
| UBXN6 | UBX domain protein 6 | -19.699 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | -19.699 |
| PMEL | premelanosome protein | -19.699 |
| IFT74 | intraflagellar transport 74 | -19.699 |
| XYLT2 | xylosyltransferase II | -19.699 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -19.5229 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -19.301 |
| ENDOG | endonuclease G | -19.301 |
| SPDYE1 | speedy/RINGO cell cycle regulator family member E1 | -19.301 |
| NIT1 | nitrilase 1 | -19.1549 |
| TMEM223 | transmembrane protein 223 | -19.0458 |
| C17ORF107 | chromosome 17 open reading frame 107 | -18.8861 |
| SLC39A5 | solute carrier family 39 (zinc transporter), member 5 | -18.8239 |
| NUDT17 | nudix (nucleoside diphosphate linked moiety X)-type motif 17 | -18.7447 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -18.5376 |
| CUL7 | cullin 7 | -18.4949 |
| TMEM120B | transmembrane protein 120B | -18.0223 |
| CCDC183 | coiled-coil domain containing 183 | -18.0 |
| CSNK1D | casein kinase 1, delta | -17.9318 |
| TPPP | tubulin polymerization promoting protein | -17.6271 |
| PFKM | phosphofructokinase, muscle | -17.6073 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | -17.2321 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -17.1618 |
| TMEM55B | transmembrane protein 55B | -17.1385 |
