Perturb_13027_KO_RELB_SRP268648 Gene Set

Dataset PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations
Category transcriptomics
Type gene perturbation
Description KO perturbation targeting RELB in monocytic cells U937 cell line (Study accession: SRP268648) (PerturbAtlas)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the Perturb_13027_KO_RELB_SRP268648 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

increased expression

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 9.03435
C5AR1 complement component 5a receptor 1 7.2342
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 4.92623
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 4.37841
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 4.18073
HYDIN HYDIN, axonemal central pair apparatus protein 3.41248
FAIM2 Fas apoptotic inhibitory molecule 2 2.84861
GM2A GM2 ganglioside activator 2.81945
MFAP4 microfibrillar-associated protein 4 2.77007
EGR3 early growth response 3 2.76607
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.73175
HLA-DRA major histocompatibility complex, class II, DR alpha 2.4657
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.37451
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.20202
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 2.11755
MEI1 meiosis inhibitor 1 2.01995
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.91138
KIAA1671 KIAA1671 1.87501
DHRS9 dehydrogenase/reductase (SDR family) member 9 1.7906
CRLF2 cytokine receptor-like factor 2 1.7151
HLA-DMA major histocompatibility complex, class II, DM alpha 1.69254
ARL17B ADP-ribosylation factor-like 17B 1.6184
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.44753
GREB1 growth regulation by estrogen in breast cancer 1 1.44753
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.4301
BHLHE40 basic helix-loop-helix family, member e40 1.4153
SLA2 Src-like-adaptor 2 1.4153
TP53INP2 tumor protein p53 inducible nuclear protein 2 1.4153
VWA5A von Willebrand factor A domain containing 5A 1.4153

decreased expression

Symbol Name Standardized Value
MMD monocyte to macrophage differentiation-associated -3.41248
LZTS1 leucine zipper, putative tumor suppressor 1 -3.41248
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.73175
CCL2 chemokine (C-C motif) ligand 2 -2.61041
CKS1B CDC28 protein kinase regulatory subunit 1B -2.42144
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -2.18243
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.17812
NUP205 nucleoporin 205kDa -1.88418
ORAI2 ORAI calcium release-activated calcium modulator 2 -1.67613
BRAT1 BRCA1-associated ATM activator 1 -1.38279
ETV4 ets variant 4 -1.35403